About 1,765 results

ALLMedicine™ Primary Biliary Cirrhosis Center

Research & Reviews  590 results

Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome in a patient with parox...
The Journal of International Medical Research; Chen L, Shi X et. al.

May 18th, 2021 - Primary biliary cirrhosis (PBC)-autoimmune hepatitis (AIH) overlap syndrome is frequently associated with extrahepatic autoimmune disorders. Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disease that is characterized by complement-media...

Transcriptional regulator BOB.1: Molecular mechanisms and emerging role in chronic infl...
Autoimmunity Reviews; Yeremenko N, Danger R et. al.

Apr 17th, 2021 - Lymphocytes constitute an essential and potent effector compartment of the immune system. Therefore, their development and functions must be strictly regulated to avoid inappropriate immune responses, such as autoimmune reactions. Several lines of...

Partitioned glioma heritability shows subtype-specific enrichment in immune cells.
Neuro-oncology Ostrom QT, Edelson J et. al.

Mar 20th, 2021 - Epidemiological studies of adult glioma have identified genetic syndromes and 25 heritable risk loci that modify individual risk for glioma, as well increased risk in association with exposure to ionizing radiation and decreased risk in associatio...

Naltrexone for cholestatic itch: a systematic review.
BMJ Supportive & Palliative Care; Murray-Brown FL

Mar 11th, 2021 - Cholestatic itch is caused by intrahepatic liver diseases, such as primary biliary cirrhosis and extrahepatic obstruction of the biliary tree, often caused by tumours. The pathophysiology of cholestatic itch is complex and no single treatment has ...

Disease-specific waitlist outcomes in liver transplantation - a retrospective study.
Transplant International : Official Journal of the Europe... Nagai S, Safwan M et. al.

Jan 10th, 2021 - This study aimed to evaluate possible discrepancies in waitlist outcomes between liver diseases, including alcohol-related liver disease (ALD), nonalcoholic steatohepatitis (NASH), hepatitis C virus infection (HCV), primary biliary cirrhosis (PBC)...

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Guidelines  1 results

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment an...
Gut Hirschfield GM, Dyson JK et. al.

Mar 29th, 2018 - Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in an en...

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Drugs  24 results see all →

Clinicaltrials.gov  27 results

Evaluation of Patients With Liver Disease

Feb 27th, 2020 - This is a general clinical research protocol to allow for evaluation, investigation and long-term follow up of patients who have an acute or chronic liver disease. The protocol is designed to study the natural history and pathogenesis of various l...

Clinical Trial on the Effect of the Sublimated Mare Milk Supplement on Primary Biliary Cholangitis

Feb 24th, 2020 - Primary biliary cholangitis, formerly known as primary biliary cirrhosis, is a rare chronic disease that primarily affects women. Primary biliary cholangitis often progresses to the terminal stage of liver cirrhosis with its inherent complications...

Examination of the Metabolic Effects of Direct Bile Salt Delivery to the Ileum in Humans

Feb 6th, 2020 - Ursodeoxycholic acid (UDCA) is currently FDA-approved for the treatment of gallstone dissolution and primary biliary cirrhosis. Other than these two diseases, exploratory research - both preclinical and clinical - has demonstrated other beneficial...

The Assesment of MMP-1 Genotypes Polymorphism as a Risk Factor for HCC in Chronic HCV Patients With LC

Oct 28th, 2018 - This study is a case-control observational study to be done at Clinical pathology department, Assiut University hospital, Assiut University, Egypt. The control population comprised 20 healthy individuals with no liver infection. Patients will be s...

Use of Fenofibrate for Primary Biliary Cirrhosis

Mar 7th, 2018 - This is a multicenter open label pilot study to evaluate the efficacy of fenofibrate in 20 patients with PBC treated for 1 year. A randomized design would not be feasible at this stage of the research. Two sites are enrolling patients: University ...

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News  56 results

Scleromyxedema in a Patient With Thyroid Disease: An Atypical Case or a Case for Revised Criteria?

Jan 17th, 2020 - Comment Classification Lichen myxedematosus is differentiated into localized and generalized forms. The former is limited to the skin and lacks monoclonal gammopathy.

Primary Biliary Cholangitis: The Latest Data on an Evolving Disorder

Jan 3rd, 2019 - What we once called "primary biliary cirrhosis" is now termed "primary biliary cholangitis" (PBC).[1] The original name never quite fit, given that patients with PBC usually do not have cirrhosis at the time of clinical presentation.[2] "Chronic n...

Women, older patients at greater risk of more aggressive PBC
Bianca Nogrady, MDedge News

Sep 13th, 2018 - A large, real-world study of primary biliary cholangitis has revealed that patients who are female, older, or have other autoimmune diseases are likely to have a more progressed and aggressive disease profile. In the Journal of Clinical Gastroente.

Clinical trial: Understanding the Genetic Predisposition to the Development of Primary Biliary Cirrhosis
Lucas Franki, MDedge News

Sep 20th, 2017 - Understanding the Genetic Predisposition to the Development of Primary Biliary Cirrhosis is an observational study recruiting people with a history of PBC and their family members. The trial will investigate whether or not there is a genetic facto.

Hep C Experts Condemn Cochrane Review Dissing Direct Antivirals

Jun 27th, 2017 - When the pharmaceutical company Gilead launched its hepatitis C drug sofosbuvir (Sovaldi) in 2013, it justified the $1,000 per-pill price by pointing to ironclad data on its life-saving potential. Chiefly, clinical trials clearly demonstrated the ...

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Patient Education  8 results see all →