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About 4,185 results

ALLMedicine™ Hemochromatosis Center

Research & Reviews  1,971 results

Iron overload in aging Bmp6‑/‑ mice induces exocrine pancreatic injury and fibrosis due...
https://doi.org/10.3892/ijmm.2021.4893
International Journal of Molecular Medicine; Pauk M, Kufner V et. al.

Mar 2nd, 2021 - The relationship between hemochromatosis and diabetes has been well established, as excessive iron deposition has been reported to result in impaired function of the endocrine and exocrine pancreas. Therefore, the objective of the present study wa...

PIGA Mutations Can Mimic Neonatal Hemochromatosis.
https://doi.org/10.1542/peds.2020-0918
Pediatrics Flores-Torres J, Carver JD et. al.

Feb 26th, 2021 - Neonatal hemochromatosis (NH), one of the most common causes of liver failure in the neonate, often causes fetal loss or death during the neonatal period. Most cases are thought to be due to gestational alloimmune disease; however, other rare caus...

Erythropoietin Concentration in Boys With p.His63Asp Polymorphism of the HFE Gene.
https://doi.org/10.1097/MPH.0000000000002126
Journal of Pediatric Hematology/oncology; Kaczorowska-Hac B, Luszczyk M et. al.

Feb 24th, 2021 - The molecular mechanism that regulates iron homeostasis is based on a network of signals, which reflect on the iron requirements of the body. HFE-related hemochromatosis is characterized by excessive intestinal absorption of dietary iron, in parti...

Hemochromatosis, alcoholism and unhealthy dietary fat: a case report.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888131
Journal of Medical Case Reports; Shobi V, Adeseye A et. al.

Feb 18th, 2021 - Hereditary hemochromatosis is an autosomal recessive disorder where the clinical phenotype of skin pigmentation and organ damage occurs only in homozygotes. Simple heterozygotes, that is, just C282Y, typically do not develop iron overload. Here we...

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Guidelines  17 results

ACG Clinical Guideline: Hereditary Hemochromatosis
https://journals.lww.com/ajg/Fulltext/2019/08000/ACG_Clinical_Guideline__Hereditary_Hemochromatosis.11.aspx
Kowdley,K.,et al

Aug 1st, 2019 - Hereditary hemochromatosis (HH) is one of the most common genetic disorders among persons of northern European descent. There have been recent advances in the diagnosis, management, and treatment of HH. The availability of molecular diagnostic tes...

ACG Clinical Guideline: Hereditary Hemochromatosis.
https://doi.org/10.14309/ajg.0000000000000315
The American Journal of Gastroenterology; Kowdley KV, Brown KE et. al.

Jul 24th, 2019 - Hereditary hemochromatosis (HH) is one of the most common genetic disorders among persons of northern European descent. There have been recent advances in the diagnosis, management, and treatment of HH. The availability of molecular diagnostic tes...

Direct-to-consumer genetic testing
https://www.ama-assn.org/delivering-care/precision-medicine/direct-consumer-genetic-testing

Apr 2nd, 2019 - Types of DTC genetic tests A broad range of genetic test types are offered DTC, including: Carrier testing for diseases such as cystic fibrosis and hemochromatosis Pharmacogenomic testing Testing for predisposition to complex diseases such as her...

Guidelines Insights: Hepatobiliary Cancers, Version 2.2019
https://jnccn.org/view/journals/jnccn/17/4/article-p302.xml
Benson,A.,et al

Mar 31st, 2019 - Incidence and mortality rates for cancer overall are declining, but both incidence and mortality rates for hepatocellular carcinoma (HCC) are increasing.1,2 Risk factors for development of HCC include infection with hepatitis B virus (HBV) and/or ...

Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous ...
https://link.springer.com/article/10.1007%2Fs12072-018-9855-0
Adams, P.,et al.

Mar 30th, 2018 - Although guidelines are available for hereditary hemochromatosis, a high percentage of the recommendations within them are not shared between the different guidelines. Our main aim is to provide an objective, simple, brief, and practical set of re.

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Drugs  4 results see all →

Clinicaltrials.gov  2,067 results

Iron overload in aging Bmp6‑/‑ mice induces exocrine pancreatic injury and fibrosis due...
https://doi.org/10.3892/ijmm.2021.4893
International Journal of Molecular Medicine; Pauk M, Kufner V et. al.

Mar 2nd, 2021 - The relationship between hemochromatosis and diabetes has been well established, as excessive iron deposition has been reported to result in impaired function of the endocrine and exocrine pancreas. Therefore, the objective of the present study wa...

PIGA Mutations Can Mimic Neonatal Hemochromatosis.
https://doi.org/10.1542/peds.2020-0918
Pediatrics Flores-Torres J, Carver JD et. al.

Feb 26th, 2021 - Neonatal hemochromatosis (NH), one of the most common causes of liver failure in the neonate, often causes fetal loss or death during the neonatal period. Most cases are thought to be due to gestational alloimmune disease; however, other rare caus...

Erythropoietin Concentration in Boys With p.His63Asp Polymorphism of the HFE Gene.
https://doi.org/10.1097/MPH.0000000000002126
Journal of Pediatric Hematology/oncology; Kaczorowska-Hac B, Luszczyk M et. al.

Feb 24th, 2021 - The molecular mechanism that regulates iron homeostasis is based on a network of signals, which reflect on the iron requirements of the body. HFE-related hemochromatosis is characterized by excessive intestinal absorption of dietary iron, in parti...

Hemochromatosis, alcoholism and unhealthy dietary fat: a case report.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888131
Journal of Medical Case Reports; Shobi V, Adeseye A et. al.

Feb 18th, 2021 - Hereditary hemochromatosis is an autosomal recessive disorder where the clinical phenotype of skin pigmentation and organ damage occurs only in homozygotes. Simple heterozygotes, that is, just C282Y, typically do not develop iron overload. Here we...

see more →

News  107 results

Common Genetic Disorder Tied to Increased Dementia Risk in Men
https://www.medscape.com/viewarticle/945393

Feb 4th, 2021 - Men with iron overload due to hereditary hemochromatosis are at increased risk of developing dementia, an analysis of UK Biobank data indicates. Results of a large analysis showed that among men who had two mutations that cause hemochromatosis (HF...

New Guidelines to Help You Manage Hereditary Hemochromatosis
https://www.medscape.com/viewarticle/926286

Mar 15th, 2020 - This transcript has been edited for clarity. Hello. I'm Dr David Johnson, professor of medicine and chief of gastroenterology at Eastern Virginia Medical School in Norfolk, Virginia. Welcome back to another GI Common Concerns. This past week, I sa...

Sixty-five roses
https://www.mdedge.com/node/210356/path_term/51947
Brett M. Coldiron, MD

Oct 19th, 2019 - Like many of you, my wife and I took the DNA plunge for fun and spit in the cup. She is genetically perfect, but I, however, am a carrier for alpha-1 anti-trypsin deficiency, hemochromatosis, and like 1 in 19 Irish people, cystic fibrosis.

ACG Clinical Guideline: Hereditary Hemochromatosis
https://journals.lww.com/ajg/Fulltext/2019/08000/ACG_Clinical_Guideline__Hereditary_Hemochromatosis.11.aspx
Kowdley,K.,et al

Aug 1st, 2019 - Hereditary hemochromatosis (HH) is one of the most common genetic disorders among persons of northern European descent. There have been recent advances in the diagnosis, management, and treatment of HH. The availability of molecular diagnostic tes...

May 2019 - Question 1
https://www.mdedge.com/gihepnews/article/199937/mixed-topics/may-2019-question-1?channel=27442

Apr 30th, 2019 - Q1. Correct Answer: A Rationale: This is an example of Yersinia infection.

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Patient Education  19 results see all →