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About 225,282 results

ALLMedicine™ Lung Cancer Center

Research & Reviews  104,141 results

Perioperative Bypassing Agent Therapy for Pulmonary Pleomorphic Carcinoma with Acquired...
https://doi.org/10.5761/atcs.cr.20-00257
Annals of Thoracic and Cardiovascular Surgery : Official ... Sakai T, Azuma Y et. al.

Jan 21st, 2021 - A 74-year-old man was admitted with lung cancer, and preoperative blood test showed abnormal activated partial thromboplastin time (APTT). Coagulation factor screening and APTT mixing test achieved a diagnosis of acquired hemophilia A (AHA). Bypas...

Assessing Lung Cancer Absolute Risk Trajectory based on a Polygenic Risk Model.
https://doi.org/10.1158/0008-5472.CAN-20-1237
Cancer Research; Hung RJ, Warkentin MT et. al.

Jan 21st, 2021 - Lung cancer is the leading cause of cancer death globally. An improved risk stratification strategy can increase efficiency of low-dose computed tomography (LDCT) screening. Here we assessed whether individual's genetic background has clinical uti...

CKAP2L promotes non-small cell lung cancer progression through regulation of transcript...
https://doi.org/10.1158/0008-5472.CAN-20-1968
Cancer Research; Monteverde T, Sahoo S et. al.

Jan 21st, 2021 - Chromosomal instability (CIN) is a driver of clonal diversification and intra-tumor heterogeneity, providing genetic diversity that contributes to tumor progression. It is estimated that ∼80% of solid cancers, including non-small cell lung cancer ...

Advances in anti-BRAF therapies for lung cancer.
https://doi.org/10.1007/s10637-021-01068-8 10.1200/JCO.19.00934 10.1038/nature25183 10.1097/JTO.0000000000000625 10.1016/j.bbamcr.2007.05.001 10.1038/nature00766 10.1016/S0092-8674(04)00215-6 10.1016/j.bbamcr.2006.11.010 10.1016/j.ccr.2013.06.008 10.1016/S1470-2045(16)00077-2 10.1093/annonc/mdv128.07 10.1634/theoncologist.2017-0642 10.1093/jnci/dji055 10.1016/j.ctrv.2018.04.006 10.1158/0008-5472.CAN-08-2223 10.1200/JCO.2010.33.1280 10.1158/0008-5472.CAN-05-0404 10.1200/JCO.2011.35.9638 10.1097/PAS.0b013e31816597ca 10.1158/0008-5472.CAN-03-3591 10.1182/blood-2016-07-418434 10.1158/1535-7163.MCT-10-0799 10.1186/s12885-015-1811-y 10.2217/nnm.15.134 10.1038/s41388-018-0171-x 10.1016/j.ccell.2016.06.024 10.1038/nature23291 10.1038/ng.2682 10.1038/nm.4333 10.1038/nature09454 10.1056/nejmoa1103782 10.1158/1078-0432.CCR-14-0776 10.1634/theoncologist.2018-0295 10.1158/1541-7786.MCR-07-2001 10.1007/s40262-018-0703-0 10.1016/S0140-6736(12)60868-X 10.1016/S0140-6736(12)60398-5 10.1016/j.phrs.2018.08.013 10.1021/ml200004g 10.1200/JCO.2012.43.5966 10.1002/cncr.28864 10.1158/1078-0432.CCR-16-2923 10.1016/S1470-2045(18)30142-6 10.1056/nejmoa1908075 10.1016/j.canlet.2015.11.015 10.1158/0008-5472.CAN-07-6787 10.1158/0008-5472.CAN-10-2954 10.1158/2159-8290.CD-12-0386 10.1186/s12967-018-1568-6 10.1158/1078-0432.CCR-13-0657 10.1001/jama.2014.3741 10.1016/j.lungcan.2015.11.006 10.1002/cncr.29042 10.1093/annonc/mdt495 10.1016/S1470-2045(17)30679-4 10.1016/S1470-2045(16)30146-2 10.1200/JCO.2017.35.15_suppl.9073 10.1038/nature14982 10.1016/j.ccell.2015.08.001 10.1016/j.ccell.2015.08.002 10.1016/j.ccell.2014.11.006 10.1158/1078-0432.CCR-10-3408 10.18632/oncotarget.17937 10.1016/j.jtho.2016.05.001 10.18632/oncotarget.25948 10.1111/1759-7714.12177 10.1200/JCO.19.00489 10.1634/theoncologist.2018-0296 10.1056/NEJMoa1210093
Investigational New Drugs; Roviello G, D'Angelo A et. al.

Jan 21st, 2021 - Non-small cell lung cancer (NSCLC) is one of the most frequent causes of mortality in the western world. v-raf murine sarcoma viral oncogene homolog B (BRAF) is a member of the Raf kinase family and plays a critical role in cellular growth, prolif...

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Guidelines  587 results

Changes in Black-White Difference in Lung Cancer Incidence among Young Adults
https://academic.oup.com/jncics/article/4/4/pkaa055/5894724?searchresult=1
JNCI Cancer Spectrum; Jemal A

Aug 19th, 2020 - We previously reported that lung cancer incidence between Blacks and Whites younger than 40 years of age converged in women and approached convergence in men. Whether this pattern has continued in contemporary young birth cohorts is unclear.

Multi-center observational study on the adherence, quality of life, and adverse events in lung cancer patients treated with tyrosine kinase inhibitors
https://pubmed.ncbi.nlm.nih.gov/32746691/
Journal of Oncology Pharmacy Practice; Rosentreter J

Aug 2nd, 2020 - Cancer patients tend to prefer oral instead of parenteral chemotherapy. To date, there is little evidence on the medication adherence in cancer patients. We investigated medication adherence to tyrosine kinase inhibitors in patients suffering from...

Efficacy and safety of sintilimab plus pemetrexed and platinum as first-line treatment for locally advanced or metastatic nonsquamous non-small cell lung cancer: a randomized, double-blind, phase 3...
https://www.jto.org/article/S1556-0864(20)30595-5/pdf
Journal of Thoracic Oncology; Yang Y

Jul 24th, 2020 - Sintilimab, an anti-programmed death 1 antibody, plus pemetrexed and platinum had shown promising efficacy for nonsquamous non-small cell lung cancer in a phase 1b study. We conducted a randomized, double-blind, phase 3 study to compare the ef...

Peritumoral and intratumoral radiomic features predict survival outcomes among patients diagnosed in lung cancer screening
https://www.nature.com/articles/s41598-020-67378-8
Scientific Report; Perez-Morales J

Jun 28th, 2020 - The National Lung Screening Trial (NLST) demonstrated that screening with low-dose computed tomography (LDCT) is associated with a 20% reduction in lung cancer mortality. One potential limitation of LDCT screening is overdiagnosis of slow growing ...

Top Lung Cancer Research Presented at the ASCO20 Virtual Scientific Program Has Implications for Clinical Practice
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200223/full/

Jun 24th, 2020 - Although the ASCO Annual Meeting felt much different this year given the virtual format, the quality of research presented at the meeting was undiminished, particularly in the field of lung cancer. ASCO Daily News Expert Panel member Jared Weiss, ...

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Drugs  381 results see all →

Clinicaltrials.gov  112,937 results

Nivolumab Indication in Small Cell Lung Cancer Withdrawn in U.S. Market
https://ascopost.com/issues/january-25-2021/nivolumab-indication-in-small-cell-lung-cancer-withdrawn-in-us-market/

Jan 24th, 2021 - On December 29, Bristol Myers Squibb issued the following statement on nivolumab’s small cell lung cancer (SCLC) indication in the United States. In 2018, nivolumab was granted accelerated approval by the U.S. Food and Drug Administration (FDA) fo...

Perioperative Bypassing Agent Therapy for Pulmonary Pleomorphic Carcinoma with Acquired...
https://doi.org/10.5761/atcs.cr.20-00257
Annals of Thoracic and Cardiovascular Surgery : Official ... Sakai T, Azuma Y et. al.

Jan 21st, 2021 - A 74-year-old man was admitted with lung cancer, and preoperative blood test showed abnormal activated partial thromboplastin time (APTT). Coagulation factor screening and APTT mixing test achieved a diagnosis of acquired hemophilia A (AHA). Bypas...

Assessing Lung Cancer Absolute Risk Trajectory based on a Polygenic Risk Model.
https://doi.org/10.1158/0008-5472.CAN-20-1237
Cancer Research; Hung RJ, Warkentin MT et. al.

Jan 21st, 2021 - Lung cancer is the leading cause of cancer death globally. An improved risk stratification strategy can increase efficiency of low-dose computed tomography (LDCT) screening. Here we assessed whether individual's genetic background has clinical uti...

CKAP2L promotes non-small cell lung cancer progression through regulation of transcript...
https://doi.org/10.1158/0008-5472.CAN-20-1968
Cancer Research; Monteverde T, Sahoo S et. al.

Jan 21st, 2021 - Chromosomal instability (CIN) is a driver of clonal diversification and intra-tumor heterogeneity, providing genetic diversity that contributes to tumor progression. It is estimated that ∼80% of solid cancers, including non-small cell lung cancer ...

see more →

News  7,133 results

Many ED Visits May Be Preventable for Patients With NSCLC
https://www.medscape.com/viewarticle/944347

Jan 18th, 2021 - Nearly a quarter of ED visits were deemed preventable in a single-center study of patients with non–small cell lung cancer. The leading cause of ED visits in the study was the cancer itself, although many visits were unrelated to non–small cell lu...

Baby Gets Cancer From Mother During Birth: First Report
https://www.medscape.com/viewarticle/944204

Jan 14th, 2021 - Cancer can be transmitted from a mother with cervical cancer to a newborn when the baby passes through the birth canal. That's the conclusion of two ground-breaking cases from Japan in which investigators describe lung cancer in two boys that "pro...

Immunotherapy Plus Chemo Bests Chemo Alone in Asians With Advanced NSCLC
https://www.medscape.com/viewarticle/944056

Jan 13th, 2021 - NEW YORK (Reuters Health) - In Chinese patients with advanced non-squamous non-small-cell lung cancer (NSCLC), adding camrelizumab to carboplatin and pemetrexed was more effective and improved progression-free survival (PFS) compared to chemothera...

US Cancer Death Rates Drop for Second Year in a Row
https://www.medscape.com/viewarticle/944030

Jan 12th, 2021 - For the second year in a row, mortality from cancer has fallen in the United States, driven largely by reductions in the incidence of, and death from, non-small cell lung cancer (NSCLC) in men and women, according to a new report from the American...

NCCN Guidelines Pave Way for Improving Lung Cancer Survival
https://www.medscape.com/viewarticle/943159

Jan 6th, 2021 - This transcript has been edited for clarity. Hello. This is Mark Kris from Memorial Sloan Kettering, speaking today about a Thanksgiving gift that I very happily learned about just a day or two before the holiday: the newest version of the NCCN gu...

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Patient Education  103 results see all →