About 2,725 results

ALLMedicine™ Trigeminal Neuralgia Center

Research & Reviews  988 results

The PATCH trial: efficacy and safety of 5% lidocaine-medicated plaster for the treatmen...
BMJ Open; Zhao C, Shrestha N et. al.

Aug 4th, 2021 - Trigeminal neuralgia (TN) is characterised by a sudden, severe, electric shock like paroxysmal pain, which is almost always associated with triggers. Carbamazepine is the first-line medical management of TN. However, side effects are common. Curre...

Microvascular Decompression for Trigeminal Neuralgia: A Prospective, Multicenter Study.
Neurosurgery Mizobuchi Y, Nagahiro S et. al.

Jul 30th, 2021 - Microvascular decompression (MVD) is the most effective procedure for the long-term management of trigeminal neuralgia (TGN). However, retrospective and single-center studies are inherently biased, and there are currently no prospective, multicent...

Using RNA-Seq to Explore the Hub Genes in the Trigeminal Root Entry Zone of Rats by Com...
Pain Physician; Tao R, Huang F et. al.

Jul 30th, 2021 - Mechanical compression on the trigeminal root entry zone (TREZ) by microvascular is the main etiology of primary trigeminal neuralgia (TN). To study the pathogenesis of TN, hub genes screening in the TREZ of TN in an animal model was performed. A ...

Efficacy and Safety of Awake CT-guided Percutaneous Balloon Compression of Trigeminal G...
Pain Medicine (Malden, Mass.); Huang B, Yao M et. al.

Jul 29th, 2021 - To describe the method and clinical efficacy of awake CT-guided percutaneous balloon compression (PBC) as a treatment for trigeminal neuralgia (TN). In this case-series, TN patients were treated with awake CT-guided PBC and followed for treatment ...

The thalamus in trigeminal neuralgia: structural and metabolic abnormalities, and influ...
BMC Neurology; Danyluk H, Andrews J et. al.

Jul 26th, 2021 - Medically-refractory trigeminal neuralgia (TN) can be treated successfully with operative intervention, but a significant proportion of patients are non-responders despite undergoing technically successful surgery. The thalamus is a key component ...

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Guidelines  3 results

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on Su...
Neurosurgery Hadjipanayis CG, Carlson ML et. al.

Jan 9th, 2018 - What surgical approaches for vestibular schwannomas (VS) are best for complete resection and facial nerve (FN) preservation when serviceable hearing is present? There is insufficient evidence to support the superiority of either the middle fossa (...

EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision.
European Journal of Neurology; Attal N, Cruccu G et. al.

Apr 21st, 2010 - This second European Federation of Neurological Societies Task Force aimed at updating the existing evidence about the pharmacological treatment of neuropathic pain since 2005. Studies were identified using the Cochrane Database and Medline. Trial...

1. Trigeminal neuralgia.
Pain Practice : the Official Journal of World Institute O... van Kleef M, van Genderen WE et. al.

Jul 22nd, 2009 - Trigeminal neuralgia is a common cause of facial pain. It has a significant impact on the quality of life and the socioeconomic functioning of the patient. The aim of this review is to provide recommendations for medical management of trigeminal n...

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Drugs  39 results see all →

Clinicaltrials.gov  28 results

Comparison Between Radiofrequency and Balloon Compression in the Treatment of Idiopathic Trigeminal Neuralgia

Feb 13th, 2020 - Patients diagnosed with idiopathic trigeminal neuralgia, refractory or intolerant to medical treatment, are randomly assigned (after signing a consent form), to receive one of two percutaneous procedures. The patients are evaluated a week before a...

Oxtellar Extended Release (Oxcarbazepine Extended Release) Patients With Trigeminal Neuralgia

Nov 1st, 2019 - Oxcarbazepine has been used off-label for TN for many years, but has a twice daily dosing. With the once daily dosing it should theoretically help with patient adherence and possibly decrease side effects, which is common with extended release for...

Regional Anesthesia in Refractory Trigeminal Neuralgia: 21 Cases Reported to the Limoges University Hospital

Sep 25th, 2019 - Trigeminal neuralgia is defined according to the third edition of the International Classification of Headache Disorders (ICHD-3) criteria. Chronic pain can have a major impact on the quality of life. First-line treatments are anti-epileptics, and...

Phenytoin as Treatment for Acute Exacerbations of Trigeminal Neuralgia - a Prospective Systematic Study of 20 Patients

Apr 25th, 2019 - The nature of trigeminal neuralgia (TN) is fluctuating and patients can experience periods of complete remission of pain as well as periods with excessive pain. TN is often triggered by innocuous intra- and extraoral stimuli such as chewing. Since...

Botulinum Toxin for Trigeminal Neuralgia

Nov 26th, 2018 - Trigeminal neuralgia (TN) is one of the most painful and common types of neuropathic pain encountered by clinicians. It is typically treated pharmacologically with anticonvulsants,but these can be ineffective, or can lose their effectiveness over ...

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News  25 results

Higher incidence of trigeminal neuralgia in patients with MS

Apr 2nd, 2020 - Key clinical point : The incidence of trigeminal neuralgia (TN) is 15-fold higher in patients with multiple sclerosis (MS) compared with the general neurological outpatient population. Major finding : Concomitant diagnoses of MS and TN were verifi.

Fast Five Quiz: Neuropathic Pain Management

Mar 27th, 2020 - Lesions or diseases of the somatosensory nervous system cause neuropathic pain. Instead of being used to sense touch, pressure, temperature, position, movement, and vibration, the patient perceives chronic or intermittent paresthesia and locally a...

Fast Five Quiz: Neuropathic Pain Management

Mar 27th, 2020 - Lesions or diseases of the somatosensory nervous system cause neuropathic pain. Instead of being used to sense touch, pressure, temperature, position, movement, and vibration, the patient perceives chronic or intermittent paresthesia and locally a...

Fast Five Quiz: Neuropathic Pain Management

Mar 27th, 2020 - Pharmacologic therapy is the first-line treatment for classic and idiopathic trigeminal neuralgia, with carbamazepine being the most well-studied treatment. Carbamazepine is an effective pain management treatment in patients with trigeminal neural...

New Guideline for Trigeminal Neuralgia Released

Jul 5th, 2019 - OSLO, Norway — All patients with trigeminal neuralgia (TN) should undergo MRI, a new guideline for diagnosing and treating this condition recommends. The guideline, developed by a task force of the European Academy of Neurology (EAN), also recomme...

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Patient Education  7 results see all →