About 43,530 results

ALLMedicine™ Inflammatory Bowel Disease Center

Research & Reviews  14,384 results

Alterations in the Course of Inflammatory Bowel Disease Following Liver Transplantation...
Inflammatory Bowel Diseases; Safarpour AR, Shojaei-Zarghani S et. al.

Jul 3rd, 2022 - This study aimed to systematically review and pool data regarding the alterations in the clinical course of inflammatory bowel disease (IBD) following liver transplantation (LT). Relevant prospective and retrospective observational studies were id...

Timing of live attenuated vaccination in infants exposed to infliximab or adalimumab in...
Journal of Crohn's & Colitis; Liu Z, Julsgaard M et. al.

Jul 3rd, 2022 - For infants exposed in utero to anti-tumour necrosis factor-a (TNF) medications, it is advised that live-attenuated vaccinations be postponed until drug is cleared, but little is known about time to clearance. To minimize delays before live-attenu...

Primary Care Professionals' Attitudes Towards Vaccination Recommendation for Patients W...
Inflammatory Bowel Diseases; Xu F, deJong N et. al.

Jul 3rd, 2022 - Immunization among patients with inflammatory bowel disease (IBD) is suboptimal. We sought to characterize attitudes of US primary care professionals (PCPs) towards immunization practices for patients with IBD. Using a web-based opt-in panel of PC...

Sensitisation of colonic nociceptors by TNFα is dependent on TNFR1 expression and p38 M...
The Journal of Physiology; Barker KH, Higham JP et. al.

Jul 2nd, 2022 - The pro-inflammatory cytokine TNFα is elevated in GI disease and sensitises colonic afferents via modulation of TRPA1 and NaV 1.8 activity. We further develop this understanding by demonstrating a role for p38 MAPK and TRPV1 in TNFα mediated colon...

Immunosurveillance of Candida albicans commensalism by the adaptive immune system.
https://doi.org/10.1038/s41385-022-00536-5 10.1016/j.medmal.2015.01.007 10.1016/j.immuni.2015.10.023 10.1016/j.chom.2016.05.003 10.1038/nri.2017.55 10.1038/nrdp.2018.26 10.1016/j.immuni.2019.05.023 10.1146/annurev-immunol-042617-053318 10.3390/pathogens8020054 10.1038/s41564-021-00983-z 10.3389/fimmu.2020.555363 10.1038/s41586-021-03722-w 10.1038/ni1467 10.1016/j.cell.2019.01.041 10.1126/science.1260668 10.1016/j.jaci.2017.09.042 10.1084/jem.20081463 10.1038/s41385-020-0327-1 10.4049/jimmunol.1202924 10.1038/mi.2017.2 10.1126/sciimmunol.aam8834 10.1016/j.immuni.2015.08.016 10.1371/journal.ppat.1007069 10.1016/j.immuni.2015.01.008 10.1016/j.immuni.2011.06.005 10.1371/journal.ppat.1005164 10.1146/annurev.immunol.021908.132710 10.1146/annurev-immunol-093019-112348 10.1016/j.immuni.2019.05.004 10.1126/sciimmunol.abb6808 10.1073/pnas.1912432116 10.1016/j.cell.2022.01.017 10.1126/science.aay5731 10.1016/j.chom.2019.02.004 10.1126/science.aat0537 10.1038/nature20818 10.1038/s41586-019-1843-6 10.1126/science.aad0314 10.1038/s41590-020-0776-4 10.1186/s40168-017-0242-1 10.1007/s10803-020-04543-y 10.3389/fimmu.2019.00330 10.4049/jimmunol.1302265 10.1038/mi.2014.57 10.3389/fimmu.2021.670290 10.1016/j.it.2020.03.006 10.1038/s41385-019-0223-8 10.1038/s41385-019-0192-y 10.1038/nri2939 10.1172/jci.insight.93156 10.1038/s41564-017-0059-5 10.1016/j.celrep.2019.06.020 10.1016/j.femsim.2004.03.012 10.1016/j.immuni.2019.07.001 10.1146/annurev.immunol.26.021607.090248 10.1016/j.cell.2021.01.016 10.1126/science.aao1503 10.1111/jcmm.14770 10.1186/s12950-018-0189-4 10.1111/j.1572-0241.2005.00361.x 10.1097/MEG.0b013e3282f824c9 10.1371/journal.ppat.1005293 10.1038/s41590-019-0377-2 10.1016/j.it.2019.01.005 10.1038/mi.2011.41 10.4161/19490976.2014.983763 10.1038/nature22058 10.1080/21505594.2021.2015116 10.1038/mi.2007.14 10.1111/imcb.12412 10.1038/s41586-020-2886-4 10.1038/s41385-019-0227-4 10.1016/j.clim.2017.07.020 10.4049/jimmunol.1601572 10.3389/fimmu.2021.698849 10.1101/gr.174623.114 10.1038/s41467-018-04787-4 10.1128/EC.00387-08 10.1371/journal.ppat.1003315 10.1128/mBio.02878-21 10.1038/nm.3871 10.1128/mSphere.00393-20 10.1038/nmicrobiol.2016.238 10.1073/pnas.1109631108 10.1534/genetics.118.301019 10.1371/journal.pgen.1008137 10.1038/s41598-019-38768-4 10.3390/pathogens7010011 10.1073/pnas.2003022117 10.1001/archderm.1984.01650400017002 10.1016/j.chom.2019.02.002 10.1097/MIB.0000000000000454 10.1128/mBio.01250-16 10.1097/MCG.0000000000000035 10.1093/ecco-jcc/jjv209 10.1136/gutjnl-2015-310746 10.1038/ajg.2009.225 10.1038/s41586-022-04502-w 10.1136/annrheumdis-2020-217927 10.1016/j.cell.2019.11.026 10.1016/j.immuni.2016.02.007 10.1016/j.chom.2017.10.013 10.1016/j.mib.2020.09.008 10.4049/jimmunol.1200594 10.1136/gut.31.5.536 10.1097/00054725-200102000-00002 10.1053/j.gastro.2006.02.009 10.1002/ibd.20228 10.1086/528990 10.1016/j.chom.2019.01.007 10.1136/gut.2004.060228 10.1016/j.chom.2015.09.008 10.3389/fphys.2021.699253 10.1172/JCI90562 10.1002/hep.30832 10.1016/j.jhep.2021.11.029 10.1038/s41423-020-00568-6 10.1038/icb.2010.72 10.1084/jem.20091669 10.1084/jem.20091983 10.1172/jci.insight.88782 10.1210/jc.2017-00139 10.1126/science.abi8835 10.1016/j.vaccine.2016.10.025 10.1128/JCM.44.5.1810-1820.2006 10.3389/fimmu.2018.00897 10.1056/NEJMra1315399 10.1371/journal.ppat.1006056 10.1371/journal.ppat.1000703 10.1016/j.vaccine.2012.10.038 10.1038/s41598-019-42517-y 10.1016/j.vaccine.2013.09.016 10.1086/504691 10.1371/journal.ppat.1007460 10.1093/cid/ciy185 10.1128/iai.63.7.2619-2624.1995 10.1128/IAI.71.6.3227-3234.2003 10.1016/j.molimm.2009.08.019 10.1016/j.imlet.2015.08.009 10.1128/iai.65.8.3399-3405.1997 10.3390/vaccines9101159 10.15698/mic2021.09.759 10.1038/s41467-021-21361-7 10.1038/s41423-020-00530-6
Mucosal Immunology; Swidergall M, LeibundGut-Landmann S

Jul 2nd, 2022 - The fungal microbiota (mycobiota) is an integral part of the microbial community colonizing the body surfaces and is involved in many key aspects of human physiology, while an imbalance of the fungal communities, termed fungal dysbiosis, has been ...

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Guidelines  43 results

AGA Clinical Practice Update on Endoscopic Surveillance and Management of Colorectal Dy...
Gastroenterology Murthy SK, Feuerstein JD et. al.

Aug 22nd, 2021 - Improvements in disease management, as well as endoscopic technology and quality, have dramatically changed the way in which we conceptualize and manage inflammatory bowel disease-related dysplasia over the past 20 years. Based on evolving literat...

Canadian Association of Gastroenterology Clinical Practice Guideline for Immunizations ...
Gastroenterology Jones JL, Tse F et. al.

Aug 3rd, 2021 - The effectiveness and safety of vaccinations can be altered by immunosuppressive therapies, and perhaps by inflammatory bowel disease (IBD) itself. These recommendations developed by the Canadian Association of Gastroenterology and endorsed by the...

Non-invasive diagnosis and follow-up of primary sclerosing cholangitis.
Clinics and Research in Hepatology and Gastroenterology; Chazouillères O, Potier P et. al.

Aug 1st, 2021 - Primary sclerosing cholangitis (PSC) is a rare and chronic cholestatic liver disease of unknown cause commonly associated with inflammatory bowel disease (IBD) and characterized by progressive obliterative fibro-inflammation of the biliary tree. A...

WSES-AAST guidelines: management of inflammatory bowel disease in the emergency setting.
World Journal of Emergency Surgery : WJES; De Simone B, Davies J et. al.

May 12th, 2021 - Despite the current therapeutic options for the treatment of inflammatory bowel disease, surgery is still frequently required in the emergency setting, although the number of cases performed seems to have decreased in recent years. The World Socie...

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammat...
Journal of Crohn's & Colitis; Kucharzik T, Ellul P et. al.

Mar 18th, 2021 - ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease.|2021|Kucharzik T,Ellul P,Greuter T,Rahier JF,Verstockt B,|adverse effects,therapeutic use,complications,drug therapy,immunology,complications...

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Drugs  37 results see all →

Clinicaltrials.gov  1,101 results

Clinical and Molecular Phenotyping in IBD

Jul 1st, 2022 - Inflammatory bowel disease (IBD) and psoriasis (Ps) are common, chronic, immune- mediated barrier diseases with shared inflammatory pathways. Current therapeutic interventions with anti-cytokine antibodies (TNF-α, IL-23/IL-12) reflect the intent t...

Natural History and Development of Spondyloarthritis

Jul 1st, 2022 - The purpose of this protocol is to study the natural history of spondyloarthritis (SpA) in children and adults. Spondyloarthritis encompasses a spectrum of immune-mediated inflammatory diseases that exhibit overlapping features, but differ from ot...

An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab

Jul 1st, 2022 - Crohn s Disease (CD), a major sub-type of inflammatory bowel disease (IBD), is a chronic, life-long condition characterized by relapsing inflammation of the gastrointestinal (GI) tract. Despite recent advances in IBD therapeutics, a significant nu...

Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide

Jul 1st, 2022 - Allogeneic transplant using human leukocyte antigen (HLA) matched donors, both related and unrelated, has proven curative for patients with various immunodeficiencies, including those with ongoing infections. However, donor availability remains a ...

Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous Disease

Jul 1st, 2022 - Chronic granulomatous disease (CGD) is a rare genetic immune disorder that results in recurrent and severe infections, and inflammatory dysregulation. For almost 50% of patients with CGD, this inflammation causes severe inflammatory bowel disease ...

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News  1,802 results

Exocrine Pancreatic Insufficiency: Risk Factors and Management Approaches
Jodie Barkin, MD,, MDedge News

Jul 1st, 2022 - What characteristics or symptoms do you look for to identify patients who are at risk for exocrine pancreatic insufficiency (EPI)? Dr. Barkin: The first thing we have to understand is which patient populations we should consider.

No Support for Proactive Therapeutic Drug Monitoring in IBD

Jul 1st, 2022 - NEW YORK (Reuters Health) - Studies to date have failed to demonstrate a clinical benefit of routine proactive therapeutic drug monitoring (TDM) in patients with inflammatory bowel disease (IBD) treated with tumor necrosis factor-alpha (TNFa) anta...

Commentary: Caring for Patients With IBD, July 2022
Marita Kametas, MSN, FNP-BC, CMSRN, COCN

Jun 29th, 2022 - Marita Kametas, MSN, FNP-BC, CMSRN, COCN The importance of cancer screening and prevention in patients with inflammatory bowel disease (IBD) is highlighted by the study of Wu and colleagues. Patients who are taking immunosuppressive therapy shoul.

IBD: Frequent consumption of processed meat tied to increased mortality risk

Jun 29th, 2022 - Key clinical point: Patients with inflammatory bowel disease (IBD) who consumed processed meat more frequently had a higher mortality risk; however, no such association was observed for the consumption of other types of meat. Major finding: The ri.

IBD: Intradermal HBV vaccination with topical imiquimod safe and effective

Jun 29th, 2022 - Key clinical point: Intradermal (ID) hepatitis B virus (HBV) vaccination with topical imiquimod pretreatment (ID-Imq) to the injection site was safe and provided superior seroprotection compared with intramuscular (IM) HBV vaccination with aqueous.

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Patient Education  45 results see all →