ALLMedicine™ Constipation Center

Aug 4th, 2021 - This study aimed to determine the prevalence, symptoms, and associated factors of chronic constipation among older adults in the North-East of Peninsular Malaysia. A cross-sectional study was conducted among older patients from four health clinics...

Aug 3rd, 2021 - Parkinson's disease (PD), the typical neurodegenerative disease, is characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN). However, no therapeutic agent used currently could slow down neuronal cell loss so as t...

Aug 3rd, 2021 - Constipation is a gastrointestinal symptom with high incidence rate and large number of patients. It is becoming one of the urgent medical problems. Poor intestinal motility is one of the important causes of constipation. Current drug treatments f...

Aug 3rd, 2021 - We evaluated factors that can predict the adequacy of bowel preparation in patients with chronic constipation undergoing colonoscopy. We identified patients with chronic constipation who underwent anorectal manometry and at least 1 colonoscopy at ...

Aug 1st, 2021 - Severe kidney dysfunction in a child who presented with constipation: Answers.|2021|Leventoğlu E,Büyükkaragöz B,Fidan K,Gürocak S,|

Mar 7th, 2021 - Multiple system atrophy (MSA) is a neurodegenerative disorder primarily characterized by autonomic failure plus parkinsonism or cerebellar ataxia. The diagnosis may be challenging and is usually made at a tertiary care center. The long-term manage...

Nov 23rd, 2019 - Chronic constipation is a common disorder with a reported prevalence ranging from 3% to 27% in the general population. Several management strategies, including diagnostic tests, empiric treatments, and specific treatments, have been developed. Our...

Nov 5th, 2019 - Medical Management of Opioid-Induced Constipation.|2019|Rao VL,Micic D,Davis AM,|adverse effects,therapeutic use,therapeutic use,therapeutic use,analogs & derivatives,therapeutic use,therapeutic use,drug therapy,therapeutic use,

Aug 10th, 2019 - The Palliative Care Study Group of the Multinational Association for Supportive Care in Cancer formed a subgroup to develop evidence-based recommendations on the management of constipation in patients with advanced cancer. These recommendations we...

Nov 6th, 2018 - Opioid-Induced Constipation (OIC) Guideline.|2018|Crockett S,Greer KB,Sultan S,|adverse effects,chemically induced,diagnosis,drug therapy,physiopathology,drug effects,standards,adverse effects,therapeutic use,adverse effects,therapeutic use,advers...

Apr 24th, 2020 - The objectives of this study are to evaluate the safety, efficacy, and dose response of two delayed release formulations of linaclotide (DR; DR formulation 1 is DR1; DR formulation 2 is DR2) administered orally to patients with irritable bowel syn...

Apr 3rd, 2020 - OBJECTIVES: I. Evaluate the effectiveness of daily oral pilocarpine versus placebo in relieving dry mouth due to the ongoing use of an opioid for cancer related pain at 2 weeks by comparing proportion of patients with at least one response during ...

Mar 25th, 2020 - The aim of the study is to investigate how dietary fibre combinations affects gut physiology, particularly colonic gas production. Comparisons will be made between a single fermentable fibre (inulin), a non-fermentable fibre (psyllium) and a combi...

Mar 25th, 2020 - Defecatory disorders like chronic constipation and faecal incontinence affect 25% of the population with rising incidence. Defecatory disorders pose a major health care burden and are poorly recognized and treated. The need for better diagnostics ...

Feb 28th, 2020 - In preclinical studies Pevonedistat has shown significant single agent activity against mouse xenograft models of AML cell Line HL-60. Also this effect seemed to be synergistically enhanced by combining it with Azacitidine. In clinical arena, Pevo...

Jun 11th, 2021 - NEW YORK (Reuters Health) - When it comes to natural remedies for chronic constipation, kiwifruit, psyllium fiber and prunes all significantly improve constipation symptoms, but kiwifruit has the fewest side effects and is most liked by patients, ...

Jun 2nd, 2021 - Cancer being what it is, I would imagine that all oncologists end up becoming expert managers of pain medications. At our current level of technology, opiates are frequently going to enter that equation, and opiates mean constipation. The result o...

Apr 29th, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update on the use of polyethylene glycol (PEG)-based laxatives together with starch-based thickeners. The MHRA has warned about a potentially harmful interacti...

Apr 27th, 2021 - A call for more appropriate use of a new class of drugs for the treatment of opioid-induced constipation (OIC) has been issued by researchers who found that the number of Medicare beneficiaries who use these drugs, as well as associated costs, soa...

Apr 23rd, 2021 - Atogepant, an oral, small-molecule, calcitonin gene–related peptide receptor antagonist that's been in development as a preventive treatment for chronic migraine, has been found to have fewer side effects and similar hepatic function profile to st...