ALLMedicine™ Familial Adenomatous Polyposis Center

Mar 24th, 2023 - Since cancer development is inevitable in patients with familial adenomatous polyposis (FAP), we aimed to determine the incidence of incidental malignancy in prophylactic colectomy specimens. The files of patients who underwent prophylactic surger...

Mar 23rd, 2023 - Practice Essentials Gardner syndrome, a variant of familial adenomatous polyposis (FAP), [1] is an autosomal dominant disease characterized by GI polyps, multiple osteomas, and skin and soft tissue tumors. Cutaneous findings [2] of Gardner syndrom...

Mar 23rd, 2023 - Practice Essentials Gardner syndrome, a variant of familial adenomatous polyposis (FAP),[1] is an autosomal dominant disease characterized by GI polyps, multiple osteomas, and skin and soft tissue tumors. Cutaneous findings[2] of Gardner syndrome ...

Mar 23rd, 2023 - Practice Essentials Gardner syndrome, a variant of familial adenomatous polyposis (FAP), [1] is an autosomal dominant disease characterized by GI polyps, multiple osteomas, and skin and soft tissue tumors. Cutaneous findings [2] of Gardner syndrom...

Mar 21st, 2023 - Clinical experience teaches that intraperitoneal adhesions are more severe in patients with familial adenomatous polyposis than in patients without it. This impression may come from the common association of familial adenomatous polyposis with des...

Feb 4th, 2015 - This guideline presents recommendations for the management of patients with hereditary gastrointestinal cancer syndromes. The initial assessment is the collection of a family history of cancers and premalignant gastrointestinal conditions and shou...

Dec 3rd, 2014 - To provide recommendations on prevention, screening, genetics, treatment, and management for people at risk for hereditary colorectal cancer (CRC) syndromes. The American Society of Clinical Oncology (ASCO) has a policy and set of procedures for e...

Jan 31st, 2009 - Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis is the surgical procedure of choice for patients with ulcerative colitis (UC). It is also performed in selected patients with familial adenomatous polyposis (FAP). A significant p...

Mar 15th, 2023 - Familial adenomatous polyposis (FAP) is the most common polyposis syndrome. It is an autosomal dominant inherited disorder characterized by the early onset of hundreds to thousands of adenomatous polyps throughout the colon. JNJ-64251330 (lorpucit...

Feb 24th, 2023 - This is a Phase 2, randomized, double-blind, placebo-controlled trial to evaluate efficacy, safety, and pharmacokinetics of REC-4881 in participants with Familial Adenomatous Polyposis (FAP).

Feb 21st, 2023 - PRIMARY OBJECTIVE: I. To evaluate the effect of treatment with OCA versus treatment with placebo on duodenal polyp burden (sum of polyp diameters) in participants with FAP. SECONDARY OBJECTIVES: I. To assess the safety profile of treatment with OC...

Feb 21st, 2023 - PRIMARY OBJECTIVE: I. To evaluate the effect of treatment with OCA versus treatment with placebo on duodenal polyp burden (sum of polyp diameters) in participants with FAP. SECONDARY OBJECTIVES: I. To assess the safety profile of treatment with OC...

Feb 13th, 2023 - Celecoxib is a drug that was developed to treat arthritis. However, celecoxib may also help to stop or slow the growth of colon and rectal tumor cells. At the start of the study, you will be asked questions about your medical history, have a compl...

Oct 31st, 2022 - Prognosis, treatment outcomes, and molecular characteristics have become associated with sidedness in colorectal cancers (CRCs) making the distinction an essential characteristic for consideration in decison-making.1 Right-sided CRCs (derived from...

Sep 27th, 2022 - Desmoid tumors, also known as aggressive fibromatosis, share some characteristics with cancers, specifically unchecked cell growth. However, it is not accurate to call them a cancer. That is the first thing Dale R. Shepard, MD, PhD, says to patien...

Aug 30th, 2022 - The study covered in this summary was published on ResearchSquare.com as a preprint and has not yet been peer reviewed. Key Takeaway This study reported that patients with visceral adiposity, including patients with diabetes and metabolic syndrome...

Aug 25th, 2022 - How soon after a COVID-19 infection is it OK to administer biologics for patients with inflammatory bowel disease (IBD)? (Clinical Gastroenterology and Hepatology) Compared with second-dose side effects, gastrointestinal symptoms were slightly wor...

Aug 23rd, 2022 - Use of the epidermal growth-factor receptor inhibitor erlotinib led to about a 30% reduction in duodenal polyp burden after 6 months of once-weekly treatment for patients with familial adenomatous polyposis (FAP) in a phase 2 clinical trial. "If e...