ALLMedicine™ Movement Disorders Center

Mar 25th, 2023 - In late-life depression (LLD), several differences between patients whose first episode is reported after age 65 (late-onset depression, LOD) and those with early-onset depression (EOD) might reflect the effects of brain ageing. To test this hypot...

Mar 25th, 2023 - Tremor is the most frequent human movement disorder, and its diagnosis is based on clinical assessment. Yet finding the accurate clinical diagnosis is not always straightforward. Fine-tuning of clinical diagnostic criteria over the past few decade...

Mar 23rd, 2023 - Substantia nigra (SN) free water has been suggested as a good surrogate marker in Parkinson's disease (PD). However, its usefulness for diagnosing prodromal PD (pPD) and monitoring disease progression warrants further validation. The aim was to in...

Mar 23rd, 2023 - Magnetic resonance-guided focused-ultrasound (MRgFUS) thalamotomy is an effective treatment for essential and other tremors. It targets the ventrointermedius (Vim) nucleus, which is the thalamic relay in a proprioceptive pathway, and contains kine...

Mar 22nd, 2023 - FOXG1 syndrome is a rare neurodevelopmental disorder associated with severe cognitive dysfunction, autistic behavior, and early-onset hyperkinetic movement disorders. Patients have also been reported to experience sleep disturbances. However, thes...

Dec 30th, 2020 - Most patients with movement disorders have speech impairments resulting from sensorimotor abnormalities that affect phonatory, articulatory, and prosodic speech subsystems. There is widespread cross-discipline use of speech recordings for diagnost...

May 7th, 2020 - Movement disorders and neurodegenerative diseases are a variety of conditions that involve progressive neuronal degeneration, injury, or death. Establishing the correct diagnosis of a movement disorder or neurodegenerative process can be difficult...

Jan 15th, 2008 - Dementia and movement disorders.|2008|Dormont D,Seidenwurm DJ, , ,|classification,complications,diagnosis,standards,classification,complications,diagnosis,

Mar 21st, 2023 - Objectives The purpose of this protocol is to improve understanding of the pathophysiology of movement disorders by performing small behavioral, electrophysiological and neuroimaging sub-studies. This will allow identifying dysfunction of the cent...

Mar 10th, 2023 - Study Description: The purpose of this protocol is to investigate efficacy of intermittent theta burst stimulation (iTBS) targeting the left dorsolateral prefrontal cortex (DLPFC) in patients with functional movement disorders (FMD). Participants ...

Mar 10th, 2023 - Study Description: This randomized crossover trial will determine whether 12 weeks of overground gait training with a robotic exoskeleton outside of the clinical setting has a beneficial effect on walking ability, muscle activity, and overall gros...

Mar 9th, 2023 - Objective The purposes of this protocol are: To provide DBS therapy and follow-up management To maintain a cohort of patients treated with DBS who can participate in other NIH protocols addressing the efficacy of functional surgery and the relevan...

Mar 9th, 2023 - Many of the recognized intrinsic factors for falls are commonly seen in ALS, including advanced age, muscle weakness, gait and balance problems, and previous falls. The American Academy of Neurology ALS Quality Standards Committee recommends query...

Mar 7th, 2023 - Regular distressing dreams during childhood were significantly associated with higher risks of developing cognitive impairment or Parkinson's disease by age 50. (eClinicalMedicine) Alzheimer's blood biomarkers of phosphorylated tau and amyloid bet...

Feb 22nd, 2023 - Unilateral focused ultrasound ablation targeted to the globus pallidus internus led to a higher percentage of Parkinson's disease patients with improved motor function or reduced dyskinesia compared with sham over 3 months but was associated with ...

Jan 17th, 2023 - Ecopipam, in development for Tourette syndrome in children and adolescents, has shown in a randomized, controlled trial that, compared with placebo, it reduced tics and reduced the risk for some of the common side effects of other treatments, incl.

Nov 22nd, 2022 - New seizures or epilepsy diagnoses among people who had COVID in 2020 and early 2021 were low overall after infection, but higher than in people with influenza. (Neurology) Neuroimmune proteins can differentiate between tauopathies like Alzheimer'...

Nov 11th, 2022 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook.  The potentia...