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About 10,483 results

ALLMedicine™ Pruritus Center

Research & Reviews  2,810 results

Compound Heterozygous Myosin 5B (Myo5b) Mutation with Early Onset Progressive Cholestas...
https://doi.org/10.1080/15513815.2021.1959690
Fetal and Pediatric Pathology; Vij M, Shah V

Aug 3rd, 2021 - Exome sequencing studies have recently identified novel genes implicated in normal or low GGT pediatric cholestasis including myosin 5B (MYO5B). Case report: We identified novel compound heterozygote mutations in exon 14 and exon 19 of the MYO5B g...

Cutaneous adverse events caused by immune checkpoint inhibitors.
https://doi.org/10.1016/j.jaad.2020.09.054
Journal of the American Academy of Dermatology; Quach HT, Johnson DB et. al.

Aug 2nd, 2021 - Immune checkpoint inhibitors (ICIs) have emerged as active therapies for a variety of cancers. Cutaneous toxicities are common immune-related adverse events and patients will often be referred to dermatologists for evaluation. Cutaneous adverse ev...

Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-...
https://doi.org/10.1016/j.jep.2021.114474
Journal of Ethnopharmacology; Fan P, Yang Y et. al.

Aug 1st, 2021 - Viola yedoensis Makiho (VY, Violaceae) is a well-known medicinal herb in Chinese medicine, which is traditionally used to treat inflammation-related disorders, including allergic skin reactions. Although studies have uncovered its anti-inflammator...

Estrogens influence female itch sensitivity via the spinal gastrin-releasing peptide re...
https://doi.org/10.1073/pnas.2103536118
Proceedings of the National Academy of Sciences of the Un... Takanami K, Uta D et. al.

Jul 28th, 2021 - There are sex differences in somatosensory sensitivity. Circulating estrogens appear to have a pronociceptive effect that explains why females are reported to be more sensitive to pain than males. Although itch symptoms develop during pregnancy in...

Prurigo pigmentosa following a ketogenic diet: a case report.
https://doi.org/10.1038/s41430-021-00987-2 10.1007/s40257-015-0154-4 10.1016/j.jdin.2021.03.003 10.1016/j.jdcr.2019.03.011 10.1001/jamadermatol.2015.0247 10.1038/ejcn.2013.116
European Journal of Clinical Nutrition; Sun HY, Sebaratnam DF

Jul 25th, 2021 - A 19-year-old female of South Asian descent presented with a three-day history of pruritic, clustered papules and vesicles on her abdomen, associated with significant pruritus and intermittent pain. She commenced a ketogenic diet four days prior t...

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Guidelines  6 results

Diagnosis and Management of Vulvar Skin Disorders: ACOG Practice Bulletin Summary, Numb...
https://doi.org/10.1097/AOG.0000000000003945
Obstetrics and Gynecology;

Jun 27th, 2020 - Vulvar skin disorders include a variety of inflammatory conditions of the vulva that also may affect the extragenital area. Pruritus and pain are two of the most common presenting symptoms in vulvar clinics (). Vulvovaginal symptoms often are chro...

Diagnosis and Management of Vulvar Skin Disorders: ACOG Practice Bulletin, Number 224.
https://doi.org/10.1097/AOG.0000000000003944
Obstetrics and Gynecology;

Jun 27th, 2020 - Vulvar skin disorders include a variety of inflammatory conditions of the vulva that also may affect the extragenital area. Pruritus and pain are two of the most common presenting symptoms in vulvar clinics (). Vulvovaginal symptoms often are chro...

British Association of Dermatologists' guidelines for the investigation and management ...
https://doi.org/10.1111/bjd.16117
The British Journal of Dermatology; Millington GWM, Collins A et. al.

Jan 24th, 2018 - British Association of Dermatologists' guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018.|2018|Millington GWM,Collins A,Lovell CR,Leslie TA,Yong ASW,|administration & dosage,co...

Clinical recommendation: pediatric lichen sclerosus.
https://doi.org/10.1016/j.jpag.2013.11.004
Journal of Pediatric and Adolescent Gynecology; Bercaw-Pratt JL, Boardman LA et. al.

Mar 8th, 2014 - Lichen sclerosus is a chronic inflammatory condition affecting the anogenital region that may present in the prepubertal or adolescent patient. Clinical presentations include significant pruritus, labial adhesions, and loss of pigmentation. Treatm...

Asia-Pacific consensus recommendations for endoscopic and interventional management of ...
https://doi.org/10.1111/jgh.12128
Journal of Gastroenterology and Hepatology; Rerknimitr R, Angsuwatcharakon P et. al.

Jan 29th, 2013 - Hilar cholangiocarcinoma (HCCA) is one of the most common types of hepatobiliary cancers reported in the world including Asia-Pacific region. Early HCCA may be completely asymptomatic. When significant hilar obstruction develops, the patient prese...

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Drugs  694 results see all →

Clinicaltrials.gov  178 results

Study Evaluating Efficacy and Safety of PF-04965842 and Dupilumab in Adult Subjects With Moderate to Severe Atopic Dermatitis on Background Topical Therapy
https://clinicaltrials.gov/ct2/show/NCT03720470

Apr 22nd, 2020 - B7451029 is a Phase 3 study to investigate PF-04965842 in adult patients who have moderate to severe atopic dermatitis and use background topical therapy. The efficacy of two dosage strengths of PF-04965842, 100 mg and 200 mg taken orally once dai...

A Study Examining the Medication Apremilast as Treatment for Chronic Itch
https://clinicaltrials.gov/ct2/show/NCT03239106

Apr 20th, 2020 - There is no FDA-approved medication for chronic idiopathic pruritus (CIP). Apremilast has demonstrated notable activity and is approved for treatment in other pruritic inflammatory skin conditions such as psoriasis. The drug is currently being inv...

Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies
https://clinicaltrials.gov/ct2/show/NCT02485704

Mar 19th, 2020 - This is a double blind, two-arm, 28-day, placebo-controlled study with approximately 120 infested "index" subjects randomized 1:1 to Natroba™ or Placebo. All members of a household (no more than 6 individuals) with a suspected "index" subject must...

The Ruxo-BEAT Trial in Patients With High-risk Polycythemia Vera or High-risk Essential Thrombocythemia
https://clinicaltrials.gov/ct2/show/NCT02577926

Mar 10th, 2020 - Polycythemia vera (PV) and essential thrombocythemia (ET) are classical Philadelphia-negative myeloproliferative neoplasms (MPN) that are characterized by an excess of cells in the peripheral blood, clonal bone marrow hyperplasia, and extramedulla...

Comparative Analysis of Filmed Sequences for the Assessment of Discomfort in Atopic Dermatitis of Infants Under 6 Months of Age
https://clinicaltrials.gov/ct2/show/NCT03684343

Mar 5th, 2020 - Atopic dermatitis (AD) is an frequent chronic and itchy inflammatory dermatitis which concern about 20% of pediatric population with a revelation usually toward 3-6 months of live. However, there are very few data about the prevalence of pruritus ...

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News  496 results

FDA Approves StrataGraft for Deep Skin Burns
https://www.medscape.com/viewarticle/953353

Jun 18th, 2021 - The US Food and Drug Administration (FDA) has approved a novel regenerative therapy that could be an alternative to autografting for treating adults with severe burns. The new treatment, StrataGraft, is a bilayer tissue engineered to mimic the epi...

A Farmer With Diffuse Pruritus and a Suntan That Won't Fade
https://reference.medscape.com/viewarticle/952272

Jun 8th, 2021 - Editor's Note: The Case Challenge series includes difficult-to-diagnose conditions, some of which are not frequently encountered by most clinicians but are nonetheless important to accurately recognize. Test your diagnostic and treatment skills us...

Five Clinical Highlights From AACR Annual Meeting (Part 1)
https://www.medscape.com/viewarticle/949646

Apr 21st, 2021 - The American Association for Cancer Research (AACR) Annual Meeting 2021 is mostly a jamboree of basic research and early-stage clinical study presentations, but some of the presentations feature clinical data that can change oncology practice. Thi...

AAP Issues Recommendations for Common Dermatologic Problems
https://www.medscape.com/viewarticle/949207

Apr 13th, 2021 - The American Academy of Pediatrics recently issued five recommendations for the most common dermatologic problems in primary care pediatrics. Topics include diagnostic and management strategies for a variety of conditions, including atopic dermati...

Difelikefalin Safe, Effective for Kidney Disease-Associated Pruritus
https://www.medscape.com/viewarticle/949033

Apr 9th, 2021 - Difelikefalin, an investigational intravenous (IV) drug for treating itch (pruritus) in patients with end-stage renal disease on hemodialysis, was safe and effective in two parallel pivotal trials in which 796 patients on dialysis received the dru...

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Patient Education  9 results see all →