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About 2,215 results

ALLMedicine™ Alcoholic Hepatitis Center

Research & Reviews  670 results

Integrated Approaches for Identifying Molecular Targets in Liver Disease
https://clinicaltrials.gov/ct2/show/NCT03915002

Jun 30th, 2022 - In 2015, chronic liver diseases were responsible for approximately 2% of worldwide mortality and in 2016 cirrhosis and chronic liver diseases accounted for 531.1 age- standardized, Disability Adjusted Life Years (DALY's) /100,000 habitants.(1, 2) ...

The clinical implication of psychiatric illnesses in patients with alcoholic liver dise...
https://doi.org/10.1080/17474124.2022.2090337
Expert Review of Gastroenterology & Hepatology; Lee DU, Chou H et. al.

Jun 17th, 2022 - In this study, we evaluate the clinical impact of psychiatric illnesses (PI) on the hospital outcomes of patients admitted with alcoholic liver disease (ALD). From the National Inpatient Sample from 2012-2017, patients with alcoholic cirrhosis or ...

Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and m...
https://doi.org/10.1002/hep.32604
Hepatology (Baltimore, Md.); Ma X, Chen A et. al.

Jun 15th, 2022 - Increased megamitochondria formation and impaired mitophagy in hepatocytes have been linked to the pathogenesis of alcohol-associated liver disease (ALD). This study aims to determine the mechanisms by which alcohol consumption increases megamitoc...

A Phase 2b Study in Subjects With Alcoholic Hepatitis to Evaluate Safety and Efficacy of DUR-928 Treatment
https://clinicaltrials.gov/ct2/show/NCT04563026

Jun 14th, 2022 - This is a randomized, double-blind, placebo-controlled, phase 2b clinical Trial evaluating Safety and Efficacy of DUR-928 (an experimental medication) in Patients with Alcoholic Hepatitis (AH).

Safety Evaluation of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis
https://clinicaltrials.gov/ct2/show/NCT05006430

Jun 6th, 2022 - Background: Alcoholic hepatitis (AH) is a major public health problem in the United States, caused by chronic alcohol consumption of more than 40-60 g/day. Approximately 5 million Americans are diagnosed with AH, contributing to 5% of US annual mo...

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Guidelines  3 results

ACG Clinical Guideline: Alcoholic Liver Disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524956
The American Journal of Gastroenterology; Singal AK, Bataller R et. al.

Jan 18th, 2018 - Alcoholic liver disease (ALD) comprises a clinical-histologic spectrum including fatty liver, alcoholic hepatitis (AH), and cirrhosis with its complications. Most patients are diagnosed at advanced stages and data on the prevalence and profile of ...

Medical Management of Severe Alcoholic Hepatitis: Expert Review from the Clinical Practice Updates Committee of the AGA Institute
https://www.cghjournal.org/article/S1542-3565(16)30798-4/fulltext?code=yjcgh-site

Apr 17th, 2017 - The purpose of this clinical practice update is to review diagnostic criteria for severe acute alcoholic hepatitis and to determine the current best practices for this life-threatening condition. The best practices in this review are based on clin...

Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alco...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287362
Gastroenterology Crabb DW, Bataller R et. al.

Feb 28th, 2016 - Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia.|2016|Crabb DW,Bataller R,Chalasani NP,Kamath PS,Lucey M,|classification,standards,...

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Clinicaltrials.gov  113 results

Integrated Approaches for Identifying Molecular Targets in Liver Disease
https://clinicaltrials.gov/ct2/show/NCT03915002

Jun 30th, 2022 - In 2015, chronic liver diseases were responsible for approximately 2% of worldwide mortality and in 2016 cirrhosis and chronic liver diseases accounted for 531.1 age- standardized, Disability Adjusted Life Years (DALY's) /100,000 habitants.(1, 2) ...

A Phase 2b Study in Subjects With Alcoholic Hepatitis to Evaluate Safety and Efficacy of DUR-928 Treatment
https://clinicaltrials.gov/ct2/show/NCT04563026

Jun 14th, 2022 - This is a randomized, double-blind, placebo-controlled, phase 2b clinical Trial evaluating Safety and Efficacy of DUR-928 (an experimental medication) in Patients with Alcoholic Hepatitis (AH).

Safety Evaluation of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis
https://clinicaltrials.gov/ct2/show/NCT05006430

Jun 6th, 2022 - Background: Alcoholic hepatitis (AH) is a major public health problem in the United States, caused by chronic alcohol consumption of more than 40-60 g/day. Approximately 5 million Americans are diagnosed with AH, contributing to 5% of US annual mo...

Study of Genetic Determinants in Alcoholic Hepatitis and Establishment of a Multicenter Prospective Cohort of Patients With Alcoholic Liver Disease
https://clinicaltrials.gov/ct2/show/NCT04106518

May 18th, 2022 - Alcoholic hepatitis carries a risk of high mortality at short term, especially in its severe form. Its diagnosis is confirmed by liver biopsy. The prevalence of alcoholic hepatitis, severe or not severe, is poorly known and prospective data are ne...

HA35 Moderate Alcoholic Hepatitis (AH) Study
https://clinicaltrials.gov/ct2/show/NCT05018481

May 9th, 2022 - Written informed consent will be obtained during the baseline visit (day 1). Patients will given a physical exam and a blood test will be obtained if not in their medical chart. The subjects who meet the criteria after the screening visit will hav...

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News  95 results

Alcohol-related Liver Disease Clinical Practice Guidelines (AFEF, 2022)
https://www.medscape.com/viewarticle/974654

Jun 1st, 2022 - Guidelines for the management of alcohol-related liver disease were published in April 2022 by the French Association for the Study of the Liver (AFEF) in Liver International.[1] Use the AUDIT-C questionnaire in general practice and specialist con...

Treatment for Alcohol Abuse Reduces Hepatitis Readmission
https://www.medscape.com/viewarticle/974503

May 24th, 2022 - SAN DIEGO — Treating people with alcoholic hepatitis for alcohol abuse may reduce their risk of hospital readmission, researchers reported. In a retrospective analysis of nationwide data, 7.83% of those patients who received psychotherapy, counsel...

Treatment for alcohol abuse reduces hepatitis readmission
https://www.mdedge.com/internalmedicine/article/254812/hepatology/treatment-alcohol-abuse-reduces-hepatitis-readmission
Laird Harrison

May 22nd, 2022 - SAN DIEGO – Treating people with alcoholic hepatitis for alcohol abuse may reduce their risk of hospital readmission, researchers reported. In a retrospective analysis of nationwide data, 7.

Trending Clinical Topic: Hepatitis
https://www.medscape.com/viewarticle/971430

May 6th, 2022 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook.  A worldwide ...

Celebrating our colleagues
https://www.mdedge.com/gihepnews/article/253364/mixed-topics/celebrating-our-colleagues

Apr 1st, 2022 - In this month’s issue of GI & Hepatology News, we celebrate the recently named recipients of this year’s AGA Recognition Prizes, several of whom I am privileged to work with on a daily basis. We also welcome the newest members of AGA’s Governing B.

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Patient Education  5 results see all →