About 110,265 results

ALLMedicine™ Dementia Center

Research & Reviews  36,349 results

Does APOE ɛ4 Status Change How 24-Hour Time-Use Composition Is Associated with Cognitiv...
Journal of Alzheimer's Disease : JAD; Dumuid D, Mellow ML et. al.

Jun 28th, 2022 - The 24 h time-use composition of physical activity, sedentary behavior, and sleep is linked to cognitive function in adults and may contribute to future dementia risk. However, the impact of reallocating time between behaviors may differ depending...

Understanding the Quality of Life Impacts of Providing Informal Care to People with Dem...
Journal of Alzheimer's Disease : JAD; Asfia SKBM, Bucholc J et. al.

Jun 28th, 2022 - There is currently a lack of a comprehensive review identifying the broad scope of factors that impact quality of life (QoL) of informal carers of people with dementia to validate existing measures and inform the provision of support services for ...

B Lymphocytes in Alzheimer's Disease-A Comprehensive Review.
Journal of Alzheimer's Disease : JAD; Plantone D, Pardini M et. al.

Jun 28th, 2022 - Alzheimer's disease (AD) represents the most common type of neurodegenerative dementia and is characterized by extracellular amyloid-β (Aβ) deposition, pathologic intracellular tau protein tangles, and neuronal loss. Increasing evidence has been a...

Prevalence of Depressive Symptoms in a Memory Clinic Cohort: A Retrospective Study.
Journal of Alzheimer's Disease : JAD; Loreto F, Fitzgerald A et. al.

Jun 28th, 2022 - Depression has been suggested to be a cause of reversible cognitive impairment but also a risk factor for neurodegenerative disease. Studies suggest that depression prevalence may be high in early onset dementia, particularly Alzheimer's disease, ...

Natural Pattern of Cognitive Aging.
Journal of Alzheimer's Disease : JAD; Novotný JS, Gonzalez-Rivas JP et. al.

Jun 28th, 2022 - Considering the world's rapidly increasing life expectancy, with people working and maintaining active lifestyles longer than ever before, addressing the effects of aging on cognition is of utmost importance. A greater understanding of cognitive a...

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Guidelines  35 results

The Effects of COVID-19 lockdown on neuropsychiatric symptoms in patients with dementia or mild cognitive impairment: A systematic review and meta-analysis
Psychogeriatrics Soysal P, Smith L et. al.

Feb 6th, 2022 - The COVID-19 pandemic may have a disproportionate impact on people with dementia/mild cognitive impairment (MCI) due to isolation and loss of services. The aim of this systematic review was to investigate the effects of the COVID-19 lockdown on ne...

International Practice Recommendations for the Recognition and Management of Hearing an...
Gerontology Littlejohn J, Bowen M et. al.

Jun 7th, 2021 - Hearing, vision, and cognitive impairment commonly co-occur in older people. However, the rate of recognition and appropriate management of combined hearing and vision impairment in people with dementia impairment is low. The aim of this work was ...

Medical Care of Adults With Down Syndrome: A Clinical Guideline.
JAMA Tsou AY, Bulova P et. al.

Oct 21st, 2020 - Down syndrome is the most common chromosomal condition, and average life expectancy has increased substantially, from 25 years in 1983 to 60 years in 2020. Despite the unique clinical comorbidities among adults with Down syndrome, there are no cli...

Recommendations of the 5th Canadian Consensus Conference on the diagnosis and treatment...
Alzheimer's & Dementia : the Journal of the Alzheimer's A... Ismail Z, Black SE et. al.

Jul 30th, 2020 - Since 1989, four Canadian Consensus Conferences on the Diagnosis and Treatment of Dementia (CCCDTD) have provided evidence-based dementia guidelines for Canadian clinicians and researchers. We present the results of the 5th CCCDTD, which convened ...

Hearing and Vision Impairment in People With Dementia: A Guide for Clinicians.
Archives of Physical Medicine and Rehabilitation; Leroi I, Constantinidou F et. al.

Jul 2nd, 2020 - Hearing and Vision Impairment in People With Dementia: A Guide for Clinicians.|2020|Leroi I,Constantinidou F,Langenbahn D,Heyn P,Yeung WK,|epidemiology,epidemiology,epidemiology,

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Drugs  350 results see all →

Clinicaltrials.gov  2,913 results

AAV2-GDNF for Advanced Parkinson s Disease

Jun 24th, 2022 - Objective: While medications can temporarily alleviate the symptoms of Parkinson s disease (PD), they do not influence the degenerative process. Progressive loss of nigral dopaminergic (DA) neurons (the pathological hallmark of PD) results in prog...

Genetic Characterization of Movement Disorders and Dementias

Jun 24th, 2022 - Objective The objective of this study is to ascertain individuals with a clinical diagnosis of a movement disorder or dementia, their affected and unaffected family members, and unrelated, healthy individuals (to provide control samples); to chara...

Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C

Jun 24th, 2022 - Niemann-Pick type C disease (NPC) is an autosomal recessive, lysosomal storage disorder characterized by accumulation of cholesterol and gangliosides. NPC is a rare (estimated prevalence of 1:120,000-150,000) neurodegenerative disorder with a wide...

Thinking and Memory Problems in People With HIV

Jun 24th, 2022 - The natural history of neurocognitive impairment in human immunodeficiency virus (HIV)-infected individuals remains poorly understood. While the advent of highly active antiretroviral therapy (HAART) has led to a decreased incidence of the most se...

Brain Inflammation and Function in Alcoholism

Jun 24th, 2022 - The abuse of high doses of alcohol is associated with cognitive impairment that in extreme cases can result in dementia. However, the mechanisms underlying the neurotoxic effects of alcohol to the human brain are poorly understood. Here we test th...

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News  4,397 results

Fit Kids More Likely to Stay Mentally Sharp With Age

Jun 27th, 2022 - You know physical activity helps kids build strong muscles and bones, and lowers the risk of things like heart disease and diabetes later in life. Now researchers from Australia reveal another reason to encourage your child to move: It may help th...

Sleep Tied to Objective and Subjective Cognition

Jun 23rd, 2022 - Amy Costa Poor objective sleep efficiency may contribute to older adults overestimating their cognitive abilities, preliminary findings from a pilot study of objective and subjective cognitive measures have shown. The pilot study underscored the i...

Can a Single Brain Scan Accurately Diagnose Alzheimer's?

Jun 21st, 2022 - Updated June 22, 2022 // Editor's note: This story has been updated with comments from Dr Rebecca Edelmayer of the Alzheimer's Association. A machine learning algorithm can determine whether an individual has Alzheimer's disease (AD) based on a si...

FDA Panel Rejects Pimavanserin for Alzheimer's Psychosis

Jun 17th, 2022 - A US Food and Drug Administration (FDA) advisory panel has rejected the atypical antipsychotic pimavanserin (Nuplazid, Acadia Pharmaceuticals) for the treatment of Alzheimer's disease psychosis (ADP). In a 9-3 vote, the Psychopharmacologic Drugs A...

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Patient Education  62 results see all →