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About 25,700 results

ALLMedicine™ Epilepsy Center

Research & Reviews  11,813 results

Progressive myoclonic epilepsy: myoclonic epilepsy and ataxia due to KCNC1 mutation (ME...
https://doi.org/10.1684/epd.2020.1197
Epileptic Disorders : International Epilepsy Journal with Videotape; Barot N, Margiotta M et. al.

Sep 25th, 2020 - Progressive myoclonic epilepsy (PME) is characterized by prominent myoclonus and generalized or focal seizures. A recently described novel KCNC1 mutation is associated with a specific phenotype of progressive myoclonic epilepsy, which has been def...

Pharmacological treatment and SUDEP risk: A nationwide population-based case-control st...
https://doi.org/10.1212/WNL.0000000000010874
Neurology Sveinsson O, Andersson T et. al.

Sep 24th, 2020 - We conducted a nationwide case-control study in Sweden to test the hypothesis that antiepileptic drugs (AEDs), mono- polytherapy, adherence, antidepressants, neuroleptics, beta-blockers, and statins are associated with sudden unexpected death in e...

The Effect of Epilepsy and Antiepileptic Drugs on Cortical Motor Excitability in Patien...
https://doi.org/10.1097/WNF.0000000000000412
Clinical Neuropharmacology; Hamed SA, Tohamy AM et. al.

Sep 24th, 2020 - Transcranial magnetic stimulation (TMS) has been used to assess cortical disinhibition/excitation with epilepsy and determine the degree of patients' response to antiepileptic drugs (AEDs). However, the results of studies are variable and conflict...

A Novel Mouse Model for Pyridoxine-Dependent Epilepsy Due to Antiquitin Deficiency.
https://doi.org/10.1093/hmg/ddaa202
Human Molecular Genetics; Al-Shekaili HH, Petkau TL et. al.

Sep 24th, 2020 - Pyridoxine-dependent epilepsy (PDE) is a rare autosomal recessive disease caused by mutations in the ALDH7A1 gene leading to blockade of the lysine catabolism pathway. PDE is characterized by recurrent seizures that are resistant to conventional a...

Epilepsy syndromes, etiologies, and the use of next-generation sequencing in epilepsy p...
https://doi.org/10.1111/epi.16701
Epilepsia REFERENCES; Stödberg T, Tomson T et. al.

Sep 23rd, 2020 - Population-based data on epilepsy syndromes and etiologies in early onset epilepsy are scarce. The use of next-generation sequencing (NGS) has hitherto not been reported in this context. The aim of this study is to describe children with epilepsy ...

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Guidelines  23 results

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005756
Neurology Kanner AM, Ashman E et. al.

Jun 14th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and ris...
https://doi.org/10.1212/WNL.0000000000003685
Neurology Harden C, Tomson T et. al.

Apr 25th, 2017 - To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. Systematic review of evidence; modified Grading Reco...

Cavernoma-related epilepsy: review and recommendations for management--report of the Su...
https://doi.org/10.1111/epi.12402
Epilepsia Rosenow F, Alonso-Vanegas MA et. al.

Oct 18th, 2013 - Cerebral cavernous malformations (CCMs) are well-defined, mostly singular lesions present in 0.4-0.9% of the population. Epileptic seizures are the most frequent symptom in patients with CCMs and have a great impact on social function and quality ...

Evidence-based guideline update: Vagus nerve stimulation for the treatment of epilepsy: Repo...
https://www.aesnet.org/sites/default/files/file_attach/Guidelines/Neurology-2013-Morris-1453-9.pdf
George L. Morris III

Aug 27th, 2013 - VNS may be considered for seizures in children, for LGS-associated seizures, and for improving mood in adults with epilepsy (Level C). VNS may be considered to have improved efficacy over time (Level C).

Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review)...
https://doi.org/10.1111/j.1528-1167.2009.02129.x
Epilepsia Harden CL, Meador KJ et. al.

Jun 9th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including antiepileptic drug (AED) teratogenicity and adverse perinatal outcomes. It is hig...

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Drugs  895 results see all →

Clinicaltrials.gov  12,765 results

Progressive myoclonic epilepsy: myoclonic epilepsy and ataxia due to KCNC1 mutation (ME...
https://doi.org/10.1684/epd.2020.1197
Epileptic Disorders : International Epilepsy Journal with Videotape; Barot N, Margiotta M et. al.

Sep 25th, 2020 - Progressive myoclonic epilepsy (PME) is characterized by prominent myoclonus and generalized or focal seizures. A recently described novel KCNC1 mutation is associated with a specific phenotype of progressive myoclonic epilepsy, which has been def...

Pharmacological treatment and SUDEP risk: A nationwide population-based case-control st...
https://doi.org/10.1212/WNL.0000000000010874
Neurology Sveinsson O, Andersson T et. al.

Sep 24th, 2020 - We conducted a nationwide case-control study in Sweden to test the hypothesis that antiepileptic drugs (AEDs), mono- polytherapy, adherence, antidepressants, neuroleptics, beta-blockers, and statins are associated with sudden unexpected death in e...

The Effect of Epilepsy and Antiepileptic Drugs on Cortical Motor Excitability in Patien...
https://doi.org/10.1097/WNF.0000000000000412
Clinical Neuropharmacology; Hamed SA, Tohamy AM et. al.

Sep 24th, 2020 - Transcranial magnetic stimulation (TMS) has been used to assess cortical disinhibition/excitation with epilepsy and determine the degree of patients' response to antiepileptic drugs (AEDs). However, the results of studies are variable and conflict...

A Novel Mouse Model for Pyridoxine-Dependent Epilepsy Due to Antiquitin Deficiency.
https://doi.org/10.1093/hmg/ddaa202
Human Molecular Genetics; Al-Shekaili HH, Petkau TL et. al.

Sep 24th, 2020 - Pyridoxine-dependent epilepsy (PDE) is a rare autosomal recessive disease caused by mutations in the ALDH7A1 gene leading to blockade of the lysine catabolism pathway. PDE is characterized by recurrent seizures that are resistant to conventional a...

Epilepsy syndromes, etiologies, and the use of next-generation sequencing in epilepsy p...
https://doi.org/10.1111/epi.16701
Epilepsia REFERENCES; Stödberg T, Tomson T et. al.

Sep 23rd, 2020 - Population-based data on epilepsy syndromes and etiologies in early onset epilepsy are scarce. The use of next-generation sequencing (NGS) has hitherto not been reported in this context. The aim of this study is to describe children with epilepsy ...

see more →

News  175 results

Antiepileptic drugs may not independently impair cognition
https://www.mdedge.com/jcomjournal/article/217306/epilepsy-seizures/antiepileptic-drugs-may-not-independently-impair/page/0/1?channel=258

Feb 13th, 2020 - Approximately 45% of patients were prescribed AED polypharmacy on admission, 25. 1% were prescribed AED monotherapy, and 29.

Outcomes of epilepsy surgery at 1 year may be better among older patients
https://www.mdedge.com/familymedicine/article/213808/epilepsy-seizures/outcomes-epilepsy-surgery-1-year-may-be-better-among?channel=39313
Clinical Neurology News; Erik Greb

Dec 8th, 2019 - BALTIMORE – Older patients may have better outcomes at 1 year after resective surgery for epilepsy than the general population does, according to research presented at the annual meeting of the American Epilepsy Society. A tendency toward greater.

Is serum serotonin level associated with risk of seizure-related breathing dysfunction?
https://www.mdedge.com/neurology/article/207435/epilepsy-seizures/serum-serotonin-level-associated-risk-seizure-related?channel=27970
Erik Greb

Sep 4th, 2019 - Significant increases in serum serotonin levels after seizures are associated with lower incidence of seizure-related breathing dysfunction in patients with epilepsy, according to research published online Sept. 4 in Neurology.

Cannabidiol reduces seizures in Dravet syndrome
https://www.mdedge.com/neurology/article/200390/epilepsy-seizures/cannabidiol-reduces-seizures-dravet-syndrome?channel=39313
Erik Greb

May 7th, 2019 - Philadelphia – Adjunctive cannabidiol (CBD) reduces seizure frequency in patients with Dravet syndrome, according to research presented at the annual meeting of the American Academy of Neurology. The two dosages in the study appear to have compara.

Population-level rate of SUDEP may have decreased
https://www.mdedge.com/jcomjournal/article/192550/epilepsy-seizures/population-level-rate-sudep-may-have-decreased
Erik Greb

Jan 11th, 2019 - NEW ORLEANS – The population-level rate of sudden unexpected death in epilepsy (SUDEP) may have decreased over time, according to data described at the annual meeting of the American Epilepsy Society. Whether this decrease resulted from an improve.

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Patient Education  29 results see all →