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About 1,798 results

ALLMedicine™ Primary Biliary Cirrhosis Center

Research & Reviews  617 results

Evaluation of Patients With Liver Disease
https://clinicaltrials.gov/ct2/show/NCT00001971

Nov 18th, 2021 - This is a general clinical research protocol to allow for evaluation, investigation and long-term follow up of patients who have an acute or chronic liver disease. The protocol is designed to study the natural history and pathogenesis of various l...

Primary biliary cirrhosis associated with myasthenia gravis after postpartum: a case re...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502364
Journal of Medical Case Reports; Zhang L, Ding D et. al.

Oct 11th, 2021 - Autoimmune diseases refers to a class of diseases involving abnormal immune response of human body and tissue damage caused by the dysregulation of autoimmune balance or destruction of immune tolerance. Recent research has revealed that the occurr...

Identification of causal metabolites related to multiple autoimmune diseases.
https://doi.org/10.1093/hmg/ddab273
Human Molecular Genetics; Yu XH, Cao RR et. al.

Sep 16th, 2021 - Observational studies provide evidence that metabolites may be involved in the development of autoimmune diseases (ADs), but whether it is causal is still unknown. Based on the large-scale GWAS summary statistics, two-sample Mendelian randomizatio...

Glycan biomarkers of autoimmunity and bile acid-associated alterations of the human gly...
https://doi.org/10.1016/j.clim.2021.108825
Clinical Immunology (Orlando, Fla.); Maverakis E, Merleev AA et. al.

Aug 18th, 2021 - We have recently introduced multiple reaction monitoring (MRM) mass spectrometry as a novel tool for glycan biomarker research and discovery. Herein, we employ this technique to characterize the site-specific glycan alterations associated with pri...

Lipid-Lowering Agents
https://emedicine.medscape.com/article/2172172-overview

Jul 13th, 2021 - Lipid-Lowering Agents HMG-CoA reductase inhibitors (statins) These agents inhibit the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase. [1] Note the following: Low-density lipoprotein (LDL) reduction of ...

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Guidelines  1 results

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment an...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109281
Gut Hirschfield GM, Dyson JK et. al.

Mar 30th, 2018 - Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in an en...

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Drugs  22 results see all →

Clinicaltrials.gov  18 results

Evaluation of Patients With Liver Disease
https://clinicaltrials.gov/ct2/show/NCT00001971

Nov 18th, 2021 - This is a general clinical research protocol to allow for evaluation, investigation and long-term follow up of patients who have an acute or chronic liver disease. The protocol is designed to study the natural history and pathogenesis of various l...

sCD163 in PBC Patients - Assessment of Disease Severity and Prognosis
https://clinicaltrials.gov/ct2/show/NCT02924701

Apr 26th, 2021 - Primary biliary cholangitis (PBC, previously called 'primary biliary cirrhosis') is an autoimmune cholestatic liver disease characterized by destruction of intrahepatic bile ducts and progression to liver fibrosis and cirrhosis. In the pre-cirrhot...

sCD163 in PBC Patients - Assessment of Treatment Response
https://clinicaltrials.gov/ct2/show/NCT02931513

Apr 26th, 2021 - Primary biliary cholangitis (PBC, previously called 'primary biliary cirrhosis') is an autoimmune cholestatic liver disease characterized by destruction of intrahepatic bile ducts and progression to liver fibrosis and cirrhosis. In the pre-cirrhot...

Biobank for Cholestatic Liver Diseases.
https://clinicaltrials.gov/ct2/show/NCT03445585

Feb 23rd, 2021 - This study is a biobank of specimens and clinical data for use in current and future research to better understand the cholestatic liver diseases primary biliary cirrhosis/cholangitis (PBC) and primary sclerosing cholangitis (PSC). Blood, saliva, ...

Hepatocellular Carcinoma in HIV-infected Individuals in Asian Population
https://clinicaltrials.gov/ct2/show/NCT03702998

Jan 27th, 2021 - The incidence of hepatocellular carcinoma (HCC) is increasing over time among the HIV-infected population, and is an increasingly important cause of morbidity and mortality in HIV-infected individuals. Despite effective treatment for HBV and HCV i...

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News  59 results

Fast Five Quiz: Fingernail and Toenail Conditions
https://reference.medscape.com/viewarticle/924830_5

Feb 7th, 2020 - Clubbing can be idiopathic or secondary to many underlying pathologies in various organ systems. Causes of idiopathic or primary clubbing include pachydermoperiostosis, familial clubbing, and hypertrophic osteoarthropathy. Causes of secondary club...

Scleromyxedema in a Patient With Thyroid Disease: An Atypical Case or a Case for Revised Criteria?
https://www.mdedge.com/dermatology/article/215717/mixed-topics/scleromyxedema-patient-thyroid-disease-atypical-case-or-case/page/0/1?channel=27442

Jan 17th, 2020 - Comment Classification Lichen myxedematosus is differentiated into localized and generalized forms. The former is limited to the skin and lacks monoclonal gammopathy.

Primary Biliary Cholangitis: The Latest Data on an Evolving Disorder
https://www.medscape.com/viewarticle/907043

Jan 4th, 2019 - What we once called "primary biliary cirrhosis" is now termed "primary biliary cholangitis" (PBC).[1] The original name never quite fit, given that patients with PBC usually do not have cirrhosis at the time of clinical presentation.[2] "Chronic n...

Women, older patients at greater risk of more aggressive PBC
https://www.mdedge.com/gihepnews/article/174769/hepatology/women-older-patients-greater-risk-more-aggressive-pbc
Bianca Nogrady, MDedge News

Sep 13th, 2018 - A large, real-world study of primary biliary cholangitis has revealed that patients who are female, older, or have other autoimmune diseases are likely to have a more progressed and aggressive disease profile. In the Journal of Clinical Gastroente.

Clinical trial: Understanding the Genetic Predisposition to the Development of Primary Biliary Cirrhosis
https://www.mdedge.com/gihepnews/article/147510/hepatology/clinical-trial-understanding-genetic-predisposition-development
Lucas Franki, MDedge News

Sep 20th, 2017 - Understanding the Genetic Predisposition to the Development of Primary Biliary Cirrhosis is an observational study recruiting people with a history of PBC and their family members. The trial will investigate whether or not there is a genetic facto.

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Patient Education  2 results see all →