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About 5,562 results

ALLMedicine™ Nasal Polyps Center

Research & Reviews  2,659 results

Bleomycin A5 suppresses Drp1‑mediated mitochondrial fission and induces apoptosis in hu...
https://doi.org/10.3892/ijmm.2020.4797
International Journal of Molecular Medicine; Wu F, Ma Y et. al.

Nov 25th, 2020 - Intralesional injection of bleomycin‑A5 (BLE‑A5) is a novel treatment for nasal polyps. Our previous study clarified that BLE‑A5 could induce nasal polyp‑derived fibroblast (NPDF) apoptosis in nasal polyps. However, the detailed mechanisms are sti...

The Role of Epigenetics in the Chronic Sinusitis with Nasal Polyp.
https://doi.org/10.1007/s11882-020-00976-8
Current Allergy and Asthma Reports; Liu T, Sun Y et. al.

Nov 25th, 2020 - Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common and heterogeneous inflammatory disease. The underlying epigenetic mechanisms and treatment of CRSwNP are partially understood. Of the different epigenetic changes in CRSwNP, histone dea...

The Effect of Dupilumab on Intractable Chronic Rhinosinusitis with Nasal Polyps in Japan.
https://doi.org/10.1002/lary.29230
The Laryngoscope BIBLIOGRAPHY; Fujieda S, Matsune S et. al.

Nov 23rd, 2020 - Dupilumab, which blocks the shared receptor component for interleukin-4 and interleukin-13, reduced polyp size, sinus opacification, and symptom severity, and was well tolerated in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) in...

Local IL-17 positive T cells are functionally associated with neutrophil infiltration a...
https://doi.org/10.1007/s00011-020-01424-z
Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]; Yu S, Cao C et. al.

Nov 23rd, 2020 - IL-17 plays essential roles in neutrophilic inflammation in the lower respiratory tract, however, the characteristics of local IL-17+ T cells in nasal inflammatory mucosa are not fully understood. We investigated the roles of IL-17+ T cells in reg...

EUFOREA Expert Board Meeting on Uncontrolled Severe Chronic Rhinosinusitis with Nasal P...
https://doi.org/10.1016/j.jaci.2020.11.013
The Journal of Allergy and Clinical Immunology; Bachert C, Han JK et. al.

Nov 23rd, 2020 - Uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) is the most bothersome phenotype of chronic rhinosinusitis, typically characterized by a type 2 inflammatory reaction and by comorbidities including asthma, N-ERD and allergies....

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Guidelines  1 results

Diagnosis and management of NSAID-Exacerbated Respiratory Disease (N-ERD)-a EAACI posit...
https://doi.org/10.1111/all.13599
Allergy Kowalski ML, Agache I et. al.

Sep 14th, 2018 - NSAID-exacerbated respiratory disease (N-ERD) is a chronic eosinophilic, inflammatory disorder of the respiratory tract occurring in patients with asthma and/or chronic rhinosinusitis with nasal polyps (CRSwNP), symptoms of which are exacerbated b...

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Drugs  17 results see all →

Clinicaltrials.gov  2,779 results

Bleomycin A5 suppresses Drp1‑mediated mitochondrial fission and induces apoptosis in hu...
https://doi.org/10.3892/ijmm.2020.4797
International Journal of Molecular Medicine; Wu F, Ma Y et. al.

Nov 25th, 2020 - Intralesional injection of bleomycin‑A5 (BLE‑A5) is a novel treatment for nasal polyps. Our previous study clarified that BLE‑A5 could induce nasal polyp‑derived fibroblast (NPDF) apoptosis in nasal polyps. However, the detailed mechanisms are sti...

The Role of Epigenetics in the Chronic Sinusitis with Nasal Polyp.
https://doi.org/10.1007/s11882-020-00976-8
Current Allergy and Asthma Reports; Liu T, Sun Y et. al.

Nov 25th, 2020 - Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common and heterogeneous inflammatory disease. The underlying epigenetic mechanisms and treatment of CRSwNP are partially understood. Of the different epigenetic changes in CRSwNP, histone dea...

The Effect of Dupilumab on Intractable Chronic Rhinosinusitis with Nasal Polyps in Japan.
https://doi.org/10.1002/lary.29230
The Laryngoscope BIBLIOGRAPHY; Fujieda S, Matsune S et. al.

Nov 23rd, 2020 - Dupilumab, which blocks the shared receptor component for interleukin-4 and interleukin-13, reduced polyp size, sinus opacification, and symptom severity, and was well tolerated in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) in...

Local IL-17 positive T cells are functionally associated with neutrophil infiltration a...
https://doi.org/10.1007/s00011-020-01424-z
Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]; Yu S, Cao C et. al.

Nov 23rd, 2020 - IL-17 plays essential roles in neutrophilic inflammation in the lower respiratory tract, however, the characteristics of local IL-17+ T cells in nasal inflammatory mucosa are not fully understood. We investigated the roles of IL-17+ T cells in reg...

EUFOREA Expert Board Meeting on Uncontrolled Severe Chronic Rhinosinusitis with Nasal P...
https://doi.org/10.1016/j.jaci.2020.11.013
The Journal of Allergy and Clinical Immunology; Bachert C, Han JK et. al.

Nov 23rd, 2020 - Uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) is the most bothersome phenotype of chronic rhinosinusitis, typically characterized by a type 2 inflammatory reaction and by comorbidities including asthma, N-ERD and allergies....

see more →

News  89 results

AstraZeneca's Asthma Drug Succeeds Late-Stage Nasal Polyposis Study
https://www.staging.medscape.com/viewarticle/937161

Sep 10th, 2020 - (Reuters) - AstraZeneca Plc said on Thursday its asthma treatment for a chronic inflammatory disease of the nasal passage linings, or sinuses, met main goals in a late-stage study. The treatment, Fasenra, showed a statistically significant improve...

AstraZeneca's Asthma Drug Succeeds Late-Stage Nasal Polyposis Study
https://www.medscape.com/viewarticle/937161

Sep 10th, 2020 - (Reuters) - AstraZeneca Plc said on Thursday its asthma treatment for a chronic inflammatory disease of the nasal passage linings, or sinuses, met main goals in a late-stage study. The treatment, Fasenra, showed a statistically significant improve...

Lies and Desperation: How, Why 'Professional Study Subjects' Skew Clinical Research
https://www.medscape.com/viewarticle/933869

Jul 13th, 2020 - When a clinical study on asthma launched in late 2019 in Louisiana, Patricia M. (not her real name) signed up. But she was not completely honest about her eligibility. "One of the criteria was you can't have taken prednisone steroids in the past t...

Lies and Desperation: How, Why 'Professional Study Subjects' Skew Clinical Research
https://www.staging.medscape.com/viewarticle/933869

Jul 13th, 2020 - When a clinical study on asthma launched in late 2019 in Louisiana, Patricia M. (not her real name) signed up. But she was not completely honest about her eligibility. "One of the criteria was you can't have taken prednisone steroids in the past t...

Fast Five Quiz: Nasal Polyps Nonsurgical Management
https://reference.medscape.com/viewarticle/922944_6

Jun 28th, 2020 - Medical management should be the first-line treatment of patients with nasal polyps. However, when patients are refractory to maximal medical management, surgical treatment may be required. In such cases, it is essential that patient education be ...

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Patient Education  17 results see all →