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About 543 results

ALLMedicine™ Hereditary Colorectal Cancer Center

Research & Reviews  185 results

Rates and outcomes of testing for lynch syndrome in a national colorectal cancer screen...
https://doi.org/10.1016/j.canep.2022.102314
Cancer Epidemiology; Cudmore J, Kumar L et. al.

Jan 7th, 2023 - Lynch Syndrome (LS), the most common cause of hereditary colorectal cancer (CRC), is characterised by pathogenic variants in mismatch repair (MMR) genes. Universal testing of all CRCs for LS can increase detection. Rates and outcomes of testing in...

Correlation Between Blood Group ,Rh and Obesity With Colorectal Carcinoma
https://clinicaltrials.gov/ct2/show/NCT05520385

Sep 7th, 2022 - Cancer is an important leading cause of great psychosocial and economic burden worldwide and about 1.23 million individual annually affected by CRC which is considered as the most common type of cancer ( 9.7 % of overall cancers )and 8 % ( 608,000...

An approach to germline genetic testing in your practice
https://www.mdedge.com/gihepnews/article/257575/gi-oncology/approach-germline-genetic-testing-your-practice
Carol A. Burke, MD

Sep 4th, 2022 - Traditionally, a hereditary colorectal cancer syndrome (HCCS) was suspected in individuals with an obvious personal and/or family cancer phenotype informed by a three-generation family cancer history. Family history is still required to inform can.

Hereditary Colorectal Cancer Syndromes and Inflammatory Bowel Diseases: an ECCO CONFER ...
https://doi.org/10.1093/ecco-jcc/jjac094
Journal of Crohn's & Colitis; Barberio B, Savarino E et. al.

Jul 1st, 2022 - Hereditary colorectal cancer syndromes [HCCS] are rare polyposis or nonpolyposis syndromes with a higher risk of developing colorectal cancer [CRC]. Coexisting inflammatory bowel disease [IBD], including ulcerative colitis [UC] and Crohn's disease...

Prevalence and risk factors of barrett's esophagus in lynch syndrome.
https://doi.org/10.1007/s10689-022-00298-w
Familial Cancer; Farha N, Lyu R et. al.

Jun 3rd, 2022 - Lynch syndrome (LS), the most common hereditary cause of colorectal cancer, predisposes to upper gastrointestinal neoplasia. The prevalence of Barrett's esophagus (BE) is elevated in some hereditary gastrointestinal cancer syndromes but has not be...

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Guidelines  3 results

Guidelines for the management of hereditary colorectal cancer from the British Society ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034349
Gut Monahan KJ, Bradshaw N et. al.

Nov 30th, 2019 - Heritable factors account for approximately 35% of colorectal cancer (CRC) risk, and almost 30% of the population in the UK have a family history of CRC. The quantification of an individual's lifetime risk of gastrointestinal cancer may incorporat...

Genetic/Familial High-Risk Assessment: Colorectal Version 1.2016, NCCN Clinical Practic...
https://doi.org/10.6004/jnccn.2016.0108
Journal of the National Comprehensive Cancer Network : JN... Provenzale D, Gupta S et. al.

Aug 9th, 2016 - This is a focused update highlighting the most current NCCN Guidelines for diagnosis and management of Lynch syndrome. Lynch syndrome is the most common cause of hereditary colorectal cancer, usually resulting from a germline mutation in 1 of 4 DN...

Hereditary colorectal cancer syndromes: American Society of Clinical Oncology Clinical ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321096
Journal of Clinical Oncology : Official Journal of the Am... Stoffel EM, Mangu PB et. al.

Dec 3rd, 2014 - To provide recommendations on prevention, screening, genetics, treatment, and management for people at risk for hereditary colorectal cancer (CRC) syndromes. The American Society of Clinical Oncology (ASCO) has a policy and set of procedures for e...

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Clinicaltrials.gov  9 results

Correlation Between Blood Group ,Rh and Obesity With Colorectal Carcinoma
https://clinicaltrials.gov/ct2/show/NCT05520385

Sep 7th, 2022 - Cancer is an important leading cause of great psychosocial and economic burden worldwide and about 1.23 million individual annually affected by CRC which is considered as the most common type of cancer ( 9.7 % of overall cancers )and 8 % ( 608,000...

Molecular Basis for Variations in Hereditary Colorectal Cancer Syndromes
https://clinicaltrials.gov/ct2/show/NCT02863172

Jan 24th, 2022 - Participants: Questionnaires: If participant agrees to take part in this study, participant will fill out a some questionnaires about participant's work, family history, medical history, and health habits. If participant has already answered these...

Next-generation Sequencing of Colorectal Cancer Somatic Cells to Guide Genetic Susceptibility Gene Mutations Screening.
https://clinicaltrials.gov/ct2/show/NCT04280666

Feb 21st, 2020 - In this study, gene mutation profiling was performed on primary tissue samples from colorectal cancer patients who met relevant clinical screening criteria, unearthing suspected germline pathogenic mutations. At the same time, germline mutation de...

Molecular Screening for Lynch Syndrome in Denmark
https://clinicaltrials.gov/ct2/show/NCT01845753

Jan 23rd, 2020 - A clinically applicably strategy for molecular screening for Lynch Syndrome is being implemented in Denmark. Based on sequential analysis with immunohistochemistry and methylation analysis, patients with possible hereditary colorectal cancer are i...

Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes
https://clinicaltrials.gov/ct2/show/NCT02198092

Aug 28th, 2019 - This is an observational, case-control study evaluating the quantitative level of Septin9 in plasma pre- and post-colectomy in hereditary colorectal cancer (CRC) syndrome patients (Familial Adenomatous Polyposis (FAP), Lynch syndrome (also known a...

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News  18 results

An approach to germline genetic testing in your practice
https://www.mdedge.com/gihepnews/article/257575/gi-oncology/approach-germline-genetic-testing-your-practice
Carol A. Burke, MD

Sep 4th, 2022 - Traditionally, a hereditary colorectal cancer syndrome (HCCS) was suspected in individuals with an obvious personal and/or family cancer phenotype informed by a three-generation family cancer history. Family history is still required to inform can.

Colorectal Cancer: A Review
https://www.onclive.com/view/colorectal-cancer-a-review

Oct 4th, 2021 - Abstract Colorectal cancer is the third most common type of cancer diagnosed in the United States and is the third most common cause of cancer-related death. The majority of cases are sporadic, with hereditary colon cancer contributing up to 15%...

Pan-cancer Multigene Panel Testing Should Be a Standard Screening Measure in CRC
https://www.onclive.com/view/pan-cancer-multigene-panel-testing-should-be-a-standard-screening-measure-in-crc

May 18th, 2021 - The use of universal tumor screening in conjunction with multigene panel testing led to an improvement in the identification of hereditary cancer syndromes in patients with colorectal cancer (CRC), according to findings from the Ohio Colorectal Ca...

FDA Approvals of a Biosimilar and DTC Genetic Test, Breakthrough Designation in MZL, and More
https://www.onclive.com/view/fda-approvals-of-a-biosimilar-and-dtc-genetic-test-breakthrough-designation-in-mzl-and-more

Apr 2nd, 2021 - Today- FDA approvals of a biosimilar and a direct-to-consumer genetic test, a breakthrough designation in marginal zone lymphoma, a complete response letter in triple-negative breast cancer, and supplemental biologics license application in mul...

Aspirin Reduces CRC Incidence in Individuals at Greatest Risk
https://www.onclive.com/view/aspirin-reduces-crc-incidence-in-individuals-at-greatest-risk

Dec 4th, 2020 - John Burn, MD Long-term aspirin use significantly lowered the risk of developing colorectal cancer (CRC) in Lynch syndrome carriers while ameliorating the added risk associated with obesity, according to a new analysis from the CAPP2 trial publis...

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Patient Education  2 results see all →