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About 3,018 results

ALLMedicine™ Nasal Polyps Center

Research & Reviews  1,078 results

Effects of Endoscopic Sinus Surgery for Eosinophilic Chronic Rhinosinusitis on Respirat...
https://doi.org/10.1177/01455613211032006
Ear, Nose, & Throat Journal; Terada T, Inui T et. al.

Jul 21st, 2021 - To confirm the relevance of upper and lower airway inflammation in eosinophilic chronic rhinosinusitis (ECRS), the effects of endoscopic sinus surgery (ESS) on lower airway functions and inflammation need to be examined in ECRS patients. Chronic r...

Occupational exposure influences control of disease in patients with chronic rhinosinus...
https://doi.org/10.4193/Rhin21.091
Rhinology Dietz de Loos DAE, Ronsmans S et. al.

Jul 21st, 2021 - Chronic rhinosinusitis (CRS) is a frequent condition that is treated by endoscopic sinus surgery (ESS) when medical treatment fails. Irritating or sensitizing airborne agents can contribute to uncontrolled CRS. A prior study showed a linear correl...

Pediatric Allergic Fungal Sinusitis: A Clinical Review.
https://doi.org/10.3928/19382359-20210706-01
Pediatric Annals; Mancuso RF

Jul 16th, 2021 - Allergic fungal sinusitis (AFS) is the most common type of fungal sinus infection. AFS is a robust allergic reaction to inhaled soil fungi that causes sinus inflammation, and the fungal debris then accumulates in the sinus cavities. This accumulat...

Biologics for chronic rhinosinusitis with nasal polyps: Economics and ethics.
https://doi.org/10.1002/alr.22864
International Forum of Allergy & Rhinology; Roland LT, Regenberg A et. al.

Jul 13th, 2021 - Biologics have recently been approved for use in chronic rhinosinusitis with nasal polyps patients. While effective in controlling disease on subjective and objective short-term outcome measures, limited data suggest that biologics have the potent...

Th17/1-Biased Inflammatory Environment Involved in the Response of Epithelial Cells to ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211518
Journal of Immunology Research; Xu G, Chen S et. al.

Jul 6th, 2021 - Several studies showed that IL-17A was significantly increased in nasal polyps (NPs). However, the source and characteristics of IL-17A-producing cells in NPs were not fully understood. We isolated mononuclear cells from NPs and uncinate tissues a...

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Guidelines  3 results

Considerations on biologicals for patients with allergic disease in times of the COVID-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300800
Allergy Vultaggio A, Agache I et. al.

Jun 6th, 2020 - The outbreak of the SARS-CoV-2-induced coronavirus disease 2019 (COVID-19) pandemic re-shaped doctor-patient interaction and challenged capacities of healthcare systems. It created many issues around the optimal and safest way to treat complex pat...

European Position Paper on Rhinosinusitis and Nasal Polyps 2020.
https://doi.org/10.4193/Rhin20.600
Rhinology Fokkens WJ, Lund VJ et. al.

Feb 23rd, 2020 - The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objective of the EPOS2020 guideline is to provide revised, up-to-date and cle...

Diagnosis and management of NSAID-Exacerbated Respiratory Disease (N-ERD)-a EAACI posit...
https://doi.org/10.1111/all.13599
Allergy Kowalski ML, Agache I et. al.

Sep 15th, 2018 - NSAID-exacerbated respiratory disease (N-ERD) is a chronic eosinophilic, inflammatory disorder of the respiratory tract occurring in patients with asthma and/or chronic rhinosinusitis with nasal polyps (CRSwNP), symptoms of which are exacerbated b...

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Drugs  16 results see all →

Clinicaltrials.gov  43 results

A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitus With Nasal Polyps
https://clinicaltrials.gov/ct2/show/NCT03280537

Mar 23rd, 2020 - The purpose of this study is to determine the efficacy and safety of omalizumab compared with placebo in adult patients with chronic rhinosinusitis with nasal polyps (CRSwNP) who have had an inadequate response to standard-of-care treatments. Stud...

A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps
https://clinicaltrials.gov/ct2/show/NCT03280550

Mar 23rd, 2020 - The purpose of this study is to determine the efficacy and safety of omalizumab compared with placebo in adult participants with chronic rhinosinusitis with nasal polyps (CRSwNP) who have had an inadequate response to standard-of-care treatments. ...

A Study to Evaluate the Effect of ACT-774312 in Subjects With Bilateral Nasal Polyposis
https://clinicaltrials.gov/ct2/show/NCT03688555

Mar 23rd, 2020 - The study will evaluate the effect of ACT-774312 on the nasal polyps and will assess the safety and tolerability of ACT-774312 in the patients with bilateral nasal polyposis

Nasal and Peripheral Blood Biomarkers of CRS Patients Before and After Surgical Intervention
https://clinicaltrials.gov/ct2/show/NCT03250429

Feb 5th, 2020 - Rhinosinusitis (RS) is a heterogenous disease, with variable etiologies, manifestations, and progression. Generally, RS can be divided into acute, subacute, and chronic RS, depending on the symptoms and duration of the disease. Most commonly, acut...

Analysis of Inflammation and Microbiome in Patients With Sinusitis and Asthma
https://clinicaltrials.gov/ct2/show/NCT02548598

Dec 17th, 2019 - This is a cross-sectional and non-interventional study to investigate mechanisms of disease in patients with asthma who have concomitant chronic sinusitis and/or nasal polyps (upper airway disease). Approximately 160 participants will be enrolled....

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News  56 results

Benralizumab Promising for Severe, Chronic Rhinosinusitis With Nasal Polyps
https://www.medscape.com/viewarticle/954835

Jul 15th, 2021 - Benralizumab (Fasenra) significantly reduced nasal polyp score (NPS) and average nasal blockage score (NBS) compared with placebo for patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) in a phase 3 trial. The randomized, multic...

Fast Five Quiz: Sinusitis With Nasal Polyps
https://reference.medscape.com/viewarticle/942877

Jun 18th, 2021 - Chronic rhinosinusitis with nasal polyps (CRSwNP) is a significant health problem that affects approximately 25%-30% of patients with chronic rhinosinusitis. CRSwNP can cause long-term symptoms such as prominent nasal obstruction, postnasal drip, ...

Nasal Polyp Treatment Algorithm: Allergists, Surgeons Agree
https://www.medscape.com/viewarticle/953001

Jun 14th, 2021 - Surgery precedes biologics but comes after saline irrigations and topical intranasal corticosteroids in a new treatment algorithm for US clinicians treating patients who have chronic rhinosinusitis with nasal polyps (CRSwNP). The consensus opinion...

Dupilumab an Option When Other Targeted Agents Fail in Aspirin-Exacerbated Respiratory Disease
https://www.medscape.com/viewarticle/946947

Mar 8th, 2021 - NEW YORK (Reuters Health) - Dupilumab, a monoclonal antibody targeting interleukin-4 (IL-4) receptor alpha, should be considered in patients with aspirin-exacerbated respiratory disease (AERD) whose symptoms are not adequately controlled by monocl...

AstraZeneca's Asthma Drug Succeeds Late-Stage Nasal Polyposis Study
https://www.staging.medscape.com/viewarticle/937161

Sep 11th, 2020 - (Reuters) - AstraZeneca Plc said on Thursday its asthma treatment for a chronic inflammatory disease of the nasal passage linings, or sinuses, met main goals in a late-stage study. The treatment, Fasenra, showed a statistically significant improve...

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Patient Education  11 results see all →