About 78,368 results

ALLMedicine™ Seizures Center

Research & Reviews  23,765 results

Brain lesion locations associated with secondary seizure generalization in tumors and s...
Human Brain Mapping; Nordberg J, Schaper FLWVJ et. al.

Mar 28th, 2023 - Structural brain lesions are the most common cause of adult-onset epilepsy. The lesion location may contribute to the risk for epileptogenesis, but whether specific lesion locations are associated with a risk for secondary seizure generalization f...

Metabolic phenotyping of pilomotor seizures in autoimmune encephalitis.
CNS Neuroscience & Therapeutics; Sun Y, Zhao X et. al.

Mar 28th, 2023 - Ictal piloerection (IP) is an uncommon symptom in focal epilepsy and is associated with autoimmune encephalitis (AE). However, the networks involved in AE-associated IP are still unclear. To have a better understanding of IP underlying mechanisms,...

Spectrum of motor responses elicited by electrical stimulation of primary motor cortex:...
Epilepsy & Behavior : E&B; Fotedar N, Fernandez-BacaVaca G et. al.

Mar 27th, 2023 - To study the neurophysiology of motor responses elicited by electrical stimulation of the primary motor cortex. We studied motor responses in four patients undergoing invasive epilepsy monitoring and functional cortical mapping via electrical cort...

Consensus recommendations on Epilepsy in Phelan-McDermid syndrome.
European Journal of Medical Genetics; de Coo IFM, Jesse S et. al.

Mar 27th, 2023 - Phelan-McDermid syndrome (PMS) is a 22q13.3 deletion syndrome that presents with a disturbed development, neurological and psychiatric characteristics, and sometimes other comorbidities like seizures. The epilepsy manifests itself in a variety of ...

Ligand-gated mechanisms leading to ictogenesis in focal epileptic disorders.
Neurobiology of Disease; Avoli M, Chen LY et. al.

Mar 27th, 2023 - We review here the neuronal mechanisms that cause seizures in focal epileptic disorders and, specifically, those involving limbic structures that are known to be implicated in human mesial temporal lobe epilepsy. In both epileptic patients and ani...

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Guidelines  22 results

Minimum standards for inpatient long-term video-electroencephalographic monitoring: A c...
Epilepsia Tatum WO, Mani J et. al.

Dec 14th, 2021 - The objective of this clinical practice guideline is to provide recommendations on the indications and minimum standards for inpatient long-term video-electroencephalographic monitoring (LTVEM). The Working Group of the International League Agains...

ACR Appropriateness Criteria® Seizures-Child.
Journal of the American College of Radiology : JACR; , Trofimova A et. al.

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

Safety and recommendations for TMS use in healthy subjects and patient populations, wit...
Clinical Neurophysiology : Official Journal of the Intern... Rossi S, Antal A et. al.

Nov 28th, 2020 - This article is based on a consensus conference, promoted and supported by the International Federation of Clinical Neurophysiology (IFCN), which took place in Siena (Italy) in October 2018. The meeting intended to update the ten-year-old safety g...

ACR Appropriateness Criteria® Cerebrovascular Disease-Child.
Journal of the American College of Radiology : JACR; , Robertson RL et. al.

May 7th, 2020 - Stroke is an uncommon but an important and under-recognized cause of morbidity and mortality in children. Strokes may be due to either brain ischemia or intracranial hemorrhage. Common symptoms of pediatric acute stroke include headache, vomiting,...

ACR Appropriateness Criteria® Seizures and Epilepsy.
Journal of the American College of Radiology : JACR; , Lee RK et. al.

May 7th, 2020 - Seizures and epilepsy are a set of conditions that can be challenging to diagnose, treat, and manage. This document summarizes recommendations for imaging in different clinical scenarios for a patient presenting with seizures and epilepsy. MRI of ...

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Drugs  2,644 results see all →

Clinicaltrials.gov  1,558 results

Neuroimaging and CBD for Heroin Use Disorder

Mar 22nd, 2023 - This study will first use multimodal imaging in abstinent subjects with HUD to determine the neural circuits associated with the effects of CBD on craving and anxiety. Secondly, the investigators will conduct 1H MRS to characterize in-vivo neuroch...

EPX-100 (Clemizole Hydrochloride) as Add-on Therapy to Control Convulsive Seizures in Patients With Dravet Syndrome

Mar 22nd, 2023 - This is a global, multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of EPX-100 as adjunctive therapy in children and adult participants with Dravet Syndrome. The study consists of a 4-week observat...

An Open-label Extension Trial of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures

Mar 21st, 2023 - The purpose of this study is to assess the long-term safety and tolerability of CVL-865 as adjunctive therapy in participants with focal onset seizures.

Open-Label PoC Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy and Other Rare Genetic Epilepsies

Mar 21st, 2023 - The purpose of this proof-of-concept study is to evaluate ganaxolone as adjunctive therapy for uncontrolled seizures in female children with PCDH19 mutations and other rare genetic epilepsies. After establishing baseline seizure frequency, qualify...

Helicobacter Pylori Eradication Therapy for Epileptic Children

Mar 21st, 2023 - Helicobacter pylori (H. pylori) is a spiral-shaped Gram-negative bacterium, which causes chronic infection in more than 50% of human population. H. pylori infection is associated with several gastrointestinal disorders, such as gastritis and gastr...

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News  2,972 results

Complaints of cough and fatigue

Mar 20th, 2023 - The history and findings in this case are suggestive of non–small cell lung cancer (NSCLC) large cell carcinoma. Lung cancer is the most common cancer worldwide and has the highest mortality rate of all cancers.

First Treatment Approved for Rare Genetic Neurologic Disorder

Mar 13th, 2023 - The FDA approved trofinetide (Daybue), the first drug to treat adult and pediatric patients age 2 and older with Rett syndrome, drugmaker Acadia Pharmaceuticals announced Friday. "Now, for the first time after decades of clinical research, healthc...

5 non-COVID vaccine recommendations from ACIP
MDedge Family Medicine; Doug Campos-Outcalt, MD, MPA

Mar 7th, 2023 - Much of the work of the Advisory Committee on Immunization Practices (ACIP) in 2022 was devoted to vaccines to protect against coronavirus disease 2019 (COVID-19); details about the 4 available products can be found on the Centers for Disease Cont.

Antibiotic Combo Better for Severe Scrub Typhus Than Either Drug Alone

Mar 1st, 2023 - A dual antibiotic combination was better than either drug alone for treatment of severe scrub typhus, the randomized INTREST trial showed. For patients with this tropical mite-borne bacterial illness, intravenous doxycycline and azithromycin reduc...

Co-occurring psychogenic nonepileptic seizures and possible true seizures
Erica Stagliano, DO, MS

Mar 1st, 2023 - Psychogenic nonepileptic seizures (PNES) are a physical manifestation of a psychological disturbance. They are characterized by episodes of altered subjective experience and movements that can resemble epilepsy, syncope, or other paroxysmal disord.

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Patient Education  386 results see all →