×
About 12,648 results

ALLMedicine Anaphylaxis Center

Research & Reviews  5,519 results

Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 ...
https://doi.org/10.1371/journal.pone.0233563
PloS One; Wang M, Strand MJ et. al.

Jun 4th, 2020 - Activation of the steroidogenic enzyme CYP11A1 was shown to be necessary for the development of peanut-induced intestinal anaphylaxis and IL-13 production in allergic mice. We determined if levels of CYP11A1 in peripheral blood T cells from peanut...

Bruton's tyrosine kinase inhibition effectively protects against human IgE-mediated ana...
https://doi.org/10.1172/JCI138448
The Journal of Clinical Investigation; Dispenza MC, Krier-Burris RA et. al.

Jun 2nd, 2020 - No known therapies can prevent anaphylaxis. Bruton's tyrosine kinase (BTK) is an enzyme thought to be essential for high-affinity IgE receptor (FcεRI) signaling in human cells. We tested the hypothesis that FDA-approved BTK inhibitors (BTKi's) wou...

Urticaria, Angioedema, and Anaphylaxis.
https://doi.org/10.1542/pir.2019-0056
Pediatrics in Review; Pier J, Bingemann TA

Jun 1st, 2020 - Urticaria and, to a lesser extent, angioedema are common occurrences in the pediatric population. There are multiple causes of acute and chronic urticaria and angioedema. Most causes are benign, although they can be worrisome for patients and thei...

Improved anaphylaxis referral rates to specialised services from an Emergency Department.
https://doi.org/10.1111/cea.13673
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology; Williams F, Ponsford M et. al.

May 31st, 2020 - The UK has high allergy prevalence rates, with 30-40% of the population affected by allergy. Hospital admissions for anaphylaxis, its most severe manifestation, have increased 7-fold since 1990 (1 ). It has long been thought by many that most pati...

Interpreting the results of early skin tests after perioperative anaphylaxis requires s...
https://doi.org/10.1007/s00540-020-02802-x
Journal of Anesthesia; Orihara M, Takazawa T et. al.

May 30th, 2020 - Skin tests are the gold standard for detecting the culprit drug of anaphylaxis, and should ideally be performed after an interval of 4-6 weeks after the reaction to avoid false-negative results. However, when re-operation cannot be delayed and ear...

see more →

Guidelines  45 results

Are Antihistamines and Steroids Helpful for Anaphylaxis?
https://www.jwatch.org/na49921/2019/09/24/are-antihistamines-and-steroids-helpful-anaphylaxis

Sep 23rd, 2019 - David J. Amrol, MD reviewing Gabrielli S et al. J Allergy Clin Immunol Pract 2019 Sep/Oct

FDA Allergenic Products Advisory Committee Votes to Support the Use of Aimmune’s PALFORZIA™ (AR101) for Peanut Allergy
http://ir.aimmune.com/news-releases/news-release-details/fda-allergenic-products-advisory-committee-votes-support-use

Sep 12th, 2019 - Aimmune Therapeutics, Inc. (Nasdaq:AIMT), a biopharmaceutical company developing treatments for potentially life-threatening food allergies, today announced that the Allergenic Products Advisory Committee (APAC) convened by the U.S. Food and Drug ...

Scientists discover immune cell subtype in mice that drives allergic reactions
https://www.nih.gov/news-events/news-releases/scientists-discover-immune-cell-subtype-mice-drives-allergic-reactions

Jul 31st, 2019 - Allergies can be life-threatening when they cause anaphylaxis, an extreme reaction with constriction of the airways and a sudden drop in blood pressure. Scientists have identified a subtype of immune cell that drives the production of antibodies (...

Practice Guidelines for Peanut Allergies
https://www.jpedhc.org/article/S0891-5245(17)30275-4/fulltext#s0025
Sitton, C.,et al.

Dec 31st, 2017 - This article reviews the latest recommendations and clinical practice guidelines for peanut allergies among the pediatric population. Recommendations in this paper were compiled using information collected from a variety of publications of accredi.

Epinephrine for First-aid Management of Anaphylaxis.
https://doi.org/10.1542/peds.2016-4006
Pediatrics Sicherer SH, Simons FER et. al.

Feb 14th, 2017 - Anaphylaxis is a severe, generalized allergic or hypersensitivity reaction that is rapid in onset and may cause death. Epinephrine (adrenaline) can be life-saving when administered as rapidly as possible once anaphylaxis is recognized. This clinic...

see more →

Drugs  241 results see all →

Clinicaltrials.gov  6,241 results

Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 ...
https://doi.org/10.1371/journal.pone.0233563
PloS One; Wang M, Strand MJ et. al.

Jun 4th, 2020 - Activation of the steroidogenic enzyme CYP11A1 was shown to be necessary for the development of peanut-induced intestinal anaphylaxis and IL-13 production in allergic mice. We determined if levels of CYP11A1 in peripheral blood T cells from peanut...

Bruton's tyrosine kinase inhibition effectively protects against human IgE-mediated ana...
https://doi.org/10.1172/JCI138448
The Journal of Clinical Investigation; Dispenza MC, Krier-Burris RA et. al.

Jun 2nd, 2020 - No known therapies can prevent anaphylaxis. Bruton's tyrosine kinase (BTK) is an enzyme thought to be essential for high-affinity IgE receptor (FcεRI) signaling in human cells. We tested the hypothesis that FDA-approved BTK inhibitors (BTKi's) wou...

Urticaria, Angioedema, and Anaphylaxis.
https://doi.org/10.1542/pir.2019-0056
Pediatrics in Review; Pier J, Bingemann TA

Jun 1st, 2020 - Urticaria and, to a lesser extent, angioedema are common occurrences in the pediatric population. There are multiple causes of acute and chronic urticaria and angioedema. Most causes are benign, although they can be worrisome for patients and thei...

Improved anaphylaxis referral rates to specialised services from an Emergency Department.
https://doi.org/10.1111/cea.13673
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology; Williams F, Ponsford M et. al.

May 31st, 2020 - The UK has high allergy prevalence rates, with 30-40% of the population affected by allergy. Hospital admissions for anaphylaxis, its most severe manifestation, have increased 7-fold since 1990 (1 ). It has long been thought by many that most pati...

Interpreting the results of early skin tests after perioperative anaphylaxis requires s...
https://doi.org/10.1007/s00540-020-02802-x
Journal of Anesthesia; Orihara M, Takazawa T et. al.

May 30th, 2020 - Skin tests are the gold standard for detecting the culprit drug of anaphylaxis, and should ideally be performed after an interval of 4-6 weeks after the reaction to avoid false-negative results. However, when re-operation cannot be delayed and ear...

see more →

News  551 results

Another Emerade Pen Recall: This time Emerade 500 Microgram
https://www.medscape.com/viewarticle/930739

May 18th, 2020 - Doctors are being asked to contact patients and prescribe alternatives after a class 2 recall of Emerade 500 microgram adrenaline auto-injector pens made by the Bausch & Lomb UK affiliate PharmaSwiss Česká republika. The drugs and devices regulato...

'Grandfather' of Clinical Allergy, Dr William Frankland, Dies at 108
https://www.medscape.com/viewarticle/928098

Apr 2nd, 2020 - "He was a legend in his own lifetime" was among the tributes to allergist Dr William Frankland who has died at the age of 108. Image credit: John Stillwell - WPA Pool/Getty Images The British Society for Allergy and Clinical Immunology (BSACI) als...

FDA okays Palforzia, first drug for peanut allergy in children
https://www.mdedge.com/clinicianreviews/article/216509/asthma/fda-okays-palforzia-first-drug-peanut-allergy-children?channel=284
Alicia Ault

Feb 1st, 2020 - The Food and Drug Administration has approved the first drug to combat peanut allergy in children, (Palforzia, Aimmune Therapeutics), although those who take it must continue to avoid peanuts in their diets. The peanut (Arachis hypogaea) allergen.

FDA OKs Palforzia, First Drug for Peanut Allergy in Children
https://www.medscape.com/viewarticle/924659

Jan 30th, 2020 - The US Food and Drug Administration (FDA) has approved the first drug to combat peanut allergy in children, (Palforzia, Aimmune Therapeutics), although those who take it must continue to avoid peanuts in their diets. The peanut (Arachis hypogaea) ...

Beta-Blockers, ACE Inhibitors Don’t Raise Anaphylaxis Risk From Cardiac Catheterization
https://www.medscape.com/viewarticle/922842

Dec 18th, 2019 - NEW YORK (Reuters Health) - The risk of anaphylactic reactions from contrast media used during cardiac catheterization is not increased in patients on beta-blockers or angiotensin-converting enzyme (ACE) inhibitors, according to results from a ret...

see more →

Patient Education  51 results see all →