About 11,588 results

ALLMedicine™ Pruritus Center

Research & Reviews  3,004 results

The Genomic and Phenotypic Landscape of Ichthyosis: An Analysis of 1000 Kindreds.
JAMA Dermatology; Sun Q, Burgren NM et. al.

Dec 2nd, 2021 - Ichthyoses are clinically and genetically heterogeneous disorders characterized by scaly skin. Despite decades of investigation identifying pathogenic variants in more than 50 genes, clear genotype-phenotype associations have been difficult to est...

Meet the expert: Topical management of vulvar dermatoses.
Journal of Geriatric Oncology; Jakuboski SH, Noor SJ

Nov 27th, 2021 - Vulvar dermatoses are often debilitating chronic skin conditions associated with pain and pruritus. In oncologic patients, cancer treatments can precipitate and exacerbate vulvar dermatoses. Cytotoxic chemotherapy, hormonal therapies, and local pe...

Intralesional Biologics for Inflammatory Dermatoses: A Systematic Review.
Dermatologic Therapy; Seivright JR, Villa NM et. al.

Nov 27th, 2021 - Biologic medications are systemic therapeutic options for inflammatory dermatoses. Local forms of administration are less well-studied. To provide a summary of intralesional (IL) administration of biologics for various non-malignant inflammatory d...

Allergic vulvovaginitis: a systematic literature review.
https://doi.org/10.1007/s00404-021-06332-z 10.1016/S0001-7310(08)74655-6 10.1097/01.AOG.0000239103.67452.1a 10.1097/AOG.0000000000000551 10.1136/adc.81.1.64 10.1007/s12519-016-0078-y 10.1007/s11908-017-0558-9 10.1136/sti.2003.005132 10.4103/0253-7184.180286 10.1097/DER.0000000000000339 10.1016/S1081-1206(10)62527-6 10.1159/000082570 10.1007/s00404-005-0732-4 10.1097/GRF.0000000000000094 10.1007/s00105-014-3561-1 10.1371/journal.pmed.1000097 10.5414/DBP52033 10.2500/108854191779011828 10.1016/0002-9378(76)90634-7 10.1111/all.12724 10.1111/j.1365-2222.1974.tb01382.x 10.1007/s00105-003-0672-5 10.1016/j.anai.2018.09.255 10.1016/j.jaip.2017.04.008 10.1111/j.1600-0536.1994.tb00720.x 10.1097/01.AOG.0000285480.15136.d1 10.1016/0091-6749(93)90328-D 10.1034/j.1398-9995.1999.00181.x 10.1016/s0015-0282(16)42736-6 10.1177/000456329403100317 10.3109/02770908809073201 10.1111/j.1365-2133.2012.10956.x 10.1016/j.alit.2018.08.003 10.1016/j.anai.2013.01.001 10.1016/S1081-1206(10)61463-9 10.1097/00006254-198110010-00022 10.1186/s13223-019-0335-4 10.1016/S0091-6749(96)80208-9 10.1111/j.1600-0536.1989.tb03173.x 10.1111/j.1600-0536.1990.tb05104.x 10.1016/j.jaip.2020.04.067 10.1111/j.1447-0756.2007.00578.x 10.1016/s0301-0546(01)79047-7 10.1034/j.1398-9995.1999.00911.x 10.1016/S0091-6749(95)70189-3 10.1016/0002-9378(89)90978-2 10.1016/S0091-6749(98)70366-5 10.1016/j.anai.2015.04.014 10.1111/all.13961 10.2500/ar.2015.6.0113 10.1111/j.1398-9995.2009.02076.x 10.1111/j.1365-2249.2005.02891.x 10.1016/S1081-1206(10)62804-9 10.1016/0002-9378(90)90380-P 10.1002/j.1879-3479.1980.tb00528.x 10.1016/0091-6749(88)90909-8 10.1016/j.ijgo.2007.08.024 10.1590/S0104-42302003000400037 10.1128/iai.18.1.257-259.1977 10.1080/02681218980000081 10.1016/j.clinthera.2019.04.010 10.1016/S0091-6749(96)70259-2 10.1007/s00404-016-4081-2 10.1016/j.jaci.2007.10.008 10.1186/2045-7022-3-3 10.1093/infdis/164.2.396 10.1097/00003081-199303000-00017
Archives of Gynecology and Obstetrics; Oliveira AS, Rolo J et. al.

Nov 27th, 2021 - Despite the vaginal mucosa is able to respond to allergenic stimuli, vaginal allergic responses have been under investigated in clinical practice. Thus, we aimed to identify the most frequent etiological agents responsible for vulvovaginal allergi...

Polidocanol Sclerotherapy in Pyogenic Granulomas.
Dermatologic Surgery : Official Publication for American ... Khurana A, Mathachan SR

Nov 25th, 2021 - Polidocanol is a safe sclerosing agent with anesthetic properties and minimal skin toxicity. To evaluate the efficacy, safety, and recurrence rates with polidocanol sclerotherapy in the treatment of pyogenic granulomas (PGs). Thirty-nine patients ...

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Guidelines  6 results

Diagnosis and Management of Vulvar Skin Disorders: ACOG Practice Bulletin Summary, Numb...
Obstetrics and Gynecology;

Jun 27th, 2020 - Vulvar skin disorders include a variety of inflammatory conditions of the vulva that also may affect the extragenital area. Pruritus and pain are two of the most common presenting symptoms in vulvar clinics (). Vulvovaginal symptoms often are chro...

Diagnosis and Management of Vulvar Skin Disorders: ACOG Practice Bulletin, Number 224.
Obstetrics and Gynecology;

Jun 27th, 2020 - Vulvar skin disorders include a variety of inflammatory conditions of the vulva that also may affect the extragenital area. Pruritus and pain are two of the most common presenting symptoms in vulvar clinics (). Vulvovaginal symptoms often are chro...

British Association of Dermatologists' guidelines for the investigation and management ...
The British Journal of Dermatology; Millington GWM, Collins A et. al.

Jan 24th, 2018 - British Association of Dermatologists' guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018.|2018|Millington GWM,Collins A,Lovell CR,Leslie TA,Yong ASW,|administration & dosage,co...

Clinical recommendation: pediatric lichen sclerosus.
Journal of Pediatric and Adolescent Gynecology; Bercaw-Pratt JL, Boardman LA et. al.

Mar 8th, 2014 - Lichen sclerosus is a chronic inflammatory condition affecting the anogenital region that may present in the prepubertal or adolescent patient. Clinical presentations include significant pruritus, labial adhesions, and loss of pigmentation. Treatm...

Asia-Pacific consensus recommendations for endoscopic and interventional management of ...
Journal of Gastroenterology and Hepatology; Rerknimitr R, Angsuwatcharakon P et. al.

Jan 29th, 2013 - Hilar cholangiocarcinoma (HCCA) is one of the most common types of hepatobiliary cancers reported in the world including Asia-Pacific region. Early HCCA may be completely asymptomatic. When significant hilar obstruction develops, the patient prese...

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Drugs  651 results see all →

Clinicaltrials.gov  238 results

A Study Investigating the Effect of EDP1815 in the Treatment of Mild, Moderate and Severe Atopic Dermatitis

Nov 24th, 2021 - Atopic dermatitis (atopic eczema) is a very common type of skin disease. It typically causes red, dry, and itchy skin and may have a significant impact on quality of life. Rashes may appear on the arms and behind the knees, or anywhere else on the...

Interventional Study to Evaluate the Appearance of Surgical Scars After Laser Therapy

Nov 22nd, 2021 - In dermatology, the use of Light Amplification by Stimulated Emission of Radiation (laser) has revolutionized the management of various conditions including angiomas, vitiligo, wrinkles, and scars. (Omi, 2014 and Chapas, 2008) Scars result from su...

Evaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults.

Nov 22nd, 2021 - Pain of VOC in sickle-cell patients seen in the emergency department (ED) is severe. Analgesia is a therapeutic emergency based on intravenous (IV) morphine titration. However, for technical reasons (patient flow in ED, difficult venous access) th...

Clinical Study on the Immune Program of Recombinant Novel Coronavirus(COVID-19) Vaccine (CHO Cell)

Nov 22nd, 2021 - Overall design:In this study, a single-arm design was used to evaluate the immunogenicity and safety of recombinant novel coronavirus vaccine (CHO cells) inoculated at 0,1,6 months in persons aged 18 years and older. Intervention: A total of 300 s...

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)

Nov 19th, 2021 - The purpose of this extension study is to determine the long-term safety and tolerability of an investigational treatment (LUM001 also known as Maralixibat) in children with ALGS who have completed participation in a core LUM001 treatment protocol...

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News  731 results

Certain opioids hold promise for treating itch
Doug Brunk

Nov 24th, 2021 - Certain opioids are proving to be effective in treating a variety of itch conditions, according to Brian S. Kim, MD.

FDA OKs PD-1 Inhibitor for Adjuvant Treatment of Kidney Cancer

Nov 18th, 2021 - The FDA approved pembrolizumab (Keytruda) for the adjuvant treatment of renal cell carcinoma (RCC) for patients who have an intermediate-high or high risk of recurrence following nephrectomy, or following nephrectomy and resection of metastatic le...

SL-172154 Shows Favorable Tolerability in Platinum-Resistant Ovarian Cancer

Nov 17th, 2021 - The investigative agent SL-172154 (SIRPα-Fc-CD40L) was found to be well tolerated, with no dose-limiting toxicities (DLTs) observed, in patients with platinum-resistant ovarian cancer, according to findings from a phase 1 dose-escalation trial pre...

Year in Review: HIV

Nov 12th, 2021 - Long-acting therapies headlined a year of continued drug development, both in the treatment and prevention of HIV. Meanwhile, CDC recommended a third dose of a COVID-19 mRNA vaccine for certain patients living with advanced or untreated HIV to boo...

Linear Violaceous Papules in a Child
Aaron Tisack, MD, Chelsea Luther, MD et. al.

Nov 5th, 2021 - The Diagnosis: Linear Lichen Planus The patient was clinically diagnosed with linear lichen planus and was started on betamethasone dipropionate ointment 0. 05% applied once daily with improvement in both the pruritus and appearance at 4-month foll.

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Patient Education  5 results see all →