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About 53,888 results

ALLMedicine™ Migraine Center

Research & Reviews  23,013 results

Ketamine for Refractory Chronic Migraine: an Observational Pilot Study and Metabolite A...
https://doi.org/10.1002/jcph.1920
Journal of Clinical Pharmacology; Schwenk ES, Torjman MC et. al.

Jun 14th, 2021 - Patients with refractory chronic migraine have substantial disability and have failed many acute and preventive medications. When aggressive intravenous therapy is indicated, both lidocaine and (R,S)-ketamine infusions have been used successfully ...

Neuronal nitric oxide synthase regulates regional brain perfusion in healthy humans.
https://doi.org/10.1093/cvr/cvab155
Cardiovascular Research; O'Gallagher K, Puledda F et. al.

Jun 13th, 2021 - Neuronal nitric oxide synthase (nNOS) is highly expressed within the cardiovascular and nervous systems. Studies in genetically modified mice suggest roles in brain blood flow regulation while dysfunctional nNOS signalling is implicated in cerebro...

Migraine and neuroinflammation: the inflammasome perspective.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192049
The Journal of Headache and Pain; Kursun O, Yemisci M et. al.

Jun 11th, 2021 - Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory ...

Protein kinase C δ as a neuronal mechanism for headache in a chronic intermittent nitro...
https://doi.org/10.1097/j.pain.0000000000002353
Pain He Y, Shi Z et. al.

Jun 10th, 2021 - Migraine is one of the most common neurological disorders characterized by recurrent attacks of typically throbbing and unilateral headaches, affecting up to 20 % of the population worldwide. Despite the high prevalence and severity of this primar...

Ubrogepant: An Oral Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonist for Abor...
https://doi.org/10.1177/10600280211023810
The Annals of Pharmacotherapy; Nedd M, Garland S et. al.

Jun 10th, 2021 - To review the pharmacology, efficacy, and safety of ubrogepant as an abortive migraine treatment. A literature search of MEDLINE and PubMed was performed (January 2006 through May 2021) using the following search terms: ubrogepant, calcitonin gene...

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Guidelines  55 results

ACR Appropriateness Criteria® Cerebrovascular Disease-Child.
https://doi.org/10.1016/j.jacr.2020.01.036
Journal of the American College of Radiology : JACR; , Robertson RL et. al.

May 6th, 2020 - Stroke is an uncommon but an important and under-recognized cause of morbidity and mortality in children. Strokes may be due to either brain ischemia or intracranial hemorrhage. Common symptoms of pediatric acute stroke include headache, vomiting,...

Pharmacologic Acute and Preventive Treatment for Migraine in Children and Adolescents.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074018
JAMA Neurology; Szperka CL, VanderPluym JH et. al.

Dec 9th, 2019 - Pharmacologic Acute and Preventive Treatment for Migraine in Children and Adolescents.|2019|Szperka CL,VanderPluym JH,Oakley CB,|prevention & control,

Acupuncture for Pain
https://www.aafp.org/afp/2019/0715/p89.html
American Family Physician; Kelly,R.,et al

Jul 14th, 2019 - Acupuncture has been increasingly used as an integrative or complementary therapy for pain. It is well-tolerated with little risk of serious adverse effects. Traditional acupuncture and nontraditional techniques, such as electroacupuncture and dry...

Association Between Food Insecurity and Migraine Among US Young Adults
https://jamanetwork.com/journals/jamaneurology/article-abstract/2736340
JAMA Neurology; Nagata,J.,et al

Jun 23rd, 2019 - Food insecurity, defined as limited or intermittent access to nutritionally adequate and safe foods, accessed in socially acceptable ways, is associated with numerous adverse physical and mental health outcomes.1 One in 6 individuals are affected ...

Aids to management of headache disorders in primary care (2nd edition) : on behalf of t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734476
The Journal of Headache and Pain; Steiner TJ, Jensen R et. al.

May 22nd, 2019 - The Aids to Management are a product of the Global Campaign against Headache, a worldwide programme of action conducted in official relations with the World Health Organization. Developed in partnership with the European Headache Federation, they ...

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Drugs  1,241 results see all →

Clinicaltrials.gov  26,151 results

No Increased Risk of Hypertension With Erenumab?
https://www.medscape.com/viewarticle/953154

Jun 14th, 2021 - The migraine medication erenumab appears to pose no increased risk of hypertension, easing earlier concerns that this may be one of the drug's adverse events, an analysis of postmarketing data show. Nevertheless, investigators note that more resea...

Ubrogepant Effective for Acute Migraine
https://www.medscape.com/viewarticle/953095

Jun 14th, 2021 - Ubrogepant showed effectiveness for acute treatment of migraine when used with an anti–calcitonin gene-related peptide (CGRP) monoclonal antibody (mAb) preventive or with onabotulinumtoxinA (onabotA), or both, according to preliminary findings pre...

Moving More, Sitting Less Is Vital During Migraine
https://www.medscape.com/viewarticle/953097

Jun 14th, 2021 - People with migraine tend to have lower levels of physical activity than those without migraine despite the beneficial effects of physical activity on reducing frequency of migraine, according to a presentation at the American Headache Society's 2...

Migraine Linked to More COVID-19 Infections, Symptoms
https://www.medscape.com/viewarticle/953099

Jun 14th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Dr Robert Shapiro People with migraines appeared to have a higher likelihood of COVID-19 infection and subsequent symptoms of the disease, but the...

Ketamine for Refractory Chronic Migraine: an Observational Pilot Study and Metabolite A...
https://doi.org/10.1002/jcph.1920
Journal of Clinical Pharmacology; Schwenk ES, Torjman MC et. al.

Jun 14th, 2021 - Patients with refractory chronic migraine have substantial disability and have failed many acute and preventive medications. When aggressive intravenous therapy is indicated, both lidocaine and (R,S)-ketamine infusions have been used successfully ...

see more →

News  3,361 results

No Increased Risk of Hypertension With Erenumab?
https://www.medscape.com/viewarticle/953154

Jun 14th, 2021 - The migraine medication erenumab appears to pose no increased risk of hypertension, easing earlier concerns that this may be one of the drug's adverse events, an analysis of postmarketing data show. Nevertheless, investigators note that more resea...

Ubrogepant Effective for Acute Migraine
https://www.medscape.com/viewarticle/953095

Jun 14th, 2021 - Ubrogepant showed effectiveness for acute treatment of migraine when used with an anti–calcitonin gene-related peptide (CGRP) monoclonal antibody (mAb) preventive or with onabotulinumtoxinA (onabotA), or both, according to preliminary findings pre...

Moving More, Sitting Less Is Vital During Migraine
https://www.medscape.com/viewarticle/953097

Jun 14th, 2021 - People with migraine tend to have lower levels of physical activity than those without migraine despite the beneficial effects of physical activity on reducing frequency of migraine, according to a presentation at the American Headache Society's 2...

Migraine Linked to More COVID-19 Infections, Symptoms
https://www.medscape.com/viewarticle/953099

Jun 14th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Dr Robert Shapiro People with migraines appeared to have a higher likelihood of COVID-19 infection and subsequent symptoms of the disease, but the...

External Trigeminal Nerve Stimulation Passes At-Home Test
https://www.medscape.com/viewarticle/952893

Jun 9th, 2021 - A phase 3, sham-controlled clinical trial of an external trigeminal nerve stimulation (e-TNS) device showed confirmed superiority over a sham device and eliminated the most bothersome migraine symptoms after 2 hours of use. The study also demonstr...

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Patient Education  67 results see all →