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About 51,698 results

ALLMedicine™ Systemic Lupus Erythematosus Center

Research & Reviews  24,885 results

Anti-phospholipid syndrome leading to digital ischaemia and rare organ complications in...
https://doi.org/10.1007/s10067-020-05399-4
Clinical Rheumatology; Chatterjee S, Pauling JD

Sep 22nd, 2020 - Antiphospholipid syndrome (APS) is an acquired, autoimmune thrombophilia that can occur as a primary disorder (with no associated disease) or secondary to infection, medication usage and autoimmune rheumatic diseases (ARDs). The association betwee...

Toxicity of chloroquine and hydroxychloroquine following therapeutic use or overdose.
https://doi.org/10.1080/15563650.2020.1817479
Clinical Toxicology (Philadelphia, Pa.); Doyno C, Sobieraj DM et. al.

Sep 22nd, 2020 - While chloroquine, a derivative of quinine, has been used as an antimalarial for 70 years, hydroxychloroquine is now used to treat conditions such as rheumatoid arthritis and systemic lupus erythematosus. In 2020, hydroxychloroquine (and to a less...

Frequency of Polyautoimmunity in Patients With Rheumatoid Arthritis and Systemic Lupus ...
https://doi.org/10.1097/RHU.0000000000001574
Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases; Ordoñez-Cañizares MC, Mena-Vázquez N et. al.

Sep 21st, 2020 - To describe the frequency of polyautoimmunity and multiple autoimmune syndrome in patients with rheumatoid arthritis (RA) and patients with systemic lupus erythematosus (SLE). This was a cross-sectional observational study of patients with RA, SLE...

Absence of neuronal autoantibodies in neuropsychiatric systemic lupus erythematosus.
https://doi.org/10.1002/ana.25908
Annals of Neurology; Varley JA, Andersson M et. al.

Sep 20th, 2020 - This study aimed to characterise both neuronal autoantibodies and levels of IFNα, two proposed causative agents in neuropsychiatric systemic lupus erythematosus (NPSLE). CSF and plasma from 35 SLE patients (15 with NPSLE) showed no antibodies agai...

Overexpression of FcγRIIB regulates downstream protein phosphorylation and suppresses B...
https://doi.org/10.3892/ijmm.2020.4698
International Journal of Molecular Medicine; Sheng L, Cao X et. al.

Sep 18th, 2020 - The present study aimed to examine the effects of FcγRIIB on systemic lupus erythematosus (SLE) and to investigate the underlying mechanisms. For this purpose, lentiviral vector carrying the membrane‑bound type FcγRIIB gene (mFcγRIIB lentivirus) a...

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Guidelines  79 results

Fasting Triglycerides & Glucose Index: A Useful Screening Test for Assessing Insulin Resistance in Patients Diagnosed with Rheumatoid Arthritis & Systemic Lupus Erythematosus
https://dmsjournal.biomedcentral.com/articles/10.1186/s13098-019-0495-x
Diabetology & Metabolic Syndrome; Contreras-Haro B,et al

Nov 26th, 2019 - Insulin resistance (IR) is frequently observed in patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). In clinical practice, IR assessment is limited to a low proportion of patients due to cost and equipment and technical...

Sjögren’s Syndrome in Systemic Lupus Erythematosus - a Subset Characterized by a Systemic Inflammatory State
http://www.jrheum.org/content/early/2019/09/11/jrheum.190250
J Rheumatology; Ruacho G,et al

Sep 20th, 2019 - Secondary Sjögren’s syndrome (SLE-sSS) is an often-neglected subset of patients with Systemic lupus erythematosus (SLE). Furthermore, primary Sjögren’s syndrome overlaps and can be difficult to delineate from SLE. To shed light on the SLE-sSS subs...

The significance of the low sex ratios of offspring and of sibs of probands with system...
https://doi.org/10.1016/j.earlhumdev.2019.104871
Early Human Development; James WH, Grech V

Sep 7th, 2019 - There is good evidence that there are significantly low sex ratios (proportions male) in the offspring of patients with some immune diseases e.g. systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). There is also strong evidence that ...

Machine learning approaches to predict lupus disease activity from gene expression data
https://www.nature.com/articles/s41598-019-45989-0
Scientific Reports; Kegerreis,B.,et al

Jul 2nd, 2019 - The integration of gene expression data to predict systemic lupus erythematosus (SLE) disease activity is a significant challenge because of the high degree of heterogeneity among patients and study cohorts, especially those collected on different...

Time in remission and low disease activity state (LDAS) are associated with a better quality of life in patients with systemic lupus erythematosus: results from LUMINA (LXXIX), a multiethnic, multi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560976/
RMD Open;

May 22nd, 2019 - Aims To determine whether the proportion of time systemic lupus erythematosus patients achieve remission/low disease activity state (LDAS) is associated with a better quality of life (QoL). Patients and methods Patients from a well-established mu...

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Drugs  27 results see all →

Clinicaltrials.gov  25,437 results

Anti-phospholipid syndrome leading to digital ischaemia and rare organ complications in...
https://doi.org/10.1007/s10067-020-05399-4
Clinical Rheumatology; Chatterjee S, Pauling JD

Sep 22nd, 2020 - Antiphospholipid syndrome (APS) is an acquired, autoimmune thrombophilia that can occur as a primary disorder (with no associated disease) or secondary to infection, medication usage and autoimmune rheumatic diseases (ARDs). The association betwee...

Toxicity of chloroquine and hydroxychloroquine following therapeutic use or overdose.
https://doi.org/10.1080/15563650.2020.1817479
Clinical Toxicology (Philadelphia, Pa.); Doyno C, Sobieraj DM et. al.

Sep 22nd, 2020 - While chloroquine, a derivative of quinine, has been used as an antimalarial for 70 years, hydroxychloroquine is now used to treat conditions such as rheumatoid arthritis and systemic lupus erythematosus. In 2020, hydroxychloroquine (and to a less...

Frequency of Polyautoimmunity in Patients With Rheumatoid Arthritis and Systemic Lupus ...
https://doi.org/10.1097/RHU.0000000000001574
Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases; Ordoñez-Cañizares MC, Mena-Vázquez N et. al.

Sep 21st, 2020 - To describe the frequency of polyautoimmunity and multiple autoimmune syndrome in patients with rheumatoid arthritis (RA) and patients with systemic lupus erythematosus (SLE). This was a cross-sectional observational study of patients with RA, SLE...

Absence of neuronal autoantibodies in neuropsychiatric systemic lupus erythematosus.
https://doi.org/10.1002/ana.25908
Annals of Neurology; Varley JA, Andersson M et. al.

Sep 20th, 2020 - This study aimed to characterise both neuronal autoantibodies and levels of IFNα, two proposed causative agents in neuropsychiatric systemic lupus erythematosus (NPSLE). CSF and plasma from 35 SLE patients (15 with NPSLE) showed no antibodies agai...

Overexpression of FcγRIIB regulates downstream protein phosphorylation and suppresses B...
https://doi.org/10.3892/ijmm.2020.4698
International Journal of Molecular Medicine; Sheng L, Cao X et. al.

Sep 18th, 2020 - The present study aimed to examine the effects of FcγRIIB on systemic lupus erythematosus (SLE) and to investigate the underlying mechanisms. For this purpose, lentiviral vector carrying the membrane‑bound type FcγRIIB gene (mFcγRIIB lentivirus) a...

see more →

News  1,253 results

J&J scraps late-stage study testing Stelara for lupus
https://www.reuters.com/article/us-johnson-johnson-study/jj-scraps-late-stage-study-testing-stelara-for-lupus-idUSKBN23X1OX

Jun 26th, 2020 - (Reuters) - Johnson & Johnson’s Janssen unit said on Friday it would discontinue a late-stage study testing its psoriatic arthritis drug Stelara as a treatment for lupus as it was not found to be effective against the auto-immune disease. Systemic...

African Americans with SLE face increased risk of CVD hospitalizations
https://www.mdedge.com/familymedicine/article/219235/acute-coronary-syndromes/african-americans-sle-face-increased-risk-cvd?channel=39313
MDedge Dermatology; Bruce Jancin

Mar 17th, 2020 - PHOENIX – African Americans with systemic lupus erythematosus are more likely to experience recurrent hospitalizations for cardiovascular disease, compared with other racial/ethnic groups, results from a single-state registry study found. Doug Bru.

High CV event risk seen in SLE patients with ACC/AHA-defined hypertension
https://www.mdedge.com/internalmedicine/article/219138/lupus-connective-tissue-diseases/high-cv-event-risk-seen-sle?channel=39313
Andrew D. Bowser

Mar 17th, 2020 - Patients with lupus who have sustained high blood pressure may be at significantly increased risk of cardiovascular events, compared with those patients whose blood pressure is in the range now considered to be normal, results of a retrospective,.

Use of mHealth technology lags in lupus care, research
https://www.mdedge.com/internalmedicine/article/218800/lupus-connective-tissue-diseases/use-mhealth-technology-lags-lupus?channel=39313
Jeff Evans

Mar 11th, 2020 - Mobile health technologies currently available for patients with systemic lupus erythematosus (SLE), particularly mobile health (mHealth) apps, are poor quality and have limited “The use of mobile technologies to support health (mHealth technologi.

Meta-analysis eyes impact of adherence to HCQ among SLE patients
https://www.mdedge.com/internalmedicine/article/216957/lupus-connective-tissue-diseases/meta-analysis-eyes-impact-adherence?channel=290
Doug Brunk

Feb 10th, 2020 - Low serum levels of hydroxychloroquine (HCQ) among patients with systemic lupus erythematosus are associated with a threefold increased likelihood of physician- and patient-reported nonadherence to the medication. In addition, routine monitoring o.

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Patient Education  17 results see all →