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About 57,220 results

ALLMedicine™ Chronic Obstructive Pulmonary Disease Center

Research & Reviews  17,850 results

The Role of Bronchoscopic Lung Volume Reduction in COPD
https://www.mdedge.com/chestphysician/article/255514/copd/role-bronchoscopic-lung-volume-reduction-copd
Javier Diaz-Mendoza, MD, FCCP

Jul 1st, 2022 - Patients with chronic obstructive pulmonary disease (COPD) typically have emphysema, which involves destruction of alveoli and reduction of elasticity leading to airflow obstruction, air trapping, and hyperinflation. Over time, these changes cause.

Inhaled Corticosteroid Withdrawal and Change in Lung Function in Primary Care Chronic O...
https://doi.org/10.1513/AnnalsATS.202111-1238OC
Annals of the American Thoracic Society; Whittaker HR, Wing K et. al.

Jun 30th, 2022 - In COPD, inhaled corticosteroids (ICS) are associated with pneumonia highlighting the importance of investigating subgroups of patients who may benefit from prolonged ICS use. Despite this, the WISDOM trial found a greater decline in forced expira...

Assessing the contribution of rare genetic variants to phenotypes of chronic obstructiv...
https://doi.org/10.1093/hmg/ddac117
Human Molecular Genetics; Kim W, Hecker J et. al.

Jun 30th, 2022 - Genetic variation has a substantial contribution to chronic obstructive pulmonary disease (COPD) and lung function measurements. Heritability estimates using genome-wide genotyping data can be biased if analyses do not appropriately account for th...

Disease-related knowledge in people with chronic obstructive pulmonary disease and thei...
https://doi.org/10.1111/jocn.16433
Journal of Clinical Nursing; Matarese M, Lyons KS et. al.

Jun 30th, 2022 - To assess the level of chronic obstructive pulmonary disease (COPD)-related knowledge within patient and informal caregiver dyads, and to identify factors influencing the knowledge level considering the interdependence within the dyads. Patients w...

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Guidelines  24 results

Here's What Happened to Asthma, COPD Admissions After a Big Polluter Shut Down
https://www.medpagetoday.com/meetingcoverage/ats/98781
MedPage Today; Gever J.

May 18th, 2022 - SAN FRANCISCO -- For neighborhoods near a major coking operation in Pittsburgh, its shutdown at the end of 2015 was followed by markedly lower rates of respiratory disease hospitalizations, researchers reported here. Inpatient admissions for ch...

Screening for Chronic Obstructive Pulmonary Disease: US Preventive Services Task Force ...
https://doi.org/10.1001/jama.2022.5692
JAMA , Mangione CM et. al.

May 11th, 2022 - Chronic obstructive pulmonary disease (COPD) is an irreversible reduction of airflow in the lungs. Progression to severe disease can prevent participation in normal activities because of deterioration of lung function. In 2020 it was estimated tha...

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice ...
https://doi.org/10.7326/M20-7355
Annals of Internal Medicine; Lee RA, Centor RM et. al.

Apr 6th, 2021 - Antimicrobial overuse is a major health care issue that contributes to antibiotic resistance. Such overuse includes unnecessarily long durations of antibiotic therapy in patients with common bacterial infections, such as acute bronchitis with chro...

Long-Term Mechanical Ventilation: Recommendations of the Swiss Society of Pulmonology.
https://doi.org/10.1159/000510086
Respiration; International Review of Thoracic Diseases; Janssens JP, Michel F et. al.

Dec 11th, 2020 - Long-term mechanical ventilation is a well-established treatment for chronic hypercapnic respiratory failure (CHRF). It is aimed at improving CHRF-related symptoms, health-related quality of life, survival, and decreasing hospital admissions. In S...

Long-Term Noninvasive Ventilation in Chronic Stable Hypercapnic Chronic Obstructive Pul...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427384
American Journal of Respiratory and Critical Care Medicine; Macrea M, Oczkowski S et. al.

Aug 17th, 2020 - Background: Noninvasive ventilation (NIV) is used for patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. However, evidence for clinical efficacy and optimal management of therapy is limited.Target Audience: Patient...

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Drugs  143 results see all →

Clinicaltrials.gov  2,841 results

NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)
https://clinicaltrials.gov/ct2/show/NCT02327897

Jun 24th, 2022 - This study will be a prospective, longitudinal, observational, single-center, exploratory, natural history study to collect samples and data that will enable prospective explorations of the interaction between environmental exposures and disease p...

Role of Genetic Factors in the Development of Lung Disease
https://clinicaltrials.gov/ct2/show/NCT00001532

Jun 24th, 2022 - This study is designed to evaluate genetic mechanisms of lung disease by surveying polymorphic genes involved in respiratory function and examining gene expression in the lung cells of individuals with pulmonary disease (e.g., alpha 1-antitrypsin ...

Swiss Chronic Obstructive Pulmonary Disease (COPD) Management Cohort
https://clinicaltrials.gov/ct2/show/NCT02065921

Jun 23rd, 2022 - Background Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory disease of the lungs, which is most commonly caused by smoking. It is characterized as not fully reversible airflow limitation, chronic cough and dyspnoea. Being the fourth...

Long-term Observational Study of the Safety of Roflumilast
https://clinicaltrials.gov/ct2/show/NCT03381573

Jun 23rd, 2022 - Rationale and background Roflumilast is licensed (i) for maintenance treatment of severe chronic obstructive pulmonary disease (COPD) (FEV1 post-bronchodilator less than 50% predicted) associated with chronic bronchitis (CB) in adult patients with...

Prevention of Acute Exacerbation in Subjects With COPD by Bacterial Decolonization in Lower Respiratory Tract
https://clinicaltrials.gov/ct2/show/NCT03449459

Jun 23rd, 2022 - Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease characterized by incomplete reversible airflow limitation, small airway obstruction and alveolar structural damage. About 3 million patients die from COPD every year aro...

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News  2,009 results

The Role of Bronchoscopic Lung Volume Reduction in COPD
https://www.mdedge.com/chestphysician/article/255514/copd/role-bronchoscopic-lung-volume-reduction-copd
Javier Diaz-Mendoza, MD, FCCP

Jul 1st, 2022 - Patients with chronic obstructive pulmonary disease (COPD) typically have emphysema, which involves destruction of alveoli and reduction of elasticity leading to airflow obstruction, air trapping, and hyperinflation. Over time, these changes cause.

Higher Hospital Readmission Rates Linked to Adverse Effects in Pneumonia
https://www.medscape.com/viewarticle/976344

Jun 29th, 2022 - Adding to the debate over the value of hospital readmission rates, a new study links the data to higher rates of adverse events in patients treated for pneumonia. For each interquartile range increase in the readmission rate in a sample of 46,047 ...

ECG Challenge: Uncontrolled COPD or Something Else?
https://www.medscape.com/viewarticle/975590

Jun 27th, 2022 - A 70-year-old man with a history of chronic obstructive pulmonary disease (COPD), treated with inhalers, presents to his pulmonologist with worsening shortness of breath which he thinks is related to COPD. He has noted intermittent palpitations. H...

IL-6 Antibody Mitigates Mucus Hypersecretion in COPD
https://www.medscape.com/viewarticle/976014

Jun 22nd, 2022 - Treatment with an interleukin-6 neutralizing antibody significantly reduced airway mucus hypersecretion (AMH) in chronic obstructive pulmonary disease (COPD), based on data from human and mouse cells in a human organoid model. AMH plays a large pa...

IL-6 antibody mitigates mucus hypersecretion in COPD
https://www.mdedge.com/chestphysician/article/255574/copd/il-6-antibody-mitigates-mucus-hypersecretion-copd
Heidi Splete, MDedge News

Jun 21st, 2022 - Treatment with an interleukin-6 neutralizing antibody significantly reduced airway mucus hypersecretion (AMH) in chronic obstructive pulmonary disease (COPD), based on data from human and mouse cells in a human organoid model. AMH plays a large pa.

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Patient Education  21 results see all →