ALLMedicine™ Chronic Obstructive Pulmonary Disease Center

Mar 28th, 2023 - Dupilumab, a fully human monoclonal antibody, significantly improved quality of life and respiratory symptoms compared with placebo in a phase 3 trial of more than 900 adults with uncontrolled chronic obstructive pulmonary disease. In the study, k.

Mar 28th, 2023 - The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD) has been the subject of much uncertainty. COPD clinical guidelines currently recommend selective use of ICS. ICS are not recommended as monotherapy for peopl...

Mar 28th, 2023 - Beta-lactam antibiotics commonly cause immune thrombocytopenia. Cross-reactivity in patients with drug-induced immune thrombocytopenia has rarely been reported. In this study, we describe the case of a 79-year-old man who developed thrombocytopeni...

Mar 28th, 2023 - CO2 is produced during aerobic respiration. Normally, levels of CO2 in the blood are tightly regulated but pCO2 can rise (hypercapnia, pCO2 > 45 mmHg) in patients with lung diseases e.g. Chronic Obstructive Pulmonary Disease (COPD). Hypercapnia is...

Mar 28th, 2023 - Plastics have conveyed great benefits to humanity and made possible some of the most significant advances of modern civilization in fields as diverse as medicine, electronics, aerospace, construction, food packaging, and sports. It is now clear, h...

May 18th, 2022 - SAN FRANCISCO -- For neighborhoods near a major coking operation in Pittsburgh, its shutdown at the end of 2015 was followed by markedly lower rates of respiratory disease hospitalizations, researchers reported here. Inpatient admissions for ch...

May 11th, 2022 - Chronic obstructive pulmonary disease (COPD) is an irreversible reduction of airflow in the lungs. Progression to severe disease can prevent participation in normal activities because of deterioration of lung function. In 2020 it was estimated tha...

Apr 6th, 2021 - Antimicrobial overuse is a major health care issue that contributes to antibiotic resistance. Such overuse includes unnecessarily long durations of antibiotic therapy in patients with common bacterial infections, such as acute bronchitis with chro...

Dec 11th, 2020 - Long-term mechanical ventilation is a well-established treatment for chronic hypercapnic respiratory failure (CHRF). It is aimed at improving CHRF-related symptoms, health-related quality of life, survival, and decreasing hospital admissions. In S...

Aug 17th, 2020 - Background: Noninvasive ventilation (NIV) is used for patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. However, evidence for clinical efficacy and optimal management of therapy is limited.Target Audience: Patient...

Mar 24th, 2023 - Physical inactivity is a growing health problem in the United States, especially for older people with chronic diseases such as COPD; in fact people with COPD are among the least active. Low levels of physical activity (PA) are associated with neg...

Mar 23rd, 2023 - Chronic obstructive pulmonary disease (COPD) is a frequently underdiagnosed major health problem, responsible for over 250 million cases of disease and 3 million deaths (5% of all deaths) worldwide in 2015. Despite resulting in more than $30 billi...

Mar 20th, 2023 - Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide and a major cause of morbidity in the UK. Inhaled corticosteroids (ICS) are frequently prescribed to patients with COPD and these medications represent a ma...

Mar 16th, 2023 - Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (≥300/μL). Eligible patients must have a hist...

Mar 15th, 2023 - Pulmonary rehabilitation (PR), composed of exercise training, education, and self-management strategies, is the standard of care for managing individuals with chronic obstructive pulmonary disease (COPD). PR improves dyspnea, functional exercise c...

Mar 29th, 2023 - Individuals with a history of atopic disease, such as asthma and eczema (a.k.a. atopic dermatitis), are at significantly increased risk for developing osteoarthritis (OA), analysis of medical insurance claims indicated. With some 110,000 people wi...

Mar 28th, 2023 - Dupilumab, a fully human monoclonal antibody, significantly improved quality of life and respiratory symptoms compared with placebo in a phase 3 trial of more than 900 adults with uncontrolled chronic obstructive pulmonary disease. In the study, k.

Mar 24th, 2023 - Independent of pulmonary function, improvement in exercise capacity and quality of life after lung volume reduction using endobronchial valves (EBV) are associated with a significant survival benefit, according to study results published in Respir.

Among more than 195,000 state quitline callers, 32.3% reported having one or more of the following chronic diseases: asthma, coronary artery disease, chronic obstructive pulmonary disease and diabetes. Callers who had a chronic disease were typica...

Mar 21st, 2023 - For patients admitted to the intensive care unit with severe community-acquired pneumonia, treatment with hydrocortisone led to a lower risk of death at 28 days versus placebo, a phase III randomized trial in France showed. Among nearly 800 patien...