About 42,705 results

ALLMedicine™ Chronic Obstructive Pulmonary Disease Center

Research & Reviews  14,354 results

Inhibition of LC3-associated phagocytosis in COPD and in response to cigarette smoke.
Therapeutic Advances in Respiratory Disease; Asare PF, Tran HB et. al.

Dec 3rd, 2021 - In chronic obstructive pulmonary disease (COPD), defective macrophage phagocytic clearance of cells undergoing apoptosis by efferocytosis may lead to secondary necrosis of the uncleared cells and contribute to airway inflammation. The precise mech...

Previous tuberculosis disease as a risk factor for chronic obstructive pulmonary diseas...
Thorax Kamenar K, Hossen S et. al.

Dec 3rd, 2021 - Risk factors for COPD in high-income settings are well understood; however, less attention has been paid to contributors of COPD in low-income and middle-income countries (LMICs) such as pulmonary tuberculosis. We sought to study the association b...

Lower Prevalence of Osteoporosis in Patients with COPD Taking Anti-Inflammatory Compoun...
International Journal of Chronic Obstructive Pulmonary Di... Kahnert K, Jörres RA et. al.

Dec 3rd, 2021 - Patients with chronic obstructive pulmonary disease (COPD) often have osteoporosis and diabetes as comorbid conditions. Anti-diabetic medication, including metformin, has protective effects on osteoporosis in experimental studies. We therefore stu...

Risk factors in central retinal vein occlusion: A multi-center case-control study condu...
European Journal of Ophthalmology; Edoardo TB, Fernanda P et. al.

Dec 3rd, 2021 - To explore the risk factors for central retinal vein occlusion (CRVO) by comparing a large sample of patients with healthy controls. Multi-center case-control study. The study group includes patients affected by central retinal vein occlusion, con...

Clinical Outcomes of Noninvasive Ventilation in Asthma, Bronchiectasis, and Other COPD.
Southern Medical Journal; Nemeh C, Dongarwar D et. al.

Dec 3rd, 2021 - Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality and disability worldwide. Use of noninvasive ventilation (NIV) appears to be associated with a significant decrease in frequency of exacerbation, hospital admissions, and...

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Guidelines  21 results

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice ...
Annals of Internal Medicine; Lee RA, Centor RM et. al.

Apr 6th, 2021 - Antimicrobial overuse is a major health care issue that contributes to antibiotic resistance. Such overuse includes unnecessarily long durations of antibiotic therapy in patients with common bacterial infections, such as acute bronchitis with chro...

Long-Term Mechanical Ventilation: Recommendations of the Swiss Society of Pulmonology.
Respiration; International Review of Thoracic Diseases; Janssens JP, Michel F et. al.

Dec 11th, 2020 - Long-term mechanical ventilation is a well-established treatment for chronic hypercapnic respiratory failure (CHRF). It is aimed at improving CHRF-related symptoms, health-related quality of life, survival, and decreasing hospital admissions. In S...

Long-Term Noninvasive Ventilation in Chronic Stable Hypercapnic Chronic Obstructive Pul...
American Journal of Respiratory and Critical Care Medicine; Macrea M, Oczkowski S et. al.

Aug 17th, 2020 - Background: Noninvasive ventilation (NIV) is used for patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. However, evidence for clinical efficacy and optimal management of therapy is limited.Target Audience: Patient...

Adult Patients with Respiratory Distress: Current Evidence-based Recommendations for Pr...
The Western Journal of Emergency Medicine; Hodroge SS, Glenn M et. al.

Jul 30th, 2020 - We developed evidence-based recommendations for prehospital evaluation and treatment of adult patients with respiratory distress. These recommendations are compared with current protocols used by the 33 local emergency medical services agencies (L...

ACR Appropriateness Criteria® Chronic Dyspnea-Noncardiovascular Origin.
Journal of the American College of Radiology : JACR; , McComb BL et. al.

Nov 6th, 2018 - Chronic dyspnea may result from a variety of disorders of cardiovascular, pulmonary, gastrointestinal, neuromuscular, systemic, and psychogenic etiology. This article discusses guidelines for the initial imaging of six variants for chronic dyspnea...

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Drugs  121 results see all →

Clinicaltrials.gov  979 results

A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

Nov 23rd, 2021 - The purpose of this study is to determine if ensifentrine is safe and effective for the treatment of patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)

Nov 23rd, 2021 - This is a multi-center, open-label study for eligible participants who completed all scheduled study visits during the Treatment Period of Study RIN-PH-304. Participants who provide informed consent for this open-label extension study on or prior ...

MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer

Nov 23rd, 2021 - PRIMARY OBJECTIVES: I. Immunogenicity of the vaccine, assessed at week 12, based on the increase in IgG anti-MUC1 antibody titer over the pre-vaccination levels. II. Safety, assessed throughout the trial and continued observation for 24 weeks. SEC...

Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)

Nov 23rd, 2021 - RELIANCE is a U.S.-based pragmatic clinical trial funded by the Patient-Centered Outcomes Research Institute (PCORI) to compare long-term use of roflumilast vs. azithromycin in up to 3,200 patients. It is intended to support hospital efforts to re...

Unrefined Salmon Oil as Dietary Supplement in Patient With Chronic Obstructive Pulmonary Disease

Nov 23rd, 2021 - This study is a double-blind, placebo-controlled, randomized trial, investigating unrefined salmon oil, CARDIO®, additional to standard care for patients suffering from COPD. The investigational product is an unrefined salmon oil based soft-gel fo...

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News  1,593 results

COPD: Real-world Safety and Efficacy of Budesonide-Formoterol Vs Fluticasone-Salmeterol

Nov 18th, 2021 - Takeaway Budesonide-formoterol inhaler was as effective as fluticasone-salmeterol in reducing the incidence of moderate-severe exacerbations in patients with chronic obstructive pulmonary disease (COPD) who had ≥1 exacerbation in the year prior to...

EHR Alerts Have No Impact on Inpatient HF Treatment or Outcomes

Nov 15th, 2021 - When provided at the bedside of patients hospitalized for heart failure, an electronic health record (EHR) alert with prognostic information did not improve outcomes or appear to have any impact on what treatments were offered. There was no signal...

Pulmonary rehabilitation: Similar benefit in both IPF and COPD patients
Walter Alexander, MDedge News

Nov 12th, 2021 - Patients with idiopathic pulmonary fibrosis (IPF) complete and respond to pulmonary rehabilitation at rates similar to patients with chronic obstructive pulmonary disease (COPD), according to results of a real-world study. The findings reported in.

Understudied Low-Lung-Function State Tied to Increased Risk of Respiratory Problems and Death

Nov 12th, 2021 - NEW YORK (Reuters Health) - A particular pattern of low-scoring lung-capacity tests known as preserved-ratio impaired spirometry or PRISm is associated with respiratory symptoms, cardiovascular comorbidities, and an increased risk of death in olde...

Year in Review: COPD

Nov 8th, 2021 - While outwardly 2021 was a quiet year in the field of chronic obstructive pulmonary disease (COPD), with no major research breakthroughs or new drug approvals, that doesn't mean it can be written off as dull. For starters, there's the growing prob...

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Patient Education  14 results see all →