ALLMedicine™ Hereditary Colorectal Cancer Center

May 17th, 2022 - Around 10% to 16% of colorectal cancer patients have a pathogenic variant in a cancer susceptibility gene. Some of these variants are in cancer genes that are associated with colorectal cancer while others are not. The hereditary colorectal cancer...

Apr 26th, 2022 - Hereditary colorectal cancer syndromes require timely endoscopic surveillance. This study evaluated the approach of Italian gastroenterologists to the management of such patients. It then assessed the impact of SARS-CoV-2. All members affiliated w...

Mar 31st, 2022 - Approximately 5% of all colorectal cancers develop within a hereditary colorectal cancer syndrome. Patients and families with these syndromes have an increased risk of colorectal and extracolonic cancers that develop at an early age. Recognition a...

Mar 29th, 2022 - This study aimed to establish a practical protocol for early noninvasive prenatal testing (NIPT) for fetuses at risk of Peutz-Jeghers syndrome or familial adenomatous polyposis, two classical types of hereditary colorectal cancer syndromes, for ri...

Mar 26th, 2022 - Diagnosis of Lynch and other hereditary colorectal cancer (CRC) syndromes through germline genetic testing has important implications for treatment and risk-management, yet guideline-recommended genetic counseling referral and attendance is subopt...

Nov 30th, 2019 - Heritable factors account for approximately 35% of colorectal cancer (CRC) risk, and almost 30% of the population in the UK have a family history of CRC. The quantification of an individual's lifetime risk of gastrointestinal cancer may incorporat...

Aug 9th, 2016 - This is a focused update highlighting the most current NCCN Guidelines for diagnosis and management of Lynch syndrome. Lynch syndrome is the most common cause of hereditary colorectal cancer, usually resulting from a germline mutation in 1 of 4 DN...

Dec 3rd, 2014 - To provide recommendations on prevention, screening, genetics, treatment, and management for people at risk for hereditary colorectal cancer (CRC) syndromes. The American Society of Clinical Oncology (ASCO) has a policy and set of procedures for e...

Feb 21st, 2020 - In this study, gene mutation profiling was performed on primary tissue samples from colorectal cancer patients who met relevant clinical screening criteria, unearthing suspected germline pathogenic mutations. At the same time, germline mutation de...

Apr 2nd, 2021 - Today- FDA approvals of a biosimilar and a direct-to-consumer genetic test, a breakthrough designation in marginal zone lymphoma, a complete response letter in triple-negative breast cancer, and supplemental biologics license application in mul...

Dec 4th, 2020 - John Burn, MD Long-term aspirin use significantly lowered the risk of developing colorectal cancer (CRC) in Lynch syndrome carriers while ameliorating the added risk associated with obesity, according to a new analysis from the CAPP2 trial publis...

Feb 1st, 2020 - Dear colleagues, The first issue of The New Gastroenterologist in 2020 consists of a particularly interesting array of articles and the introduction of a new medical ethics series! Dr. Vijaya Rao This month’s “In Focus” article, brought to you by.

Jun 6th, 2019 - Henry T. Lynch, MD, PhD, world-renowned pioneer in the study of hereditary cancers, who discovered the most common form of hereditary colorectal cancer, known as Lynch syndrome, died on June 2 at the age of 91. Dr Henry Lynch "Dr Lynch has captain...

Jun 6th, 2019 - Henry T. Lynch, MD, PhD, world-renowned pioneer in the study of hereditary cancers, who discovered the most common form of hereditary colorectal cancer, known as Lynch syndrome, died on June 2 at the age of 91. Dr Henry Lynch "Dr Lynch has captain...