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About 49,016 results

ALLMedicine™ Colon Cancer Center

Research & Reviews  22,651 results

Recombinant Orthopoxvirus Primes Colon Cancer for Checkpoint Inhibitor and Cross-Primes...
https://doi.org/10.1158/1535-7163.MCT-20-0405
Molecular Cancer Therapeutics; Kim SI, Park AK et. al.

Dec 2nd, 2020 - Although it is known that oncolytic viruses can inflame and recruit immune cells to otherwise immunosuppressed tumor microenvironments, the influence of the antiviral immune response on antitumor immunity is less clear across viral platforms and t...

Cohesin depleted cells rebuild functional nuclear compartments after endomitosis.
https://doi.org/10.1038/s41467-020-19876-6
Nature Communications; Cremer M, Brandstetter K et. al.

Dec 2nd, 2020 - Cohesin plays an essential role in chromatin loop extrusion, but its impact on a compartmentalized nuclear architecture, linked to nuclear functions, is less well understood. Using live-cell and super-resolved 3D microscopy, here we find that cohe...

Hydroxylated Chalcones as Aryl Hydrocarbon Receptor Agonists: Structure-Activity Effects.
https://doi.org/10.1093/toxsci/kfaa179
Toxicological Sciences : an Official Journal of the Society of Toxicology; Park H, Jin UH et. al.

Dec 2nd, 2020 - Hydroxylated chalcones are phytochemicals which are biosynthetic precursors of flavonoids and their 1,3-diaryl-prop-2-en-1-one structure is used as a scaffold for drug development. In this study, the structure-dependent activation of aryl hydrocar...

Takotsubo Cardiomyopathy and LV Outflow Tract Obstruction after Initiation of Novel Ora...
https://www.ncbi.nlm.nih.gov/pubmed/33261234
Rhode Island Medical Journal (2013); Arunachalam K, Gnanaguruparan S et. al.

Dec 2nd, 2020 - Japanese authors first reported a reversible cardiomyopathy due to emotional stress known as Takotsubo cardiomyopathy or stress-induced cardiomyopathy or apical ballooning syndrome. In this case report, we describe Takotsubo cardiomyopathy associa...

HSATII RNA is induced via a noncanonical ATM-regulated DNA damage response pathway and ...
https://doi.org/10.1073/pnas.2017734117 10.3324/haematol.2019.234385
Proceedings of the National Academy of Sciences of the United States of America; Nogalski MT, Shenk T

Dec 1st, 2020 - Pericentromeric human satellite II (HSATII) repeats are normally silent but can be actively transcribed in tumor cells, where increased HSATII copy number is associated with a poor prognosis in colon cancer, and in human cytomegalovirus (HCMV)-inf...

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Guidelines  79 results

Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and ...
https://doi.org/10.1016/j.annonc.2020.06.022
Annals of Oncology : Official Journal of the European Society for Medical Oncology; Argilés G, Tabernero J et. al.

Jul 23rd, 2020 - Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.|2020|Argilés G,Tabernero J,Labianca R,Hochhauser D,Salazar R,|

Alberto F. Sobrero, MD, on Colon Cancer: Adjuvant Oxaliplatin and Fluoropyrimidine-Based Therapy for Stage III Disease
https://ascopost.com/videos/asco20-virtual-scientific-program/alberto-sobrero-on-adjuvant-oxaliplatin-and-fluoropyrimidine-based-therapy-for-stage-iii-colon-cancer/

May 31st, 2020 - Alberto F. Sobrero, MD, of the Ospedale San Martino, discusses final results of the IDEA study, which supported the use of 3 months of adjuvant CAPOX, vs 6 months, for most patients with stage III colon cancer. The shorter treatment duration reduc...

Jeffrey A. Meyerhardt, MD, MPH, on Colon Cancer: Celecoxib and FOLFOX for Stage III Disease
https://ascopost.com/videos/asco20-virtual-scientific-program/jeffrey-meyerhardt-on-celecoxib-and-folfox-for-stage-iii-colon-cancer/

May 29th, 2020 - Jeffrey A. Meyerhardt, MD, MPH, of Dana-Farber Cancer Institute, discusses results from the CALGB/SWOG 80702 trial of celecoxib plus standard adjuvant therapy with fluorouracil, leucovorin, and oxaliplatin (FOLFOX). Adding celecoxib to standard ch...

Final IDEA Collaboration Results Support Just 3 Months of Adjuvant CAPOX for Most Patients With Stage III Colon Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200177/full/

May 28th, 2020 - Prospective evaluation of nearly 13,000 individuals with stage III colon cancer found minimal difference in 5-year overall survival (OS) with 3 versus 6 months of adjuvant CAPOX or FOLFOX for the majority of patients, according to the final result...

First-Line Win for Anti-PD-1 Drug in Advanced Colon Cancer
https://www.medpagetoday.com/meetingcoverage/asco/86763

May 28th, 2020 - Patients with untreated heavily mutated metastatic colorectal cancer (mCRC) lived twice as long without disease progression when they received an immune checkpoint inhibitor instead of chemotherapy, a randomized trial showed.

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Drugs  129 results see all →

Clinicaltrials.gov  24,501 results

Recombinant Orthopoxvirus Primes Colon Cancer for Checkpoint Inhibitor and Cross-Primes...
https://doi.org/10.1158/1535-7163.MCT-20-0405
Molecular Cancer Therapeutics; Kim SI, Park AK et. al.

Dec 2nd, 2020 - Although it is known that oncolytic viruses can inflame and recruit immune cells to otherwise immunosuppressed tumor microenvironments, the influence of the antiviral immune response on antitumor immunity is less clear across viral platforms and t...

Cohesin depleted cells rebuild functional nuclear compartments after endomitosis.
https://doi.org/10.1038/s41467-020-19876-6
Nature Communications; Cremer M, Brandstetter K et. al.

Dec 2nd, 2020 - Cohesin plays an essential role in chromatin loop extrusion, but its impact on a compartmentalized nuclear architecture, linked to nuclear functions, is less well understood. Using live-cell and super-resolved 3D microscopy, here we find that cohe...

Hydroxylated Chalcones as Aryl Hydrocarbon Receptor Agonists: Structure-Activity Effects.
https://doi.org/10.1093/toxsci/kfaa179
Toxicological Sciences : an Official Journal of the Society of Toxicology; Park H, Jin UH et. al.

Dec 2nd, 2020 - Hydroxylated chalcones are phytochemicals which are biosynthetic precursors of flavonoids and their 1,3-diaryl-prop-2-en-1-one structure is used as a scaffold for drug development. In this study, the structure-dependent activation of aryl hydrocar...

Takotsubo Cardiomyopathy and LV Outflow Tract Obstruction after Initiation of Novel Ora...
https://www.ncbi.nlm.nih.gov/pubmed/33261234
Rhode Island Medical Journal (2013); Arunachalam K, Gnanaguruparan S et. al.

Dec 2nd, 2020 - Japanese authors first reported a reversible cardiomyopathy due to emotional stress known as Takotsubo cardiomyopathy or stress-induced cardiomyopathy or apical ballooning syndrome. In this case report, we describe Takotsubo cardiomyopathy associa...

HSATII RNA is induced via a noncanonical ATM-regulated DNA damage response pathway and ...
https://doi.org/10.1073/pnas.2017734117 10.3324/haematol.2019.234385
Proceedings of the National Academy of Sciences of the United States of America; Nogalski MT, Shenk T

Dec 1st, 2020 - Pericentromeric human satellite II (HSATII) repeats are normally silent but can be actively transcribed in tumor cells, where increased HSATII copy number is associated with a poor prognosis in colon cancer, and in human cytomegalovirus (HCMV)-inf...

see more →

News  1,557 results

Surgeon Technical Skill Has Big Impact on Colon Cancer Outcomes
https://www.medscape.com/viewarticle/940538

Nov 8th, 2020 - NEW YORK (Reuters Health) - The technical skills of the surgeon have a considerable impact on patient outcomes followings colon-cancer surgery, according to a new study. "It may seem obvious but it's the first time ever demonstrated - surgeon tech...

Vision Impairment Tied to Less Use of Cancer Screenings by Older Adults
https://www.staging.medscape.com/viewarticle/940183

Nov 2nd, 2020 - (Reuters Health) - Older adults with vision impairment are less likely to receive recommended breast and colon cancer screenings than peers without vision problems, a U.S. study suggests. Researchers examined data from the 2015 and 2018 National H...

Localized Colon Cancer Clinical Practice Guidelines (ESMO, 2020)
https://reference.staging.medscape.com/viewarticle/940055

Nov 2nd, 2020 - The guideline on localized colon cancer was released on October 1, 2020 by the European Society for Medical Oncology.[1] Invasive Screening   A complete colonoscopy is the recommended method for colorectal cancer (CRC) screening in average-risk me...

Localized Colon Cancer Clinical Practice Guidelines (ESMO, 2020)
https://reference.medscape.com/viewarticle/940055

Nov 2nd, 2020 - The guideline on localized colon cancer was released on October 1, 2020 by the European Society for Medical Oncology.[1] Invasive Screening   A complete colonoscopy is the recommended method for colorectal cancer (CRC) screening in average-risk me...

Vision Impairment Tied to Less Use of Cancer Screenings by Older Adults
https://www.medscape.com/viewarticle/940183

Nov 2nd, 2020 - (Reuters Health) - Older adults with vision impairment are less likely to receive recommended breast and colon cancer screenings than peers without vision problems, a U.S. study suggests. Researchers examined data from the 2015 and 2018 National H...

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Patient Education  99 results see all →