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ALLMedicine™ Helicobacter Pylori Infection Center

Research & Reviews  1,603 results

Activation of Aquaporin 5 by carcinogenic Helicobacter pylori infection promotes epithe...
https://doi.org/10.1111/hel.12842
Helicobacter Li N, Xu X et. al.

Aug 1st, 2021 - Helicobacter pylori (H. pylori) is a major risk factor for gastric cancer. The water channel protein Aquaporin 5 (AQP5) is involved in the tumorigenesis and progression of various cancers. In this study, we aimed to explore the role of AQP5 in H. ...

Novel "High-dose Quad" Salvage Therapy Approach for Helicobacter pylori Infection: A Ca...
https://doi.org/10.1177/08971900211033143
Journal of Pharmacy Practice; Bricker-Ford R

Jul 17th, 2021 - Purpose: This case report outlines the successful eradication of chronic Helicobacter pylori (H. pylori) infection using a novel, "high-dose quad" salvage therapy approach. Gastroenterologists may consider using this approach for patients who have...

Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immuno...
https://doi.org/10.1136/gutjnl-2020-323392
Gut Oster P, Vaillant L et. al.

Jul 14th, 2021 - In this study, we determined whether Helicobacter pylori (H. pylori) infection dampens the efficacy of cancer immunotherapies. Using mouse models, we evaluated whether immune checkpoint inhibitors or vaccine-based immunotherapies are effective in ...

Different dose of new generation proton pump inhibitors for the treatment of Helicobact...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274125
International Journal of Immunopathology and Pharmacology; Gao W, Zhang X et. al.

Jul 13th, 2021 - The evidence on whether high-dose new generation proton pump inhibitors (PPIs) including rabeprazole and esomeprazole achieve a higher eradication rate of Helicobacter pylori has not been assessed. The primary comparison was eradication and advers...

Helicobacter pylori infection causes both protective and deleterious effects in human h...
https://doi.org/10.1038/s41435-021-00146-4 10.3322/caac.21492 10.1016/S0140-6736(17)33326-3 10.1053/j.gastro.2015.01.040 10.1053/j.gastro.2017.04.022 10.1111/jgh.12315 10.1002/ijc.11306 10.1007/s40142-018-0153-x 10.1158/1055-9965.EPI-13-1057 10.1073/pnas.95.21.12619 10.1016/j.bj.2015.06.002 10.1053/j.gastro.2009.01.073 10.1128/CMR.00011-10 10.1126/science.aad2545 10.1371/journal.ppat.1002693 10.1126/science.1080857 10.1038/srep14333 10.1242/dmm.027649 10.1186/1756-0381-7-10 10.3748/wjg.v25.i42.6289 10.1073/pnas.0506655103 10.1016/j.jaci.2019.10.022 10.1136/gut.2007.133462 10.1513/pats.201108-048MS 10.1128/iai.61.5.1799-1809.1993 10.3390/toxins10040163 10.1111/hel.12409 10.1186/s12862-016-0619-y 10.1186/s12915-018-0550-3 10.1080/21505594.2018.1532243 10.1371/journal.pone.0077358 10.1093/femsle/fnw296 10.1371/journal.pgen.1006546 10.1038/s41396-020-00758-0 10.1128/JB.00063-10 10.1038/35006081 10.1016/S0016-5085(03)00157-4 10.1038/ng.978 10.1038/ng.649 10.1038/ng.152 10.1002/mc.22063 10.1136/gutjnl-2019-318760 10.1111/cas.13815 10.1038/ng.3342 10.1007/s00439-016-1687-1 10.1007/s10620-018-5223-0 10.3748/wjg.v16.i10.1201 10.1016/j.celrep.2016.01.017 10.1136/gutjnl-2012-303018 10.1016/j.trstmh.2011.09.001 10.1371/journal.pone.0032106 10.1016/S0140-6736(84)91816-6 10.1016/j.trsl.2020.12.006 10.1007/s10620-018-5174-5 10.5114/aoms.2019.83699 10.1016/0140-6736(91)92035-Z 10.1182/blood-2009-06-228015 10.1016/0140-6736(93)91409-F 10.25122/jml-2018-0035 10.1016/j.micpath.2020.104572 10.1371/journal.pone.0184046 10.1097/MOG.0b013e32833efede 10.7326/0003-4819-120-12-199406150-00001 10.1111/nyas.14449 10.1016/j.waojou.2019.100035 10.1086/590158 10.1001/archinte.167.8.821 10.1016/j.aller.2017.03.004 10.5812/jjm.8(5)2015.17842 10.1371/journal.pone.0004060 10.1093/tropej/fmm040 10.1172/JCI79337 10.1111/apt.13572 10.1002/ppul.24905 10.18683/germs.2019.1174 10.1186/1471-230X-11-37 10.1159/000508330 10.1159/000500598 10.1111/apt.15770 10.1002/ibd.21116 10.1086/315887 10.1023/A:1015618112695 10.1371/journal.pone.0008804 10.1073/pnas.1318093111 10.1038/nature05562 10.3389/fgene.2014.00290 10.3389/fmicb.2020.601839 10.3748/wjg.v23.i23.4158 10.1371/journal.pone.0176454 10.4103/ijmm.IJMM_19_158 10.1016/j.meegid.2016.06.044 10.1093/jnci/djq325 10.1016/j.canep.2016.03.008 10.1007/s12029-014-9672-1 10.1159/000093816 10.1007/s00415-010-5824-9 10.2147/VHRM.S28680 10.1111/hel.12364 10.21037/atm-20-4863 10.1093/aje/kwt234 10.3748/wjg.v18.i10.1093 10.1093/infdis/jis106
Genes and Immunity; Miller AK, Williams SM

Jul 11th, 2021 - Infection with Helicobacter pylori (H. pylori) is necessary but not sufficient for the development of gastric cancer, the third leading cause of cancer death globally. H. pylori infection affects over half of people globally; however, it does not ...

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Guidelines  6 results

AGA Clinical Practice Update on the Management of Refractory Helicobacter pylori Infect...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281326
Gastroenterology Shah SC, Iyer PG et. al.

Feb 2nd, 2021 - The purpose of this CPU Expert Review is to provide clinicians with guidance on the management of Helicobacter pylori after an initial attempt at eradication therapy fails, including best practice advice on specific regimen selection, and consider...

British Society of Gastroenterology guidelines on the diagnosis and management of patie...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709778
Gut Banks M, Graham D et. al.

Jul 7th, 2019 - Gastric adenocarcinoma carries a poor prognosis, in part due to the late stage of diagnosis. Risk factors include Helicobacter pylori infection, family history of gastric cancer-in particular, hereditary diffuse gastric cancer and pernicious anaem...

Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children...
https://doi.org/10.1097/MPG.0000000000001594
Journal of Pediatric Gastroenterology and Nutrition; Jones NL, Koletzko S et. al.

May 26th, 2017 - Because of the changing epidemiology of Helicobacter pylori infection and low efficacy of currently recommended therapies, an update of the European Society for Paediatric Gastroenterology Hepatology and Nutrition/North American Society for Pediat...

ACG Clinical Guideline: Treatment of Helicobacter pylori Infection.
https://doi.org/10.1038/ajg.2016.563
The American Journal of Gastroenterology; Chey WD, Leontiadis GI et. al.

Jan 11th, 2017 - Helicobacter pylori (H. pylori) infection is a common worldwide infection that is an important cause of peptic ulcer disease and gastric cancer. H. pylori may also have a role in uninvestigated and functional dyspepsia, ulcer risk in patients taki...

Evidence-based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection i...
https://doi.org/10.1097/MPG.0b013e3182227e90
Journal of Pediatric Gastroenterology and Nutrition; Koletzko S, Jones NL et. al.

May 12th, 2011 - As the clinical implications of Helicobacter pylori infection in children and adolescents continue to evolve, ESPGHAN and NASPGHAN jointly renewed clinical guidelines using a standardized evidence-based approach to develop updated recommendations ...

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Drugs  59 results see all →

Clinicaltrials.gov  51 results

Efficacy and Safety of 14-day Concomitant Therapy for Helicobacter Pylori Infection
https://clinicaltrials.gov/ct2/show/NCT03726099

Feb 21st, 2020 - Helicobacter pylori infects half of the world's population. H.pylori eradication is an effective approach to reduce the risk of developing gastric cancer. However, eradication rates of first-line therapy decreased over years due to the rapidly inc...

The Effect of Miswak Chewing Sticks on the Oral Helicobacter Pylori Infection
https://clinicaltrials.gov/ct2/show/NCT02418520

Oct 14th, 2019 - Aim / Primary objective: To elucidate the relationship of chewing miswak sticks on the H. Pylori infection in the oral cavity. Specific Objectives To find the prevalence of oral H.Pylori among the Kuwaiti Population To compare the reduction in cou...

Helicobacter Pylori Eradication Rates of Bismuth-containing Quadruple Therapy vs Modified Quadruple Therapy in Korea
https://clinicaltrials.gov/ct2/show/NCT03665428

Jul 30th, 2019 - South Korea has the highest incidence of gastric cancer worldwide and Helicobacter pylori infection is still prevalent. Clarithromycin-containing triple therapy is still the primary therapy approved by the Korean government. However, studies of an...

Comparison of Two Rescue Therapies for Helicobacter Pylori Infection
https://clinicaltrials.gov/ct2/show/NCT02547012

Mar 14th, 2019 - The H pylori-infected adult patients with failure of standard triple therapy and H pylori-infected adult patients with failure of non-bismuth quadruple therapy are randomly assigned to either EALT (esomeprazole 40 mg b.d., amoxicillin 500 mg q.d.s...

Efficacies of Antimicrobial Susceptibility-Guided Versus Empirical Therapy for Rescue Treatment of Helicobacter Pylori Infection
https://clinicaltrials.gov/ct2/show/NCT03658746

Dec 24th, 2018 - Helicobacter pylori(H.pylori), which infects about 50% of the global population, has been classified as the first risk factor of gastric cancer. Strong evidence supports that H.pylori eradication is an effective approach to reduce the incidence of...

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News  98 results

First-Line H pylori Regimens Ranked by Comparative Effectiveness
https://www.medscape.com/viewarticle/954605

Jul 12th, 2021 - A network meta-analysis of current first-line dual, triple, and quadruple therapies for Helicobacter pylori infection found that vonoprazan triple therapy was most effective, while standard triple therapy of a proton pump inhibitor (PPI), amoxicil...

AGA Clinical Practice Update: Eradication Strategies for H. pylori Infection
https://www.medscape.com/viewarticle/949814

Apr 23rd, 2021 - Antimicrobial resistance is the most common cause of treatment-refractory Helicobacter pylori infection, but before switching antibiotics, clinicians should screen for factors such as treatment nonadherence or inadequate suppression of gastric aci...

H Pylori Eradication Testing Less Likely in Black Patients
https://www.medscape.com/viewarticle/940437

Nov 5th, 2020 - Black patients may be significantly less likely to receive eradication testing after treatment for Helicobacter pylori infection than patients of other races/ethnic groups, based on a retrospective analysis of more than 1,700 individuals. This dis...

Global Stomach Cancer Deaths Decline as CRC Deaths Stagnate, Rise
https://www.staging.medscape.com/viewarticle/938086

Sep 25th, 2020 - A global analysis of premature deaths from noncommunicable diseases (NCDs) has shown mixed results for gastrointestinal (GI) cancers. The data suggest fewer people are dying from stomach cancer, but in some countries, the risk of colorectal cancer...

H pylori Therapy Reduces Gastric Cancer in High-Risk Patients
https://www.medscape.com/viewarticle/924545

Jan 30th, 2020 - UPDATED with comments  January 31, 2020 // Treatment of Helicobacter pylori infection in patients with a family history of gastric cancer more than halves their risk of developing gastric cancer, according to the results of a large-scale, long-ter...

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Patient Education  2 results see all →