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About 13,498 results

ALLMedicine™ Pruritus Center

Research & Reviews  5,573 results

Safety considerations for the management of cholestatic itch.
https://doi.org/10.1080/14740338.2021.1915984
Expert Opinion on Drug Safety; Trivella J, Levy C

Apr 10th, 2021 - Pruritus is a disabling symptom common to cholestatic liver disorders. Its pathophysiology has not been completely elucidated and although multiple mediators have been identified, only lysophosphatidic acid (LPA) and its synthetizing enzyme autota...

Treatment of Chronic Pruritus With Medical Marijuana.
https://doi.org/10.1001/jamadermatol.2021.1194
JAMA Dermatology; Roh YS, Sutaria N et. al.

Apr 9th, 2021 - Treatment of Chronic Pruritus With Medical Marijuana.|2021|Roh YS,Sutaria N,Biles NF,Kwatra SG,|

Commentary on: Synergistic Effect on Botulinum Toxin Type-A and Triamcinolone Alleviate...
https://doi.org/10.1093/asj/sjab063
Aesthetic Surgery Journal; Gold MH

Apr 6th, 2021 - Commentary on: Synergistic Effect on Botulinum Toxin Type-A and Triamcinolone Alleviates Scar Pruritus by Modulating Epidermal Hyperinnervation: A Preliminary Report.|2021|Gold MH,|

Epithelia-sensory neuron crosstalk underlies cholestatic itch induced by lysophosphatid...
https://doi.org/10.1053/j.gastro.2021.03.049
Gastroenterology Chen Y, Wang ZL et. al.

Apr 5th, 2021 - Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of anti-pruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus. Pruritogenicity of...

Targeted inhibition of EPAS1-driven IL-31 production by a small-molecule compound.
https://doi.org/10.1016/j.jaci.2021.03.029
The Journal of Allergy and Clinical Immunology; Kamikaseda Y, Uruno T et. al.

Apr 5th, 2021 - IL-31 is a major pruritogen associated with atopic dermatitis (AD). Although a specific antibody for IL-31 receptor has been shown to alleviate pruritus in patients with AD, therapeutic approaches to inhibit IL-31 production remain unexploited. IL...

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Guidelines  19 results

Society for Maternal-Fetal Medicine Consult Series #53: Intrahepatic cholestasis of pre...
https://doi.org/10.1016/j.ajog.2020.11.002
American Journal of Obstetrics and Gynecology; , Lee RH et. al.

Nov 16th, 2020 - Intrahepatic cholestasis of pregnancy is a hepatic disorder characterized by pruritus and an elevation in serum bile acid levels. Although intrahepatic cholestasis of pregnancy poses little risk for women, this condition carries a significant risk...

Diagnosis and Management of Vulvar Skin Disorders: ACOG Practice Bulletin Summary, Numb...
https://doi.org/10.1097/AOG.0000000000003945
Obstetrics and Gynecology;

Jun 26th, 2020 - Vulvar skin disorders include a variety of inflammatory conditions of the vulva that also may affect the extragenital area. Pruritus and pain are two of the most common presenting symptoms in vulvar clinics (). Vulvovaginal symptoms often are chro...

Diagnosis and Management of Vulvar Skin Disorders: ACOG Practice Bulletin, Number 224.
https://doi.org/10.1097/AOG.0000000000003944
Obstetrics and Gynecology;

Jun 26th, 2020 - Vulvar skin disorders include a variety of inflammatory conditions of the vulva that also may affect the extragenital area. Pruritus and pain are two of the most common presenting symptoms in vulvar clinics (). Vulvovaginal symptoms often are chro...

Nail Changes Following a Viral Infection: Photo Quiz
https://www.aafp.org/afp/2019/1015/p497.html
American Family Physician;

Oct 14th, 2019 - A seven-year-old boy presented with abnormal growth of his fingernails that began two weeks prior. He had no other symptoms, including pain or pruritus on his hands or around his nails. He did not have fevers, chills, nausea, vomiting, or change i...

Pruritus (PDQ®)–Health Professional Version
https://www.cancer.gov/about-cancer/treatment/side-effects/skin-nail-changes/pruritus-hp-pdq

Aug 12th, 2019 - Pruritus (itching of the skin) can be a complication of cancer or its treatment. Get detailed information about the etiology, assessment, and interventions for pruritus in this summary for clinicians.

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Drugs  747 results see all →

Clinicaltrials.gov  6,589 results

Safety considerations for the management of cholestatic itch.
https://doi.org/10.1080/14740338.2021.1915984
Expert Opinion on Drug Safety; Trivella J, Levy C

Apr 10th, 2021 - Pruritus is a disabling symptom common to cholestatic liver disorders. Its pathophysiology has not been completely elucidated and although multiple mediators have been identified, only lysophosphatidic acid (LPA) and its synthetizing enzyme autota...

Treatment of Chronic Pruritus With Medical Marijuana.
https://doi.org/10.1001/jamadermatol.2021.1194
JAMA Dermatology; Roh YS, Sutaria N et. al.

Apr 9th, 2021 - Treatment of Chronic Pruritus With Medical Marijuana.|2021|Roh YS,Sutaria N,Biles NF,Kwatra SG,|

Difelikefalin Safe, Effective for Kidney Disease-Associated Pruritus
https://www.medscape.com/viewarticle/949033

Apr 8th, 2021 - Difelikefalin, an investigational intravenous (IV) drug for treating itch (pruritus) in patients with end-stage renal disease on hemodialysis, was safe and effective in two parallel pivotal trials in which 796 patients on dialysis received the dru...

Hydroxyzine pamoate - hydroxyzine pamoate capsule-PD-Rx Pharmaceuticals, Inc.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=98a1c161-5728-4626-a6b0-5414935e4eef

Apr 8th, 2021 - For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria and ...

Commentary on: Synergistic Effect on Botulinum Toxin Type-A and Triamcinolone Alleviate...
https://doi.org/10.1093/asj/sjab063
Aesthetic Surgery Journal; Gold MH

Apr 6th, 2021 - Commentary on: Synergistic Effect on Botulinum Toxin Type-A and Triamcinolone Alleviates Scar Pruritus by Modulating Epidermal Hyperinnervation: A Preliminary Report.|2021|Gold MH,|

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News  563 results

Difelikefalin Safe, Effective for Kidney Disease-Associated Pruritus
https://www.medscape.com/viewarticle/949033

Apr 8th, 2021 - Difelikefalin, an investigational intravenous (IV) drug for treating itch (pruritus) in patients with end-stage renal disease on hemodialysis, was safe and effective in two parallel pivotal trials in which 796 patients on dialysis received the dru...

Fast Five Quiz: Atopic Dermatitis and Type 2 Cytokines
https://reference.medscape.com/viewarticle/944891

Mar 2nd, 2021 - Atopic dermatitis is a chronic inflammatory skin condition characterized by pruritus, erythema, lichenification, and excoriation. These clinical manifestations result in an impaired quality of life, especially in patients with moderate to severe d...

Dupilumab Curbed Itch Intensity, Frequency in Children With Severe Eczema
https://www.medscape.com/viewarticle/943807

Jan 7th, 2021 - Dupilumab treatment with concomitant topical corticosteroids provided rapid and sustained improvement in itch intensity and frequency in children aged 6-11 years with severe atopic dermatitis. Dr Gil Yosipovitch The findings come from a post hoc a...

Study: Doctors Underreport Side Effects of Breast Irradiation
https://www.medscape.com/viewarticle/943289

Dec 28th, 2020 - There is a substantial mismatch between patient and physician reports of toxicity during radiotherapy for breast cancer, according to an analysis of nearly 10,000 U.S. patients. Researchers assessed physician underrecognition of four key symptoms ...

Antihistamine Prescribing for AD Varies by Specialty
https://www.medscape.com/viewarticle/942699

Dec 14th, 2020 - Dermatologists are more likely than are nondermatologists to follow practice guidelines when prescribing antihistamines to treat pruritus associated with atopic dermatitis (AD), according to an analysis of a national database.   The American Acade...

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Patient Education  7 results see all →