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About 2,439 results

ALLMedicine™ Alcoholic Hepatitis Center

Research & Reviews  1,163 results

Changes in Serum Myostatin Levels in Alcoholic Hepatitis Correlate with Improvement in ...
https://doi.org/10.1007/s10620-020-06632-5
Digestive Diseases and Sciences; Shamseddeen H, Madathanapalli A et. al.

Oct 19th, 2020 - Alcoholic hepatitis (AH) is a serious clinical syndrome often associated with muscle wasting. Myostatin, a member of the transforming growth factor-β superfamily, has been studied in diseases with muscle wasting; however, the role of myostatin in ...

Non-invasive diagnosis of severe alcoholic hepatitis: Usefulness of cross-sectional ima...
https://doi.org/10.1016/j.diii.2020.09.009
Diagnostic and Interventional Imaging; Grillet F, Calame P et. al.

Oct 18th, 2020 - To describe the computed tomography (CT) and magnetic resonance imaging (MRI) features of severe acute alcoholic hepatitis (SAAH) and estimate the capabilities of CT and MRI in differentiating SAAH from alcoholic cirrhosis and non-alcoholic steato...

Alcoholic hepatitis and metabolic disturbance in female mice : a more tractable model t...
https://doi.org/10.1242/dmm.046383
Disease Models & Mechanisms; Sheriff L, Khan RS et. al.

Oct 17th, 2020 - Alcoholic hepatitis (AH) is the dramatic acute presentation of alcoholic liver disease, with a 28-day mortality of 15% in severe cases. Research into AH has been hampered by the lack of effective and reproducible murine models that can be operated...

Predictors of steroid non-response and new approaches in severe alcoholic hepatitis.
https://doi.org/10.3350/cmh.2020.0196
Clinical and Molecular Hepatology; Sarin SK, Sharma S

Oct 15th, 2020 - Severe alcoholic hepatitis (SAH) remains a disease with high mortality. Steroid is the main stay and has been shown to give modest 28-day survival benefit in carefully selected patients, but no 90-day survival benefit. Since non-responders have hi...

Nonalcoholic fatty liver disease and alcohol-related liver disease: From clinical aspec...
https://doi.org/10.3350/cmh.2020.0202
Clinical and Molecular Hepatology; Ikejima K, Kon K et. al.

Oct 15th, 2020 - Two major causes of steatohepatitis are alcohol and metabolic syndrome. Although the underlying causes of alcoholrelated liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) differ, there are certain...

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Guidelines  7 results

EASL Clinical Practice Guidelines: Management of alcohol-related liver disease
https://www.journal-of-hepatology.eu/article/S0168-8278(18)30214-9/fulltext
European Association for the Study of the Liver

Jun 30th, 2018 - The harmful use of alcohol has been estimated to cause approximately 3. 3?million deaths every year, corresponding to nearly 6% of all deaths globally.

ACG Clinical Guideline: Alcoholic Liver Disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524956
The American Journal of Gastroenterology; Singal AK, Bataller R et. al.

Jan 17th, 2018 - Alcoholic liver disease (ALD) comprises a clinical-histologic spectrum including fatty liver, alcoholic hepatitis (AH), and cirrhosis with its complications. Most patients are diagnosed at advanced stages and data on the prevalence and profile of ...

Medical Management of Severe Alcoholic Hepatitis: Expert Review from the Clinical Practice Updates Committee of the AGA Institute
https://www.cghjournal.org/article/S1542-3565(16)30798-4/fulltext?code=yjcgh-site

Apr 16th, 2017 - The purpose of this clinical practice update is to review diagnostic criteria for severe acute alcoholic hepatitis and to determine the current best practices for this life-threatening condition. The best practices in this review are based on clin...

Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alco...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287362
Gastroenterology Crabb DW, Bataller R et. al.

Feb 27th, 2016 - Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia.|2016|Crabb DW,Bataller R,Chalasani NP,Kamath PS,Lucey M,|classification,standards,...

Acute alcoholic hepatitis, end stage alcoholic liver disease and liver transplantation:...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209530
World Journal of Gastroenterology; Testino G, Burra P et. al.

Oct 30th, 2014 - Alcoholic liver disease encompasses a broad spectrum of diseases ranging from steatosis steatohepatitis, fibrosis, and cirrhosis to hepatocellular carcinoma. Forty-four per cent of all deaths from cirrhosis are attributed to alcohol. Alcoholic liv...

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Clinicaltrials.gov  1,199 results

Changes in Serum Myostatin Levels in Alcoholic Hepatitis Correlate with Improvement in ...
https://doi.org/10.1007/s10620-020-06632-5
Digestive Diseases and Sciences; Shamseddeen H, Madathanapalli A et. al.

Oct 19th, 2020 - Alcoholic hepatitis (AH) is a serious clinical syndrome often associated with muscle wasting. Myostatin, a member of the transforming growth factor-β superfamily, has been studied in diseases with muscle wasting; however, the role of myostatin in ...

Non-invasive diagnosis of severe alcoholic hepatitis: Usefulness of cross-sectional ima...
https://doi.org/10.1016/j.diii.2020.09.009
Diagnostic and Interventional Imaging; Grillet F, Calame P et. al.

Oct 18th, 2020 - To describe the computed tomography (CT) and magnetic resonance imaging (MRI) features of severe acute alcoholic hepatitis (SAAH) and estimate the capabilities of CT and MRI in differentiating SAAH from alcoholic cirrhosis and non-alcoholic steato...

Alcoholic hepatitis and metabolic disturbance in female mice : a more tractable model t...
https://doi.org/10.1242/dmm.046383
Disease Models & Mechanisms; Sheriff L, Khan RS et. al.

Oct 17th, 2020 - Alcoholic hepatitis (AH) is the dramatic acute presentation of alcoholic liver disease, with a 28-day mortality of 15% in severe cases. Research into AH has been hampered by the lack of effective and reproducible murine models that can be operated...

Predictors of steroid non-response and new approaches in severe alcoholic hepatitis.
https://doi.org/10.3350/cmh.2020.0196
Clinical and Molecular Hepatology; Sarin SK, Sharma S

Oct 15th, 2020 - Severe alcoholic hepatitis (SAH) remains a disease with high mortality. Steroid is the main stay and has been shown to give modest 28-day survival benefit in carefully selected patients, but no 90-day survival benefit. Since non-responders have hi...

Nonalcoholic fatty liver disease and alcohol-related liver disease: From clinical aspec...
https://doi.org/10.3350/cmh.2020.0202
Clinical and Molecular Hepatology; Ikejima K, Kon K et. al.

Oct 15th, 2020 - Two major causes of steatohepatitis are alcohol and metabolic syndrome. Although the underlying causes of alcoholrelated liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) differ, there are certain...

see more →

News  63 results

Serum keratin 18 promising as AAH biomarker
https://www.mdedge.com/gihepnews/article/216383/hepatology/serum-keratin-18-promising-aah-biomarker?channel=346
M. Alexander Otto, MDedge News

Jan 29th, 2020 - Serum keratin 18, an epithelial protein released from dying hepatocytes, identifies patients with severe acute alcoholic hepatitis (AAH) at high risk for death, according to an investigation of 173 subjects. Standard biomarker scores – Model for E.

DUR-928 shows promise for alcoholic hepatitis
https://www.mdedge.com/internalmedicine/article/211817/liver-disease/dur-928-shows-promise-alcoholic-hepatitis?channel=226
Will Pass

Nov 8th, 2019 - BOSTON – Treatment with novel agent DUR-928 may be able to reduce mortality rates among patients with severe alcoholic hepatitis, investigators predicted. In an open-label, phase IIa trial, 89% of patients with alcoholic hepatitis responded to tre.

Perceptions of liver transplantation for ALD are evolving
https://www.mdedge.com/gihepnews/article/193024/hepatology/perceptions-liver-transplantation-ald-are-evolving?channel=346
Caleb Rans, MDedge News

Jan 22nd, 2019 - In recent years, the proportion of patients undergoing liver transplantation for alcohol-associated liver disease (ALD) has doubled, suggesting a major shift in attitudes related to transplant indication, according to an analysis of registry data.

Correction: Liver enzymes
https://www.mdedge.com/ccjm/article/175927/correction-liver-enzymes

Oct 1st, 2018 - In the article by Agganis B, Lee D, Sepe T ( Liver enzymes: No trivial elevations, even if asymptomatic. Cleve Clin J Med 2018; 85(8):612–617, doi:10.

Treating Alcoholic Liver Diseases Requires a Full-Spectrum Approach
https://www.medscape.com/viewarticle/899082

Jul 15th, 2018 - Alcoholism: A Global Disorder Consumption of alcohol-containing (ethanol) beverages is a worldwide cause of preventable alcoholic liver disease[1] and can add to the progression of other liver diseases, such as hepatitis C virus infection.[2] Alco...

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Patient Education  7 results see all →