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About 40,860 results

ALLMedicine™ Osteoporosis Center

Research & Reviews  13,394 results

NAP1L2 drives mesenchymal stem cell senescence and suppresses osteogenic differentiation.
https://doi.org/10.1111/acel.13551
Aging Cell; Hu M, Xing L et. al.

Jan 16th, 2022 - Senescence of bone marrow mesenchymal stem cells (BMSCs) impairs stemness and osteogenic differentiation, but the key regulators for senescence and the related osteogenesis are not well defined. Herein, we screened the gene expression profiles of ...

Combination of molecular docking and liver transcription sequencing analysis for the ev...
https://doi.org/10.1016/j.jep.2021.114955
Journal of Ethnopharmacology; Wu Y, Min L et. al.

Jan 16th, 2022 - Salt-processed Psoraleae fructus (SPF) is widely used as a phytoestrogen-like agent in the treatment of osteoporosis. However, SPF-associated hepatotoxicity is a known health hazard. Cholestasis is often associated with SPF-induced hepatotoxicity....

Evaluating Patients for Secondary Causes of Osteoporosis.
https://doi.org/10.1007/s11914-022-00717-y 10.1016/j.jocd.2019.07.001 10.1007/s00198-014-2655-z 10.1007/s00198-011-1713-z 10.3109/13697137.2015.1103615 10.4158/EP.12.4.436 10.1210/jc.2002-020275 10.1210/jc.2002-021996 10.1016/S0025-6196(11)62214-3 10.1530/EJE-10-0015 10.1007/s11914-019-00529-7 10.1002/jbmr.1565 10.1359/jbmr.081253 10.1016/B978-0-12-813073-5.00061-7 10.1080/17446651.2019.1575727 10.1007/s00198-014-2794-2 10.1097/gme.0b013e3181c617e6 10.1136/injuryprev-2020-044014 10.1007/s00198-010-1524-7 10.1007/s00198-020-05517-7 10.1002/jbmr.2849 10.1007/s00223-016-0191-x 10.1007/s00198-010-1461-5 10.1002/jbmr.3124 10.1002/jbmr.2017 10.1002/jbmr.4139 10.1378/chest.121.2.609 10.1186/s11556-020-00255-5 10.1519/JPT.0000000000000099 10.1371/journal.pone.0176946 10.1503/cmaj.100771 10.1007/s11657-017-0324-5 10.1007/s00198-019-05261-7 10.4158/EP.12.1.48 10.1210/jc.2014-1413 10.3399/bjgp20X710717 10.1136/bmj.4.5893.643 10.1186/1472-6890-8-12 10.1111/cen.14326 10.1111/cen.14362 10.1111/j.1525-139X.2010.00735.x 10.1097/00000441-200306000-00006 10.1002/jbmr.3657 10.1002/jbm4.10447 10.1016/j.bone.2017.02.011 10.7326/M17-2640 10.7326/M16-2752 10.1038/ki.2008.356 10.1038/ki.2008.193 10.1210/jc.2011-0385 10.1111/nyas.13968 10.1007/s00198-008-0650-y 10.1359/jbmr.090819 10.3109/00365598309182139 10.1016/j.clinbiochem.2008.03.002 10.1016/j.cca.2011.08.033 10.1002/jbmr.2467 10.1016/j.abb.2010.06.026 10.3949/ccjm.85a.16090 10.1016/S0140-6736(17)31430-7 10.1007/s40520-020-01678-x 10.1007/s00198-020-05615-6 10.1016/S1297-319X(00)00207-4 10.1038/ki.1991.151 10.1016/j.ajog.2008.06.009 10.1210/jc.2018-01225 10.1210/jc.2015-3907 10.3803/EnM.2021.1061 10.1097/MPG.0000000000002497 10.1210/jc.2011-3045 10.1530/EJE-16-0289 10.1210/jc.2008-0125 10.1002/ajh.26118 10.1002/jbmr.2387 10.1093/rheumatology/kez127 10.1016/j.jocd.2019.09.006 10.1210/jendso/bvaa148 10.1007/s00198-020-05734-0 10.1016/j.cca.2016.06.036 10.2215/CJN.02430508 10.3389/fendo.2020.00399
Current Osteoporosis Reports; Lewiecki EM

Jan 16th, 2022 - This review provides suggestions for the evaluation of patients with osteoporosis in order to assure that the diagnosis is correct, to identify potentially correctable conditions contributing to skeletal fragility and fracture risk, and to assist ...

Intertrochanteric hip stress fracture in a male ultramarathon runner.
https://doi.org/10.1136/bcr-2020-239594
BMJ Case Reports; Nadwodny JP, Pujalte G et. al.

Jan 15th, 2022 - Stress fractures are injuries frequently seen in high-performance athletes, especially runners. In the femur, the most commonly affected locations are the femoral neck, condylar area and proximal shaft. Intertrochanteric fractures are much more co...

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Guidelines  62 results

Management guideline for Werner syndrome 2020. 4. Osteoporosis associated with Werner s...
https://doi.org/10.1111/ggi.14078
Geriatrics & Gerontology International; Mori S, Takemoto M et. al.

Nov 7th, 2020 - Management guideline for Werner syndrome 2020. 4. Osteoporosis associated with Werner syndrome.|2020|Mori S,Takemoto M,Kubota Y,Taniguchi T,Motegi SI,|methods,therapeutic use,diagnosis,etiology,prevention & control,complications,diagnosis,drug the...

Ankle fractures in the elderly: Current concepts.
https://doi.org/10.1016/j.injury.2020.10.093
Injury Pearce O, Al-Hourani K et. al.

Nov 7th, 2020 - Ankle fractures remain the third most common musculoskeletal injury in the elderly population. The presence of osteoporosis, significant multiple comorbidities and limited functional independence makes treatment of such injuries challenging. Early...

Medical Care of Adults With Down Syndrome: A Clinical Guideline.
https://doi.org/10.1001/jama.2020.17024
JAMA Tsou AY, Bulova P et. al.

Oct 21st, 2020 - Down syndrome is the most common chromosomal condition, and average life expectancy has increased substantially, from 25 years in 1983 to 60 years in 2020. Despite the unique clinical comorbidities among adults with Down syndrome, there are no cli...

Core principles for fracture prevention: North American Consensus from the National Ost...
https://doi.org/10.1007/s00198-020-05541-7
Osteoporosis International : a Journal Established as Res... Lewiecki EM, Binkley N et. al.

Jul 18th, 2020 - Core principles for fracture prevention address fundamental concepts for the evaluation and management of patients at risk for fracture. These are intended to form the foundation of clinical practice guidelines and represent a first step toward gu...

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS/AMERICAN COLLEGE OF ENDOCRINOLOGY CLI...
https://doi.org/10.4158/GL-2020-0524SUPPL
Endocrine Practice : Official Journal of the American Col... Camacho PM, Petak SM et. al.

May 20th, 2020 - Objective: The development of these guidelines is sponsored by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees and adheres with published AACE protocols ...

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Drugs  257 results see all →

Clinicaltrials.gov  565 results

Zoledronic Acid as Adjuvant Therapy in Neovascular Age-related Macular Degeneration (Z-AMD)
https://clinicaltrials.gov/ct2/show/NCT04304755

Jan 13th, 2022 - This is a one-year, randomized, controlled pilot study. A total of 40 treatment-naïve nAMD patients will be allocated 1:1 to receive an intravenous infusion of either zoledronic acid (ZA) 5 mg or placebo at baseline and after 26 weeks as adjuvant ...

Long-Term Follow-Up of Survivors of Pediatric Cushing Disease
https://clinicaltrials.gov/ct2/show/NCT03831958

Jan 12th, 2022 - Objective: Cushing Disease (CD) describes the state of hypercortisolemia secondary to cortisol producing pituitary adenomas. The rarity of the disease (2-5 new cases per million, 1 out of 10 in children) and the subtle initial findings result in p...

Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover
https://clinicaltrials.gov/ct2/show/NCT05151484

Jan 11th, 2022 - Osteoporosis is a health problem of major proportions. It affects more than 40 million Americans and results in more than 2 million fractures annually among Medicare patients alone. Hospital admissions for osteoporotic fractures exceed those of he...

Comparative Efficacy and Safety Study of RGB-14-P and Prolia in Women With Postmenopausal Osteoporosis
https://clinicaltrials.gov/ct2/show/NCT05087030

Jan 10th, 2022 - This is a randomized, double-blind, multicentre, multiple fixed-dose, 2-arm parallel-group study that includes 2 periods as: Main period (52 weeks), consists of Treatment Period 1 (26 weeks) and Treatment Period 2 (26 weeks). On Day 1 of Treatment...

The Effect of Horizontal Whole-body Vibration Therapy in Post-menopausal Women
https://clinicaltrials.gov/ct2/show/NCT05182281

Jan 10th, 2022 - In this prospective, randomized controlled 3-month study, 185 post-menopausal women who were diagnosed with osteoporosis and followed up in our outpatient clinic based on the osteoporosis diagnostic criteria by the World Health Organization were a...

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News  1,977 results

Endocrine Society Fights Racism; Bisphosphonate Holiday; Tirzepatide Dual Branding?
https://www.medpagetoday.com/endocrinology/generalendocrinology/96690

Jan 16th, 2022 - An Endocrine Society policy perspective is calling for new policies aimed at fighting racial and ethnic inequities in the endocrinology workforce, as well as in access to care. "As endocrinologists, we have a responsibility to take actions to elim...

Expert Panel Develops Quality Indicators for Diagnosis and Treatment of Primary Hyperparathyroidism
https://www.medscape.com/viewarticle/966484

Jan 13th, 2022 - NEW YORK (Reuters Health) - An expert panel has developed quality indicators (QIs) for the diagnosis and management for primary hyperparathyroidism (pHPT), which they hope will help optimize quality and cost-effectiveness of care for patients. "To...

How Safe Is a Drug Holiday From Bisphosphonates for Osteoporosis?
https://www.medscape.com/viewarticle/966526

Jan 13th, 2022 - Researchers found a small but greater risk of a hip fracture after 2 years of taking a "drug holiday" — stopping therapy — after long-term (≥ 3-year) use of one bisphosphonate, risedronate, versus another, alendronate.    The risk of a hip fractur...

FDA Grants Fast Track Designation to Enobosarm for AR+/ER+ Metastatic Breast Cancer
https://www.onclive.com/view/fda-grants-fast-track-designation-to-enobosarm-for-ar-er-metastatic-breast-cancer

Jan 10th, 2022 - The FDA has granted a fast track designation to enobosarm as a potential therapeutic option for patients with androgen receptor (AR)–positive, estrogen receptor (ER)–positive, HER2-negative, metastatic breast cancer who progressed on a nonsteroida...

COVID & Childhood Obesity; Phase III Oral Octreotide Success; Anti-Fog Chemicals
https://www.medpagetoday.com/endocrinology/generalendocrinology/96566

Jan 9th, 2022 - According to new CDC research, COVID-19 is a much greater threat to kids with obesity, with the average length of their hospital stay double that of kids without obesity. (Morbidity and Mortality Weekly Report) A new phase III trial found that ora...

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Patient Education  89 results see all →