ALLMedicine™ Cholangitis Center

Jan 19th, 2021 - Liver chemistry abnormalities are a frequent manifestation of coronavirus disease 2019 (COVID-19) but are usually transient and resolve with disease resolution. We describe the clinical course and histologic features of 3 adults who developed prol...

Jan 19th, 2021 - The optimal antibiotic therapy duration for cholangitis is unclear. Guideline recommendations vary between 4 and 14 days after biliary drainage. Clinical observations and some evidence however suggest that shorter antibiotic therapy may be suffici...

Jan 19th, 2021 - Primary biliary cholangitis (PBC) is a prototypical organ specific autoimmune disease, mediated by autoreactive T cell attack and destruction of cholangiocytes. Despite the clear role of autoimmunity in PBC, immune-directed therapies have failed t...

Jan 19th, 2021 - Recurrent primary biliary cholangitis (rPBC) occurs in up to 53% of LT recipients transplanted for PBC and negatively impacts long term graft (Hazard ratio 2.01) and patient survival (hazard ratio 1.72)(1). In multiple cohort studies, use of ursod...

Jan 18th, 2021 - Amidst the coronavirus (COVID-19) pandemic, the American Society for Transplant Surgeons has recommended that only urgent liver transplant with deceased donors should occur. However, young pediatric candidates rely on living donors for lifesaving ...

Jul 15th, 2019 - The purpose of this clinical practice update is to define key principles in the surveillance of hepatobiliary cancers including cholangiocarcinoma, gallbladder adenocarcinoma, and hepatocellular carcinoma in patients with primary sclerosing cholan...

Jun 3rd, 2019 - These guidelines on the management of primary sclerosing cholangitis (PSC) were commissioned by the British Society of Gastroenterology liver section. The guideline writing committee included medical representatives from hepatology and gastroenter...

May 5th, 2019 - Biliary obstruction is a serious condition that can occur in the setting of both benign and malignant pathologies. In the setting of acute cholangitis, biliary decompression can be lifesaving; for patients with cancer who are receiving chemotherap...

Apr 13th, 2019 - Each year choledocholithiasis results in biliary obstruction, cholangitis, and pancreatitis in a significant number of patients. The primary treatment, ERCP, is minimally invasive but associated with adverse events in 6% to 15%. This American Soci...

Dec 23rd, 2018 - IgG4-related sclerosing cholangitis (IgG4-SC) is a distinct type of cholangitis frequently associated with autoimmune pancreatitis and currently recognized as a biliary manifestation of IgG4-related disease. Although clinical diagnostic criteria o...

Jan 19th, 2021 - Liver chemistry abnormalities are a frequent manifestation of coronavirus disease 2019 (COVID-19) but are usually transient and resolve with disease resolution. We describe the clinical course and histologic features of 3 adults who developed prol...

Jan 19th, 2021 - The optimal antibiotic therapy duration for cholangitis is unclear. Guideline recommendations vary between 4 and 14 days after biliary drainage. Clinical observations and some evidence however suggest that shorter antibiotic therapy may be suffici...

Jan 19th, 2021 - Primary biliary cholangitis (PBC) is a prototypical organ specific autoimmune disease, mediated by autoreactive T cell attack and destruction of cholangiocytes. Despite the clear role of autoimmunity in PBC, immune-directed therapies have failed t...

Jan 19th, 2021 - Recurrent primary biliary cholangitis (rPBC) occurs in up to 53% of LT recipients transplanted for PBC and negatively impacts long term graft (Hazard ratio 2.01) and patient survival (hazard ratio 1.72)(1). In multiple cohort studies, use of ursod...

Jan 18th, 2021 - Amidst the coronavirus (COVID-19) pandemic, the American Society for Transplant Surgeons has recommended that only urgent liver transplant with deceased donors should occur. However, young pediatric candidates rely on living donors for lifesaving ...

Jan 11th, 2021 - NEW YORK (Reuters Health) - The gut microbiomes of patients with primary sclerosing cholangitis (PSC) show major functional differences from those of healthy controls (HCs), new findings show. Individuals with PSC had fewer genes involved in synth...

Nov 13th, 2020 - Patients with primary biliary cholangitis experienced rapid improvements in itch and quality of life after treatment with linerixibat in a randomized placebo-controlled trial of the safety, efficacy, and tolerability of the small-molecule drug. Mo...

Nov 13th, 2020 - Patients with primary biliary cholangitis experienced rapid improvements in itch and quality of life after treatment with linerixibat in a randomized placebo-controlled trial of the safety, efficacy, and tolerability of the small-molecule drug. Mo...

Nov 4th, 2020 - (Reuters Health) - Patients with moderate to severe primary or secondary sclerosing cholangitis experienced greater reduction of pruritis with bezafibrate than with placebo, a small trial found. Researchers examined data on 44 patients with primar...

Nov 4th, 2020 - (Reuters Health) - Patients with moderate to severe primary or secondary sclerosing cholangitis experienced greater reduction of pruritis with bezafibrate than with placebo, a small trial found. Researchers examined data on 44 patients with primar...