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About 2,234 results

ALLMedicine™ Hirschsprung Disease Center

Research & Reviews  1,115 results

What is the appropriate aganglionic bowel length on contrast enema for attempting singl...
https://doi.org/10.1016/j.jpedsurg.2020.08.018
Journal of Pediatric Surgery; Ashjaei B, Ghamari Khameneh A et. al.

Sep 18th, 2020 - To identify influence of different values of age and abnormal bowel length in HD patients selected for single stage TERPT which affects the technique of surgery. This observational study was carried out for over 2.5 years. All children younger tha...

Male-biased aganglionic megacolon in the TashT mouse model of Hirschsprung disease invo...
https://doi.org/10.1371/journal.pgen.1009008
PLoS Genetics; Cardinal T, Bergeron KF et. al.

Sep 8th, 2020 - Hirschsprung disease (HSCR) is a complex genetic disorder of neural crest development resulting in incomplete formation of the enteric nervous system (ENS). This life-threatening neurocristopathy affects 1/5000 live births, with a currently unexpl...

Intestinal proinflammatory macrophages induce a phenotypic switch in interstitial cells...
https://doi.org/10.1172/JCI126584
The Journal of Clinical Investigation; Chen X, Meng X et. al.

Aug 18th, 2020 - Interstitial cells of Cajal (ICCs) are pacemaker cells in the intestine, and their function can be compromised due to loss of C-KIT expression. Macrophage activation has been identified in intestine affected by Hirschsprung disease associated ente...

Minimally Invasive Redo Pull-Throughs in Hirschsprung Disease.
https://doi.org/10.1089/lap.2020.0250
Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A; Pini Prato A, Arnoldi R et. al.

Jul 27th, 2020 - Introduction: To reoperate a patient with Hirschsprung disease (HSCR) can be technically demanding and most surgeons would resort to conventional laparotomy. This article describes a series of patients with postoperative obstructive symptoms who u...

Glial Cell Derived Neurotrophic Factor Induces Enteric Neurogenesis and Improves Colon ...
https://doi.org/10.1053/j.gastro.2020.07.018
Gastroenterology Soret R, Schneider S et. al.

Jul 20th, 2020 - Hirschsprung disease (HSCR) is a life-threatening birth defect in which the distal colon is devoid of enteric neural ganglia. HSCR is treated by surgical removal of aganglionic bowel, but many children continue to have severe problems after surger...

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Clinicaltrials.gov  1,117 results

What is the appropriate aganglionic bowel length on contrast enema for attempting singl...
https://doi.org/10.1016/j.jpedsurg.2020.08.018
Journal of Pediatric Surgery; Ashjaei B, Ghamari Khameneh A et. al.

Sep 18th, 2020 - To identify influence of different values of age and abnormal bowel length in HD patients selected for single stage TERPT which affects the technique of surgery. This observational study was carried out for over 2.5 years. All children younger tha...

Male-biased aganglionic megacolon in the TashT mouse model of Hirschsprung disease invo...
https://doi.org/10.1371/journal.pgen.1009008
PLoS Genetics; Cardinal T, Bergeron KF et. al.

Sep 8th, 2020 - Hirschsprung disease (HSCR) is a complex genetic disorder of neural crest development resulting in incomplete formation of the enteric nervous system (ENS). This life-threatening neurocristopathy affects 1/5000 live births, with a currently unexpl...

Intestinal proinflammatory macrophages induce a phenotypic switch in interstitial cells...
https://doi.org/10.1172/JCI126584
The Journal of Clinical Investigation; Chen X, Meng X et. al.

Aug 18th, 2020 - Interstitial cells of Cajal (ICCs) are pacemaker cells in the intestine, and their function can be compromised due to loss of C-KIT expression. Macrophage activation has been identified in intestine affected by Hirschsprung disease associated ente...

Minimally Invasive Redo Pull-Throughs in Hirschsprung Disease.
https://doi.org/10.1089/lap.2020.0250
Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A; Pini Prato A, Arnoldi R et. al.

Jul 27th, 2020 - Introduction: To reoperate a patient with Hirschsprung disease (HSCR) can be technically demanding and most surgeons would resort to conventional laparotomy. This article describes a series of patients with postoperative obstructive symptoms who u...

Glial Cell Derived Neurotrophic Factor Induces Enteric Neurogenesis and Improves Colon ...
https://doi.org/10.1053/j.gastro.2020.07.018
Gastroenterology Soret R, Schneider S et. al.

Jul 20th, 2020 - Hirschsprung disease (HSCR) is a life-threatening birth defect in which the distal colon is devoid of enteric neural ganglia. HSCR is treated by surgical removal of aganglionic bowel, but many children continue to have severe problems after surger...

see more →

News  1 results

Study lays groundwork for autologous nerve cell transplantation in Hirschsprung disease
https://www.mdedge.com/familymedicine/article/104775/gastroenterology/study-lays-groundwork-autologous-nerve-cell
GI and Hepatology News; Amy Karon

Jan 1st, 2016 - Neural progenitor cells from the proximal colons of patients with Hirschsprung disease divided and formed neurons and glia in their own distal aganglionic colon tissue, according to a study published in the January issue of Cellular and Molecular.

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Patient Education  1 results see all →