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About 4,043 results

ALLMedicine™ Familial Adenomatous Polyposis Center

Research & Reviews  1,981 results

Case report of adrenocortical carcinoma associated with double germline mutations in MS...
https://doi.org/10.1002/ajmg.a.62099
American Journal of Medical Genetics. Part A; Raygada M, Raffeld M et. al.

Feb 22nd, 2021 - Adrenocortical carcinoma (ACC) is a rare aggressive malignancy that originates in the outer layer of the adrenal gland. Most ACCs are sporadic, but a small percentage of cases are due to hereditary cancer syndromes such as Li-Fraumeni syndrome (LF...

Endoscopic submucosal dissection for polyps in the anal transitional zone after ileoana...
https://doi.org/10.1055/a-1346-8903
Endoscopy O'Neill C, Barreiro P et. al.

Feb 16th, 2021 - Endoscopic submucosal dissection for polyps in the anal transitional zone after ileoanal anastomosis in a patient with familial adenomatous polyposis.|2021|O'Neill C,Barreiro P,Mendo R,Félix C,Costa I,|

Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice.
https://doi.org/10.1016/j.ajpath.2021.01.010
The American Journal of Pathology; Zhang Y, Liang B et. al.

Feb 5th, 2021 - Hepatocellular carcinoma (HCC) and hepatoblastoma are the major types of primary liver cancer in adulthood and childhood, respectively. Wnt/β-catenin signaling deregulation is one of the most frequent genetic events in hepatocarcinogenesis. APC re...

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Guidelines  3 results

Hereditary Gastrointestinal Cancers: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
https://academic.oup.com/annonc/advance-article-pdf/doi/10.1093/annonc/mdz233/29094053/mdz233.pdf

Aug 4th, 2019 - Knowledge of genetic susceptibility to gastrointestinal cancers is constantly evolving with identification of new genes. Similarly, a better understanding of the genotype/phenotype relationship in patients with Lynch syndrome (LS) or familial aden...

Guide to endoscopy of the ileo-anal pouch following restorative proctocolectomy with il...
https://doi.org/10.1002/ibd.20874
Inflammatory Bowel Diseases; McLaughlin SD, Clark SK et. al.

Jan 30th, 2009 - Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis is the surgical procedure of choice for patients with ulcerative colitis (UC). It is also performed in selected patients with familial adenomatous polyposis (FAP). A significant p...

Guidelines for the clinical management of familial adenomatous polyposis (FAP).
https://doi.org/10.1136/gut.2007.136127
Gut Vasen HF, Möslein G et. al.

Jan 15th, 2008 - Familial adenomatous polyposis (FAP) is a well-described inherited syndrome, which is responsible for <1% of all colorectal cancer (CRC) cases. The syndrome is characterised by the development of hundreds to thousands of adenomas in the colorectum...

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Clinicaltrials.gov  2,017 results

Case report of adrenocortical carcinoma associated with double germline mutations in MS...
https://doi.org/10.1002/ajmg.a.62099
American Journal of Medical Genetics. Part A; Raygada M, Raffeld M et. al.

Feb 22nd, 2021 - Adrenocortical carcinoma (ACC) is a rare aggressive malignancy that originates in the outer layer of the adrenal gland. Most ACCs are sporadic, but a small percentage of cases are due to hereditary cancer syndromes such as Li-Fraumeni syndrome (LF...

Endoscopic submucosal dissection for polyps in the anal transitional zone after ileoana...
https://doi.org/10.1055/a-1346-8903
Endoscopy O'Neill C, Barreiro P et. al.

Feb 16th, 2021 - Endoscopic submucosal dissection for polyps in the anal transitional zone after ileoanal anastomosis in a patient with familial adenomatous polyposis.|2021|O'Neill C,Barreiro P,Mendo R,Félix C,Costa I,|

Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice.
https://doi.org/10.1016/j.ajpath.2021.01.010
The American Journal of Pathology; Zhang Y, Liang B et. al.

Feb 5th, 2021 - Hepatocellular carcinoma (HCC) and hepatoblastoma are the major types of primary liver cancer in adulthood and childhood, respectively. Wnt/β-catenin signaling deregulation is one of the most frequent genetic events in hepatocarcinogenesis. APC re...

see more →

News  31 results

Secondary bile acid deficiency may be culprit in UC inflammation
https://www.mdedge.com/gihepnews/article/218027/gastroenterology/secondary-bile-acid-deficiency-may-be-culprit-uc?channel=345
Richard Mark Kirkner, MDedge News

Feb 27th, 2020 - Researchers have found three potential gut mechanisms linked to secondary bile acid (SBA) deficiencies implicated in intestinal inflammation in ulcerative colitis (UC), and reported that supplementation may aid in restoring bile acid levels and po.

Hereditary Gastrointestinal Cancers: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
https://academic.oup.com/annonc/advance-article-pdf/doi/10.1093/annonc/mdz233/29094053/mdz233.pdf

Aug 4th, 2019 - Knowledge of genetic susceptibility to gastrointestinal cancers is constantly evolving with identification of new genes. Similarly, a better understanding of the genotype/phenotype relationship in patients with Lynch syndrome (LS) or familial aden...

Sorafenib Improves Survival for Patients With Rare Sarcomas
https://www.mdedge.com/fedprac/avaho/article/165563/oncology/sorafenib-improves-survival-patients-rare-sarcomas
Jan Dyer

May 10th, 2018 - Promising results from a phase 3 trial could represent a paradigm shift in treatment of patients with desmoid tumors, say National Cancer Institute (NCI) researchers. Sorafenib tosylate extended progression-free survival (PFS) compared with that o.

Bacteria Identified as Oncogenic Drivers in Hereditary Cancer
https://www.medscape.com/viewarticle/892280

Feb 4th, 2018 - Two common species of bacteria and the biofilms they create have been identified as key oncogenic drivers in the process leading to colorectal cancer (CRC) in patients with familial adenomatous polyposis (FAP), and potentially sporadic forms of CR...

Sulindac-erlotinib as chemoprevention for FAP
https://www.mdedge.com/gihepnews/article/143438/gi-oncology/sulindac-erlotinib-chemoprevention-fap
N. Jewel Samadder, MD, MSc, FRCP

Jul 27th, 2017 - Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disorder caused by germline mutations in the APC (adenomatous polyposis coli) gene. The disease is characterized by the formation of hundreds to thousands of adenomatous polyp.

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Patient Education  11 results see all →