ALLMedicine Anaphylaxis Center

Jun 4th, 2020 - Activation of the steroidogenic enzyme CYP11A1 was shown to be necessary for the development of peanut-induced intestinal anaphylaxis and IL-13 production in allergic mice. We determined if levels of CYP11A1 in peripheral blood T cells from peanut...

Jun 2nd, 2020 - No known therapies can prevent anaphylaxis. Bruton's tyrosine kinase (BTK) is an enzyme thought to be essential for high-affinity IgE receptor (FcεRI) signaling in human cells. We tested the hypothesis that FDA-approved BTK inhibitors (BTKi's) wou...

Jun 1st, 2020 - Urticaria and, to a lesser extent, angioedema are common occurrences in the pediatric population. There are multiple causes of acute and chronic urticaria and angioedema. Most causes are benign, although they can be worrisome for patients and thei...

May 31st, 2020 - The UK has high allergy prevalence rates, with 30-40% of the population affected by allergy. Hospital admissions for anaphylaxis, its most severe manifestation, have increased 7-fold since 1990 (1 ). It has long been thought by many that most pati...

May 30th, 2020 - Skin tests are the gold standard for detecting the culprit drug of anaphylaxis, and should ideally be performed after an interval of 4-6 weeks after the reaction to avoid false-negative results. However, when re-operation cannot be delayed and ear...

Sep 23rd, 2019 - David J. Amrol, MD reviewing Gabrielli S et al. J Allergy Clin Immunol Pract 2019 Sep/Oct

Sep 12th, 2019 - Aimmune Therapeutics, Inc. (Nasdaq:AIMT), a biopharmaceutical company developing treatments for potentially life-threatening food allergies, today announced that the Allergenic Products Advisory Committee (APAC) convened by the U.S. Food and Drug ...

Jul 31st, 2019 - Allergies can be life-threatening when they cause anaphylaxis, an extreme reaction with constriction of the airways and a sudden drop in blood pressure. Scientists have identified a subtype of immune cell that drives the production of antibodies (...

Dec 31st, 2017 - This article reviews the latest recommendations and clinical practice guidelines for peanut allergies among the pediatric population. Recommendations in this paper were compiled using information collected from a variety of publications of accredi.

Feb 14th, 2017 - Anaphylaxis is a severe, generalized allergic or hypersensitivity reaction that is rapid in onset and may cause death. Epinephrine (adrenaline) can be life-saving when administered as rapidly as possible once anaphylaxis is recognized. This clinic...

Jun 4th, 2020 - Activation of the steroidogenic enzyme CYP11A1 was shown to be necessary for the development of peanut-induced intestinal anaphylaxis and IL-13 production in allergic mice. We determined if levels of CYP11A1 in peripheral blood T cells from peanut...

Jun 2nd, 2020 - No known therapies can prevent anaphylaxis. Bruton's tyrosine kinase (BTK) is an enzyme thought to be essential for high-affinity IgE receptor (FcεRI) signaling in human cells. We tested the hypothesis that FDA-approved BTK inhibitors (BTKi's) wou...

Jun 1st, 2020 - Urticaria and, to a lesser extent, angioedema are common occurrences in the pediatric population. There are multiple causes of acute and chronic urticaria and angioedema. Most causes are benign, although they can be worrisome for patients and thei...

May 31st, 2020 - The UK has high allergy prevalence rates, with 30-40% of the population affected by allergy. Hospital admissions for anaphylaxis, its most severe manifestation, have increased 7-fold since 1990 (1 ). It has long been thought by many that most pati...

May 30th, 2020 - Skin tests are the gold standard for detecting the culprit drug of anaphylaxis, and should ideally be performed after an interval of 4-6 weeks after the reaction to avoid false-negative results. However, when re-operation cannot be delayed and ear...

May 18th, 2020 - Doctors are being asked to contact patients and prescribe alternatives after a class 2 recall of Emerade 500 microgram adrenaline auto-injector pens made by the Bausch & Lomb UK affiliate PharmaSwiss Česká republika. The drugs and devices regulato...

Apr 2nd, 2020 - "He was a legend in his own lifetime" was among the tributes to allergist Dr William Frankland who has died at the age of 108. Image credit: John Stillwell - WPA Pool/Getty Images The British Society for Allergy and Clinical Immunology (BSACI) als...

Feb 1st, 2020 - The Food and Drug Administration has approved the first drug to combat peanut allergy in children, (Palforzia, Aimmune Therapeutics), although those who take it must continue to avoid peanuts in their diets. The peanut (Arachis hypogaea) allergen.

Jan 30th, 2020 - The US Food and Drug Administration (FDA) has approved the first drug to combat peanut allergy in children, (Palforzia, Aimmune Therapeutics), although those who take it must continue to avoid peanuts in their diets. The peanut (Arachis hypogaea) ...

Dec 18th, 2019 - NEW YORK (Reuters Health) - The risk of anaphylactic reactions from contrast media used during cardiac catheterization is not increased in patients on beta-blockers or angiotensin-converting enzyme (ACE) inhibitors, according to results from a ret...