ALLMedicine™ Chronic Pancreatitis Center

Jan 16th, 2022 - Genetic mutations in various pancreatic enzymes or their counteracting proteins have been linked to chronic pancreatitis. In particular, variants in the genes encoding pancreatic lipase (PNLIP) and carboxyl ester lipase (CEL) have been associated ...

Jan 16th, 2022 - Calcium-selective channel TRPV6 (Transient Receptor Potential channel family, Vanilloid subfamily member 6) belongs to the TRP family of cation channels and plays critical roles in transcellular calcium (Ca2+) transport, reuptake of Ca2+ into cell...

Jan 15th, 2022 - BACKGROUND Pancreaticopleural fistula (PPF) is a rare complication of acute and chronic pancreatitis. PPF results from the release of pancreatic enzymes, either from a damaged pancreatic duct or pancreatic pseudocyst. This report is of a 58-year-o...

Jan 11th, 2022 - Total pancreatectomy with islet autotransplantation (TPIAT) is indicated to alleviate debilitating pancreas-related pain and mitigate diabetes in patients with acute recurrent and chronic pancreatitis when medical/endoscopic therapies fail. Our ai...

Jan 6th, 2022 - Acute recurrent pancreatitis (ARP) due to alcohol and/or tobacco abuse is a preventable disease which lowers quality of life and can lead to chronic pancreatitis. The REAPPEAR study aims to investigate whether a combined patient education and cess...

Nov 2nd, 2020 - EUS remains a primary diagnostic tool for the evaluation of pancreaticobiliary disease. Although EUS combined with FNA or biopsy sampling is highly sensitive for the diagnosis of neoplasia within the pancreaticobiliary tract, limitations exist in ...

Aug 15th, 2020 - This paper is part of the international consensus guidelines on chronic pancreatitis, presenting for interventional endoscopy. An international working group with experts on interventional endoscopy evaluated 26 statements generated from evidence ...

Jul 8th, 2020 - Chronic pancreatitis (CP) is a complex inflammatory disease with variable presentations and outcomes. This statement is part of the international consensus guidelines on CP, specifically on the diagnostic role of endoscopic ultrasound (EUS). An in...

Jul 7th, 2020 - Patients with chronic pancreatitis (CP) have an increased risk of pancreatic cancer. We present the international consensus guidelines for surveillance of pancreatic cancer in CP. The international group evaluated 10 statements generated from evid...

May 18th, 2020 - Chronic pancreatitis is a complex multifactorial fibro-inflammatory disease. Consensus guidelines are needed for the histopathological evaluation of non-autoimmune chronic pancreatitis (CP). An international working group with experts on the histo...

Jan 4th, 2022 - The pancreas is a retroperitoneal organ that can cause inflammatory and neoplastic diseases, significantly impacting the quality of life to survival. Acute pancreatitis is one of the most frequent gastrointestinal causes for hospital admission in ...

Jan 3rd, 2022 - Patients suffering from pancreas cancer as well as patients with chronic pancreatitis or requiring pancreas surgery often are in a compromised nutritional status. Nutritional support should therefore be started early during the postoperative cours...

Nov 12th, 2021 - Management of pancreatic disorders imparts a major burden on healthcare costs, estimated at over 3 billion dollars annually. Chronic pancreatitis is characterized by chronic inflammation and progressive scarring, leading to abdominal pain, irrever...

Oct 21st, 2021 - Exocrine pancreatic insufficiency (EPI) is a condition that is caused by the inadequate pancreatic enzymes needed for normal digestion and is commonly associated with a wide range of chronic diseases, including cystic fibrosis (CF), chronic pancre...

Sep 20th, 2021 - To study the effect of dapagliflozin vs sitagliptin on liver fat accumulation in patients with diabetes and liver transplantation Material and Methods Ethical considerations The trial protocol will be submitted to Medanta ethics committees for app...

Sep 26th, 2021 - Key clinical point: Blood specimens from patients with chronic pancreatitis (CP) yielded a panel of 6 metabolites that showed differential expression with the presence or absence of exocrine pancreatic insufficiency (EPI; fecal elastase < 200 mg/g.

Aug 31st, 2021 - Akash Goel, MD In recent months, there have been multiple publications around novel diagnostic testing which both might help to identify patients at risk for exocrine pancreatic insufficiency (EPI) and its clinical sequela. Our first study comes o.

Aug 28th, 2021 - Key clinical point: The prevalence of exocrine pancreatic insufficiency (EPI) was higher in patients with diffuse echogenicity of the pancreas on endoscopic ultrasound (EUS; fatty pancreas group) vs patients with chronic diarrhea without known pan.

Mar 31st, 2021 - Akash Goel, MD This month’s selection of EPI research includes a few very clinically relevant and high-quality studies. The first of which comes out of University of Miami, by father and son authors Barkin.

Jan 26th, 2021 - Pancreatic enzyme replacement therapy (PERT) is often an essential component of the treatment regimen for patients with pancreatic cancer, but it can be very pricey. "Out-of-pocket costs for a 30-day supply of enzymes for Medicare beneficiaries ca...