ALLMedicine™ Nasal Polyps Center

Mar 28th, 2023 - Dupilumab, a fully human monoclonal antibody, significantly improved quality of life and respiratory symptoms compared with placebo in a phase 3 trial of more than 900 adults with uncontrolled chronic obstructive pulmonary disease. In the study, k.

Mar 28th, 2023 - To determine the impact of comorbid migraine on quality of life (QOL) in chronic rhinosinusitis (CRS). A total of 213 adult patients with CRS were recruited. All participants completed the 22-item Sinonasal Outcome Test (SNOT-22), from which total...

Mar 28th, 2023 - IntroductionOmalizumab is used for the treatment of severe allergic asthma.ObjectiveThe aim of this study was to evaluate the clinical features and laboratory data of patients with severe allergic asthma classified as super-responder or non super-...

Mar 25th, 2023 - Hypoxia is involved in inflammation and immune response; however, its role in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) is not fully understood. We aimed to investigate the mechanisms by which hypoxia disrupts the nasal...

Mar 23rd, 2023 - Dupilumab, an IL-4/13 receptor inhibitor, is approved for the treatment of uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP). We evaluated the effectiveness and safety of dupilumab for CRSwNP based on retrospective 12-month follow-up ...

Feb 3rd, 2022 - To develop and validate revised classification criteria for eosinophilic granulomatosis with polyangiitis (EGPA). Patients with vasculitis or comparator diseases were recruited into an international cohort. The study proceeded in 5 phases: 1) iden...

Apr 6th, 2021 - We set out to create Consensus Guidelines, based on current evidence and relative risks of adverse effects and the costs of different treatments, which reflect the views of the British Rhinological Society (BRS) Council on where the use of biologi...

Jun 6th, 2020 - The outbreak of the SARS-CoV-2-induced coronavirus disease 2019 (COVID-19) pandemic re-shaped doctor-patient interaction and challenged capacities of healthcare systems. It created many issues around the optimal and safest way to treat complex pat...

Feb 23rd, 2020 - The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objective of the EPOS2020 guideline is to provide revised, up-to-date and cle...

Sep 15th, 2018 - NSAID-exacerbated respiratory disease (N-ERD) is a chronic eosinophilic, inflammatory disorder of the respiratory tract occurring in patients with asthma and/or chronic rhinosinusitis with nasal polyps (CRSwNP), symptoms of which are exacerbated b...

Mar 21st, 2023 - This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the effect of CBP-201 on a background of mometasone furoate nasal spray (MFNS) in reducing endoscopic nasal polyp score (NPS) and nasal congestion/obstruction sc...

Mar 20th, 2023 - Approximately 275 patients will be randomized to receive benralizumab 30 mg SC or matching placebo. After enrolment, eligible patients will enter a 6-week screening/run in period. Patients who meet eligibility criteria will be randomised 1:1 at We...

Mar 10th, 2023 - Topical and systemic steroids constitute the first choice in medical treatment for nasal polyps. Glucocorticoids sensitivity is significantly correlated with CST1 level in nasal secretions. The goal of this single-arm clinical trial based on a mul...

Mar 8th, 2023 - Chronic rhinosinusitis (CRS) is an inflammation of the nose and paranasal sinuses and is characterized by two or more symptoms, one of which should be either nasal blockage/obstruction/congestion or nasal discharge (anterior/posterior nasal drip),...

Mar 3rd, 2023 - The primary objective of this study is to compare the efficacy of intranasal administration of twice-daily doses of 186 and 372 µg of OPN-375 (fluticasone propionate) with placebo in subjects with chronic rhinosinusitis using the following co-prim...

Mar 28th, 2023 - Dupilumab, a fully human monoclonal antibody, significantly improved quality of life and respiratory symptoms compared with placebo in a phase 3 trial of more than 900 adults with uncontrolled chronic obstructive pulmonary disease. In the study, k.

Mar 10th, 2023 - The history and findings in this case are suggestive of eosinophilic asthma. Asthma is a common, chronic, and heterogeneous respiratory disease, most often characterized by chronic airway inflammation.

Oct 24th, 2022 - Sinus symptoms are frequently reported among patients. Causes include nasal polyps (the most common tumors of the nasal cavity) and chronic rhinosinusitis (CRS) (one of the most common chronic medical conditions in the world). These and other sinu...

Jul 13th, 2022 - Steroid-eluting implants inserted during or after sinus surgery may benefit patients with chronic sinusitis with or without nasal polyps, including those who can't tolerate oral steroids, a consensus study reports. Absorbable steroid-eluting sinus...

Jul 7th, 2022 - Theophylline added to saline nasal irrigation showed a hint of promise in treating postviral olfactory dysfunction related to COVID-19, data from the phase II SCENT2 trial suggested. In a study of 51 people with persistent olfactory dysfunction af...