ALLMedicine™ Hepatitis C Virus Center

Dec 2nd, 2021 - The early diagnosis of active hepatitis C virus (HCV) infection remains a significant barrier to the treatment of the disease and to preventing the associated significant morbidity and mortality seen, worldwide. Current testing is delayed due to t...

Dec 1st, 2021 - Hepatitis C virus (HCV) continues to pose significant public health concerns with approximately 44% of chronically infected Canadians undiagnosed. The current HCV screening in Canada is a two-step diagnosis pathway consisting of anti-HCV testing a...

Nov 30th, 2021 - Unconventional T cells (UTCs) are a heterogenous group of T cells that typically exhibit rapid responses towards specific antigens from pathogens. Chronic hepatitis C virus (HCV) infection causes dysfunction of several subsets of UTCs. This altere...

Nov 27th, 2021 - The Rab GTPase family contains almost 70 genes in the human genome and acts as the key regulator of intracellular membrane trafficking in human cells. The dysregulation of Rab GTPase has been shown to be associated with multiple human diseases, ra...

Nov 27th, 2021 - microRNAs (miRNAs) form regulatory networks in metazoans. Viruses engage miRNA networks in numerous ways, with Flaviviridae members exploiting direct interactions of their RNA genomes with host miRNAs. For hepatitis C virus (HCV), binding of liver...

Aug 1st, 2021 - Hepatitis C virus (HCV) infection is a major cause of chronic liver disease. Clinical care for patients with HCV-related liver disease has advanced considerably with developments in screening, diagnostic procedures to evaluate liver fibrosis and i...

Sep 22nd, 2020 - Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with approximately 71 million chronically infected individuals worldwide. Clinical care for patients with HCV-related liver disease has advanced considerably thanks to an...

Mar 3rd, 2020 - Hepatitis C virus (HCV) is the most common chronic blood-borne pathogen in the US and a leading cause of complications from chronic liver disease. HCV is associated with more deaths than the top 60 other reportable infectious diseases combined, in...

Sep 24th, 2019 - This article has been corrected. The original version (PDF) is appended to this article as a Supplement. The Kidney Disease: Improving Global Outcomes (KDIGO) 2018 clinical practice guideline for the prevention, diagnosis, evaluation, and treatmen...

Sep 27th, 2018 - Hepatitis C virus (HCV) infection is now considered a systemic disease due to the occurrence of extra-hepatic manifestations. Among these, the renal involvement is frequent. HCV infection, in fact, is strongly associated with proteinuria and chron...

Nov 17th, 2021 - Although the risk for liver cancer diminishes for patients with hepatitis C virus (HCV) infections for whom virus is eliminated with direct-acting antiviral (DAA) drugs, these patients are not out of the woods, and those who do not have a sustaine...

Nov 3rd, 2021 - Rates of hepatitis C virus (HCV) infections fell to 0.6% among gay and bisexual men living with HIV after a systematic HCV elimination campaign, showing that micro-elimination campaigns paired with continued testing and treatment is effective in a...

Jul 20th, 2021 - Avenir HIV/AIDs recipient Matthew Akiyama, MD, an assistant professor and clinician-investigator at the Albert Einstein College of Medicine, in New York City, is a blood-borne infections sleuth. Dr Matthew Akiyama With a 4-year, $2.5M Avenir Award...

Jul 1st, 2021 - A proposed rapid diagnostic test for hepatitis C viral infections that combines an inexpensive but lower-sensitivity core-antigen test with lab RNA confirmation of negative tests could expand testing and same-day initiation of antiviral therapy in...

Jun 4th, 2021 - Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). It is a major public health problem. Infection with HCV can lead to both acute and chronic hepatitis, varying in severity from a mild illness of short duration to a serious, lif...