About 10,838 results

ALLMedicine™ Purpura Center

Research & Reviews  3,264 results

Recent advances in therapeutic options for rare hemostatic disorders: selected poster e...
Expert Review of Hematology; Jain N, Oldenburg J et. al.

Jun 25th, 2022 - Hemophilia, von Willebrand disease (VWD), and thrombotic thrombocytopenic purpura (TTP) are rare diseases affecting normal hemostasis. Although they differ in their pathogenesis and clinical manifestation, if left undiagnosed and untreated, all th...

Assessing efficacy and safety of replacement fluids in therapeutic plasma exchange: A s...
Journal of Clinical Apheresis; Kohli R, Geneen LJ et. al.

Jun 22nd, 2022 - The aim of this systematic scoping review is to identify and categorize the outcome measures that have been reported in clinical studies, where therapeutic plasma exchange (TPE) has been used as an intervention in any clinical settings, excluding ...

Severe case of refractory immune thrombocytopenic purpura requiring splenectomy after t...
BMJ Case Reports; Koilpillai S, Dominguez B et. al.

Jun 21st, 2022 - Immune thrombocytopenic purpura (ITP) is an autoimmune disorder caused by autoantibodies against platelet antigens resulting in platelet destruction and inhibition of platelet production. Occasionally, an inciting event such as a virus or vaccinat...

IgA vasculitis with underlying monoclonal IgA gammopathy: innovative therapeutic approa...
https://doi.org/10.1007/s10067-022-06181-4 10.1016/j.revmed.2013.12.004 10.1016/j.autrev.2017.10.009 10.1053/sarh.2000.6988 10.1111/1346-8138.14466 10.1111/jdv.14683 10.1038/sj.leu.2404284 10.1002/art.40178 10.1016/j.autrev.2020.102611 10.1016/j.kint.2016.10.026
Clinical Rheumatology; Hankard A, Ingen-Housz-Oro S et. al.

Jun 18th, 2022 - There is currently no evidence of the possible benefit of plasma cell-targeting therapies (PCTT) in immunoglobulin A (IgA) monoclonal gammopathy (MG) associated with IgA vasculitis (IgAV). We report the outcome of different PCTT regimens in a coho...

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Guidelines  5 results

Oropharyngeal psychogenic purpura.
British Journal of Haematology; Allar BG, Michaelsen K et. al.

Aug 6th, 2020 - Oropharyngeal psychogenic purpura.|2020|Allar BG,Michaelsen K,Gupta A,Bose S,|metabolism,pathology,metabolism,pathology,metabolism,pathology,metabolism,pathology,metabolism,pathology,

European consensus-based recommendations for diagnosis and treatment of immunoglobulin ...
Rheumatology (Oxford, England); Ozen S, Marks SD et. al.

Mar 18th, 2019 - IgA vasculitis (IgAV, formerly known as Henoch-Schönlein purpura) is the most common cause of systemic vasculitis in childhood. To date, there are no internationally agreed, evidence-based guidelines concerning the appropriate diagnosis and treatm...

ACG Clinical Guideline: Treatment of Helicobacter pylori Infection.
The American Journal of Gastroenterology; Chey WD, Leontiadis GI et. al.

Jan 11th, 2017 - Helicobacter pylori (H. pylori) infection is a common worldwide infection that is an important cause of peptic ulcer disease and gastric cancer. H. pylori may also have a role in uninvestigated and functional dyspepsia, ulcer risk in patients taki...

Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and o...
British Journal of Haematology; Scully M, Hunt BJ et. al.

May 26th, 2012 - Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies.|2012|Scully M,Hunt BJ,Benjamin S,Liesner R,Rose P,|diagnosis,pathology,therapy,diagnosis,pathology,therapy,

Guidelines for the diagnosis and management of disseminated intravascular coagulation. ...
British Journal of Haematology; Levi M, Toh CH et. al.

Feb 19th, 2009 - The diagnosis of disseminated intravascular coagulation (DIC) should encompass both clinical and laboratory information. The International Society for Thrombosis and Haemostasis (ISTH) DIC scoring system provides objective measurement of DIC. Wher...

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Drugs  387 results see all →

Clinicaltrials.gov  254 results

Clinical Characteristics and Outcomes of SLE Patients Admitted to Critical Care Unit

Jun 14th, 2022 - Systemic lupus erythematosus (SLE) is a systemic heterogeneous autoimmune disease with a highly variable course and prognosis that many different organs may be affected . It has wide spectrum of clinical presentation that affects all ages and ethn...

Safety and Tolerability of M254 in Healthy Volunteers and Immune Thrombocytopenic Purpura (ITP) Patients

Jun 8th, 2022 - The Part A of the study is currently not accepting healthy volunteers as the recruitment for the part A has completed.

Improvement of Immunologic and Molecular Techniques for the Diagnosis and Follow-up of Patients With Thrombotic Thrombocytopenic Purpura

May 27th, 2022 - The lack of ADAMTS13 is the only biological marker that is specific for aTTP diagnosis8 and the assessment of ADAMTS13 is of clinical importance because it is essential for the rapid differential diagnosis between aTTP and other TMA. Furthermore, ...

.German TTP-Registry (Thrombotic Thrombocytopenic Purpura)

May 24th, 2022 - 1.) Identification of predictive markers for morbidity and mortality in acute TTP and in TTP relapses using a prospective long-term registry and 2.) Investigation of the pathophysiological processes in acute bouts and in remission by recording the...

Plasma microRNA Levels and Some Cytokines Expression in Patients With ITP Primary Immune Thrombocytopenic Purpura (ITP)

May 12th, 2022 - In recent years the critical role of miRNAs has been established in many diseases, including autoimmune disorders. Immune thrombocytopenic purpura (ITP) is a predominant autoimmune disease, in which aberrant expression of miRNAs has been observed,...

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News  409 results

Ulcer on knuckle
MDedge Family Medicine;

May 26th, 2022 - Since the papules were worrisome for vasculitis, 2 punch biopsies were performed on smaller, younger lesions on the hand and 1 was submitted for direct immunofluorescence. Findings revealed a leukocytoclastic vasculitis (LCV) with prominent immuno.

Retiform Purpura on the Legs
Mark C. Marchitto, MD, Liesl Grenier, MD et. al.

May 10th, 2022 - The Diagnosis: Calciphylaxis Histopathology revealed epidermal and dermal necrosis, a perivascular neutrophilic infiltrate, and scattered microcalcifications within small- and medium-sized subcutaneous vessels, consistent with a diagnosis of calci.

24-year-old female presents with a 3-month history of nonpruritic rash
Lynette Xu, Brooke Resh Sateesh, MD

Apr 19th, 2022 - Purpura annularis telangiectodes of Majocchi (PATM) or Majocchi’s disease, is an uncommon subtype of pigmented purpuric dermatosis (PPD) or capillaritis, typically characterized by symmetrical, nonblanching, purpuric, telangiectatic, and atrophic.

A case of cold, purple toes
MDedge Family Medicine;

Apr 14th, 2022 - A punch-biopsy was performed on the left second toe where the erythema was the most intense. It demonstrated classic findings for pernio: superficial and deep perivascular lymphocytic inflammation and papillary dermal edema on the acral surface.

Interstitial Granulomatous Dermatitis as an Adverse Reaction to Vedolizumab
Katherine G. Beuerlein, BS, Elise D. Martin, MD et. al.

Mar 3rd, 2022 - The number of monoclonal antibodies developed for therapeutic use has rapidly expanded over the last decade due to their generally favorable adverse effect (AE) profiles and efficacy. 1 Tumor necrosis factor α inhibitors and general integrin antago.

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Patient Education  16 results see all →