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About 30,458 results

ALLMedicine™ Liver Transplantation Center

Research & Reviews  11,246 results

Graft fibrosis over 10 to 15 years in pediatric liver transplant recipients: Multi-cent...
https://doi.org/10.1002/lt.26409
Liver Transplantation : Official Publication of the Ameri... Perito ER, Persyn E et. al.

Jan 15th, 2022 - Previous single-center, cross-sectional studies have reported a steep increase in the prevalence and severity of fibrosis through 10-15 years after pediatric liver transplantation. We report a multi-center study of paired surveillance biopsies in ...

Development of the AI-Cirrhosis-ECG (ACE) Score: An electrocardiogram-based deep learni...
https://doi.org/10.14309/ajg.0000000000001617
The American Journal of Gastroenterology; Ahn JC, Attia ZI et. al.

Jan 15th, 2022 - Cirrhosis is associated with cardiac dysfunction and distinct ECG abnormalities. This study aimed to develop a proof-of-concept deep learning-based artificial intelligence (AI) model that could detect cirrhosis-related signals on ECG and generate ...

Long-term outcomes in pediatric patients who underwent living donor liver transplantati...
https://doi.org/10.1016/j.surg.2021.11.027
Surgery Sanada Y, Sakuma Y et. al.

Jan 15th, 2022 - There is no consensus about long-term outcomes in patients with biliary atresia. We retrospectively reviewed the long-term outcomes in pediatric patients who underwent living donor liver transplantation for biliary atresia. Between May 2001 and De...

Biliary atresia combined Wilson disease identified by whole exome sequencing in Vietnam...
https://doi.org/10.1097/MD.0000000000028547
Medicine Hoa NPA, Lien NTK et. al.

Jan 15th, 2022 - Hepatobiliary diseases such as biliary atresia (BA), Wilson disease, and progressive familial intrahepatic cholestasis are common causes of morbidity and mortality in young children. Affected patients progress rapidly to end-stage cirrhosis and re...

Mechanisms of liver injury in high fat sugar diet fed mice that lack hepatocyte X-box b...
https://doi.org/10.1371/journal.pone.0261789
PloS One; Liu X, Taylor SA et. al.

Jan 15th, 2022 - Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of liver diseases in the United States and can progress to cirrhosis, end-stage liver disease and need for liver transplantation. There are limited therapies for NAFLD, in p...

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Guidelines  23 results

Non-invasive diagnosis and follow-up in liver transplantation.
https://doi.org/10.1016/j.clinre.2021.101774
Clinics and Research in Hepatology and Gastroenterology; Dumortier J, Besch C et. al.

Aug 1st, 2021 - The field of liver transplantation directly or indirectly embodies all liver diseases, in addition to specific ones related to organ rejection (cellular and humoral). The recommended non-invasive methods for determining the indication for liver tr...

Donor Warm Ischemia Time in DCD Liver Transplantation-Working Group Report From the ILT...
https://doi.org/10.1097/TP.0000000000003819
Transplantation Kalisvaart M, Croome KP et. al.

May 29th, 2021 - Donation after circulatory death (DCD) grafts are commonly used in liver transplantation. Attributable to the additional ischemic event during the donor warm ischemia time (DWIT), DCD grafts carry an increased risk for severe ischemia/reperfusion ...

Design, Analysis, and Pitfalls of Clinical Trials Using Ex Situ Liver Machine Perfusion...
https://doi.org/10.1097/TP.0000000000003573 10.1002/hep.31686 10.1016/j.jhep.2020.09.015
Transplantation Martins PN, Rizzari MD et. al.

Mar 25th, 2021 - Recent trials in liver machine perfusion (MP) have revealed unique challenges beyond those seen in most clinical studies. Correct trial design and interpretation of data are essential to avoid drawing conclusions that may compromise patient safety...

Regulations and Procurement Surgery in DCD Liver Transplantation: Expert Consensus Guid...
https://doi.org/10.1097/TP.0000000000003729
Transplantation Hessheimer AJ, Polak W et. al.

Mar 7th, 2021 - Donation after circulatory death (DCD) donors are an increasingly more common source of livers for transplantation in many parts of the world. Events that occur during DCD liver recovery have a significant impact on the success of subsequent trans...

AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achie...
https://doi.org/10.1053/j.gastro.2020.11.051
Gastroenterology Younossi ZM, Corey KE et. al.

Dec 12th, 2020 - Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease, with global public health impact affecting more than 25% of the global population. NAFLD is associated with significant morbidity and mortality from cirrhosis, h...

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Drugs  17 results see all →

Clinicaltrials.gov  378 results

Electrical Impedance Tomography in Fatty Liver Detection
https://clinicaltrials.gov/ct2/show/NCT05189990

Jan 13th, 2022 - Fatty liver disease is a condition where the hepatocytes (liver cells) contain more than 5% fat. This condition is becoming increasingly common due to unhealthy food habits and sedentary lifestyle. Since NAFLD is a silent disease with symptoms ari...

Bridge to Orthotopic Liver Transplantation (OLT) - Surefire Precision vs Endhole Embolization With DEBTACE
https://clinicaltrials.gov/ct2/show/NCT03170869

Jan 12th, 2022 - This is a single institution prospective clinical trial with historical matched controls. This protocol standardizes DEB-TACE delivery with the Surefire Precision Infusion System. This protocol does not change patient therapy. All patient safety m...

Longitudinal Assessment of Muscle Health in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma
https://clinicaltrials.gov/ct2/show/NCT05184283

Jan 11th, 2022 - The combination of hepatocellular carcinoma and chronic liver disease represents a dual impact on overall metabolism. The major risk factors for chronic liver disease related-hepatocellular carcinoma (HCC) include nonalcoholic fatty liver disease ...

Mean Systemic Filling Pressure Trends in Liver Transplant Recipients
https://clinicaltrials.gov/ct2/show/NCT04462874

Jan 10th, 2022 - Patients with end stage liver disease undergoing liver transplantation have varying degrees of intraoperative haemodynamic unstability during various phases of transplantation. It is difficult to determine the cause for hemodynamic instability in ...

Dexmedetomidine and Liver Transplantation
https://clinicaltrials.gov/ct2/show/NCT03770130

Jan 6th, 2022 - 1.1. Background 1.1.1. Perioperative ischaemia/reperfusion (I/R) injury during liver transplantation is strongly associated with early allograft dysfunction, graft loss, and mortality. 1.1.2. Hepatic I/R injury also causes remote damage to other o...

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News  517 results

Utilization of AFP to predict HCC recurrence after liver transplantation in waitlisted patients
https://www.mdedge.com/fedprac/article/250481/hepatocellular-carcinoma/utilization-afp-predict-hcc-recurrence-after-liver

Jan 6th, 2022 - Key clinical point : Alpha-fetoprotein (AFP) levels during liver transplantation (LT) and their modulation while on the waitlist are predictors of hepatocellular carcinoma (HCC) recurrence after LT in patients meeting the Milan criteria. Main find.

Skyrocketing Demand for Liver Transplant Among Older Americans
https://www.medscape.com/viewarticle/962947

Nov 16th, 2021 - NEW YORK (Reuters Health) - Over the past two decades, the need for liver transplant (LT) in older adults has risen sharply, due to rising rates of nonalcoholic steatohepatitis (NASH), and the outcomes of LT in these patients has been improving, a...

Alcohol-Related Liver Disease Severity Increased During COVID-19
https://www.medscape.com/viewarticle/962789

Nov 11th, 2021 - Over the course of the COVID-19 pandemic, alcohol-related liver disease has increased in severity, a finding that is likely related to higher consumption of alcohol and reduced care. The difference was notable in higher Model for End-Stage Liver D...

India's COVID Spike and Plummet. What Have We Learned?
https://www.medpagetoday.com/infectiousdisease/covid19/95354

Oct 29th, 2021 - The severity of India's second COVID-19 wave took the world by surprise. Cases skyrocketed, at one point accounting for roughly half of the total infections reported globally. Then, almost as quickly, the numbers plunged. MedPage Today spoke with ...

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Patient Education  2 results see all →