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About 7,244 results

ALLMedicine™ Peripheral Neuropathy Center

Research & Reviews  3,217 results

Integrins protect sensory neurons in models of paclitaxel-induced peripheral sensory ne...
https://doi.org/10.1073/pnas.2006050118
Proceedings of the National Academy of Sciences of the Un... Shin GJ, Pero ME et. al.

Apr 20th, 2021 - Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect from cancer treatment with no known method for prevention or cure in clinics. CIPN often affects unmyelinated nociceptive sensory terminals. Despite the high prevalence, mole...

Inhibition of dual leucine zipper kinase prevents chemotherapy-induced peripheral neuro...
https://doi.org/10.1097/j.pain.0000000000002256
Pain Ma J, Goodwani S et. al.

Apr 19th, 2021 - Chemotherapy-induced peripheral neuropathy (CIPN) and chemotherapy-induced cognitive impairments (CICI) are common, often severe neurotoxic side effects of cancer treatment that greatly reduce quality of life of cancer patients and survivors. Curr...

Estrogen decline is a risk factor for paclitaxel-induced peripheral neuropathy: Clinica...
https://doi.org/10.1016/j.jphs.2021.03.001
Journal of Pharmacological Sciences; Miyamoto T, Hiramoto S et. al.

Apr 16th, 2021 - We performed clinical retrospective study in female cancer patients and fundamental experiments in mice, in order to clarify risk factors for paclitaxel-induced peripheral neuropathy (PIPN). In the clinical study, 131 of 189 female outpatients wit...

Downregulation of metallothionein-2 contributes to oxaliplatin-induced neuropathic pain.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045403
Journal of Neuroinflammation; Huang X, Deng J et. al.

Apr 14th, 2021 - We previously reported a correlation between small doses of oxaliplatin penetrating onto the spinal cord and acute pain after chemotherapy. Here, we propose that MT2 within the spinal dorsal horns participates in the development of oxaliplatin-ind...

Grip and load force control and coordination in individuals with diabetes in different ...
https://doi.org/10.1016/j.humov.2021.102793
Human Movement Science; Lima KCA, Santos GOC et. al.

Apr 12th, 2021 - The study aimed to investigate the control and coordination of grip force (normal component) and load force (tangential component) in three different manipulation tasks in individuals with diabetes with and with no diagnosis of diabetic peripheral...

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Guidelines  3 results

Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of...
https://doi.org/10.1200/JCO.20.01399
Journal of Clinical Oncology : Official Journal of the Am... Loprinzi CL, Lacchetti C et. al.

Jul 14th, 2020 - To update the ASCO guideline on the recommended prevention and treatment approaches in the management of chemotherapy-induced peripheral neuropathy (CIPN) in adult cancer survivors. An Expert Panel conducted targeted systematic literature reviews ...

Treatment of peripheral arterial disease in diabetes: a consensus of the Italian Societ...
https://doi.org/10.1016/j.numecd.2013.12.007
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Aiello A, Anichini R et. al.

Feb 3rd, 2014 - Diabetic foot (DF) is a chronic and highly disabling complication of diabetes. The prevalence of peripheral arterial disease (PAD) is high in diabetic patients and, associated or not with peripheral neuropathy (PN), can be found in 50% of cases of...

Painful diabetic peripheral neuropathy: consensus recommendations on diagnosis, assessm...
https://doi.org/10.1002/dmrr.1225
Diabetes/metabolism Research and Reviews; Tesfaye S, Vileikyte L et. al.

Jun 22nd, 2011 - Painful diabetic peripheral neuropathy (DPN) is common, is associated with significant reduction in quality of life and poses major treatment challenges to the practising physician. Although poor glucose control and cardiovascular risk factors hav...

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Drugs  289 results see all →

Clinicaltrials.gov  3,609 results

Integrins protect sensory neurons in models of paclitaxel-induced peripheral sensory ne...
https://doi.org/10.1073/pnas.2006050118
Proceedings of the National Academy of Sciences of the Un... Shin GJ, Pero ME et. al.

Apr 20th, 2021 - Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect from cancer treatment with no known method for prevention or cure in clinics. CIPN often affects unmyelinated nociceptive sensory terminals. Despite the high prevalence, mole...

Inhibition of dual leucine zipper kinase prevents chemotherapy-induced peripheral neuro...
https://doi.org/10.1097/j.pain.0000000000002256
Pain Ma J, Goodwani S et. al.

Apr 19th, 2021 - Chemotherapy-induced peripheral neuropathy (CIPN) and chemotherapy-induced cognitive impairments (CICI) are common, often severe neurotoxic side effects of cancer treatment that greatly reduce quality of life of cancer patients and survivors. Curr...

Estrogen decline is a risk factor for paclitaxel-induced peripheral neuropathy: Clinica...
https://doi.org/10.1016/j.jphs.2021.03.001
Journal of Pharmacological Sciences; Miyamoto T, Hiramoto S et. al.

Apr 16th, 2021 - We performed clinical retrospective study in female cancer patients and fundamental experiments in mice, in order to clarify risk factors for paclitaxel-induced peripheral neuropathy (PIPN). In the clinical study, 131 of 189 female outpatients wit...

Downregulation of metallothionein-2 contributes to oxaliplatin-induced neuropathic pain.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045403
Journal of Neuroinflammation; Huang X, Deng J et. al.

Apr 14th, 2021 - We previously reported a correlation between small doses of oxaliplatin penetrating onto the spinal cord and acute pain after chemotherapy. Here, we propose that MT2 within the spinal dorsal horns participates in the development of oxaliplatin-ind...

Pregabalin - pregabalin tablet, extended release-Sun Pharmaceutical Industries, Inc.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1ffa4233-c168-4d03-892b-d48051b55a0a

Apr 13th, 2021 -  Pregabalin extended-release tablets are indicated for the management of: •Neuropathic pain associated with diabetic peripheral neuropathy •Postherpetic neuralgia Efficacy of pregabalin extended-release tablets have not been established for the ma...

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News  121 results

Chemo-Induced Neuropathy Linked With Low Hemoglobin, BMI, Age
https://www.medscape.com/viewarticle/946441

Feb 24th, 2021 - NEW YORK (Reuters Health) - Older patients with low hemoglobin and higher body mass index - particularly women - were more likely to experience chemotherapy-induced peripheral neuropathy (CIPN) in a cohort study. "The identification of these risk ...

Opioids Prescribed for Diabetic Neuropathy Pain, Against Advice
https://www.medscape.com/viewarticle/945830

Feb 14th, 2021 - Prescriptions for opioids as a first-line treatment for painful diabetic peripheral neuropathy (DPN) outnumbered those for other medications between 2014 and 2018, despite the fact that the former is not recommended, new research indicates. "We kn...

Diabetic Neuropathic Pain Linked to Brain Bioenergic Anomalies
https://www.staging.medscape.com/viewarticle/939429

Oct 19th, 2020 - Abnormal mitochondrial activity in pain-processing areas of the brain may explain why some persons with type 2 diabetes experience painful peripheral neuropathy while others do not, new U.K. study findings have suggested. A greater ratio of adenos...

Diabetic Neuropathic Pain Linked to Brain Bioenergic Anomalies
https://www.medscape.com/viewarticle/939429

Oct 19th, 2020 - Abnormal mitochondrial activity in pain-processing areas of the brain may explain why some persons with type 2 diabetes experience painful peripheral neuropathy while others do not, new U.K. study findings have suggested. A greater ratio of adenos...

Vitamin D Deficiency Linked to Painful Diabetic Neuropathy
https://www.staging.medscape.com/viewarticle/932309

Jun 15th, 2020 - Takeaway This study suggests that vitamin D deficiency (<20 ng/mL) and insufficiency (<30 ng/mL) are associated with an increased risk of painful diabetic neuropathy (PDN). Why this matters Findings warrant a well-constructed clinical trial of vit...

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Patient Education  5 results see all →