ALLMedicine™ Upper Gastrointestinal Bleeding Center

Mar 23rd, 2023 - Upper gastrointestinal bleeding (UGIB) in children has many causes, with its prevalence varying by age. Often presenting as hematemesis or melena, the initial treatment is stabilization of the patient, including protection of the airway, fluid res...

Mar 22nd, 2023 - Over-The-Scope Clips (OTSC) use have shown promising results for first line treatment of non-variceal upper gastrointestinal bleeding (NVUGIB). We conducted this meta-analysis to compare outcomes in patients treated with OTSC versus standard endos...

Mar 22nd, 2023 - Purpose: To investigate whether interindividual variability in the CYP2C9 (*2 and *3 alleles) and VKORC1 (rs9923231) genes is associated with increased risk of upper gastrointestinal bleeding (UGIB) in users of non-steroidal anti-inflammatory drug...

Mar 8th, 2023 - Background: Despite progressively reduced mortality over the last decades, cardiovascular disease remains the most common cause of death in both men and women in Sweden and the world. Ischemic heart disease with its acute presentation myocardial i...

Mar 7th, 2023 - What Is the Current Role of an Over-the-Scope Clip Used as First-Line Endoscopic Hemostasis in Patients With Nonvariceal Upper Gastrointestinal Bleeding?|2023|Barkun AN,Alali AA,|

May 1st, 2021 - We performed systematic reviews addressing predefined clinical questions to develop recommendations with the GRADE approach regarding management of patients with overt upper gastrointestinal bleeding. We suggest risk assessment in the emergency de...

Oct 22nd, 2019 - This update of the 2010 International Consensus Recommendations on the Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding (UGIB) refines previous important statements and presents new clinically relevant recommendations. An in...

May 6th, 2017 - Upper gastrointestinal bleeding (UGIB) remains a significant cause of morbidity and mortality with mortality rates as high as 14%. This document addresses the indications for imaging UGIB that is nonvariceal and unrelated to portal hypertension. T...

Feb 9th, 2016 - Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) is one of the most common medical emergencies in China and worldwide. In 2009, we published the "Guidelines for the diagnosis and treatment of acute non-variceal upper gastrointestinal b...

Jan 29th, 2013 - To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. A consensus committee of 68 international experts representing 30 international organizations was convened...

Mar 8th, 2023 - Background: Despite progressively reduced mortality over the last decades, cardiovascular disease remains the most common cause of death in both men and women in Sweden and the world. Ischemic heart disease with its acute presentation myocardial i...

Jan 27th, 2023 - Patients with active, non-variceal, upper gastrointestinal bleeding usually need an urgent endoscopic treatment. The standard therapy by application of an hemoclip and/or injection of an epinephrine solution is not always successful. Bipolar hemos...

Jan 26th, 2023 - Gastrointestinal bleeding is a frequent reason for consultation in the Emergency Department. It is a real emergency associated with fairly significant morbidity and mortality. The incidence of upper gastrointestinal bleeding (HDH) has been reporte...

Dec 21st, 2022 - Upper gastrointestinal bleeding (UGIB) remains an important medical emergency. While the annual incidence having decreased from about 100/100,000 adults in 1990s to 61-78/100,000 persons in 2009-2012 , 30-day mortality remains up to 11% . Despite ...

Dec 19th, 2022 - Despite major advances in the management of non-variceal upper gastrointestinal bleeding (NVUGIB) over the past decade including prevention of peptic ulcer bleeding, optimal use of endoscopic therapy and high-dose proton pump inhibition, this stil...

Dec 7th, 2022 - Nearly half of patients discharged from a hospital had inappropriate proton pump inhibitor (PPI) prescriptions, suggests a retrospective analysis of an Israeli healthcare database that showed no improvements in prescribing patterns over time. The ...

Nov 17th, 2022 - Onatasertib (ATG-008) plus toripalimab elicited an objective response rate (ORR) of 52.4% in patients with relapsed or metastatic cervical cancer, irrespective of PD-L1 expression, according to preliminary data from the phase 2 TORCH trial (NCT035...

Sep 2nd, 2022 - Note that some links may require subscriptions. Three deaths and another six infections stemming from a "pneumonia of unknown origin" have been reported in Argentina. (New York Post) The FDA announced a class I recall -- the most serious type -- o...

Aug 26th, 2022 - Warfarin is associated with higher rates of upper gastrointestinal (GI) bleeding but not overall or lower gastrointestinal bleeding rates compared with direct oral anticoagulants (DOACs), according to a new nationwide report from Iceland. In addit...

Aug 16th, 2022 - The use of warfarin was associated with higher rates of upper gastrointestinal bleeding, but not lower GI bleeding, compared with direct oral anticoagulants (DOACs), a population-based cohort study in Iceland showed. Among over 7,000 patients, rat...