ALLMedicine™ Acute Liver Failure Center

Jan 18th, 2021 - Azoxymethane (AOM) is a widely used carcinogen to study chemical-induced colorectal carcinogenesis and is an agent for studying fulminant hepatic failure. The inter-strain susceptibility to acute toxicity by AOM has been reported, but its associat...

Jan 15th, 2021 - A 10-year-old male child, previously well and developmentally normal, was referred to us with history of abdominal pain associated with multiple episodes of bile-stained vomiting and lethargy for 7 days. He was afebrile and had periorbital puffine...

Jan 14th, 2021 - Acetaminophen (APAP) hepatotoxicity is the most frequent cause of acute liver failure in the US. The mechanisms of APAP-induced liver injury have been under extensive investigations for decades and many key events of this necrotic cell death are k...

Jan 12th, 2021 - Sickle cell disease is a group of autosomal recessive disorders characterised by haemolytic anaemia. Liver is one of the most affected organs, ranging from liver tests alterations to acute liver failure for which liver transplantation is the only ...

Jan 11th, 2021 - Since regenerating islet-derived 3β (Reg3β) was first reported, various studies have been conducted to explore the involvement of Reg3β in a gamut of maladies, such as diabetes, pancreatitis, pancreatic ductal adenocarcinoma, and extrapancreatic m...

Jan 5th, 2017 - American Gastroenterological Association Institute Guidelines for the Diagnosis and Management of Acute Liver Failure.|2017|Flamm SL,Yang YX,Singh S,Falck-Ytter YT, ,|standards,standards,diagnosis,etiology,therapy,standards,

Feb 29th, 2012 - Acute liver failure (ALF) is a rare condition in which rapid deterioration of liver function results in altered mentation and coagulopathy in individuals without known pre-existing liver disease. U.

Dec 1st, 2011 - In patients who do not respond to a volume challenge and norepinephrine, vasopressin and its analogues may potentiate the effects of norepinephrine and allow a decrease in its infusion rate, which in turn may avoid intense vasoconstriction in peri.

Jul 29th, 2009 - Objectives of the International Society for Hepatic Encephalopathy and Nitrogen Metabolism Commission were to identify well-characterized animal models of hepatic encephalopathy (HE) and to highlight areas of animal modelling of the disorder that ...

Jun 12th, 2009 - Parenteral nutrition (PN) offers the possibility to increase or to ensure nutrient intake in patients, in whom sufficient nutrition by oral or enteral alone is insufficient or impossible. Complementary to the ESPEN guideline on enteral nutrition o...

Jan 18th, 2021 - Azoxymethane (AOM) is a widely used carcinogen to study chemical-induced colorectal carcinogenesis and is an agent for studying fulminant hepatic failure. The inter-strain susceptibility to acute toxicity by AOM has been reported, but its associat...

Jan 15th, 2021 - A 10-year-old male child, previously well and developmentally normal, was referred to us with history of abdominal pain associated with multiple episodes of bile-stained vomiting and lethargy for 7 days. He was afebrile and had periorbital puffine...

Jan 14th, 2021 - Acetaminophen (APAP) hepatotoxicity is the most frequent cause of acute liver failure in the US. The mechanisms of APAP-induced liver injury have been under extensive investigations for decades and many key events of this necrotic cell death are k...

Jan 12th, 2021 - Sickle cell disease is a group of autosomal recessive disorders characterised by haemolytic anaemia. Liver is one of the most affected organs, ranging from liver tests alterations to acute liver failure for which liver transplantation is the only ...

Jan 11th, 2021 - Since regenerating islet-derived 3β (Reg3β) was first reported, various studies have been conducted to explore the involvement of Reg3β in a gamut of maladies, such as diabetes, pancreatitis, pancreatic ductal adenocarcinoma, and extrapancreatic m...

Nov 22nd, 2020 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety alert with updated advice on liver function testing for patients receiving pirfenidone (Esbriet). The alert follows a recent European safety review that identi...

Feb 27th, 2020 - In February 2020, a panel from the Society of Critical Care Medicine published clinical practice management guidelines on adult acute and acute-on-chronic liver failure, as encountered in the intensive care unit (ICU).[1] For patients with acute l...

Nov 6th, 2019 - A toll-like receptor 9 (TLR9) antagonist may eventually be used to combat brain edema in acute liver failure, according to investigators. This prediction is based on results of a recent study involving mouse models, which showed that ODN2088, a TL.

May 1st, 2019 - At Visit 2 in the ED, Ms. L was started on NAC because the team suspected she was experiencing drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.

Mar 28th, 2019 - Various treatment protocols for acetaminophen toxicity are available, depending on the institution and the poison control center. For intravenous treatment (used in pregnant women, altered mental status, acetaminophen-induced liver failure, and in...