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About 219 results

ALLMedicine™ Fibrolamellar Carcinoma Center

Research & Reviews  109 results

Fibrolamellar carcinoma: Challenging the challenge.
https://doi.org/10.1016/j.ejca.2020.06.035
European Journal of Cancer (Oxford, England : 1990); Lamarca A, Frizziero M et. al.

Aug 9th, 2020 - Fibrolamellar carcinoma (FLC) is a rare and poorly understood malignancy, which seems to be more prevalent in young patients compared with conventional hepatocellular carcinoma (HCC). Performing prospective clinical trials recruiting patients diag...

Molecular profiling and analysis of genetic aberrations aimed at identifying potential ...
https://doi.org/10.1002/cncr.32960
Cancer References; El Dika I, Bowman AS et. al.

Jul 14th, 2020 - Fibrolamellar carcinoma (FLC) is a rare primary liver cancer of young adults. A functional chimeric transcript resulting from the in-frame fusion of the DNAJ homolog, subfamily B, member 1 (DNAJB1), and the catalytic subunit of protein kinase A (P...

Fibrolamellar Carcinoma With Predominantly Pseudoglandular Architecture: A Potential Di...
https://doi.org/10.1177/1066896920933344
International Journal of Surgical Pathology; du Toit M, Aldera AP

Jun 6th, 2020 - Biopsies of liver mass lesions are encountered frequently in general surgical pathology practice. The clinical differential diagnosis is typically hepatocellular carcinoma (HCC) versus metastatic adenocarcinoma. There are a variety of HCC variants...

Fibrolamellar Carcinoma.
https://doi.org/10.1016/j.mayocp.2020.04.024
Mayo Clinic Proceedings; Erickson LA

Jun 5th, 2020 - Fibrolamellar Carcinoma.|2020|Erickson LA,|

A Multicenter Randomized Three-Arm Phase II Study of (1) Everolimus, (2) Estrogen Depri...
https://doi.org/10.1634/theoncologist.2020-0367
The Oncologist References; El Dika I, Mayer RJ et. al.

May 13th, 2020 - FLC is a complex cancer with many implicated oncogenic pathways. Single or dual targeting does not appear to alter the natural history of the cancer, and novel therapeutics are needed. Estrogen deprivation therapy with letrozole and leuprolide, al...

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Clinicaltrials.gov  109 results

Fibrolamellar carcinoma: Challenging the challenge.
https://doi.org/10.1016/j.ejca.2020.06.035
European Journal of Cancer (Oxford, England : 1990); Lamarca A, Frizziero M et. al.

Aug 9th, 2020 - Fibrolamellar carcinoma (FLC) is a rare and poorly understood malignancy, which seems to be more prevalent in young patients compared with conventional hepatocellular carcinoma (HCC). Performing prospective clinical trials recruiting patients diag...

Molecular profiling and analysis of genetic aberrations aimed at identifying potential ...
https://doi.org/10.1002/cncr.32960
Cancer References; El Dika I, Bowman AS et. al.

Jul 14th, 2020 - Fibrolamellar carcinoma (FLC) is a rare primary liver cancer of young adults. A functional chimeric transcript resulting from the in-frame fusion of the DNAJ homolog, subfamily B, member 1 (DNAJB1), and the catalytic subunit of protein kinase A (P...

Fibrolamellar Carcinoma With Predominantly Pseudoglandular Architecture: A Potential Di...
https://doi.org/10.1177/1066896920933344
International Journal of Surgical Pathology; du Toit M, Aldera AP

Jun 6th, 2020 - Biopsies of liver mass lesions are encountered frequently in general surgical pathology practice. The clinical differential diagnosis is typically hepatocellular carcinoma (HCC) versus metastatic adenocarcinoma. There are a variety of HCC variants...

Fibrolamellar Carcinoma.
https://doi.org/10.1016/j.mayocp.2020.04.024
Mayo Clinic Proceedings; Erickson LA

Jun 5th, 2020 - Fibrolamellar Carcinoma.|2020|Erickson LA,|

A Multicenter Randomized Three-Arm Phase II Study of (1) Everolimus, (2) Estrogen Depri...
https://doi.org/10.1634/theoncologist.2020-0367
The Oncologist References; El Dika I, Mayer RJ et. al.

May 13th, 2020 - FLC is a complex cancer with many implicated oncogenic pathways. Single or dual targeting does not appear to alter the natural history of the cancer, and novel therapeutics are needed. Estrogen deprivation therapy with letrozole and leuprolide, al...

see more →

News  1 results

MicroRNA-375 may be key to fibrolamellar carcinoma
https://www.mdedge.com/gihepnews/article/198920/liver-disease/microrna-375-may-be-key-fibrolamellar-carcinoma?channel=69
Will Pass, MDedge News

Apr 15th, 2019 - Up-regulation of microRNA-375 may be a future therapeutic strategy for patients with fibrolamellar carcinoma (FLC), according to investigators. Analysis of primary FLC tumors showed that microRNA-375 was the most abnormal microRNA, down-regulated.

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