ALLMedicine™ Osteomyelitis Center

Mar 28th, 2023 - While recent studies showed that macrophages are critical for bone fracture healing, and lack of M2 macrophages have been implicated in models of delayed union, functional roles for specific M2 receptors have yet to be defined. Moreover, the M2 sc...

Mar 25th, 2023 - Plasmacytoma is a rare plasma cell dyscrasia that grows within the axial skeleton or soft tissue structures as solitary or multiple masses. The primary types are solitary plasmacytoma, including solitary bone plasmacytoma (SBP) and solitary extram...

Mar 24th, 2023 - Treatment of osteomyelitis is hampered by a paucity of evidence from prospective clinical trials with randomized treatment arms. Furthermore, previous randomized or observational trials have enrolled small numbers of subjects and thus often had no...

Mar 24th, 2023 - This is a Phase 2b clinical study, multicenter, randomized, open-label, assessor-blinded, superiority study. The study will compare dalbavancin to standard of care antibiotic therapy for the completion of therapy in patients with complicated bacte...

Mar 23rd, 2023 - Streptococcus gallinaceus is a new species of Streptococcus that was first isolated in 2004 in chickens. Infections in humans are associated with chicken exposure. There are very few case reports of human infections with this organism and none wit...

Nov 28th, 2022 - Musculoskeletal infections involve bones, joints, and soft tissues. These infections are a common clinical scenario in both outpatient and emergent settings. Although radiography provides baseline findings, a multimodality approach is often implem...

May 14th, 2022 - Imaging plays an integral role in the evaluation of suspected musculoskeletal infections in children, not only in the accurate identification of infection such as osteomyelitis or septic arthritis, but also in guiding management. Various diagnosti...

Aug 6th, 2021 - This clinical practice guideline for the diagnosis and treatment of acute hematogenous osteomyelitis (AHO) in children was developed by a multidisciplinary panel representing Pediatric Infectious Diseases Society (PIDS) and the Infectious Diseases...

Nov 6th, 2018 - Imaging plays in important role in the evaluation of the acutely limping child. The decision-making process about initial imaging must consider the level of suspicion for infection and whether symptoms can be localized. The appropriateness of spec...

May 6th, 2017 - Infection of the musculoskeletal system is a common clinical problem. Differentiating soft tissue from osseous infection often determines the appropriate clinical therapeutic course. Radiographs are the recommend initial imaging examination, and a...

Mar 24th, 2023 - Treatment of osteomyelitis is hampered by a paucity of evidence from prospective clinical trials with randomized treatment arms. Furthermore, previous randomized or observational trials have enrolled small numbers of subjects and thus often had no...

Mar 24th, 2023 - This is a Phase 2b clinical study, multicenter, randomized, open-label, assessor-blinded, superiority study. The study will compare dalbavancin to standard of care antibiotic therapy for the completion of therapy in patients with complicated bacte...

Mar 7th, 2023 - Through the use of a pro- and retrospective registry, the investigators will collect information on patient characteristics including age, co-morbidities, imaging and biopsy information, and prior treatments. Information on treatment details will ...

Mar 1st, 2023 - The purpose of this European, multicentric, prospective, non-interventional study is to document and evaluate the efficacy and safety of the treatment of severely infected patients with intravenously administered fosfomycin, including patients wit...

Mar 1st, 2023 - Trial 1: At enrollment (Day 1), the investigator will prescribe empiric antibiotic treatment based on instructions provided in the protocol and determine the most appropriate route of administration (oral or IV) according to the patient's conditio...

Mar 23rd, 2023 - The FDA gave the greenlight to the long-acting antifungal rezafungin (Rezzayo), the first new treatment option for candidemia and invasive candidiasis to gain approval in over a decade, Cidara Therapeutics and Melinta Therapeutics announced on Wed...

Feb 17th, 2023 - Older patients prescribed an atypical antipsychotic for hospitalization-related delirium more often stayed on it past the recommended duration than if prescribed a typical antipsychotic, researchers reported. Among nearly 6,000 patients 65 and old...

Jan 13th, 2023 - Vancomycin is a commonly used glycopeptide antibiotic used to treat infections caused by gram-positive organisms. Vancomycin is most often used as a parenteral agent for empiric or definitive treatment of methicillin-resistant Staphylococcus aureu.

Dec 22nd, 2022 - The patient is diagnosed with atopic dermatitis (AD) complicated by skin infection. AD is the most common chronic pruritic inflammatory skin disorder that affects both children and adults.

Nov 18th, 2022 - PHILADELPHIA — An international group of researchers has proposed the first classification criteria for chronic nonbacterial osteomyelitis (CNO) and a severe form of it, chronic recurrent multifocal osteomyelitis (CRMO). CNO/CRMO most frequently a...