About 37,765 results

ALLMedicine™ Constipation Center

Research & Reviews  7,877 results

A Review of the Cardiovascular Safety of Prucalopride in Patients with Chronic Idiopath...
The American Journal of Gastroenterology; Tack J, Derakhchan K et. al.

Mar 18th, 2023 - Prokinetic agents, specifically 5-hydroxytryptamine type 4 (5-HT4) receptor agonists, have been shown to provide relief in chronic idiopathic constipation (CIC). The first 5-HT4 agonists were initially withdrawn from use owing to associations with...

Functional constipation in children: What physicians should know.
World Journal of Gastroenterology; Tran DL, Sintusek P

Mar 18th, 2023 - Functional constipation (FC) is considered the most common functional gastrointestinal disorder in children with a pooled global prevalence of 14.4% (95% confidence interval: 11.2-17.6) when diagnosed based on the Rome IV criteria. Its pathophysio...

Abdominal Hernias Workup

Mar 16th, 2023 - Approach Considerations Laboratory studies are not specific for hernia but may be useful for general medical evaluation. Imaging studies are not required in the normal workup of a hernia [7, 8] ; however, radiography, computed tomography (CT), or ...

Fanconi Syndrome Clinical Presentation

Mar 16th, 2023 - History The clinical features that cause patients to seek medical care include polyuria, polydipsia, bouts of dehydration (sometimes associated with fever), bone deformities, and impaired growth. Less often, the reasons for investigation are labor...

Nicotinamide Riboside Improves Enteric Neuropathy in Streptozocin-Induced Diabetic Rats...
Digestive Diseases and Sciences; Costa CJ, Cohen MW et. al.

Mar 16th, 2023 - Diabetes Mellitus causes a systemic oxidative stress due in part to the hyperglycemia and the reactive oxygen species generated. Up to 75% of diabetic patients present with an autonomic neuropathy affecting the Enteric Nervous System. Deficits in ...

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Guidelines  18 results

Age and Ageing; Wong E, Payab Q et. al.

Jan 16th, 2023 - Constipation is a common diagnosis among hospitalized patients. It results in considerable morbidity in elderly patients, healthcare utilization and economic burden. Laxatives are commonly prescribed but poorly monitored due to benign side effect ...

AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Sy...
Gastroenterology Chang L, Sultan S et. al.

Jun 24th, 2022 - Irritable bowel syndrome (IBS) is a common disorder of gut-brain interaction associated with significant disease burden. This American Gastroenterological Association guideline is intended to support practitioners in decisions about the use of med...

My Treatment Approach to Multiple System Atrophy.
Mayo Clinic Proceedings; Coon EA, Ahlskog JE

Mar 7th, 2021 - Multiple system atrophy (MSA) is a neurodegenerative disorder primarily characterized by autonomic failure plus parkinsonism or cerebellar ataxia. The diagnosis may be challenging and is usually made at a tertiary care center. The long-term manage...

European society of neurogastroenterology and motility guidelines on functional constip...
Neurogastroenterology and Motility : the Official Journal... Serra J, Pohl D et. al.

Nov 23rd, 2019 - Chronic constipation is a common disorder with a reported prevalence ranging from 3% to 27% in the general population. Several management strategies, including diagnostic tests, empiric treatments, and specific treatments, have been developed. Our...

Medical Management of Opioid-Induced Constipation.
JAMA Rao VL, Micic D et. al.

Nov 5th, 2019 - Medical Management of Opioid-Induced Constipation.|2019|Rao VL,Micic D,Davis AM,|adverse effects,therapeutic use,therapeutic use,therapeutic use,analogs & derivatives,therapeutic use,therapeutic use,drug therapy,therapeutic use,

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Drugs  2,979 results see all →

Clinicaltrials.gov  1,540 results

Obeticholic Acid in Bile Acid Diarrhoea

Mar 10th, 2023 - Bile acid diarrhoea (BAD) is an under-recognised but common condition of chronic watery diarrhoea. BAD may be secondary to ileal disease affecting the reabsorption and the enterohepatic circulation of bile acids (bile acid malabsorption) or can be...

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

Mar 9th, 2023 - INCB7839 is an inhibitor of the ADAM (A Disintegrin and Metalloprotease) 10 and 17 proteases. Neuronal activity regulates glioma growth through neuroligin-3 (NLGN3). ADAM 10 is the protease responsible for NLGN3 release into the tumor microenviron...

The Effect of Progressive Muscle Relaxation Exercise on Sleep Quality

Mar 9th, 2023 - Chemotherapy is defined as treatment with chemical drugs that prevent the proliferation of malignant tumor cells, kill the cell or stop its function. Since these chemical agents affect healthy cells as well as diseased cells, they can cause seriou...

Domperidone Expanded Access Protocol for Patients With Gastrointestinal Disorders

Mar 9th, 2023 - Expanded Access Program Design: The purpose of the Expanded Access Program is to provide oral Domperidone to patients' ≥12 years of age where, according to the investigator's judgment, a prokinetic effect is needed for the relief of refractory gas...

Investigating the Equivalence of the EORTC QLQ-C30 and the QLQ-F17

Mar 9th, 2023 - The EORTC QLQ-C30, a patient-reported outcome measure (PROM) that is available in 110 different languages, has been used in thousands of clinical cancer trials worldwide. The QLQ-C30 is composed of six functioning scales (including a measure for g...

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News  2,199 results

More on ‘intellectual constipation’ and more
Robert W. Pollack, MD, ABPN, DLFAPA, Paul R. Crosby, MD, MBA et. al.

Feb 24th, 2023 - More on ‘intellectual constipation’ Regarding your editorial, “From debate to stalemate and hate: An epidemic of intellectual constipation” (Current Psychiatry, January 2023, p. 3-4, doi:10.

Targeted Agents Go Head-to-Head for Newly Diagnosed Ph+ ALL

Feb 16th, 2023 - In the first randomized comparison of targeted agents for acute lymphoblastic leukemia (ALL), ponatinib (Iclusig) prevailed over imatinib for untreated Philadelphia chromosome-positive (Ph+) cases. More than twice as many patients treated with pon...

Oral Drug Shows Benefit for Notalgia Paresthetica in Mid-Stage Trial

Feb 8th, 2023 - A selective kappa opioid receptor agonist in patients with notalgia paresthetica led to "modestly" greater improvements in itchiness over placebo, but was associated with adverse events, a randomized phase II trial showed. At 8 weeks, improvements...

One Diet Appeared Tops for Short-Term Seizure Control in Pediatric Epilepsy

Jan 31st, 2023 - In children with drug-resistant epilepsy, the modified Atkins and ketogenic diets were more effective than usual care in achieving large short-term reductions in seizures and short-term seizure freedom, a systematic review and network meta-analysi...

Acute hepatic porphyrias no longer as rare as previously thought
Carolyn Crist

Jan 30th, 2023 - Although rare, acute hepatic porphyrias (AHPs) may be more common than previously thought, particularly among women between ages 15 and 50, according to a new clinical practice update from the American Gastroenterological Association. For acute at.

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Patient Education  493 results see all →