ALLMedicine™ Alcoholic Hepatitis Center

Nov 23rd, 2022 - Higher prevalence of alcohol-related gastrointestinal (GI) and liver diseases (ARGLDs) were anecdotally reported during the COVID-19 pandemic, but little published evidence exists. A healthcare system audit of inpatient GI consults was performed d...

Nov 22nd, 2022 - Liver transplantation (LT) for severe alcohol-associated hepatitis (AH) remains controversial due to perceived increased recidivism risk after LT because of a lack of protracted abstinence before LT. Data on risk stratification for alcohol relapse...

Nov 19th, 2022 - Emergency admissions in England for alcohol-related liver disease (ArLD) have increased steadily for decades. Statistics based on administrative data typically focus on the ArLD-specific code as the primary diagnosis and are therefore at risk of e...

Nov 18th, 2022 - Acute-on-chronic liver failure (ACLF) is a complex clinical syndrome, and patients often have high short-term mortality. It occurs with intense systemic inflammation, often accompanied by a proinflammatory event (such as infection or alcoholic hep...

Nov 10th, 2022 - Alcohol consumption has been shown to disrupt hepatic lipid homeostasis. Long-chain acyl-CoA synthetase 1 (ACSL1) critically regulates hepatic fatty acid metabolism and lipid homeostasis by channeling fatty acids to lipid metabolic pathways. Howev...

Jan 18th, 2018 - Alcoholic liver disease (ALD) comprises a clinical-histologic spectrum including fatty liver, alcoholic hepatitis (AH), and cirrhosis with its complications. Most patients are diagnosed at advanced stages and data on the prevalence and profile of ...

Apr 17th, 2017 - The purpose of this clinical practice update is to review diagnostic criteria for severe acute alcoholic hepatitis and to determine the current best practices for this life-threatening condition. The best practices in this review are based on clin...

Feb 28th, 2016 - Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia.|2016|Crabb DW,Bataller R,Chalasani NP,Kamath PS,Lucey M,|classification,standards,...

Sep 30th, 2022 - This is a randomized, double-blind, placebo-controlled, phase 2b clinical Trial evaluating Safety and Efficacy of DUR-928 (an experimental medication) in Patients with Alcoholic Hepatitis (AH).

Sep 16th, 2022 - This multicenter, randomized, double blinded, placebo-controlled clinical trial is focused on novel treatments for severe alcoholic hepatitis (AH), a life-threatening stage of alcoholic liver injury that has a short-term mortality rate much higher...

Sep 9th, 2022 - In the United States, alcoholic liver disease (ALD) is the second most common indication for liver transplant (LT). Traditionally, ALD patients have been required to complete a six-month mandatory period of alcohol abstinence before LT. More recen...

Aug 12th, 2022 - Primary biliary cholangitis (PBC, previously called 'primary biliary cirrhosis') is an autoimmune cholestatic liver disease characterized by destruction of intrahepatic bile ducts and progression to liver fibrosis and cirrhosis. In the pre-cirrhot...

Aug 8th, 2022 - Severe alcoholic hepatitis is defined as alcoholic hepatitis patients having discriminant function (DF) score over 32 or accompanying hepatic encephalopathy. These patients have shown poor prognosis of 28 day mortality as 30 to 50% without treatme...

Nov 9th, 2022 - WASHINGTON — Adding granulocyte-colony stimulating factor (G-CSF) to steroid therapy can improve 90-day survival for patients with severe alcoholic hepatitis (SAH), researchers from India reported. Among patients with SAH, the combination of G-CSF...

Jul 29th, 2022 - Past decompensation in alcohol-associated hepatitis may be linked with worse survival following liver transplantation, but it's not all bad news, according to a retrospective study. Traditionally, patients with alcoholic liver disease were asked t...

Jun 1st, 2022 - Guidelines for the management of alcohol-related liver disease were published in April 2022 by the French Association for the Study of the Liver (AFEF) in Liver International.[1] Use the AUDIT-C questionnaire in general practice and specialist con...

May 24th, 2022 - SAN DIEGO — Treating people with alcoholic hepatitis for alcohol abuse may reduce their risk of hospital readmission, researchers reported. In a retrospective analysis of nationwide data, 7.83% of those patients who received psychotherapy, counsel...

May 22nd, 2022 - SAN DIEGO – Treating people with alcoholic hepatitis for alcohol abuse may reduce their risk of hospital readmission, researchers reported. In a retrospective analysis of nationwide data, 7.