About 2,018 results

ALLMedicine™ Familial Adenomatous Polyposis Center

Research & Reviews  732 results

Functional outcomes, quality of life, sexual function, and fertility of adult patients ...
Journal of Pediatric Surgery; Henderson L, Lane V et. al.

Dec 2nd, 2021 - We conducted a questionnaire-based study of pouch function, quality of life, sexual function, and fertility among patients who had undergone ileal pouch anal anastomosis (IPAA) in childhood and who are now more than 18 years old. A consecutive ser...

Ileal Pouch Anal Anastomosis Is More "Desmoidogenic" Than Ileorectal Anastomosis in Fam...
Diseases of the Colon and Rectum; Sommovilla J, Liska D et. al.

Nov 30th, 2021 - Desmoid disease is a leading cause of morbidity and mortality in patients with familial adenomatous polyposis. Abdominal desmoid disease usually follows total proctocolectomy with ileal pouch anal anastomosis or total abdominal colectomy with ileo...

Evaluation of Classic, Attenuated, and Oligopolyposis of the Colon.
Gastrointestinal Endoscopy Clinics of North America; Long JM, Powers JM et. al.

Nov 21st, 2021 - The goal of this review is to provide an overview of evaluating patients with adenomatous polyposis of the colon, including elements such as generating a differential diagnosis, referral considerations for genetic testing, genetic testing options,...

Endoscopic Management and Surgical Considerations for Familial Adenomatous Polyposis.
Gastrointestinal Endoscopy Clinics of North America; Stanich PP, Sullivan B et. al.

Nov 21st, 2021 - Familial adenomatous polyposis (FAP) is the development of many adenomatous colorectal polyps. Colonoscopy is recommended to start at age 10 to 12 years at intervals of 1 to 2 years. Colectomy is clearly indicated for malignancy or significant col...

Chemoprevention Considerations in Patients with Hereditary Colorectal Cancer Syndromes.
Gastrointestinal Endoscopy Clinics of North America; Macaron C, Mankaney GN et. al.

Nov 21st, 2021 - Secondary prevention of colorectal neoplasia with chemoprevention is long-studied area of research and clinical use in patients with the 2 most common hereditary colorectal cancer syndromes including Lynch syndrome and familial adenomatous polypos...

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Guidelines  3 results

ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal c...
The American Journal of Gastroenterology; Syngal S, Brand RE et. al.

Feb 4th, 2015 - This guideline presents recommendations for the management of patients with hereditary gastrointestinal cancer syndromes. The initial assessment is the collection of a family history of cancers and premalignant gastrointestinal conditions and shou...

Hereditary colorectal cancer syndromes: American Society of Clinical Oncology Clinical ...
Journal of Clinical Oncology : Official Journal of the Am... Stoffel EM, Mangu PB et. al.

Dec 3rd, 2014 - To provide recommendations on prevention, screening, genetics, treatment, and management for people at risk for hereditary colorectal cancer (CRC) syndromes. The American Society of Clinical Oncology (ASCO) has a policy and set of procedures for e...

Guide to endoscopy of the ileo-anal pouch following restorative proctocolectomy with il...
Inflammatory Bowel Diseases; McLaughlin SD, Clark SK et. al.

Jan 31st, 2009 - Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis is the surgical procedure of choice for patients with ulcerative colitis (UC). It is also performed in selected patients with familial adenomatous polyposis (FAP). A significant p...

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Clinicaltrials.gov  23 results

Trial of eRapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance

Nov 17th, 2021 - Patients with FAP who are undergoing endoscopic surveillance will be given eRapa at one of three escalating doses/ schedules (0.5mg every other day, 0.5mg daily every other week, or 0.5mg daily) for 12 months with the aim of reducing polyp burden....

Registry With Information About Colitis Ulcerosa and Familial Adenomatous Polyposis Patients

Oct 14th, 2021 - To improve the quality of the surgery of the pouch created in CU and FAP patients, the following information will be collected: Patients Characteristics, Operative Data, Postoperative Outcome and Functional Postoperative Recovery.

Intestinal Stem Cells Characterization

Aug 24th, 2021 - Intestinal organoids are 3D mini-guts produced in vitro based on intestinal stem cell (ISC) capabilities. These organoids contain all of the intestinal epithelial cells. The renewal of the two kinds of ISCs, which are present at the bottom of inte...

CryoBalloon Ablation for Treatment of Duodenal Adenomas

Aug 5th, 2021 - Duodenal adenomas are precursors to adenocarcinoma. Treatment with endoscopic polypectomy is technically challenging problematic and associated with a high rate of complication - overall 26%, with bleeding 22-40%, higher with larger polyps. Surger...

Post-Trial Access for Guselkumab in Participants With Familial Adenomatous Polyposis

Jul 2nd, 2021 - The purpose of this post-trial access (PTA) program is to provide guselkumab to participants with Familial Adenomatous Polyposis (FAP) who are experiencing clinical benefit after completing 48 weeks of treatment in Study CNTO1959COR1001.

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News  37 results

Dr. Wilky on the Diagnosis and Management of Desmoid Tumors

Nov 22nd, 2021 - Breelyn Wilky, MD, director, Sarcoma Medical Oncology, deputy associate director, Clinical Research, associate professor, Medicine-Medical Oncology, University of Colorado Medicine, discusses the diagnosis and management of desmoid tumors. Desm...

Colorectal Cancer: A Review

Oct 4th, 2021 - Abstract Colorectal cancer is the third most common type of cancer diagnosed in the United States and is the third most common cause of cancer-related death. The majority of cases are sporadic, with hereditary colon cancer contributing up to 15%...

Genetic Counseling in Cancer Care: What Is the Role of Oncology Nurses?

Aug 25th, 2021 - If you saw a patient who was under 50 and had breast, colon, or ovarian cancer, what course of action would you recommend? What if the patient was a woman with more than 1 type of cancer, or a man with both colon and bladder cancers? If your respo...

Observation May Be Preferrable to Surgery in Certain Cases of Desmoid Tumor Fibromatosis

Apr 29th, 2021 - The local recurrence rate after surgical excision was similar to the rate of progression with active surveillance in patients with extra-abdominal desmoid tumor fibromatosis (DTF), suggesting that observation may be sufficient in some cases of DTF...

Chemoprevention With Low-Dose Aspirin Promising in Familial Adenomatous Polyposis

Apr 9th, 2021 - NEW YORK (Reuters Health) - Low-dose aspirin can suppress the recurrence of colorectal polyps larger than 5.0 mm in patients with familial adenomatous polyposis (FAP), according to results of the J-FAPP Study IV. "Because colorectal polyps larger ...

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Patient Education  12 results see all →