ALLMedicine™ Colon Cancer Center

Aug 1st, 2021 - Embryonal rhabdomyosarcoma (eRMS) is the most common type of rhabdomyosarcoma in children. eRMS is characterized by malignant skeletal muscle cells driven by hyperactivation of several oncogenic pathways including the MYC pathway. Targeting MYC in...

Jul 31st, 2021 - Natural cyclopeptide RA-XII, isolated from Rubia yunnanensis, is a promising chemotherapeutic agent for colon cancer. The photosensitizer protoporphyrin-IX attached with triphenylphosphonium (TPP) could possess mitochondria targeting capacity and ...

Jul 31st, 2021 - Hereditary colorectal cancer syndromes attributable to high penetrance mutations represent 9-26% of young-onset colorectal cancer cases. The clinical significance of many of these mutations is understood well enough to be used in diagnostics and a...

Jul 29th, 2021 - Autophagy, a process of self-digestion, is closely related to multiple biological processes of colon cancer. This study aimed to construct and evaluate prognostic signature of autophagy-related genes (ARGs) to predict overall survival (OS) in colo...

Jul 29th, 2021 - Uncertainty exists about a possible survival benefit of primary tumor resection (PTR) in synchronous metastatic colon cancer (mCC). Since sidedness of the primary tumor is regarded as an important prognostic factor, our objective was to study the ...

Jul 24th, 2020 - Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.|2020|Argilés G,Tabernero J,Labianca R,Hochhauser D,Salazar R,|diagnosis,epidemiology,therapy,

Apr 16th, 2019 - To develop recommendations for duration of adjuvant chemotherapy with a fluoropyrimidine and oxaliplatin for patients with completely resected stage III colon cancer based on the results of trials of 3 months compared with 6 months of treatment. A...

Aug 17th, 2018 - The annual Eastern Canadian Gastrointestinal Cancer Consensus Conference 2017 was held in St. John's, Newfoundland and Labrador, 28-30 September. Experts in radiation oncology, medical oncology, surgical oncology, and cancer genetics who are invol...

Jan 1st, 2018 - Improved therapy has substantially increased survival of persons with cystic fibrosis (CF). But the risk of colorectal cancer (CRC) in adults with CF is 5-10 times greater compared to the general population, and 25-30 times greater in CF patients ...

Aug 24th, 2017 - Ovarian cancer is the second most common type of female reproductive cancer, and more women die from ovarian cancer than from cervical cancer and uterine cancer combined. Currently, there is no strategy for early detection of ovarian cancer that r...

May 7th, 2020 - We have previously reported that TP53 (encoding p53 protein), one of the most frequently mutated genes in human cancers, dose dependently modulates the balance between the utilization of oxidative and glycolytic pathways for energy generation in h...

May 1st, 2020 - While safety and feasibility as well as some improvements in fitness, fatigue and certain aspects of quality of life have been shown for physical activity in cancer patients during treatment, none of the pre-requisites above (i-iv) is fulfilled in...

Apr 28th, 2020 - QoLiCOL is an explorative, prospective, longitudinal, non-interventional, international, multicenter study of health-related quality of life, physical symptoms, functional impairments and socioeconomic burden in colon cancer patients. All patients...

Apr 17th, 2020 - Colorectal cancer is the third most common malignancy for both women and men and is responsible for almost 10% of all cancer death. Despite complete removal of the tumor and use of adjuvant chemotherapy, up to 25% of patients with stage II colon c...

Apr 6th, 2020 - In recent randomized studies with preoperative combined chemotherapy and external beam radiation (EBRT/CT) with total mesorectal excision (TME surgery), the compliance to adjuvant chemotherapy ranged from 42.9% to 70%. This low compliance rate cou...

Jul 20th, 2021 - NEW YORK (Reuters Health) - An antibody-based multitarget fecal immunochemical test (mtFIT) for colorectal cancer (CRC) screening is more accurate in detecting advanced neoplasia compared with the standard FIT test, without compromising specificit...

Jul 16th, 2021 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook. A study sugge...

Jul 8th, 2021 - Albuquerque oncologist Barbara McAneny, MD, has a patient in his 30s who experienced rectal bleeding for 6 months last year but didn't see a physician because he was afraid of catching COVID-19. He hoped it was just hemorrhoids. When he finally ca...

Jul 5th, 2021 - Exposure to antibiotics appears to be associated with the development of colon cancer, particularly in younger people, and could be contributing to the increase in early onset colorectal cancer (CRC) that is being documented, say UK researchers. T...

Jun 22nd, 2021 - NEW YORK (Reuters Health) - Red meat consumption has been consistently linked to an increased risk for colorectal cancer and a new study provides a mechanistic reason. "Our study identified for the first time an alkylating mutational signature in ...