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About 13,588 results

ALLMedicine™ Gout Center

Research & Reviews  3,571 results

Outcome reporting in randomized trials in gout: A systematic scoping review from the OM...
https://doi.org/10.1016/j.semarthrit.2023.152191
Seminars in Arthritis and Rheumatism; Morillon MB, Nørup A et. al.

Mar 25th, 2023 - The selection and reporting of core outcome measures in clinical trials is essential for patients, researchers, and healthcare providers for clinical research to have an impact on healthcare. In this systematic scoping review, we aimed to quantify...

Association between gout at midlife and cognitive impairment at late life - The Singapo...
https://doi.org/10.1016/j.archger.2023.104996
Archives of Gerontology and Geriatrics; Tan LF, Li H et. al.

Mar 24th, 2023 - The association between gout and risk of cognitive impairment or dementia is not well established. We examined the relationship between having gout at midlife and the risk of developing cognitive impairment later on. We used data of 16,948 partici...

Unusual Cause of Cord Compression in a Patient with Chronic Lymphocytic Leukemia.
https://doi.org/10.12659/AJCR.938852
The American Journal of Case Reports; Gebreselassie KZ, Valancius D et. al.

Mar 24th, 2023 - BACKGROUND Spinal gout is not so uncommon. The numbers of case reports are low because of underdiagnosis. Nevertheless, the presentation of spinal gout in a patient who was never diagnosed with gout or hyperuricemia is rare. In addition, the proba...

Circumcision
https://emedicine.medscape.com/article/1015820-print

Mar 23rd, 2023 - Background Circumcision of males involves removing the fold of skin that normally covers the glans penis. Although no consensus exists among scholars regarding the origins of circumcision, some have suggested that this procedure likely originated ...

Circumcision
http://emedicine.medscape.com/article/1015820-overview

Mar 23rd, 2023 - Background Circumcision of males involves removing the fold of skin that normally covers the glans penis. Although no consensus exists among scholars regarding the origins of circumcision, some have suggested that this procedure likely originated ...

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Guidelines  10 results

Association Between Gout Flare and Subsequent Cardiovascular Events Among Patients With Gout
https://jamanetwork.com/journals/jama/article-abstract/2794763
JAMA Cipolletta E, Tata LJ et. al.

Aug 2nd, 2022 - Question Among patients with gout, is there a transient increase in the risk of cardiovascular events after gout flares?

2021 Asia-Pacific League of Associations for Rheumatology clinical practice guideline f...
https://doi.org/10.1111/1756-185X.14266
International Journal of Rheumatic Diseases; Lorenzo JPP, Sollano MHMZ et. al.

Dec 22nd, 2021 - Gout is the most prevalent inflammatory arthritis in the Asia-Pacific region and worldwide. This clinical practice guideline (CPG) aims to provide recommendations based on systematically obtained evidence and values and preferences tailored to the...

2020 American College of Rheumatology Guideline for the Management of Gout.
https://doi.org/10.1002/art.41247
Arthritis & Rheumatology (Hoboken, N.J.); FitzGerald JD, Dalbeth N et. al.

May 12th, 2020 - To provide guidance for the management of gout, including indications for and optimal use of urate-lowering therapy (ULT), treatment of gout flares, and lifestyle and other medication recommendations. Fifty-seven population, intervention, comparat...

2020 American College of Rheumatology Guideline for the Management of Gout.
https://doi.org/10.1002/acr.24180
Arthritis Care & Research; FitzGerald JD, Dalbeth N et. al.

May 12th, 2020 - To provide guidance for the management of gout, including indications for and optimal use of urate-lowering therapy (ULT), treatment of gout flares, and lifestyle and other medication recommendations. Fifty-seven population, intervention, comparat...

2018 updated European League Against Rheumatism evidence-based recommendations for the ...
https://doi.org/10.1136/annrheumdis-2019-215315
Annals of the Rheumatic Diseases; Richette P, Doherty M et. al.

Jun 7th, 2019 - Although gout is the most common inflammatory arthritis, it is still frequently misdiagnosed. New data on imaging and clinical diagnosis have become available since the first EULAR recommendations for the diagnosis of gout in 2006. This prompted a...

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Drugs  551 results see all →

Clinicaltrials.gov  324 results

The Re-Prosper HF Study
https://clinicaltrials.gov/ct2/show/NCT04551222

Mar 14th, 2023 - Heart failure with reduced ejection fraction (HFrEF) is a common cause for admission within the Veterans Affairs (VA) Health Care System. It is associated with severe impairment of physical and mental health status and carries a high 5-yr mortalit...

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
https://clinicaltrials.gov/ct2/show/NCT05658575

Mar 8th, 2023 - This is a multi-center Phase 2/3 randomized, double-blind, placebo-controlled, parallel-group safety and efficacy study of dapansutrile (OLT1177®), a specific NLRP3 inhibitor, conducted in subjects with acute gout flare. Up to 300 eligible subject...

Infusion Duration Study To Assess Tolerability of Pegloticase Administered With a Shorter Infusion Duration in Subjects With Uncontrolled Gout Receiving Methotrexate
https://clinicaltrials.gov/ct2/show/NCT04511702

Mar 8th, 2023 - Approximately 180 participants will be enrolled. After a 4-week methotrexate run-in period, participants will be treated for up to 24 weeks with weekly oral methotrexate and biweekly 8mg pegloticase infusions. Up to three pegloticase infusion dura...

A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With Gout
https://clinicaltrials.gov/ct2/show/NCT05007392

Mar 2nd, 2023 - The primary purpose of the study is to confirm the efficacy of dotinurad 4 milligram (mg) to febuxostat 40 mg on the percentage of participants achieving a serum uric acid (SUA) level less than or equal to (<=) 6.0 milligrams per deciliter (mg/dL)...

A Study of Verinurad and Allopurinol in Patients With Chronic Kidney Disease and Hyperuricaemia
https://clinicaltrials.gov/ct2/show/NCT03990363

Mar 2nd, 2023 - Evidence shows independent associations between hyperuricaemia and the risk of hypertension, myocardial infarction, chronic kidney disease (CKD), type 2 diabetes, heart failure, and metabolic syndrome, including obesity Furthermore, gout, an infla...

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News  911 results

Second RSV Vaccine for Older Adults Gets Thumbs Up From FDA Advisors
https://www.medpagetoday.com/infectiousdisease/vaccines/103344

Mar 1st, 2023 - A panel of FDA’s outside advisors recommended the agency approve GSK’s respiratory syncytial virus (RSV) vaccine for older adults, a day after backing Pfizer’s RSV vaccine candidate for that same population. By votes of 12-0 on efficacy and 10-2 o...

Daily Thiazide No Help in Preventing Recurrent Kidney Stones
https://www.medpagetoday.com/nephrology/generalnephrology/103336

Mar 1st, 2023 - A common diuretic wasn't much help for staving off recurrent kidney stones, the NOSTONE trial showed. Over a median follow-up of 2.9 years, symptomatic or radiologic recurrence of kidney stones occurred in 59% of patients who received hydrochlorot...

FDA Flags Potential Guillain-Barre Risk With RSV Vaccine Candidates
https://www.medpagetoday.com/infectiousdisease/vaccines/103297

Feb 27th, 2023 - Ahead of a 2-day meeting with FDA's vaccine advisors, reviewers at the agency highlighted a rare but potential risk for Guillain-Barré syndrome with two vaccine candidates for respiratory syncytial virus (RSV). On Tuesday and Wednesday, the Vaccin...

Their Alzheimer's Disease Didn't Worsen. Why?
https://www.medpagetoday.com/neurology/alzheimersdisease/102961

Feb 3rd, 2023 - Sustained vigorous exercise might have slowed disease progression in two patients with positive Alzheimer's biomarkers and mild cognitive impairment, two case reports suggested. At age 64, patient 1 was diagnosed with amnestic mild cognitive impai...

Novel Gout Drug Passes Mid-Stage Test
https://www.medpagetoday.com/rheumatology/generalrheumatology/102716

Jan 20th, 2023 - An investigational non-purine xanthine oxidase inhibitor for gout treatment, called tigulixostat, appeared effective enough in a phase II trial that a pivotal study is now getting underway. Depending on the dose, 45% to 62% of patients receiving t...

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Patient Education  68 results see all →