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About 25,720 results

ALLMedicine™ Systemic Lupus Erythematosus Center

Research & Reviews  8,886 results

Reversible basal ganglia lesions in a patient with systemic lupus erythematosus.
https://doi.org/10.1093/rheumatology/keab621
Rheumatology (Oxford, England); Arinuma Y, Asakura H et. al.

Jul 31st, 2021 - Reversible basal ganglia lesions in a patient with systemic lupus erythematosus.|2021|Arinuma Y,Asakura H,Yamaoka K,|

Progressive multifocal leukoencephalopathy in systemic lupus erythematosus managed with...
https://doi.org/10.1177/09612033211035443
Lupus Lan TY, Chen YS et. al.

Jul 31st, 2021 - Progressive multifocal leukoencephalopathy (PML) is one of the rare but lethal infectious complication in patients with SLE, manifesting progressive central nervous demyelination caused by JC virus (JCV). There have been no effective antiviral age...

T cell homeostatic proliferation promotes a redox state that drives metabolic and epige...
https://doi.org/10.1089/ars.2021.0078
Antioxidants & Redox Signaling; Budd RC, Scharer CD et. al.

Jul 31st, 2021 - Numerous abnormalities in T cells have been described in patients with systemic lupus erythematosus (SLE), including lymphopenia, DNA demethylation, expression of endogenous retroviruses, increased cell death, enlarged mitochondria, production of ...

Anti-dsDNA Antibodies Increase the Cardiovascular Risk in Systemic Lupus Erythematosus ...
https://doi.org/10.1161/ATVBAHA.121.315928
Arteriosclerosis, Thrombosis, and Vascular Biology; Patiño-Trives AM, Pérez-Sánchez C et. al.

Jul 30th, 2021 - Systemic lupus erythematosus (SLE) is associated to boosted atherosclerosis development and a higher cardiovascular disease risk. This study aimed to delineate the role of anti-double stranded DNA (anti-dsDNA) antibodies on the molecular profile a...

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Guidelines  11 results

The significance of the low sex ratios of offspring and of sibs of probands with system...
https://doi.org/10.1016/j.earlhumdev.2019.104871
Early Human Development; James WH, Grech V

Sep 8th, 2019 - There is good evidence that there are significantly low sex ratios (proportions male) in the offspring of patients with some immune diseases e.g. systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). There is also strong evidence that ...

2019 update of the EULAR recommendations for the management of systemic lupus erythemat...
https://doi.org/10.1136/annrheumdis-2019-215089
Annals of the Rheumatic Diseases; Fanouriakis A, Kostopoulou M et. al.

Mar 31st, 2019 - Our objective was to update the EULAR recommendations for the management of systemic lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic literature review (01/2007-12/2017), followed by modified Delphi method, to f...

First Latin American clinical practice guidelines for the treatment of systemic lupus e...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225798
Annals of the Rheumatic Diseases; Pons-Estel BA, Bonfa E et. al.

Jul 27th, 2018 - Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therap...

The British Society for Rheumatology guideline for the management of systemic lupus ery...
https://doi.org/10.1093/rheumatology/kex291
Rheumatology (Oxford, England); Gordon C, Amissah-Arthur MB et. al.

Oct 14th, 2017 - The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults: Executive Summary.|2017|Gordon C,Amissah-Arthur MB,Gayed M,Brown S,Bruce IN,|diagnosis,immunology,therapy,

The British Society for Rheumatology guideline for the management of systemic lupus ery...
https://doi.org/10.1093/rheumatology/kex286
Rheumatology (Oxford, England); Gordon C, Amissah-Arthur MB et. al.

Oct 14th, 2017 - The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults.|2017|Gordon C,Amissah-Arthur MB,Gayed M,Brown S,Bruce IN,|diagnosis,therapy,standards,standards,

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Drugs  317 results see all →

Clinicaltrials.gov  234 results

Comparative Autoantibody and Immunologic Cell Marker Study
https://clinicaltrials.gov/ct2/show/NCT02422875

May 6th, 2020 - Systemic lupus erythematosus (SLE) is an autoimmune disease (in autoimmune illness, the immune system in the body attacks it's own cells, leading to illness). It is not completely understood how this disease develops in the body. In a normal perso...

A Study to Evaluate the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-079 in Combination With Standard Background Therapy in Participants With Moderate to Severe Systemic Lupus Er...
https://clinicaltrials.gov/ct2/show/NCT03724916

May 1st, 2020 - 29-Apr-2020 Enrollment of new patients into this study has been paused due to the COVID-19 situation. The duration of this pause is dependent on the leveling and control of the COVID-19 pandemic. TAK-079 is being tested in a study population with ...

Study of Systemic Lupus Erythematosus
https://clinicaltrials.gov/ct2/show/NCT00001372

Apr 29th, 2020 - This research protocol will evaluate subjects with systemic lupus erythematosus (SLE) and their relatives to study the pathogenesis and natural history of the disease and the mechanisms leading to enhanced organ damage. Patients will be evaluated ...

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
https://clinicaltrials.gov/ct2/show/NCT02418442

Apr 29th, 2020 - The original Childhood Arthritis & Rheumatology Research Alliance (CARRA) Registry (Protocol Number: CRNT_REGST01) was first established in 2010 to advance alliance infrastructure, facilitate expanded clinical and translational pediatric research,...

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders
https://clinicaltrials.gov/ct2/show/NCT00055055

Apr 27th, 2020 - Most autoimmune diseases are thought to develop as a result of chronic immune activation and dysregulation after selected environmental exposures in genetically susceptible individuals. Current evidence suggests that the adult and juvenile forms o...

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News  834 results

SLE Neuropsych Event Etiology Helps Define Predictors, Outcomes
https://www.medscape.com/viewarticle/954560

Jul 9th, 2021 - Different kinds of neuropsychiatric (NP) events in patients with systemic lupus erythematosus (SLE) have substantial variability in their occurrence, resolution, and recurrence over time, as well as in their predictors, according to new research f...

BEAT-LUPUS: Belimumab After Rituximab Delays Severe Flares
https://www.medscape.com/viewarticle/952411

Jun 3rd, 2021 - Using belimumab after rituximab to treat patients with systemic lupus erythematosus (SLE) refractory to conventional therapy not only significantly decreased levels of serum IgG anti-dsDNA antibody levels but also prolonged the time before severe ...

Rituximab Benefits Seen in Neuropsychiatric Lupus
https://www.medscape.com/viewarticle/950242

Apr 29th, 2021 - Patients with neuropsychiatric manifestations of systemic lupus erythematosus (NPSLE) seem to benefit from rituximab (Rituxan) therapy, according to data from the British Isles Lupus Assessment Group Biologics Register (BILAG-BR). Indeed, the perc...

Relapsing Lupus Nephritis and Cutaneous Vasculitis: A Race to Contain B Cells
https://www.medscape.com/viewarticle/949863

Apr 28th, 2021 - This article originally appeared on the Hospital for Special Surgery's website. Case Report A 45-year-old woman with a history of systemic lupus erythematosus (SLE) since 2006 came to the Hospital for Special Surgery in 2014 for continued manageme...

Most Patients With Chronic Inflammatory Diseases Have Sufficient Response to COVID-19 Vaccination
https://www.medscape.com/viewarticle/949715

Apr 22nd, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Although most patients with chronic inflammatory diseases mounted immune responses after two doses of mRNA-based COVID-19 vaccines, glucocorticoid...

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Patient Education  6 results see all →