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About 208 results

ALLMedicine™ Fibrolamellar Carcinoma Center

Research & Reviews  66 results

FibroLamellar Carcinoma: an International Registry Study
https://clinicaltrials.gov/ct2/show/NCT05730686

Feb 16th, 2023 - Fibrolamellar Hepatocellular Carcinoma (FLC) is a rare (0.05 per 100,000) subtype of primary liver cancer which predominantly affects younger patients, median age of diagnosis 22-23 years. In patients with advanced stage disease the prognosis is p...

Fibrolamellar carcinoma transcriptomic-based treatment prediction: complete response af...
https://doi.org/10.1136/jitc-2022-005620
Journal for Immunotherapy of Cancer; Berger R, Dinstag G et. al.

Jan 6th, 2023 - Fibrolamellar carcinoma (FLC) is a rare cancer of the liver that most commonly affects children and young adults. There is no clear standard of care for the disease, whose response to treatment seems to be very different from that of hepatocellula...

Fibrolamellar Carcinoma
https://emedicine.medscape.com/article/278354-overview

Oct 17th, 2022 - Practice Essentials Fibrolamellar carcinoma (FLC) is a primary liver cancer that occurs in adolescents and young adults without underlying liver disease. Although FLC was historically considered to be a histologic variant of hepatocellular carcino...

Fibrolamellar Carcinoma
http://emedicine.medscape.com/article/278354-overview

Oct 17th, 2022 - Practice Essentials Fibrolamellar carcinoma (FLC) is a primary liver cancer that occurs in adolescents and young adults without underlying liver disease. Although FLC was historically considered to be a histologic variant of hepatocellular carcino...

Fibrolamellar Carcinoma
https://emedicine.medscape.com/article/278354-print

Oct 17th, 2022 - Practice Essentials Fibrolamellar carcinoma (FLC) is a primary liver cancer that occurs in adolescents and young adults without underlying liver disease. Although FLC was historically considered to be a histologic variant of hepatocellular carcino...

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Clinicaltrials.gov  5 results

FibroLamellar Carcinoma: an International Registry Study
https://clinicaltrials.gov/ct2/show/NCT05730686

Feb 16th, 2023 - Fibrolamellar Hepatocellular Carcinoma (FLC) is a rare (0.05 per 100,000) subtype of primary liver cancer which predominantly affects younger patients, median age of diagnosis 22-23 years. In patients with advanced stage disease the prognosis is p...

Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer
https://clinicaltrials.gov/ct2/show/NCT03860272

Sep 16th, 2022 - This Phase 1 study will enroll up to approximately 195 evaluable adult participants with refractory cancer (solid tumors) regardless of diagnosis. The study will consist of a 3+3 dose escalation. Different dose levels of botensilimab, both monothe...

A Multi-center, Open-label Study of Oral ENMD-2076 for the Treatment of Patients With Advanced Fibrolamellar Carcinoma
https://clinicaltrials.gov/ct2/show/NCT02234986

Sep 6th, 2018 - Primary Objective: • To determine the 6-month progression free survival (PFS6) rate when patients with advanced fibrolamellar carcinoma (FLC) are treated with daily oral ENMD 2076 Secondary Objectives: To evaluate the overall response rate using R...

Study of Sunitinib in Patients With Advanced/Inoperable Fibrolamellar Carcinoma
https://clinicaltrials.gov/ct2/show/NCT01215565

Mar 13th, 2014 - Fibrolamellar hepatocellular carcinoma is variant rare of hepatocellular carcinoma witch distinct clinical, histological and prognostic features from conventional hepatocellular carcinoma. This entity typically occurs in young adults with no under...

Biomarkers in Stored Tumor Samples From Younger Patients With Liver Cancer
https://clinicaltrials.gov/ct2/show/NCT00899002

Apr 10th, 2013 - OBJECTIVES: To characterize, at a molecular level, archived samples of tissue from young patients with fibrolamellar carcinoma and hepatocellular carcinoma in non-cirrhotic livers matched for age and sex. To perform genomic analysis on these tissu...

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News  12 results

Pediatric HCC: Histologic subtypes demonstrate distinct clinical patterns
https://www.mdedge.com/gihepnews/article/255714/hepatocellular-carcinoma/pediatric-hcc-histologic-subtypes-demonstrate

Jun 23rd, 2022 - Key clinical point: The pediatric hepatocellular carcinoma (HCC) subtypes fibrolamellar carcinoma (FLC) and conventional HCC (cHCC) can be considered nonequivalent entities because they show different anatomic patterns and outcomes together with t.

Yarchoan Talks Research Directions in Fibrolamellar Carcinoma
https://www.onclive.com/view/yarchoan-talks-research-directions-in-fibrolamellar-carcinoma

Nov 4th, 2021 - Welcome to OncLive On Air®! I’m your host today, Jason Harris. OncLive On Air® is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and pr...

Dr. Yarchoan on Unique Characteristics of Fibrolamellar Carcinoma
https://www.onclive.com/view/dr-yarchoan-on-unique-characteristics-of-fibrolamellar-carcinoma

Oct 22nd, 2021 - Mark Yarchoan, MD, assistant professor of oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medicine, discusses unique characteristics of fibrolamellar carcinoma (FC). FC is a distinct type of liver cancer, Yarchoan says. Unlik...

Lessons Learned May Hold the Key for Improving Outcomes in Fibrolamellar Carcinoma
https://www.onclive.com/view/lessons-learned-may-hold-the-key-for-improving-outcomes-in-fibrolamellar-carcinoma

Oct 21st, 2021 - Fibrolamellar carcinoma is an extremely rare form of liver cancer that affects approximately 1 in 5 million Americans.1 However, because the disease appears so infrequently, it may be underdiagnosed, said Mark Yarchoan, MD. He added that, with an ...

Abou-Alfa Highlights HCC Advances, Unmet Needs in Other GI Cancers
https://www.onclive.com/view/aboualfa-highlights-hcc-advances-unmet-needs-in-other-gi-cancers

Oct 6th, 2021 - Ghassan Abou-Alfa, MD While the hepatocellular carcinoma (HCC) field shifted in 2018 with the addition of newly available treatment options, more pivotal research is on the way, said Ghassan K. Abou-Alfa, MD. For a 10-year span, there was only 1...

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