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About 3,843 results

ALLMedicine™ Acute Liver Failure Center

Research & Reviews  1,395 results

Exosomes derived from human umbilical cord mesenchymal stem cells alleviate acetaminoph...
https://doi.org/10.1016/j.jphs.2021.06.008
Journal of Pharmacological Sciences; Wu HY, Zhang XC et. al.

Jul 23rd, 2021 - This study aimed to investigate the therapeutic potential of human umbilical cord mesenchymal stem cells derived exosomes (hUCMSC-Exo) in acute liver failure (ALF) in mice as well as its underlying mechanism. We found that a single tail vein admin...

Hypophosphatemia in acute liver failure of a broad range of etiologies is associated wi...
https://doi.org/10.1016/j.trsl.2021.07.003
Translational Research : the Journal of Laboratory and Cl... Zechner C, Adams-Huet B et. al.

Jul 23rd, 2021 - Hypophosphatemia is a common and dangerous complication of acute liver failure (ALF) of various etiologies. While various mechanisms for ALF-associated hypophosphatemia have been proposed including high phosphate uptake into regenerating hepatocyt...

Resolution of recurrent pediatric acute liver failure with liver transplantation in a p...
https://doi.org/10.1111/petr.14084
Pediatric Transplantation; Geem D, Jiang W et. al.

Jul 21st, 2021 - Pediatric acute liver failure (PALF) remains an enigmatic process of rapid end-organ dysfunction associated with a variety of pathologic conditions though the predominant cause is indeterminate. A growing body of research has identified mutations ...

Intestinal Autotransplantation and In-Situ Resection of Recurrent Pancreatic Head Intra...
https://doi.org/10.1016/j.transproceed.2021.05.009
Transplantation Proceedings; Raveh Y, Beduschi T et. al.

Jul 18th, 2021 - Intraductal tubulopapillary neoplasm (ITPN) is a new entity of a rare premalignant pancreatic neoplasia, and a radical curative resection is indicated. As with other tumors of the root of the mesentery, the proximity of the lesion to large splanch...

First Pediatric Case Report of an Acute Liver Failure as a Complication of Brucellosis.
https://doi.org/10.1093/jpids/piab055
Journal of the Pediatric Infectious Diseases Society; Çakar S, Eren G et. al.

Jul 16th, 2021 - First Pediatric Case Report of an Acute Liver Failure as a Complication of Brucellosis.|2021|Çakar S,Eren G,Gülfidan G,Ömür Ecevit Ç,Bekem Ö,|

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Drugs  24 results see all →

Clinicaltrials.gov  22 results

A Multi-Center Trial to Study Acute Liver Failure in Adults
https://clinicaltrials.gov/ct2/show/NCT00518440

Mar 8th, 2020 - Although ALF is truly an orphan disease affecting only about 2,000 persons per year, its severity, its frequency among young adults, and its high resource utilization justifies the attention paid to it. In addition, ALF has captured the interest a...

To Assess the Role of Fecal Microbiota Transplant in Acute Liver Failure
https://clinicaltrials.gov/ct2/show/NCT03363022

Nov 4th, 2019 - All patients of Acute liver failure not meeting the KCH (King's College Hospital) criteria/or meeting KCH criteria not having option of liver transplant will be recruited for the trial. The first group will receive Standard medical care with Fecal...

36 Weeks Short-Term Optimization Treatment of Glucocorticosteroid in the Patients With Chronic Recurrent DILI
https://clinicaltrials.gov/ct2/show/NCT03266146

Jan 29th, 2019 - Drug-induced liver injury (DILI) refers to liver diseases caused by drugs and toxic substances. DILI is a clinical event that can be associated with severe outcomes such as acute liver failure. Up to now, approximately 1100 drugs, herbal products,...

Hepatocyte Transplantation for Acute Decompensated Liver Failure
https://clinicaltrials.gov/ct2/show/NCT01345565

Jan 22nd, 2019 - Orthotopic liver transplantation has become the treatment of choice for patients with acute liver failure with poor prognostic signs. Survival following hepatic transplantation has improved in the last decade for a number of reasons. These include...

Plasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson's Disease-related Liver Failure
https://clinicaltrials.gov/ct2/show/NCT03589820

Jul 17th, 2018 - Wilson's disease (WD) is an inherited disorder in which defective biliary excretion of copper leads to its accumulation, particularly in liver and brain. Presenting symptoms of liver disease can be highly variable, ranging from asymptomatic, with ...

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News  90 results

Liver Failure Management in the ICU: Clinical Practice Guidelines (2020)
https://reference.medscape.com/viewarticle/925736

Feb 27th, 2020 - In February 2020, a panel from the Society of Critical Care Medicine published clinical practice management guidelines on adult acute and acute-on-chronic liver failure, as encountered in the intensive care unit (ICU).[1] For patients with acute l...

Inner demons
https://www.mdedge.com/gihepnews/article/212611/mixed-topics/inner-demons?channel=41022

Dec 1st, 2019 - Julia Brennan sings about inner demons. They just won’t go away and they don’t play fair with angels.

Blocking TLR9 may halt brain edema in acute liver failure
https://www.mdedge.com/gihepnews/article/211698/liver-disease/blocking-tlr9-may-halt-brain-edema-acute-liver-failure?channel=346
Will Pass, MDedge News

Nov 6th, 2019 - A toll-like receptor 9 (TLR9) antagonist may eventually be used to combat brain edema in acute liver failure, according to investigators. This prediction is based on results of a recent study involving mouse models, which showed that ODN2088, a TL.

Infusion of Evidence: The Albumin Effect in Cirrhosis Becomes Clearer
https://www.medscape.com/viewarticle/915323

Jul 9th, 2019 - Patients with cirrhosis have a significant reduction in cardiovascular and cardiopulmonary function. Arteriolar dilation, particularly in the splanchnic circulation, leads to a lessened arterial volume with a subsequent reduction in cardiac output...

Young, angry, and in need of a liver transplant
https://www.mdedge.com/psychiatry/article/199883/bipolar-disorder/young-angry-and-need-liver-transplant/page/0/2?channel=41019

May 1st, 2019 - At Visit 2 in the ED, Ms. L was started on NAC because the team suspected she was experiencing drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.

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Patient Education  6 results see all →