ALLMedicine™ Colon Cancer Center

Dec 2nd, 2020 - Although it is known that oncolytic viruses can inflame and recruit immune cells to otherwise immunosuppressed tumor microenvironments, the influence of the antiviral immune response on antitumor immunity is less clear across viral platforms and t...

Dec 2nd, 2020 - Cohesin plays an essential role in chromatin loop extrusion, but its impact on a compartmentalized nuclear architecture, linked to nuclear functions, is less well understood. Using live-cell and super-resolved 3D microscopy, here we find that cohe...

Dec 2nd, 2020 - Hydroxylated chalcones are phytochemicals which are biosynthetic precursors of flavonoids and their 1,3-diaryl-prop-2-en-1-one structure is used as a scaffold for drug development. In this study, the structure-dependent activation of aryl hydrocar...

Dec 2nd, 2020 - Japanese authors first reported a reversible cardiomyopathy due to emotional stress known as Takotsubo cardiomyopathy or stress-induced cardiomyopathy or apical ballooning syndrome. In this case report, we describe Takotsubo cardiomyopathy associa...

Dec 1st, 2020 - Pericentromeric human satellite II (HSATII) repeats are normally silent but can be actively transcribed in tumor cells, where increased HSATII copy number is associated with a poor prognosis in colon cancer, and in human cytomegalovirus (HCMV)-inf...

Jul 23rd, 2020 - Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.|2020|Argilés G,Tabernero J,Labianca R,Hochhauser D,Salazar R,|

May 31st, 2020 - Alberto F. Sobrero, MD, of the Ospedale San Martino, discusses final results of the IDEA study, which supported the use of 3 months of adjuvant CAPOX, vs 6 months, for most patients with stage III colon cancer. The shorter treatment duration reduc...

May 29th, 2020 - Jeffrey A. Meyerhardt, MD, MPH, of Dana-Farber Cancer Institute, discusses results from the CALGB/SWOG 80702 trial of celecoxib plus standard adjuvant therapy with fluorouracil, leucovorin, and oxaliplatin (FOLFOX). Adding celecoxib to standard ch...

May 28th, 2020 - Prospective evaluation of nearly 13,000 individuals with stage III colon cancer found minimal difference in 5-year overall survival (OS) with 3 versus 6 months of adjuvant CAPOX or FOLFOX for the majority of patients, according to the final result...

May 28th, 2020 - Patients with untreated heavily mutated metastatic colorectal cancer (mCRC) lived twice as long without disease progression when they received an immune checkpoint inhibitor instead of chemotherapy, a randomized trial showed.

Dec 2nd, 2020 - Although it is known that oncolytic viruses can inflame and recruit immune cells to otherwise immunosuppressed tumor microenvironments, the influence of the antiviral immune response on antitumor immunity is less clear across viral platforms and t...

Dec 2nd, 2020 - Cohesin plays an essential role in chromatin loop extrusion, but its impact on a compartmentalized nuclear architecture, linked to nuclear functions, is less well understood. Using live-cell and super-resolved 3D microscopy, here we find that cohe...

Dec 2nd, 2020 - Hydroxylated chalcones are phytochemicals which are biosynthetic precursors of flavonoids and their 1,3-diaryl-prop-2-en-1-one structure is used as a scaffold for drug development. In this study, the structure-dependent activation of aryl hydrocar...

Dec 2nd, 2020 - Japanese authors first reported a reversible cardiomyopathy due to emotional stress known as Takotsubo cardiomyopathy or stress-induced cardiomyopathy or apical ballooning syndrome. In this case report, we describe Takotsubo cardiomyopathy associa...

Dec 1st, 2020 - Pericentromeric human satellite II (HSATII) repeats are normally silent but can be actively transcribed in tumor cells, where increased HSATII copy number is associated with a poor prognosis in colon cancer, and in human cytomegalovirus (HCMV)-inf...

Nov 8th, 2020 - NEW YORK (Reuters Health) - The technical skills of the surgeon have a considerable impact on patient outcomes followings colon-cancer surgery, according to a new study. "It may seem obvious but it's the first time ever demonstrated - surgeon tech...

Nov 2nd, 2020 - (Reuters Health) - Older adults with vision impairment are less likely to receive recommended breast and colon cancer screenings than peers without vision problems, a U.S. study suggests. Researchers examined data from the 2015 and 2018 National H...

Nov 2nd, 2020 - The guideline on localized colon cancer was released on October 1, 2020 by the European Society for Medical Oncology.[1] Invasive Screening   A complete colonoscopy is the recommended method for colorectal cancer (CRC) screening in average-risk me...

Nov 2nd, 2020 - The guideline on localized colon cancer was released on October 1, 2020 by the European Society for Medical Oncology.[1] Invasive Screening   A complete colonoscopy is the recommended method for colorectal cancer (CRC) screening in average-risk me...

Nov 2nd, 2020 - (Reuters Health) - Older adults with vision impairment are less likely to receive recommended breast and colon cancer screenings than peers without vision problems, a U.S. study suggests. Researchers examined data from the 2015 and 2018 National H...