ALLMedicine™ Hepatocellular Adenoma Center

Mar 2nd, 2021 - Beta-catenin-activated hepatocellular adenoma is potentially malignant and warrants careful follow-up and surgical resection. Here, we report a 48-year-old man in whom a 55 mm single liver tumor was incidentally detected in the S1 segment. Contras...

Feb 9th, 2021 - Some hepatocellular adenoma (HCA) subtypes are characterized by different CTNNB1 mutations, leading to different beta-catenin activation levels, hence variable immunostaining patterns of glutamine synthetase (GS) expression, and different risks of...

Jan 22nd, 2021 - Data on surgical outcomes of laparoscopic liver resection (LLR) versus open liver resection (OLR) of benign liver tumour (BLT) are scarce. This study aimed to provide a nationwide overview of postoperative outcomes after LLR and OLR of BLT. This w...

Nov 4th, 2020 - To assess the value of hepatospecific MR contrast agent uptake on hepatobiliary phase (HBP) images to detect marked activation of the β-catenin pathway in hepatocellular adenomas (HCAs). This multicentric retrospective IRB-approved study included ...

Oct 15th, 2020 - Histologic distinction between well differentiated hepatocellular carcinoma (HCC) and benign hepatocellular mass lesions is a known challenge. Existing biomarkers are of limited diagnostic value. Our previous studies observed an enhanced canalicul...

Aug 19th, 2014 - Focal liver lesions (FLL) have been a common reason for consultation faced by gastroenterologists and hepatologists. The increasing and widespread use of imaging studies has led to an increase in detection of incidental FLL. It is important to con...

Mar 2nd, 2021 - Beta-catenin-activated hepatocellular adenoma is potentially malignant and warrants careful follow-up and surgical resection. Here, we report a 48-year-old man in whom a 55 mm single liver tumor was incidentally detected in the S1 segment. Contras...

Feb 9th, 2021 - Some hepatocellular adenoma (HCA) subtypes are characterized by different CTNNB1 mutations, leading to different beta-catenin activation levels, hence variable immunostaining patterns of glutamine synthetase (GS) expression, and different risks of...

Jan 22nd, 2021 - Data on surgical outcomes of laparoscopic liver resection (LLR) versus open liver resection (OLR) of benign liver tumour (BLT) are scarce. This study aimed to provide a nationwide overview of postoperative outcomes after LLR and OLR of BLT. This w...

Nov 4th, 2020 - To assess the value of hepatospecific MR contrast agent uptake on hepatobiliary phase (HBP) images to detect marked activation of the β-catenin pathway in hepatocellular adenomas (HCAs). This multicentric retrospective IRB-approved study included ...

Oct 15th, 2020 - Histologic distinction between well differentiated hepatocellular carcinoma (HCC) and benign hepatocellular mass lesions is a known challenge. Existing biomarkers are of limited diagnostic value. Our previous studies observed an enhanced canalicul...

Apr 17th, 2012 - Hepatocellular Adenoma and Focal Nodular Hyperplasia: Value of Gadoxetic Acid-Enhanced MR Imaging in Differential Diagnosis Grazioli L, Bondioni MP, Haradome H, et al Radiology. 2012;262:520-529 Summary The goal of this project was to retrospectiv...

Epidemiology and Etiologic Associations Hepatocellular adenoma has an incidence of 1–1.3 million cases per year in North America and Europe.[12] Several studies have consistently linked the occurrence of HAs to oral contraceptive pill (OCP) use.[1...

Abstract and Introduction Introduction Hepatocellular adenoma (HA) is a relatively uncommon benign liver neoplasm that is typically seen in obese women of childbearing age who are on long-term oral contraceptives.[1] It is also reported to occur i...

Clinical Presentation The majority of HAs are clinically occult and are incidentally detected on imaging. The risk factors for hemorrhage are size >5 cm, a subcapsular location and longstanding OCP use.[10,18,19] HCA associated with hemorrhage may...