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About 24,213 results

ALLMedicine™ Constipation Center

Research & Reviews  5,247 results

Clinical and imaging evidence of brain-first and body-first Parkinson's disease.
https://doi.org/10.1016/j.nbd.2022.105626
Neurobiology of Disease; Horsager J, Knudsen K et. al.

Jan 16th, 2022 - Braak's hypothesis has been extremely influential over the last two decades. However, neuropathological and clinical evidence suggest that the model does not conform to all patients with Parkinson's disease (PD). To resolve this controversy, a new...

Citric Acid-Enriched Extract of Ripe Prunus mume (Siebold) Siebold & Zucc. Induces Laxa...
https://doi.org/10.1089/jmf.2021.K.0138
Journal of Medicinal Food; Na JR, Kim E et. al.

Jan 15th, 2022 - Previously, we demonstrated that extracts of the ripe fruit (rPM) and unripe fruit (uPM) of Prunus mume (Siebold) Siebold & Zucc. and citric acid have a laxative effect, which is at least partially mediated by the increase in fecal parameters as s...

Nutrition, defecation, and the lower gastrointestinal tract during critical illness.
https://doi.org/10.1097/MCO.0000000000000814
Current Opinion in Clinical Nutrition and Metabolic Care; McClave SA

Jan 14th, 2022 - The goal of this report is to delineate the correlation between constipation as a manifestation of impaired gastrointestinal transit with adverse clinical outcomes, to identify risk factors, which predispose to this condition, and outline a manage...

Cost-effectiveness of physiotherapy in childhood functional constipation: a randomized ...
https://doi.org/10.1093/fampra/cmab147
Family Practice; van Summeren JJGT, Holtman GA et. al.

Jan 13th, 2022 - Health care expenditures for children with functional constipation (FC) are high, while conservative management is successful in only 50% of the children. The aim is to evaluate whether adding physiotherapy to conventional treatment (CT) is a cost...

Efficacy and Safety of Linaclotide in Patients with Irritable Bowel Syndrome with Const...
https://doi.org/10.1111/1751-2980.13081
Journal of Digestive Diseases; Peng L, Fang J et. al.

Jan 13th, 2022 - Linaclotide demonstrated potency in treating constipation-predominant irritable bowel syndrome (IBS-C), but few studies examined its use in Asian patients. Using data from a completed trial (NCT01880424), this sub-cohort analysis was performed to ...

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Guidelines  16 results

My Treatment Approach to Multiple System Atrophy.
https://doi.org/10.1016/j.mayocp.2020.10.005
Mayo Clinic Proceedings; Coon EA, Ahlskog JE

Mar 7th, 2021 - Multiple system atrophy (MSA) is a neurodegenerative disorder primarily characterized by autonomic failure plus parkinsonism or cerebellar ataxia. The diagnosis may be challenging and is usually made at a tertiary care center. The long-term manage...

European society of neurogastroenterology and motility guidelines on functional constip...
https://doi.org/10.1111/nmo.13762
Neurogastroenterology and Motility : the Official Journal... Serra J, Pohl D et. al.

Nov 23rd, 2019 - Chronic constipation is a common disorder with a reported prevalence ranging from 3% to 27% in the general population. Several management strategies, including diagnostic tests, empiric treatments, and specific treatments, have been developed. Our...

Medical Management of Opioid-Induced Constipation.
https://doi.org/10.1001/jama.2019.15852
JAMA Rao VL, Micic D et. al.

Nov 5th, 2019 - Medical Management of Opioid-Induced Constipation.|2019|Rao VL,Micic D,Davis AM,|adverse effects,therapeutic use,therapeutic use,therapeutic use,analogs & derivatives,therapeutic use,therapeutic use,drug therapy,therapeutic use,

MASCC recommendations on the management of constipation in patients with advanced cancer.
https://doi.org/10.1007/s00520-019-05016-4
Supportive Care in Cancer : Official Journal of the Multi... Davies A, Leach C et. al.

Aug 10th, 2019 - The Palliative Care Study Group of the Multinational Association for Supportive Care in Cancer formed a subgroup to develop evidence-based recommendations on the management of constipation in patients with advanced cancer. These recommendations we...

Opioid-Induced Constipation (OIC) Guideline.
https://doi.org/10.1053/j.gastro.2018.10.044
Gastroenterology Crockett S, Greer KB et. al.

Nov 6th, 2018 - Opioid-Induced Constipation (OIC) Guideline.|2018|Crockett S,Greer KB,Sultan S,|adverse effects,chemically induced,diagnosis,drug therapy,physiopathology,drug effects,standards,adverse effects,therapeutic use,adverse effects,therapeutic use,advers...

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Drugs  2,495 results see all →

Clinicaltrials.gov  474 results

Assessing GS500 in Functional Constipation
https://clinicaltrials.gov/ct2/show/NCT04887896

Jan 11th, 2022 - To evaluate the safety, tolerabilityand efficacy of GS500 as a superabsorbent hydrogel for relief of constipation in subjects with functional constipation.

Stimulation for Colonic Motility
https://clinicaltrials.gov/ct2/show/NCT02641483

Jan 6th, 2022 - The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogenic bowel dysfunction, which includes slowed colonic motility, which means that stools ta...

Effects of Xiangshao Granules on Anxiety in Menopausal Women.
https://clinicaltrials.gov/ct2/show/NCT05003336

Jan 3rd, 2022 - Symptoms of anxiety are prevalent during the menopausal transition and early postmenopause. These symptoms are mainly improved by anti-anxiety agents, which are associated with some adverse effects including dizziness, sleepiness, and constipation...

Encopresis & MIE (DoD #2)
https://clinicaltrials.gov/ct2/show/NCT03197922

Dec 20th, 2021 - Toilet training one's child is a nearly universal challenge for parents, but is a particularly distressing ordeal for parents of individuals with autism spectrum disorder (ASD). Whereas typically developing children generally stop having daytime t...

Quality of Life Among Egyptian Hypothyroid Patients
https://clinicaltrials.gov/ct2/show/NCT05143918

Dec 20th, 2021 - Hypothyroidism is an underactive thyroid gland. Hypothyroidism means that the thyroid gland can't make enough thyroid hormone to keep the body running normally. People are hypothyroid if they have too little thyroid hormone in the blood. Common ca...

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News  1,231 results

Clinical Edge Journal Scan Commentary: Migraine January 2022
https://www.mdedge.com/migraine-icymi/article/250655/headache-migraine/clinical-edge-journal-scan-commentary-migraine
Thomas Berk, MD

Jan 12th, 2022 - Ferrari et al 1provided information on an open label extension to the “LIBERTY” study which investigated the use of erenumab in subjects with episodic migraine that have failed multiple prior preventive medications. The initial Calcitonin gene-rel.

Ripretinib Approval Advances Recurrent GIST Paradigm
https://www.onclive.com/view/ripretinib-approval-advances-recurrent-gist-paradigm

Jan 3rd, 2022 - Ripretinib (Qinlock) has become the first therapy specifically approved for the fourth-line treatment of gastrointestinal stromal tumors, a clinical setting with an unmet medical need because of the poor prognosis of patients with progressive dise...

Selinexor Approved in China for Relapsed or Refractory Multiple Myeloma
https://www.onclive.com/view/selinexor-approved-in-china-for-relapsed-or-refractory-multiple-myeloma

Dec 22nd, 2021 - The China National Medical Products Administration has granted a conditional marketing approval to selinexor (Xpovio) for use in combination with dexamethasone in patients with relapsed or refractory multiple myeloma who have previously received t...

Axi-Cel Improves QoL in Second-Line Treatment of LBCL
https://www.onclive.com/view/axi-cel-improves-qol-in-second-line-treatment-of-lbcl

Dec 12th, 2021 - Axicabtagene ciloleucel (axi-cel; Yescarta), an autologous anti-CD19 CAR T-cell therapy, resulted in clinically meaningful improvement in quality of life (QoL) at day 100 compared with standard of care (SOC) as a second-line treatment of patients ...

Ibrutinib Plus R-Mini-CHOP Misses OS End Point but Shows Improved PFS in Newly Diagnosed DLBCL
https://www.onclive.com/view/ibrutinib-plus-r-mini-chop-misses-os-end-point-but-shows-improved-pfs-in-newly-diagnosed-dlbcl

Dec 12th, 2021 - Ibrutinib (Imbruvica) plus rituximab (Rituxan) and mini-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone [R-mini-CHOP]) failed to demonstrate a statistically significant improvement in overall survival (OS) at 2 years but led to an...

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Patient Education  222 results see all →