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About 216,996 results

ALLMedicine™ Lung Cancer Center

Research & Reviews  102,023 results

miR‑7/SP1/TP53BP1 axis may play a pivotal role in NSCLC radiosensitivity.
https://doi.org/10.3892/or.2020.7824
Oncology Reports; Guo G, Li L et. al.

Oct 30th, 2020 - MicroRNA‑7 (miR‑7) has been identified as a tumor suppressor in non‑small cell lung cancer (NSCLC) and a radiosensitivity regulator. Numerous studies have revealed that specific protein 1 (SP1) plays a critical role in the tumorigenesis of various...

Auranofin inhibits the proliferation of lung cancer cells via necrosis and caspase‑depe...
https://doi.org/10.3892/or.2020.7818
Oncology Reports; Cui XY, Park SH et. al.

Oct 30th, 2020 - Auranofin, an inhibitor of thioredoxin reductase (TrxR), inhibits the growth of a variety of cancer cells. In the present study, various lung cancer cells were used to investigate the molecular basis of anti‑cancer effects of auranofin, including ...

Acetyl-bufalin shows potent efficacy against non-small-cell lung cancer by targeting th...
https://doi.org/10.1038/s41416-020-01135-6
British Journal of Cancer; Yang L, Zhou F et. al.

Oct 30th, 2020 - Cyclin-dependent kinase 9 (CDK9) is a promising prognostic marker and therapeutic target in cancers. Bufalin is an effective anti-tumour agent; however, the clinical application of bufalin is limited due to its high toxicity. Acetyl-bufalin, the b...

Co-Delivery Anticancer Drug Nanoparticles for Synergistic Therapy Against Lung Cancer C...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591005
Drug Design, Development and Therapy; Shen Y, TanTai J

Oct 30th, 2020 - This study aims to develop a novel co-delivery gefitinib and quercetin system loaded with PLGA-PEG nanoparticles and evaluate their antitumor activity in vitro and in vivo. Gef/Qur NPs were prepared and characterized. The release of drugs, stabili...

Variability in interpretation of low-dose chest CT using computerized assessment in a n...
https://doi.org/10.1007/s00330-020-07424-1
European Radiology; Hwang EJ, Goo JM et. al.

Oct 30th, 2020 - To evaluate the degree of variability in computer-assisted interpretation of low-dose chest CTs (LDCTs) among radiologists in a nationwide lung cancer screening (LCS) program, through comparison with a retrospective interpretation from a central l...

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Guidelines  583 results

Changes in Black-White Difference in Lung Cancer Incidence among Young Adults
https://academic.oup.com/jncics/article/4/4/pkaa055/5894724?searchresult=1
JNCI Cancer Spectrum; Jemal A

Aug 19th, 2020 - We previously reported that lung cancer incidence between Blacks and Whites younger than 40 years of age converged in women and approached convergence in men. Whether this pattern has continued in contemporary young birth cohorts is unclear.

Multi-center observational study on the adherence, quality of life, and adverse events in lung cancer patients treated with tyrosine kinase inhibitors
https://pubmed.ncbi.nlm.nih.gov/32746691/
Journal of Oncology Pharmacy Practice; Rosentreter J

Aug 2nd, 2020 - Cancer patients tend to prefer oral instead of parenteral chemotherapy. To date, there is little evidence on the medication adherence in cancer patients. We investigated medication adherence to tyrosine kinase inhibitors in patients suffering from...

Efficacy and safety of sintilimab plus pemetrexed and platinum as first-line treatment for locally advanced or metastatic nonsquamous non-small cell lung cancer: a randomized, double-blind, phase 3...
https://www.jto.org/article/S1556-0864(20)30595-5/pdf
Journal of Thoracic Oncology; Yang Y

Jul 24th, 2020 - Sintilimab, an anti-programmed death 1 antibody, plus pemetrexed and platinum had shown promising efficacy for nonsquamous non-small cell lung cancer in a phase 1b study. We conducted a randomized, double-blind, phase 3 study to compare the ef...

Peritumoral and intratumoral radiomic features predict survival outcomes among patients diagnosed in lung cancer screening
https://www.nature.com/articles/s41598-020-67378-8
Scientific Report; Perez-Morales J

Jun 28th, 2020 - The National Lung Screening Trial (NLST) demonstrated that screening with low-dose computed tomography (LDCT) is associated with a 20% reduction in lung cancer mortality. One potential limitation of LDCT screening is overdiagnosis of slow growing ...

Top Lung Cancer Research Presented at the ASCO20 Virtual Scientific Program Has Implications for Clinical Practice
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200223/full/

Jun 24th, 2020 - Although the ASCO Annual Meeting felt much different this year given the virtual format, the quality of research presented at the meeting was undiminished, particularly in the field of lung cancer. ASCO Daily News Expert Panel member Jared Weiss, ...

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Drugs  377 results see all →

Clinicaltrials.gov  108,777 results

miR‑7/SP1/TP53BP1 axis may play a pivotal role in NSCLC radiosensitivity.
https://doi.org/10.3892/or.2020.7824
Oncology Reports; Guo G, Li L et. al.

Oct 30th, 2020 - MicroRNA‑7 (miR‑7) has been identified as a tumor suppressor in non‑small cell lung cancer (NSCLC) and a radiosensitivity regulator. Numerous studies have revealed that specific protein 1 (SP1) plays a critical role in the tumorigenesis of various...

Auranofin inhibits the proliferation of lung cancer cells via necrosis and caspase‑depe...
https://doi.org/10.3892/or.2020.7818
Oncology Reports; Cui XY, Park SH et. al.

Oct 30th, 2020 - Auranofin, an inhibitor of thioredoxin reductase (TrxR), inhibits the growth of a variety of cancer cells. In the present study, various lung cancer cells were used to investigate the molecular basis of anti‑cancer effects of auranofin, including ...

Acetyl-bufalin shows potent efficacy against non-small-cell lung cancer by targeting th...
https://doi.org/10.1038/s41416-020-01135-6
British Journal of Cancer; Yang L, Zhou F et. al.

Oct 30th, 2020 - Cyclin-dependent kinase 9 (CDK9) is a promising prognostic marker and therapeutic target in cancers. Bufalin is an effective anti-tumour agent; however, the clinical application of bufalin is limited due to its high toxicity. Acetyl-bufalin, the b...

Co-Delivery Anticancer Drug Nanoparticles for Synergistic Therapy Against Lung Cancer C...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591005
Drug Design, Development and Therapy; Shen Y, TanTai J

Oct 30th, 2020 - This study aims to develop a novel co-delivery gefitinib and quercetin system loaded with PLGA-PEG nanoparticles and evaluate their antitumor activity in vitro and in vivo. Gef/Qur NPs were prepared and characterized. The release of drugs, stabili...

Variability in interpretation of low-dose chest CT using computerized assessment in a n...
https://doi.org/10.1007/s00330-020-07424-1
European Radiology; Hwang EJ, Goo JM et. al.

Oct 30th, 2020 - To evaluate the degree of variability in computer-assisted interpretation of low-dose chest CTs (LDCTs) among radiologists in a nationwide lung cancer screening (LCS) program, through comparison with a retrospective interpretation from a central l...

see more →

News  5,131 results

UK COVID-19 Update: Risk Tool Predicts Hospitalisation and Death
https://www.medscape.com/viewarticle/939493

Oct 20th, 2020 - These are the UK coronavirus stories you need to know about today. At least a third of lung cancer patients have already died since the beginning of the pandemic, and some deaths may have been labelled as COVID-19, the report said. UKLCC Chair, Pr...

High-risk Blacks Missed by Lung Cancer Screening Guidelines
https://www.medscape.com/viewarticle/939437

Oct 19th, 2020 - National guidelines failed to classify many younger African-American lung cancer patients as being eligible for lung cancer screening in a recent retrospective study, the lead author reported at the annual meeting of the American College of Chest ...

High-risk Blacks Missed by Lung Cancer Screening Guidelines
https://www.staging.medscape.com/viewarticle/939437

Oct 19th, 2020 - National guidelines failed to classify many younger African-American lung cancer patients as being eligible for lung cancer screening in a recent retrospective study, the lead author reported at the annual meeting of the American College of Chest ...

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Patient Education  105 results see all →