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About 15,200 results

ALLMedicine™ Hepatitis C Virus Center

Research & Reviews  5,258 results

Risk of Non-Hodgkin's Lymphoma in HCV Patients in the United States Between 2013 and 20...
https://doi.org/10.1016/j.clml.2021.06.014
Clinical Lymphoma, Myeloma & Leukemia; Alkrekshi A, Kassem A et. al.

Aug 1st, 2021 - Hepatitis C virus (HCV) is a significant healthcare problem affecting ~1% of the United States population. Meta-analyses of epidemiological studies reported a strong association between non-Hodgkin's lymphoma (NHL) and HCV. Direct oncogenic proper...

Changes in health-related quality of life for HCV-infected people who inject drugs on o...
https://doi.org/10.1093/cid/ciab669
Clinical Infectious Diseases : an Official Publication Of... Gormley MA, Akiyama MJ et. al.

Aug 1st, 2021 - Although efforts to treat hepatitis C virus (HCV) in people who inject drugs (PWID) yield high rates of sustained virologic response (SVR), the relationship between successful HCV treatment and health-related quality of life (HRQOL) among PWID is ...

The Changing Epidemiology of Liver Disease Among US Children and Adolescents From 1999 ...
https://doi.org/10.14309/ajg.0000000000001386
The American Journal of Gastroenterology; Li J, Le MH et. al.

Jul 31st, 2021 - Nonalcoholic fatty liver disease (NAFLD) and infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) are major causes of liver disease in adults. However, data for children and adolescents are limited. Our study aimed to characterize the...

Antigenic and immunogenic evaluation of permutations of soluble hepatitis C virus envel...
https://doi.org/10.1371/journal.pone.0255336
PloS One; Prentoe J, Janitzek CM et. al.

Jul 31st, 2021 - Yearly, about 1.5 million people become chronically infected with hepatitis C virus (HCV) and for the 71 million with chronic HCV infection about 400,000 die from related morbidities, including liver cirrhosis and cancer. Effective treatments exis...

Mechanisms of HCV resistance to broadly neutralizing antibodies.
https://doi.org/10.1016/j.coviro.2021.07.003
Current Opinion in Virology; Frumento N, Flyak AI et. al.

Jul 31st, 2021 - Broadly neutralizing antibodies (bNAbs) block infection by genetically diverse hepatitis C virus (HCV) isolates by targeting relatively conserved epitopes on the HCV envelope glycoproteins, E1 and E2. Many amino acid substitutions conferring resis...

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Guidelines  9 results

EASL recommendations on treatment of hepatitis C: Final update of the series☆.
https://doi.org/10.1016/j.jhep.2020.08.018
Journal of Hepatology; , et. al.

Sep 22nd, 2020 - Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with approximately 71 million chronically infected individuals worldwide. Clinical care for patients with HCV-related liver disease has advanced considerably thanks to an...

Screening for Hepatitis C Virus Infection in Adolescents and Adults: US Preventive Serv...
https://doi.org/10.1001/jama.2020.1123
JAMA , Owens DK et. al.

Mar 3rd, 2020 - Hepatitis C virus (HCV) is the most common chronic blood-borne pathogen in the US and a leading cause of complications from chronic liver disease. HCV is associated with more deaths than the top 60 other reportable infectious diseases combined, in...

Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C Virus Infection in Chro...
https://doi.org/10.7326/M19-1539
Annals of Internal Medicine; Gordon CE, Berenguer MC et. al.

Sep 24th, 2019 - This article has been corrected. The original version (PDF) is appended to this article as a Supplement. The Kidney Disease: Improving Global Outcomes (KDIGO) 2018 clinical practice guideline for the prevention, diagnosis, evaluation, and treatmen...

Treatment of Chronic Hepatitis C Virus Infection in Children: A Position Paper by the H...
https://doi.org/10.1097/MPG.0000000000001872
Journal of Pediatric Gastroenterology and Nutrition; Indolfi G, Hierro L et. al.

Dec 30th, 2017 - In 2017, the European Medicines Agency and the Food and Drug Administration approved the use of the fixed-dose combination of ledipasvir/sofosbuvir and of the combination of sofosbuvir and ribavirin for treatment of adolescents (12-17 years or wei...

No. 96-The Reproductive Care of Women Living With Hepatitis C Infection.
https://doi.org/10.1016/j.jogc.2017.04.007
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Boucher M, Gruslin A

Jun 20th, 2017 - hepatitis C virus (HCV) is an increasingly important public health problem worldwide. Health care workers providing care to women of childbearing age are uniquely placed in their practices to identify a significant proportion of at-risk patients a...

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Drugs  18 results see all →

Clinicaltrials.gov  166 results

Oral Microbiome of Patients With Hepatitis C Virus Infection
https://clinicaltrials.gov/ct2/show/NCT03682549

Apr 24th, 2020 - Human oral cavity is a great habitat for more than 600 species of bacteria, known as oral microbiota, living in equilibrium. Oral microbiota plays an important role in maintaining oral health; however when the balance in oral bacterial population ...

Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection
https://clinicaltrials.gov/ct2/show/NCT00004850

Apr 22nd, 2020 - At initiation of this study in 1991, approximately 0.6% of U.S. blood donors were identified as having antibody to the hepatitis C virus (anti-HCV). This represented 72,000 of the estimated 12 million annual U.S. blood donations. By investigating ...

Direct Acting Antiviral-Post Authorization Safety Study
https://clinicaltrials.gov/ct2/show/NCT03707080

Apr 14th, 2020 - This is an independent optional sub-study parallel to TARGET-HCC (NCT02954094). The purpose of Direct-Acting Antiviral-Post Authorization Safety Study (DAA-PASS) is to investigate the impact of exposure to direct-acting antivirals (DAAs) on early ...

CHAMPS Study: Chronic HepAtitis C Management to ImProve OutcomeS
https://clinicaltrials.gov/ct2/show/NCT02402218

Apr 14th, 2020 - Recent advances in Hepatitis C Virus (HCV) treatment represent a paradigm shift for the treatment of HCV-infected persons with Human Immunodeficiency Virus (HIV) coinfection. With potent antiviral activity, excellent safety/tolerability, few drug ...

A Pilot Study of Treating HCV at a Psychiatrist-staffed Outpatient Addiction Clinic
https://clinicaltrials.gov/ct2/show/NCT03235154

Apr 2nd, 2020 - An estimated 3.2 million people in the United States are currently infected with hepatitis C virus (HCV). Since 1990, when the US introduced screening of the blood supply for HCV, injection drug use has been the primary mode of HCV transmission in...

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News  627 results

Rapid Core Antigen HCV Tests Could Expand Accessibility
https://www.medscape.com/viewarticle/954141

Jul 1st, 2021 - A proposed rapid diagnostic test for hepatitis C viral infections that combines an inexpensive but lower-sensitivity core-antigen test with lab RNA confirmation of negative tests could expand testing and same-day initiation of antiviral therapy in...

Fast Five Quiz: Are You Prepared to Confront Hepatitis C?
https://www.medscape.com/viewarticle/833773

Jun 4th, 2021 - Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). It is a major public health problem. Infection with HCV can lead to both acute and chronic hepatitis, varying in severity from a mild illness of short duration to a serious, lif...

Fast Five Quiz: Are You Prepared to Confront Hepatitis C?
https://reference.medscape.com/viewarticle/833773

Jun 4th, 2021 - Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). It is a major public health problem. Infection with HCV can lead to both acute and chronic hepatitis, varying in severity from a mild illness of short duration to a serious, lif...

Liver Transplant Outcomes Improving for US Patients With HIV/HCV
https://www.medscape.com/viewarticle/952065

May 28th, 2021 - While liver transplant outcomes were historically poor in people coinfected with HIV and hepatitis C virus (HCV), they have improved significantly in the era of direct-acting antiviral (DAA) therapy, a recent analysis of U.S. organ transplant data...

Drops in Hepatitis C Testing, Treatment Spark Concern
https://www.medscape.com/viewarticle/951421

May 19th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The COVID-19 pandemic has coincided with sharp declines in routine testing for and treatment of hepatitis C virus (HCV) infection, according to th...

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Patient Education  2 results see all →