×
About 56,168 results

ALLMedicine™ Seizures Center

Research & Reviews  17,862 results

Phenotypic spectrum and long-term outcome of children with genetic early-infantile-onse...
https://doi.org/10.1684/epd.2021.1394
Epileptic Disorders : International Epilepsy Journal With... Hu C, Liu D et. al.

Dec 4th, 2021 - Developmental and epileptic encephalopathy (DEE) is characterized by refractory seizures, developmental delay or intellectual disability, which may be caused by gene mutation. In this study, we explored the clinical phenotype and long-term outcome...

Electroclinical features and long-term therapeutic response in patients with typical ab...
https://doi.org/10.1684/epd.2021.1392
Epileptic Disorders : International Epilepsy Journal With... Vlachou M, Skrimpas GA et. al.

Dec 4th, 2021 - To characterize in detail the electroclinical features of typical absence seizures and elucidate whether EEG or semiology features, alone or in combination, can predict long-term therapeutic outcome. We analysed video-EEG recordings from 213 typic...

Apoptosis in the Dentate Nucleus Following Kindling-induced Seizures in Rats.
https://doi.org/10.2174/1871527320666211201161800
CNS & Neurological Disorders Drug Targets; Taddei E, Rosiles A et. al.

Dec 3rd, 2021 - Epilepsy is a common neurological disorder characterized by abnormal and recurrent neuronal discharges that result in epileptic seizures. The dentate nuclei of the cerebellum receive excitatory input from different brain regions. Purkinje cell los...

Risk of seizure recurrence in people with single seizures and early epilepsy - Model de...
https://doi.org/10.1016/j.seizure.2021.11.007
Seizure Bonnett LJ, Kim L et. al.

Dec 3rd, 2021 - Following a single seizure, or recent epilepsy diagnosis, it is difficult to balance risk of medication side effects with the potential to prevent seizure recurrence. A prediction model was developed and validated enabling risk stratification whic...

A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalizat...
https://clinicaltrials.gov/ct2/show/NCT04252846

Dec 3rd, 2021 - The primary purpose of this study is to assess the retention rate of perampanel as a reliable proxy for overall effectiveness and tolerability in participants aged at least 12 years who are prescribed perampanel (for partial onset seizures [POS] w...

see more →

Guidelines  20 results

ACR Appropriateness Criteria® Seizures-Child.
https://doi.org/10.1016/j.jacr.2021.02.020
Journal of the American College of Radiology : JACR; , Trofimova A et. al.

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

ACR Appropriateness Criteria® Cerebrovascular Disease-Child.
https://doi.org/10.1016/j.jacr.2020.01.036
Journal of the American College of Radiology : JACR; , Robertson RL et. al.

May 7th, 2020 - Stroke is an uncommon but an important and under-recognized cause of morbidity and mortality in children. Strokes may be due to either brain ischemia or intracranial hemorrhage. Common symptoms of pediatric acute stroke include headache, vomiting,...

ACR Appropriateness Criteria® Seizures and Epilepsy.
https://doi.org/10.1016/j.jacr.2020.01.037
Journal of the American College of Radiology : JACR; , Lee RK et. al.

May 7th, 2020 - Seizures and epilepsy are a set of conditions that can be challenging to diagnose, treat, and manage. This document summarizes recommendations for imaging in different clinical scenarios for a patient presenting with seizures and epilepsy. MRI of ...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005755
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

SEOM clinical guidelines for diagnosis and treatment of glioblastoma (2017).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785619
Clinical & Translational Oncology : Official Publication ... Martínez-Garcia M, Álvarez-Linera J et. al.

Nov 1st, 2017 - Glioblastoma (GB) is the most common brain malignancy and accounts for over 50% of all high-grade gliomas. Radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) chemotherapy is the current standard of care for patients with newly diag...

see more →

Drugs  1,990 results see all →

Clinicaltrials.gov  479 results

A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalizat...
https://clinicaltrials.gov/ct2/show/NCT04252846

Dec 3rd, 2021 - The primary purpose of this study is to assess the retention rate of perampanel as a reliable proxy for overall effectiveness and tolerability in participants aged at least 12 years who are prescribed perampanel (for partial onset seizures [POS] w...

Energy Expenditure and Quality of Life in Epilepsy
https://clinicaltrials.gov/ct2/show/NCT04546711

Dec 1st, 2021 - The ketogenic diet (KD) is a high fat, very low carbohydrate diet that promotes a variety of changes in the chemical processes on the body associated with reduced frequency and severity of seizures in patients with epilepsy. The reasons for this i...

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy
https://clinicaltrials.gov/ct2/show/NCT03739840

Nov 30th, 2021 - The purpose of the study is to evaluate the efficacy, safety and tolerability of the 3 selected dose regimens of padsevonil (PSL) administered concomitantly with up to 3 anti-epileptic drugs (AEDs) compared with placebo for treatment of observable...

Measuring sVAP-1 as a Predictor of Pregnancy Problems
https://clinicaltrials.gov/ct2/show/NCT04891315

Nov 30th, 2021 - Pre-eclampsia is a common pregnancy disorder defined as high blood pressure and protein in the urine after 20 weeks of pregnancy. It affects the function of the placenta and can cause severe complications, e.g, stroke, multiple organ damage and se...

A Study to Test the Safety/ Efficacy of Brivaracetam (BRV) Used as Adjunctive Treatment in Subjects >=16 Years of Age With Partial Seizures With or Without Secondary Generalization
https://clinicaltrials.gov/ct2/show/NCT03250377

Nov 12th, 2021 - The purpose of the study is to evaluate the long-term safety and tolerability of Brivaracetam (BRV) in focal epilepsy subjects with partial seizures and to evaluate the maintenance of efficacy of BRV over time.

see more →

News  1,943 results

Alzheimer's Plasma Exchange; Fish Intake and Brain Health; HIV Neuropathy
https://www.medpagetoday.com/neurology/generalneurology/95543

Nov 9th, 2021 - People with mild Alzheimer's disease who received plasma exchange with albumin replacement showed improvement in memory, language abilities, processing speed, and quality of life, AMBAR trial data showed. (Alzheimer's & Dementia) Fewer people trea...

Common Diabetes Drug Shrinks Brain Tumors in Mice
https://www.medscape.com/viewarticle/962161

Nov 3rd, 2021 - Many cancers with known genetic causes can be treated by targeting tumors and leaving healthy cells unscathed. But that's not the case for a rare type of brain and spinal cord cancer that primarily strikes children and has no obvious genetic cause...

Managing Simple Febrile Seizures Without Lumbar Puncture Safe: 15-Year Study
https://www.medscape.com/viewarticle/962096

Nov 2nd, 2021 - Most children with simple febrile seizures (SFSs) can be safely managed without lumbar puncture or other diagnostic tests without risking delayed diagnosis of bacterial meningitis, new data gathered from a 15-year span suggest. Vidya R. Raghavan, ...

Seizures Tied to a Doubling of Dementia Risk in Young Survivors
https://www.medscape.com/viewarticle/961582

Oct 26th, 2021 - Patients younger than 60 years who have stroke and then experience seizures have a significantly increased risk for dementia, new research shows. Results of a large study show that young stroke survivors who subsequently developed seizures had a t...

Avoidant attachment style may drive mood in movement disorders
https://www.mdedge.com/psychiatry/article/247468/movement-disorders/avoidant-attachment-style-may-drive-mood-movement
Heidi Splete

Oct 15th, 2021 - Patients with functional neurological disorders demonstrate higher levels of depression and alexithymia – in addition to signs of an avoidant attachment style – compared with those with other neurological disorders and healthy controls, investigat.

see more →

Patient Education  173 results see all →