ALLMedicine™ Amyotrophic Lateral Sclerosis Center
Research & Reviews 15,861 results
https://doi.org/10.1002/mus.27244
Muscle & Nerve; Perry BJ, Nelson J et. al.
Apr 14th, 2021 - Dysphagia worsens mortality and quality of life for persons diagnosed with amyotrophic lateral sclerosis (ALS), yet our understanding of its incidence and timing remains limited. We sought to estimate dysphagia incidence and dysphagia-free surviva...
https://doi.org/10.1097/WNR.0000000000001636
Neuroreport Muraoka Y, Nikaido A et. al.
Apr 14th, 2021 - Mutations in the factor-induced-gene 4 (FIG 4) gene are associated with multiple disorders, including Charcot-Marie-Tooth disease (CMT), epilepsy with polymicrogyria, Yunis-Varón syndrome and amyotrophic lateral sclerosis. The wide spectrum of dis...
https://doi.org/10.1186/s12883-021-02185-w 10.14336/ad.2013.0400295 10.12871/00039829201741 10.1080/17482960601044106 10.1001/archneur.64.3.330 10.1016/s1474-4422(07)70265-x 10.1080/21678421.2016.1267768 10.1016/s1474-4422(13)70026-7 10.3109/21678421.2013.805784 10.1371/journal.pone.0182002 10.1001/jamaneurol.2017.2255 10.1016/j.jneuroim.2007.10.020 10.1080/146608200300079536 10.1016/s0022-510x(99)00210-5 10.1038/npjparkd.2015.14 10.1002/jlb.1ru1117-428r 10.1097/00005072-199801000-00001 10.1016/j.bbi.2007.12.008 10.1073/pnas.0402268101 10.1016/j.bbi.2013.08.013 10.1038/nrn.2017.39 10.3389/fncel.2014.00021 10.1016/j.brainres.2009.09.018 10.1016/j.brainres.2007.04.044 10.1016/0165-5728(84)90042-0 10.1016/j.brainres.2012.05.056 10.1002/mus.10191 10.1016/j.neurobiolaging.2013.10.001 10.2174/156720510790274392 10.1093/ageing/afn102
BMC Neurology; Yang Y, Pan D et. al.
Apr 13th, 2021 - ALS patients have changed peripheral immunity. It is unknown whether peripheral immunity is related to cognitive dysfunction in ALS patients. To explore the relationship between the peripheral blood lymphocyte subsets and the cognitive status in A...
https://doi.org/10.1159/000513482
Audiology & Neuro-otology; Bombaci A, Lazzaro C et. al.
Apr 13th, 2021 - Amyotrophic lateral sclerosis (ALS) is a neuromuscular progressive disorder, characterized by limb and bulbar muscle wasting and weakness. 30% of patients present a bulbar onset, while 70% a spinal outbreak, although most of them develop bulbar im...
https://doi.org/10.1016/j.ymthe.2021.04.008
Molecular Therapy : the Journal of the American Society O... Amado DA, Davidson BL
Apr 11th, 2021 - Amyotrophic lateral sclerosis (ALS) has historically posed unique challenges for gene therapy-based approaches, due to a paucity of therapeutic targets as well as the difficulty of accessing both the brain and spinal cord. Recent advances in our u...
Guidelines 9 results
http://aquestive.com/aquestive-therapeutics-receives-fda-approval-for-exservan-riluzole-oral-film/
Nov 24th, 2019 - Aquestive Therapeutics, Inc. (NASDAQ: AQST), a specialty pharmaceutical company focused on developing and commercializing differentiated products to solve therapeutic problems, today announced that Exservan™ (riluzole) Oral Film received early-act...
https://doi.org/10.1002/mus.26408
Muscle & Nerve; Pattee GL, Plowman EK et. al.
Jan 8th, 2019 - Universally established comprehensive clinical bulbar scales objectively assessing disease progression in amyotrophic lateral sclerosis (ALS) are currently lacking. The goal of this working group project is to design a best practice set of provisi...
https://www.mda.org/services/neuromuscular-disease-registry
Muscular Dystrophy Association (USA)
Dec 31st, 2015 - In 2013, MDA launched the U. S.
https://doi.org/10.1111/j.1468-1331.2011.03501.x
European Journal of Neurology; , Andersen PM et. al.
Sep 14th, 2011 - The evidence base for the diagnosis and management of amyotrophic lateral sclerosis (ALS) is weak. To provide evidence-based or expert recommendations for the diagnosis and management of ALS based on a literature search and the consensus of an exp...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764728
Neurology Miller RG, Jackson CE et. al.
Oct 13th, 2009 - To systematically review evidence bearing on the management of patients with amyotrophic lateral sclerosis (ALS). The authors analyzed studies from 1998 to 2007 to update the 1999 practice parameter. Topics covered in this section include breaking...
Drugs 31 results see all →
Clinicaltrials.gov 16,271 results
https://doi.org/10.1002/mus.27244
Muscle & Nerve; Perry BJ, Nelson J et. al.
Apr 14th, 2021 - Dysphagia worsens mortality and quality of life for persons diagnosed with amyotrophic lateral sclerosis (ALS), yet our understanding of its incidence and timing remains limited. We sought to estimate dysphagia incidence and dysphagia-free surviva...
https://doi.org/10.1097/WNR.0000000000001636
Neuroreport Muraoka Y, Nikaido A et. al.
Apr 14th, 2021 - Mutations in the factor-induced-gene 4 (FIG 4) gene are associated with multiple disorders, including Charcot-Marie-Tooth disease (CMT), epilepsy with polymicrogyria, Yunis-Varón syndrome and amyotrophic lateral sclerosis. The wide spectrum of dis...
https://doi.org/10.1186/s12883-021-02185-w 10.14336/ad.2013.0400295 10.12871/00039829201741 10.1080/17482960601044106 10.1001/archneur.64.3.330 10.1016/s1474-4422(07)70265-x 10.1080/21678421.2016.1267768 10.1016/s1474-4422(13)70026-7 10.3109/21678421.2013.805784 10.1371/journal.pone.0182002 10.1001/jamaneurol.2017.2255 10.1016/j.jneuroim.2007.10.020 10.1080/146608200300079536 10.1016/s0022-510x(99)00210-5 10.1038/npjparkd.2015.14 10.1002/jlb.1ru1117-428r 10.1097/00005072-199801000-00001 10.1016/j.bbi.2007.12.008 10.1073/pnas.0402268101 10.1016/j.bbi.2013.08.013 10.1038/nrn.2017.39 10.3389/fncel.2014.00021 10.1016/j.brainres.2009.09.018 10.1016/j.brainres.2007.04.044 10.1016/0165-5728(84)90042-0 10.1016/j.brainres.2012.05.056 10.1002/mus.10191 10.1016/j.neurobiolaging.2013.10.001 10.2174/156720510790274392 10.1093/ageing/afn102
BMC Neurology; Yang Y, Pan D et. al.
Apr 13th, 2021 - ALS patients have changed peripheral immunity. It is unknown whether peripheral immunity is related to cognitive dysfunction in ALS patients. To explore the relationship between the peripheral blood lymphocyte subsets and the cognitive status in A...
https://doi.org/10.1159/000513482
Audiology & Neuro-otology; Bombaci A, Lazzaro C et. al.
Apr 13th, 2021 - Amyotrophic lateral sclerosis (ALS) is a neuromuscular progressive disorder, characterized by limb and bulbar muscle wasting and weakness. 30% of patients present a bulbar onset, while 70% a spinal outbreak, although most of them develop bulbar im...
https://doi.org/10.1016/j.ymthe.2021.04.008
Molecular Therapy : the Journal of the American Society O... Amado DA, Davidson BL
Apr 11th, 2021 - Amyotrophic lateral sclerosis (ALS) has historically posed unique challenges for gene therapy-based approaches, due to a paucity of therapeutic targets as well as the difficulty of accessing both the brain and spinal cord. Recent advances in our u...
News 457 results
https://www.medscape.com/viewarticle/947504
Mar 14th, 2021 - "Symptoms, then, are in reality nothing but a cry from suffering organs" – Jean-Martin Charcot Nearly 130 years after his death, Jean-Martin Charcot's name still resonates with modern neurologists. The famed 19th century French physician made myri...
https://www.medscape.com/viewarticle/947056
Mar 10th, 2021 - NEW YORK (Reuters Health) - A new compound, NU-9, improved diseased upper motor neurons (UMN) in mice and shows promise for treating amyotrophic lateral sclerosis (ALS) in humans, though more work is needed before a clinical trial can be started, ...
https://www.medscape.com/viewarticle/944474
Jan 20th, 2021 - Anita Baron first noticed something was wrong in August 2018, when she began to drool. Her dentist chalked it up to a problem with her jaw. Then her speech became slurred. She managed to keep her company, which offers financing to small businesses...
https://www.staging.medscape.com/viewarticle/938926
Oct 14th, 2020 - NEW YORK (Reuters Health) - Amyotrophic lateral sclerosis (ALS) patients prescribed edaravone are hospitalized more frequently, a new surveillance study in U.S. military veterans shows. Patients on edaravone had significantly higher rates of all-c...
https://www.medscape.com/viewarticle/938926
Oct 14th, 2020 - NEW YORK (Reuters Health) - Amyotrophic lateral sclerosis (ALS) patients prescribed edaravone are hospitalized more frequently, a new surveillance study in U.S. military veterans shows. Patients on edaravone had significantly higher rates of all-c...