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About 2,600 results

ALLMedicine™ Peripheral Neuropathy Center

Research & Reviews  821 results

Quantitative proteomic analysis of human peripheral nerves from subjects with type 2 di...
https://doi.org/10.1111/dme.14658
Diabetic Medicine : a Journal of the British Diabetic Ass... Ising E, Åhrman E et. al.

Jul 26th, 2021 - Diabetic peripheral neuropathy (DPN) is a common and severe complication to type 2 diabetes (T2D). The pathogenesis of DPN is not fully known, but several pathways and gene polymorphisms contributing to DPN are described. DPN can be studied using ...

Redox-sensitive TRP channels: A promising pharmacological target in chemotherapy-induce...
https://doi.org/10.1080/14728222.2021.1956464
Expert Opinion on Therapeutic Targets; Singh R, Adhya P et. al.

Jul 22nd, 2021 - Chemotherapy-induced peripheral neuropathy (CIPN) and its related pain is a major side effect of certain chemotherapeutic agents used in cancer treatment. Available analgesics are mostly symptomatic, and on prolonged treatment, patients become ref...

Diabetic Peripheral Neuropathy and Depression: Dancing with Wolves? - Mini-Review and C...
https://doi.org/10.1900/RDS.2021.17.17
The Review of Diabetic Studies : RDS; Vas PRJ, Papanas N

Jul 21st, 2021 - The co-existence of diabetic peripheral neuropathy (DPN) and depression in subjects with diabetes is being increasingly recognized. The interaction of these two serious comorbidities may increase morbidity and mortality. An emerging thought is tha...

ABCB1 Single Nucleotide Polymorphism Genotypes as Predictors of Paclitaxel-Induced Peri...
https://doi.org/10.1089/gtmb.2021.0014
Genetic Testing and Molecular Biomarkers; Abdelfattah NM, Solayman MH et. al.

Jul 19th, 2021 - Background: Paclitaxel is a key antineoplastic agent in the treatment of breast cancer and many other malignancies. However, paclitaxel-induced peripheral neuropathy (PIPN) is a common adverse event that occurs with paclitaxel therapy and frequent...

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Guidelines  1 results

Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of...
https://doi.org/10.1200/JCO.20.01399
Journal of Clinical Oncology : Official Journal of the Am... Loprinzi CL, Lacchetti C et. al.

Jul 14th, 2020 - To update the ASCO guideline on the recommended prevention and treatment approaches in the management of chemotherapy-induced peripheral neuropathy (CIPN) in adult cancer survivors. An Expert Panel conducted targeted systematic literature reviews ...

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Drugs  100 results see all →

Clinicaltrials.gov  56 results

A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)
https://clinicaltrials.gov/ct2/show/NCT03687970

Apr 15th, 2020 - The investigators propose that using the Diode Laser fiber type Selective Stimulator (DLss) in patients with chemotherapy-induced peripheral neuropathy (CIPN) will allow for the assessment of changes in small-fiber pain thresholds, to identify dif...

Preventive Treatment of Oxaliplatin Induced Peripheral Neuropathy in Metastatic Colorectal Cancer (POLAR-M)
https://clinicaltrials.gov/ct2/show/NCT03654729

Mar 26th, 2020 - Oxaliplatin, in combination with 5-fluorouracil plus folinate (or capecitabine), has increased survival in stage III colorectal cancer and prolonged life in stage IV patients, but its use is compromised because of severe toxicity. Chemotherapy-ind...

rTMS in Improving Neuropathy in Patients With Stage I-IV Cancer Who Have Received Oxaliplatin Chemotherapy
https://clinicaltrials.gov/ct2/show/NCT03219502

Mar 5th, 2020 - PRIMARY OBJECTIVES: I. Examine the effects of the repetitive transcranial magnetic stimulation (rTMS) training program on perceptions of chemotherapy-induced peripheral neuropathy (CIPN) versus placebo (PC) and wait-list control groups (WLC). SECO...

Lidocaine for Oxaliplatin-induced Neuropathy
https://clinicaltrials.gov/ct2/show/NCT03254394

Jan 21st, 2020 - Colorectal cancer is the third leading cause of cancer death in the United States, with an estimated incidence of 130.000 cases per year. Oxaliplatin is the first-line chemotherapy regimen for gastro-intestinal cancers. Despite its efficacy, oxali...

Reversing Diabetic Peripheral Neuropathy Through Exercise
https://clinicaltrials.gov/ct2/show/NCT03686423

Jan 20th, 2020 - This cross-over design study proposes an innovative multinuclear MRI approach to gain mechanistic insight into the exercise-associated adaptations in lower leg muscle function and peripheral nerve integrity of patients with diabetic peripheral neu...

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News  57 results

Chemo-Induced Neuropathy Linked With Low Hemoglobin, BMI, Age
https://www.medscape.com/viewarticle/946441

Feb 24th, 2021 - NEW YORK (Reuters Health) - Older patients with low hemoglobin and higher body mass index - particularly women - were more likely to experience chemotherapy-induced peripheral neuropathy (CIPN) in a cohort study. "The identification of these risk ...

Opioids Prescribed for Diabetic Neuropathy Pain, Against Advice
https://www.medscape.com/viewarticle/945830

Feb 14th, 2021 - Prescriptions for opioids as a first-line treatment for painful diabetic peripheral neuropathy (DPN) outnumbered those for other medications between 2014 and 2018, despite the fact that the former is not recommended, new research indicates. "We kn...

Diabetic Neuropathic Pain Linked to Brain Bioenergic Anomalies
https://www.medscape.com/viewarticle/939429

Oct 19th, 2020 - Abnormal mitochondrial activity in pain-processing areas of the brain may explain why some persons with type 2 diabetes experience painful peripheral neuropathy while others do not, new U.K. study findings have suggested. A greater ratio of adenos...

Diabetic Neuropathic Pain Linked to Brain Bioenergic Anomalies
https://www.staging.medscape.com/viewarticle/939429

Oct 19th, 2020 - Abnormal mitochondrial activity in pain-processing areas of the brain may explain why some persons with type 2 diabetes experience painful peripheral neuropathy while others do not, new U.K. study findings have suggested. A greater ratio of adenos...

Vitamin D Deficiency Linked to Painful Diabetic Neuropathy
https://www.medscape.com/viewarticle/932309

Jun 15th, 2020 - Takeaway This study suggests that vitamin D deficiency (<20 ng/mL) and insufficiency (<30 ng/mL) are associated with an increased risk of painful diabetic neuropathy (PDN). Why this matters Findings warrant a well-constructed clinical trial of vit...

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Patient Education  5 results see all →