About 70,300 results

ALLMedicine™ Seizures Center

Research & Reviews  21,677 results

Generalized Scarring and Oral Ulcers in a Child-A Diagnostic Dilemma.
Skinmed Mendiratta V, Samudrala S

Jul 3rd, 2022 - A 5-year-old girl, the first-born child from a nonconsanguineous marriage, presented with multiple clear fluid-filled lesions present for 2 years, covering the body and when ruptured healed spontaneously with scarring. Sunlight aggravated the lesi...

Higher susceptibility to 6 Hz corneal kindling and lower responsiveness to antiseizure ...
Epilepsia Vande Vyver M, Barker-Haliski M et. al.

Jul 2nd, 2022 - Epileptic spikes and seizures seem present early in the disease process of Alzheimer's disease (AD). However, it is unclear how soluble and insoluble amyloid beta (Aβ) and tau proteins affect seizure development in vivo. We aim to contribute to th...

Neuronal subset-specific phosphatase and tensin homolog knockout mice exhibit age and b...
Neuroreport Narvaiz DA, Sullens DG et. al.

Jul 2nd, 2022 - Seizures induce brain region-dependent enhancements in microglia/macrophage activation. Neuronal subset-specific phosphatase and tensin homolog (PTEN) knockout (KO) mice display hyperactive mammalian target of rapamycin (mTOR) signaling in the hip...

Monitoring of adverse events in recipients of the 2-dose Ebola vaccine regimen of Ad26....
The Journal of Infectious Diseases; Nyombayire J, Ingabire R et. al.

Jul 2nd, 2022 - From 2019-2021, Rwandan residents of the border with Democratic Republic of the Congo were offered the Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen. Non-pregnant ≥2 years-olds were eligible. Unsolicited adverse events (UAE) were reported through ...

Distributed source localization of epileptiform discharges in juvenile myoclonic epilep...
Medicine Kim KY, Moon JU et. al.

Jul 2nd, 2022 - Juvenile myoclonic epilepsy (JME) is a common generalized epilepsy syndrome considered the prototype of idiopathic generalized epilepsy. To date, generalized and focal seizures have been the fundamental concepts for classifying seizure types. In s...

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Guidelines  21 results

Minimum standards for inpatient long-term video-electroencephalographic monitoring: A c...
Epilepsia Tatum WO, Mani J et. al.

Dec 14th, 2021 - The objective of this clinical practice guideline is to provide recommendations on the indications and minimum standards for inpatient long-term video-electroencephalographic monitoring (LTVEM). The Working Group of the International League Agains...

ACR Appropriateness Criteria® Seizures-Child.
Journal of the American College of Radiology : JACR; , Trofimova A et. al.

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

ACR Appropriateness Criteria® Cerebrovascular Disease-Child.
Journal of the American College of Radiology : JACR; , Robertson RL et. al.

May 7th, 2020 - Stroke is an uncommon but an important and under-recognized cause of morbidity and mortality in children. Strokes may be due to either brain ischemia or intracranial hemorrhage. Common symptoms of pediatric acute stroke include headache, vomiting,...

ACR Appropriateness Criteria® Seizures and Epilepsy.
Journal of the American College of Radiology : JACR; , Lee RK et. al.

May 7th, 2020 - Seizures and epilepsy are a set of conditions that can be challenging to diagnose, treat, and manage. This document summarizes recommendations for imaging in different clinical scenarios for a patient presenting with seizures and epilepsy. MRI of ...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

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Drugs  2,207 results see all →

Clinicaltrials.gov  1,475 results

Tumor Related Epilepsy

Jul 1st, 2022 - Objective This protocol is being performed to 1) study the natural history and disease pathogenesis in patients with tumor related epilepsy, 2) collect prospective data on seizure outcomes following standard surgical treatment of brain tumors with...

Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C

Jul 1st, 2022 - Niemann-Pick type C disease (NPC) is an autosomal recessive, lysosomal storage disorder characterized by accumulation of cholesterol and gangliosides. NPC is a rare (estimated prevalence of 1:120,000-150,000) neurodegenerative disorder with a wide...

Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia

Jul 1st, 2022 - Propionic acidemia (PA) is one of the most common inborn errors of organic acid metabolism. Although this disorder is now routinely detected in the immediate neonatal period on the US newborn screen, clinical outcomes are poor despite timely and a...

A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy

Jul 1st, 2022 - The purpose of the study is to evaluate the efficacy of brivaracetam (BRV) compared to placebo (PBO) as adjunctive treatment in subjects (>=16 to 80 years of age) with partial seizures with or without secondary generalization despite current treat...

Mothers' Thoughts About Kids and Eating

Jul 1st, 2022 - Purpose This study will investigate the impact of health information on choices that parents make about food for their children. Participants will use a virtual reality model of a buffet to make food choices. Mothers and fathers with a biological ...

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News  2,593 results

Severe ipsilateral headache

Jun 14th, 2022 - On the basis of the patient's presentation, family history, and personal history of headache, she seems to be presenting with hemiplegic migraine, an uncommon migraine subtype characterized by recurrent headaches associated with temporary unilater.

Frustrated With Delays, Doctors Take Aim at Prior Authorization

May 26th, 2022 - Last December, a young patient was admitted to Nationwide Children's Hospital in Columbus, Ohio, after several medications had failed to quell the child's relentless seizures. A hospital pediatrician, Vignesh Doraiswamy, consulted with neurologist...

Downtime? Enjoy it
Allan M. Block, MD

May 23rd, 2022 - Everything in medicine, and pretty much the universe, is based on averages. Average reduction of seizures, average blood levels, average response to treatment, average insurance reimbursement, average time spent with a new consult.

Phase 3 Data on Fenfluramine for Lennox-Gastaut Published

May 5th, 2022 - A daily dose of fenfluramine (Fintepla, UCB), when added to an existing anti-epileptic treatment regimen, significantly reduced the frequency of drop seizures associated with Lennox-Gastaut syndrome (LGS) in the phase 3 study that led to US approv...

Air Pollution a Seizure Trigger for Patients With Epilepsy

May 2nd, 2022 - Elevated concentrations of carbon monoxide (CO) due to air pollution increases the risk of epileptic seizures, a unique new study suggests. The link between daily outdoor CO exposure and seizure risk was particularly evident for subclinical seizur...

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Patient Education  147 results see all →