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About 65,188 results

ALLMedicine™ Immunodeficiency Center

Research & Reviews  22,965 results

A Novel Vpu Adaptive Mutation of HIV-1 Degrades Tetherin in Northern Pig-Tailed Macaque...
https://doi.org/10.1128/jvi.00200-23
Journal of Virology; Lu Y, Pang W et. al.

Mar 28th, 2023 - Tetherin prevents viral cross-species transmission by inhibiting the release of multiple enveloped viruses from infected cells. With the evolution of simian immunodeficiency virus of chimpanzees (SIVcpz), a pandemic human immunodeficiency virus ty...

Immune tolerance breakdown in inborn errors of immunity: Paving the way to novel therap...
https://doi.org/10.1016/j.clim.2023.109302
Clinical Immunology (Orlando, Fla.); Giardino G, Romano R et. al.

Mar 27th, 2023 - Up to 25% of the patients with inborn errors of immunity (IEI) also exhibit immunodysregulatory features. The association of immune dysregulation and immunodeficiency may be explained by different mechanisms. The understanding of mechanisms underl...

Editorial for "Cardiac MRI-Based Assessment of Myocardial Injury in Asymptomatic People...
https://doi.org/10.1002/jmri.28702
Journal of Magnetic Resonance Imaging : JMRI; Roever L, Tse G et. al.

Mar 26th, 2023 - Editorial for "Cardiac MRI-Based Assessment of Myocardial Injury in Asymptomatic People Living With Human Immunodeficiency Virus-Correlation With Nadir CD4".|2023|Roever L,Tse G,Biondi-Zoccai G,|

Clinicopathologic and Molecular Characteristics of Epstein-Barr Virus-Associated Smooth...
https://doi.org/10.1016/j.modpat.2023.100127
Modern Pathology : an Official Journal of the United Stat... Wah NW, Mok Y et. al.

Mar 26th, 2023 - Epstein-Barr virus (EBV)-associated smooth muscle tumors (EBV-SMTs) are rare smooth muscle neoplasms exclusively associated with immunosuppression, such as in patients with HIV/AIDS, posttransplant, and congenital immunodeficiency. However, the ge...

Identification of N6-methylandenosine-related lncRNA for tuberculosis diagnosis in pers...
https://doi.org/10.1016/j.tube.2023.102337
Tuberculosis (Edinburgh, Scotland); Xu S, Yuan H et. al.

Mar 26th, 2023 - Development of a robust diagnostic test for patients co-infected with human immunodeficiency virus and tuberculosis (HIV/TB) is urgently needed. We believe N6-methyladenosine (m6A)- related long non-coding RNA (lncRNAs) from the host blood could b...

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Guidelines  36 results

AGA Clinical Practice Update on Management of Refractory Celiac Disease: Expert Review.
https://doi.org/10.1053/j.gastro.2022.07.086
Gastroenterology Green PHR, Paski S et. al.

Sep 23rd, 2022 - The purpose of this expert review is to summarize the diagnosis and management of refractory celiac disease. It will review evaluation of patients with celiac disease who have persistent or recurrent symptoms, differential diagnosis, nutritional s...

Common Variable Immunodeficiency Disorders, T-Cell Responses to SARS-CoV-2 Vaccines, and the Risk of Chronic COVID-19
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230758/
The Journal of Allergy and Clinical Immunology; Ameratunga R, Longhurst H et. al.

Jun 25th, 2021 - COVID-19 has had a calamitous effect on the global community. Despite intense study, the immunologic response to the infection is only partially understood. In addition to older age and ethnicity, patients with comorbidities including obesity, dia...

Directive clinique no 409 : Tests diagnostiques fœtaux intra-utérins en cas d'infection...
https://doi.org/10.1016/j.jogc.2020.10.006
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Wilson RD

Dec 15th, 2020 - La présente directive clinique révisée met à jour les renseignements sur la prestation de soins aux femmes atteintes d'une infection virale chronique devant se soumettre à un test diagnostique fœtal intra-utérin. Femmes atteintes d'une infection v...

Guideline No. 409: Intrauterine Fetal Diagnostic Testing in Women with Chronic Viral In...
https://doi.org/10.1016/j.jogc.2020.09.007
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Wilson RD

Dec 15th, 2020 - This revised guideline provides updated information for the care of women with chronic viral infections who require intrauterine fetal diagnostic testing. Women with chronic viral infections who are pregnant or planning a pregnancy. Non-invasive s...

Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768745
Clinical Infectious Diseases : an Official Publication Of... Daley CL, Iaccarino JM et. al.

Aug 17th, 2020 - Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline focuses on pulmonary disease in adults (wit...

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Drugs  569 results see all →

Clinicaltrials.gov  1,402 results

Phase 2b, Open-label, Multicenter, Rollover Study to Assess Antiviral Activity and Safety of Long-acting (LA) Cabotegravir (CAB) Plus LA Rilpivirine (RPV), Administered Every 2 Months (Q2M), in Hum...
https://clinicaltrials.gov/ct2/show/NCT03639311

Mar 21st, 2023 - This study (POLAR), is designed to assess the antiviral activity and safety of CAB LA plus RPV LA, administered Q2M, in approximately 100 adult HIV-1 infected, antiretroviral therapy (ART) experienced participants. Participants will rollover from ...

Liver Fibrosis in HIV-Infected Patients With Elevated Liver Enzymes on Antiretroviral Therapy
https://clinicaltrials.gov/ct2/show/NCT00326482

Mar 21st, 2023 - At present, there are no clear guidelines as to when antiretroviral therapy for human immunodeficiency virus (HIV) infection should be stopped in the setting of elevated liver enzymes. In large part, this is due to a limited understanding of the n...

PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects
https://clinicaltrials.gov/ct2/show/NCT03581305

Mar 21st, 2023 - Background: An extensive body of literature points towards neuronal brain injury in human immunodeficiency virus positive (HIV-positive) subjects despite virological suppression of the virus in the periphery under the effect of antiretroviral ther...

Protease Inhibitor vs. Raltegravir-based ART and Inflammation in HIV Infection
https://clinicaltrials.gov/ct2/show/NCT02691065

Mar 21st, 2023 - Human immunodeficiency virus (HIV) infection damages body defence mainly by affecting two important white blood cells called cluster of differentiation (CD4) T cells and monocytes. This immune dysfunction leads to persistent inflammation, which is...

Evaluation of Patients With Immune Function Abnormalities
https://clinicaltrials.gov/ct2/show/NCT00128973

Mar 17th, 2023 - This protocol is designed for the screening and baseline assessment of and collection of research sample from patients with abnormalities of immune function as manifested by recurrent or unusual infections, recurrent or chronic inflammation, or pr...

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News  1,038 results

FDA Greenlights First Drug for Rare Immunodeficiency Disease
https://www.medpagetoday.com/genetics/generalgenetics/103724

Mar 27th, 2023 - The FDA approved leniolisib (Joenja) on Friday as the first treatment indicated for activated phosphoinositide 3-kinase delta syndrome (APDS), a rare genetic disorder that causes progressive primary immunodeficiency. Leniolisib, an oral small mole...

Multimodal Treatment of Epidermodysplasia Verruciformis in an HIV-Positive Man
https://www.mdedge.com/dermatology/article/261553/infectious-diseases/multimodal-treatment-epidermodysplasia-verruciformis
Michelle A. Boettler, BS, Alexander M. Cartron, MD et. al.

Mar 2nd, 2023 - To the Editor: Epidermodysplasia verruciformis (EDV) is a rare generalized form of epidermal dysplasia that is linked to certain subtypes of human papillomavirus (HPV) infection and inherited or acquired states of immunodeficiency. 1-3 The inherite.

Comorbidity Burden in People With HIV Tied to Increased Mortality Risk
https://www.medpagetoday.com/hivaids/hivaids/103078

Feb 13th, 2023 - The prevalence of comorbidities in people with HIV on effective antiretroviral treatment was consistently higher compared with HIV-negative individuals, and was linked to an increased risk for death, according to a prospective longitudinal cohort ...

Trends in Antiretroviral Therapy Eligibility and Coverage Among Children Aged 15 Years with HIV Infection - 20 PEPFAR-Supported Sub-Saharan African Countries, 2012-2016
https://tools.cdc.gov/medialibrary/index.aspx#/media/id/380574

Rapid disease progression and associated opportunistic infections contribute to high mortality rates among children aged <15 years with human immunodeficiency virus (HIV) infection (1). Antiretroviral therapy (ART) has decreased childhood HIV-asso...

HIV Preexposure Prophylaxis in the U.S. Military Services - 2014-2016
https://tools.cdc.gov/medialibrary/index.aspx#/media/id/380650

Human immunodeficiency virus (HIV) infection is a substantial health concern for the U.S. Department of Defense (DoD) and for service members stationed throughout the world. Each year, approximately 350 new HIV infections are diagnosed in members ...

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Patient Education  65 results see all →