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About 9,653 results

ALLMedicine™ Gout Center

Research & Reviews  2,663 results

Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports.
https://doi.org/10.1097/MD.0000000000028418
Medicine Wu Z, Liu C et. al.

Jan 15th, 2022 - Intraspinal gout tophus in the lumbar vertebral canal associated with gouty arthritis is rare. We present 2 cases with the first manifestations of a sequestrated intervertebral disc and an extradural tumor, and histopathologically proven to be gou...

A Study to Assess Efficay and Safety of LC350189 Different Doses in Gout Patients With Hyperuricemia
https://clinicaltrials.gov/ct2/show/NCT03934099

Jan 13th, 2022 - The aim of this 12-week randomized multicenter double-blind parallel group placebo-controlled dose finding study is to assess the efficacy and safety of three different doses of LC350189 in subjects with hyperuricemia and a diagnosis of gout.

Genetic association studies of the progression from hyperuricemia to gout.
https://doi.org/10.1093/rheumatology/keac011
Rheumatology (Oxford, England); Sumpter NA, Takei R et. al.

Jan 13th, 2022 - Genetic association studies of the progression from hyperuricemia to gout.|2022|Sumpter NA,Takei R,Leask MP,Reynolds RJ,Merriman TR,|

Inflammation in obesity, diabetes, and related disorders.
https://doi.org/10.1016/j.immuni.2021.12.013
Immunity Rohm TV, Meier DT et. al.

Jan 13th, 2022 - Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state contributes to long-term complications of diabetes, including non-al...

Illness perception and treatment experience in patients with gout: a descriptive qualit...
https://doi.org/10.1007/s10067-021-06014-w
Clinical Rheumatology; Li Q, Liu T et. al.

Jan 12th, 2022 - To explore the illness perception and treatment experience of gout patients in China. A descriptive qualitative approach was used. In-depth semi-structured individual interviews were conducted among 18 adults with gout between August 2020 and Dece...

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Guidelines  7 results

2020 American College of Rheumatology Guideline for the Management of Gout.
https://doi.org/10.1002/art.41247
Arthritis & Rheumatology (Hoboken, N.J.); FitzGerald JD, Dalbeth N et. al.

May 12th, 2020 - To provide guidance for the management of gout, including indications for and optimal use of urate-lowering therapy (ULT), treatment of gout flares, and lifestyle and other medication recommendations. Fifty-seven population, intervention, comparat...

2018 updated European League Against Rheumatism evidence-based recommendations for the ...
https://doi.org/10.1136/annrheumdis-2019-215315
Annals of the Rheumatic Diseases; Richette P, Doherty M et. al.

Jun 7th, 2019 - Although gout is the most common inflammatory arthritis, it is still frequently misdiagnosed. New data on imaging and clinical diagnosis have become available since the first EULAR recommendations for the diagnosis of gout in 2006. This prompted a...

The British Society for Rheumatology Guideline for the Management of Gout.
https://doi.org/10.1093/rheumatology/kex156
Rheumatology (Oxford, England); Hui M, Carr A et. al.

May 27th, 2017 - The British Society for Rheumatology Guideline for the Management of Gout.|2017|Hui M,Carr A,Cameron S,Davenport G,Doherty M,|diet therapy,drug therapy,therapy,therapeutic use,

ACR Appropriateness Criteria® Chronic Extremity Joint Pain-Suspected Inflammatory Arthr...
https://doi.org/10.1016/j.jacr.2017.02.006
Journal of the American College of Radiology : JACR; , Jacobson JA et. al.

May 6th, 2017 - Evaluation for suspected inflammatory arthritis as a cause for chronic extremity joint pain often relies on imaging. This review first discusses the characteristic osseous and soft tissue abnormalities seen with inflammatory arthritis and how they...

Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Phy...
https://doi.org/10.7326/M16-0569
Annals of Internal Medicine; Qaseem A, McLean RM et. al.

Nov 2nd, 2016 - The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the diagnosis of gout. This guideline is based on a systematic review of published studies on gout diagnosis, identif...

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Drugs  414 results see all →

Clinicaltrials.gov  106 results

A Study to Assess Efficay and Safety of LC350189 Different Doses in Gout Patients With Hyperuricemia
https://clinicaltrials.gov/ct2/show/NCT03934099

Jan 13th, 2022 - The aim of this 12-week randomized multicenter double-blind parallel group placebo-controlled dose finding study is to assess the efficacy and safety of three different doses of LC350189 in subjects with hyperuricemia and a diagnosis of gout.

CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat
https://clinicaltrials.gov/ct2/show/NCT02579096

Jan 11th, 2022 - Gout is the most common form of inflammatory arthritis affecting adults (1), with a disease frequency that continues to increase dramatically (2). Gout is associated with substantial morbidity and mortality which are concentrated in older men and ...

Phase 2b Evaluation of Efficacy and Safety of AR882 in Gout Patients
https://clinicaltrials.gov/ct2/show/NCT05119686

Dec 13th, 2021 - This study will assess the serum uric acid lowering effect and safety of AR882 in gout patients at two doses compared to placebo over 12 weeks.

Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Disease
https://clinicaltrials.gov/ct2/show/NCT04987294

Dec 6th, 2021 - This is a randomized, double-blind, placebo-controlled parallel group, multi-center phase II clinical study or orally administered ALLN-346 in subjects with hyperuricemia, gout and mild to moderate chronic kidney disease over a two-week period. Su...

Ketotifen and Indomethacin Combination Treatment Clinical Trial for COVID-19
https://clinicaltrials.gov/ct2/show/NCT05007522

Nov 26th, 2021 - Coronavirus Disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which is a recently emerged coronavirus that has resulted in an ongoing global pandemic. Fever and cough are most commonly experienced a...

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News  640 results

Super-Low Uric Acid May Not Be Best for Erosive Gout
https://www.medscape.com/viewarticle/966416

Jan 11th, 2022 - Lowering the serum urate target to less than 0.20 mmol/L (<3.6 mg/dL) for patients with erosive gout does not achieve better gout outcomes and leads to more medication use and subsequent side effects, according to findings from a 2-year, double-bl...

Genes and Extra Weight Tied to Higher Gout Risk in Women
https://www.medpagetoday.com/rheumatology/generalrheumatology/96052

Dec 7th, 2021 - Excess adiposity and genetic predisposition both contributed to risk of gout among U.S. women, with the risks being highest when both factors are present, a large prospective study found. Analysis of data from the Nurses' Health Study (NHS) found ...

Does Meta-Analysis Slam the Door on Colchicine for COVID-19?
https://www.medpagetoday.com/infectiousdisease/covid19/95836

Nov 23rd, 2021 - Adding colchicine (Colcrys) to current standard of care COVID treatment was not associated with any benefit, but it was associated with more adverse events, a meta-analysis found. In a pooled analysis involving six intention-to-treat studies, colc...

Another Study Confirms Gout Benefit With SGLT2 Inhibitors
https://www.medpagetoday.com/endocrinology/diabetes/95777

Nov 19th, 2021 - Patients with type 2 diabetes taking sodium-glucose cotransporter-2 (SGLT2) inhibitors saw a lower risk for gout, a Taiwanese cohort study found. Compared with patients taking DPP-4 inhibitors, those on an SGLT2 inhibitor had an 11% reduced risk f...

New Jardiance Indication? Bariatric Surgery for NASH; ICER Reviews Tirzepatide
https://www.medpagetoday.com/endocrinology/generalendocrinology/95628

Nov 14th, 2021 - The FDA accepted a supplemental new drug application for empagliflozin (Jardiance) as a treatment for heart failure independent of left ventricular ejection fraction in patients with or without diabetes based on the phase III EMPEROR-Preserved tri...

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Patient Education  31 results see all →