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About 1,388 results

ALLMedicine™ Intracranial Tumors Center

Research & Reviews  536 results

Gamma knife radiosurgery for trigeminal schwannomas: A systematic review and meta-analy...
https://doi.org/10.1016/j.jocn.2022.05.001
Journal of Clinical Neuroscience : Official Journal of Th... Yang S, Wang J et. al.

May 14th, 2022 - Gamma knife radiosurgery (GKRS) has been deemed as the gold standard stereotactic radiosurgery (SRS) mode for the treatment of intracranial tumors, cerebrovascular diseases and brain functional diseases. Our study was aimed to systematically evalu...

Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabi...
https://doi.org/10.1038/s41588-022-01061-8 10.3171/2015.6.JNS15591 10.1016/j.celrep.2018.03.013 10.1016/S1470-2045(17)30155-9 10.1007/s00401-017-1678-x 10.1093/neuonc/noz061 10.1038/ncomms14433 10.1038/s41586-021-03850-3 10.1093/bioinformatics/btu049 10.1186/1750-1172-4-16 10.1126/science.1233009 10.1038/ng.2526 10.1038/s41467-017-00174-7 10.1007/s00401-017-1715-9 10.1007/s00401-013-1093-x 10.1007/s00401-013-1187-5 10.1186/s40478-020-00994-7 10.1083/jcb.200703010 10.1083/jcb.201503081 10.1016/j.cell.2010.01.029 10.1038/s41467-020-18582-7 10.1227/00006123-199009000-00008 10.1016/j.cell.2014.09.029 10.1038/s41592-018-0048-5 10.3171/jns.1995.82.5.0864 10.1016/j.cell.2017.03.022 10.1016/S0021-9258(19)47378-X 10.1016/S0021-9258(18)31504-7 10.1128/MCB.00146-10 10.1172/JCI96636 10.1186/s13059-017-1349-1 10.1093/bioinformatics/bty011 10.1093/bioinformatics/bty316 10.1016/j.cell.2017.10.001 10.1038/s41587-019-0114-2 10.1038/s41467-018-03959-6 10.1002/jcp.20106 10.1101/gad.303776.117 10.1016/j.matbio.2010.08.001 10.1038/nature14432 10.1084/jem.20170391 10.1038/s41586-019-1419-5 10.1038/s41422-020-0287-8 10.1016/j.cell.2020.12.040 10.1083/jcb.144.4.789 10.1186/1742-2094-9-77 10.1093/emboj/21.7.1505 10.1007/s00401-016-1545-1 10.3171/2014.7.JNS131644 10.1007/s00401-019-02008-w 10.1093/neuros/nyaa355 10.1158/1541-7786.MCR-11-0559 10.1158/2159-8290.CD-20-0160 10.1038/ng.3651 10.1007/s00401-019-02095-9 10.1186/s40478-020-01040-2 10.1093/neuonc/noaa226 10.1093/jnci/djv377 10.1093/neuonc/noy104 10.1093/neuonc/nox094 10.1007/s11060-019-03333-6 10.1038/s41586-020-03064-z 10.1038/s41586-020-03114-6 10.1038/s41586-020-03133-3 10.1007/s00401-020-02188-w 10.1038/nm0795-686 10.1016/j.ccell.2018.11.009 10.1093/neuonc/noz175.583 10.1093/neuonc/noab118 10.1038/onc.2009.416 10.1186/s13059-014-0503-2 10.1186/s13059-016-1066-1 10.1038/nature26000 10.1093/bioinformatics/btu170 10.1101/gr.213611.116 10.1038/s41587-019-0201-4 10.1093/bioinformatics/btt656 10.1038/labinvest.3700307 10.1016/j.cell.2016.11.048 10.7554/eLife.19760 10.1038/nbt.4096 10.1016/j.cell.2019.05.031 10.1186/s13059-019-1874-1 10.1038/s41592-019-0619-0
Nature Genetics; Choudhury A, Magill ST et. al.

May 10th, 2022 - Meningiomas are the most common primary intracranial tumors. There are no effective medical therapies for meningioma patients, and new treatments have been encumbered by limited understanding of meningioma biology. Here, we use DNA methylation pro...

Multiple recurrences of unknown primary tumor in a meningioma: A case report.
https://doi.org/10.1177/19714009221096836
The Neuroradiology Journal; Essibayi MA, Abdallah A et. al.

Apr 30th, 2022 - Metastasis of a systemic tumor into a primary brain tumor has been rarely reported in the literature. These metastases could be seen mostly in meningiomas and in less frequently in the other intracranial tumors. Carcinoma of an unknown primary sit...

A Rare Case of an Intracranial Dermoid Cyst with Atypical Appearance on Computed Tomogr...
https://doi.org/10.12659/AJCR.935115
The American Journal of Case Reports; Delgado-Muñoz P, Oliver-Ricart MS et. al.

Apr 24th, 2022 - BACKGROUND Dermoid cysts are rare benign intracranial tumors that usually present classic computed tomography (CT) and magnetic resonance imaging (MRI) characteristics, allowing for relatively simple diagnostic confirmation. Atypical imaging featu...

Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAFV600E /NRASQ61K ...
https://doi.org/10.1002/mc.23407
Molecular Carcinogenesis; Jandova J, Park SL et. al.

Apr 14th, 2022 - Molecularly targeted therapeutics have revolutionized the treatment of BRAFV600E -driven malignant melanoma, but the rapid development of resistance to BRAF kinase inhibitors (BRAFi) presents a significant obstacle. The use of clinical antimalaria...

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Clinicaltrials.gov  8 results

Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma
https://clinicaltrials.gov/ct2/show/NCT01345136

Mar 4th, 2022 - This protocol is a Phase II, open-label, efficacy and safety study of single-agent RAD001 in patients with NF2. During the study, subjects will receive continuous daily oral treatment with RAD001 for up to 1 year or until tumor progression. Primar...

SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON)
https://clinicaltrials.gov/ct2/show/NCT05254197

Feb 24th, 2022 - Non-malignant central nervous system (CNS) tumor accounts for 70% of all primary CNS tumors, and over 300,000 patients were diagnosed with non-malignant CNS tumor per year in the United States. Not much is known about the natural history of non-ma...

Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas
https://clinicaltrials.gov/ct2/show/NCT04659421

Feb 11th, 2022 - Low-grade gliomas (LGGs) are the most common intracranial tumors in children, accounting for about 40% of intracranial tumors in children. The biological characteristics and clinical prognosis of LGGs vary greatly, and they can present different b...

[18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers
https://clinicaltrials.gov/ct2/show/NCT03539731

Sep 10th, 2021 - PRIMARY OBJECTIVES: I. Determine whether the fluorine F 18 DASA-23 ([18F]DASA 23) PET scan signal change from pre-therapy to one week after initiation of therapy can predict the tumor's responsiveness to therapy and 6 month progression free surviv...

Exploratory Study of PD-1 Neoadjuvant Treatment of Recurrent Meningioma
https://clinicaltrials.gov/ct2/show/NCT04728568

Aug 10th, 2021 - Meningioma is one of the most common primary intracranial tumors, accounting for 13% to 26% of all intracranial tumors. Although most meningiomas are benign tumors and can be cured by surgical resection, more than 20% of WHO II (atypical) and abou...

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News  11 results

Making Progress Against the Blood-Brain Barrier
https://www.onclive.com/view/making-progress-against-the-blood-brain-barrier

Jan 31st, 2022 - Primary and metastatic brain tumors present a significant therapeutic challenge, in large part because they are protected by the blood-brain barrier (BBB), a highly restrictive interface between the bloodstream and the brain that prevents most dru...

'Phantom Odors' a Common but Under-Reported Toxicity of Radiation Therapy
https://www.medscape.com/viewarticle/961865

Nov 1st, 2021 - NEW YORK (Reuters Health) - Patients who undergo proton-beam radiation therapy to tumors located in or adjacent to the olfactory region may develop phantosmia - the perception of a foul-smelling odor for which there is no external stimulus. "Phant...

Advanced 3D MRI Technology Marks a Leap Forward in Glioblastoma Imaging
https://www.onclive.com/view/advanced-3d-mri-technology-marks-a-leap-forward-in-glioblastoma-imaging

Oct 6th, 2021 - Hui-Kuo Shu, MD, PhD Associate Professor Although advances have been made in imaging techniques for patients with glioblastoma multiforme (GBM), new tools are needed to supplement standard imaging sequences. Researchers at the Winship Cancer...

The Man Behind the Brain: Harvey Cushing's Legacy
https://www.staging.medscape.com/viewarticle/936873

Sep 9th, 2020 - A physician is obligated to consider more than a diseased organ, more than even the whole man — he must view the man in his world. –Harvey Williams Cushing A well-known photo of Harvey Cushing, taken by a friend in Switzerland. Source: Wikimedia C...

ASCO VTE guideline update: DOACs now an option for prevention, treatment
https://www.mdedge.com/fedprac/avaho/article/206647/thrombosis/asco-vte-guideline-update-doacs-now-option-prevention/page/0/1?channel=263

Aug 19th, 2019 - Additional updates CNS metastases. The anticoagulation recommendations were also updated to include patients with metastatic central nervous system malignancies (those with primary CNS malignancies were included previously).

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