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About 75,890 results

ALLMedicine™ Diarrhea Center

Research & Reviews  17,032 results

On-target inhibition of Cryptosporidium parvum by nitazoxanide (NTZ) and paclitaxel (PT...
https://doi.org/10.1371/journal.pntd.0011217
PLoS Neglected Tropical Diseases; Yang B, Yan Y et. al.

Mar 28th, 2023 - Cryptosporidium parvum is a globally distributed zoonotic protozoan parasite that causes moderate to severe, sometime deadly, watery diarrhea in humans and animals, for which fully effective treatments are yet unavailable. In studying the mechanis...

Genome-wide association studies of diarrhea frequency and duration in the first year of...
https://doi.org/10.1093/infdis/jiad068
The Journal of Infectious Diseases; Munday RM, Haque R et. al.

Mar 28th, 2023 - Diarrhea is the second leading causing of death in children <5 worldwide. Known diarrhea risk factors include sanitation, water sources, and pathogens but do not fully explain the heterogeneity in frequency and duration of diarrhea in young childr...

Efficacy and Safety of Naldemedine Administration for Opioid-Induced Constipation in Ca...
https://doi.org/10.1089/jpm.2022.0495
Journal of Palliative Medicine; Fujita Y, Imai H et. al.

Mar 28th, 2023 - Background: Constipation is a concern among patients with Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 3 and 4. Objectives: To assess naldemedine's efficacy and safety in cancer patients on opioids with poor PS. Design: Mul...

Predictors of Adherence to Short-Course Probiotics Among Children with Gastroenteritis ...
https://doi.org/10.25011/cim.v46i1.39560
Clinical and Investigative Medicine. Medecine Clinique Et... Hurley KF, Fitzpatrick EA et. al.

Mar 27th, 2023 - To improve our understanding of adherence to discharge medications in the ED and within research trials, we sought to quantify medication adherence and identify predictors thereof in children with acute gastroenteritis (AGE). We conducted a second...

Diarrhea Don'ts: Reducing Inappropriate Stool Cultures and Ova and Parasite Testing for...
https://doi.org/10.1016/j.ajic.2023.03.011
American Journal of Infection Control; Garcia M, Krouss M et. al.

Mar 26th, 2023 - Diarrhea that develops in patients after 72 hours of hospitalization is likely to have a nosocomial or iatrogenic etiology. Testing with stool cultures and stool ova and parasites (O&P) is not recommended. Our goal was to reduce this inappropriate...

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Guidelines  21 results

AGA Clinical Practice Update on Alpha-Gal Syndrome for the GI Clinician: Commentary.
https://doi.org/10.1016/j.cgh.2022.12.035
Clinical Gastroenterology and Hepatology : the Official C... McGill SK, Hashash JG et. al.

Mar 24th, 2023 - Alpha-gal syndrome is an emerging allergy first described in the early 2000s. The allergy can cause anaphylaxis, gastrointestinal (GI) symptoms, and skin changes one to several hours after ingestion of mammalian products. A GI phenotype that is in...

AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Sy...
https://doi.org/10.1053/j.gastro.2022.04.017
Gastroenterology Lembo A, Sultan S et. al.

Jun 24th, 2022 - Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder associated with significant disease burden. This American Gastroenterological Association Guideline is intended to support practitioners in decisions about the use of ...

ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides diffici...
https://doi.org/10.14309/ajg.0000000000001278
The American Journal of Gastroenterology; Kelly CR, Fischer M et. al.

May 19th, 2021 - Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent ...

Blinded Oral Challenges with Lactose and Placebo Accurately Diagnose Lactose Intolerance: A Real-Life Study
https://pubmed.ncbi.nlm.nih.gov/34068318/
Nutrients Rocco A, Compare D et. al.

May 13th, 2021 - Lactose intolerance (LI) is characterized by diarrhea, abdominal pain, or bloating occurring after lactose consumption in patients with lactose malabsorption. The National Institute of Health (NIH) proposed a double-blind placebo testing to identi...

AGA Clinical Practice Update on Small Intestinal Bacterial Overgrowth: Expert Review.
https://doi.org/10.1053/j.gastro.2020.06.090
Gastroenterology Quigley EM, Murray JA et. al.

Jul 18th, 2020 - Thanks to ready access to hydrogen breath testing, small intestinal bacterial overgrowth is now commonly diagnosed among individuals presenting with a variety of gastrointestinal and even non-gastrointestinal complaints and is increasingly implica...

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Drugs  2,714 results see all →

Clinicaltrials.gov  1,891 results

Evaluation of Lactobacillus Reuteri DSM 17938 + Vitamin D3 in the Prevention of RRI in Paediatric Patients
https://clinicaltrials.gov/ct2/show/NCT04408443

Mar 23rd, 2023 - Several clinical trials documented the efficacy of probiotics in the prevention and treatment of acute gastroenteritis, while there is little evidence on the efficacy of the probiotics in the prevention of children respiratory infections. The biol...

A Multicentre French Prospective Study of Children With Food Protein Induced Enterocolitis Syndrome in Its Acute Form
https://clinicaltrials.gov/ct2/show/NCT05528900

Mar 17th, 2023 - Food protein induced enterocolitis syndrome (FPIES), is a non-IgE mediated food allergy (FA) which seems to expand, and occurring in infancy. Prevalence of FPIES is unknown. In 2011, Katz published cumulative incidence of cow 'milk FPIES of 3 per ...

Effects of COVID-19 on Endothelium in HIV-Positive Patients in Sub-Saharan Africa
https://clinicaltrials.gov/ct2/show/NCT04709302

Mar 10th, 2023 - Background: SARS-CoV-2 has affected almost every country worldwide with regard to health system capacities and economic burden, so far. The typical clinical presentations of COVID-19 are fever, sore through, cough, dyspnea, abdominal pain and diar...

Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors
https://clinicaltrials.gov/ct2/show/NCT04890093

Mar 10th, 2023 - Background: Irinotecan is a prodrug of an inhibitor of topoisomerase 1 (active metabolite is SN-38) with known activity in sarcomas, however it has limitations including suboptimal bioavailability and systemic side effects including severe diarrhe...

Effect of Iron Supplements on the Growth of Enteric Pathogens
https://clinicaltrials.gov/ct2/show/NCT05762380

Mar 9th, 2023 - Iron supplementation is a common approach to address iron deficiency with recommendations for women of childbearing age, particularly those at risk of iron deficiency. Because of its considerably higher absorption, ferrous sulphate is the common i...

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News  7,888 results

FDA Approves Long-Acting Antifungal for Treating Candida
https://www.medpagetoday.com/infectiousdisease/generalinfectiousdisease/103684

Mar 23rd, 2023 - The FDA gave the greenlight to the long-acting antifungal rezafungin (Rezzayo), the first new treatment option for candidemia and invasive candidiasis to gain approval in over a decade, Cidara Therapeutics and Melinta Therapeutics announced on Wed...

FDA OKs Another PD-1 Inhibitor for Merkel Cell Carcinoma
https://www.medpagetoday.com/hematologyoncology/skincancer/103661

Mar 22nd, 2023 - The second time proved to be the charm for the PD-1 inhibitor retifanlimab (Zynyz), as the FDA approved the drug for Merkel cell carcinoma (MCC). The agency had previously rejected an application from Incyte for approval of retifanlimab for locall...

Targeted Combination Gets FDA Nod for Pediatric Glioma
https://www.medpagetoday.com/hematologyoncology/braincancer/103585

Mar 17th, 2023 - The FDA announced on Thursday that it has approved the BRAF inhibitor dabrafenib (Tafinlar) combined with the MEK inhibitor trametinib (Mekinist) for the treatment of pediatric patients 1 year and older with low-grade glioma with a BRAF V600E muta...

Patient-based mouse MVID model hints at mechanism
https://www.mdedge.com/internalmedicine/article/261776/gastroenterology/patient-based-mouse-mvid-model-hints-mechanism
Jim Kling

Mar 13th, 2023 - Researchers have identified a novel mutation in a patient with microvillus inclusion disease (MVID) and rapidly developed a specific mouse model to find insights into the disease process. MVID is characterized by severe diarrhea, generally beginni.

First Treatment Approved for Rare Genetic Neurologic Disorder
https://www.medpagetoday.com/neurology/generalneurology/103503

Mar 13th, 2023 - The FDA approved trofinetide (Daybue), the first drug to treat adult and pediatric patients age 2 and older with Rett syndrome, drugmaker Acadia Pharmaceuticals announced Friday. "Now, for the first time after decades of clinical research, healthc...

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Patient Education  810 results see all →