ALLMedicine™ Hepatocellular Carcinoma Center
Research & Reviews 26,027 results
Antioxidants & Redox Signaling; Zhang Y, Zhang X et. al.
Jun 28th, 2022 - Hepatocellular carcinoma (HCC) is a liver malignancy with high mortality rate, limited treatment options and poor prognosis. Sorafenib has been the only systemic treatment option for patients with advanced HCC for more than a decade. While HCC is ...
Expert Review of Molecular Diagnostics; Temraz S, Nasr R et. al.
Jun 28th, 2022 - The diagnosis of hepatocellular carcinoma (HCC) is made at a relatively advanced stage resulting in poor prognosis. Alpha-fetoprotein and liver ultrasound have limited accuracy as biomarkers in HCC. Liver biopsy provides information on tumor biolo...
https://doi.org/10.1007/s00432-022-04126-7 10.1146/annurev-pathol-042020-042741 10.4137/CMO.S32821 10.3390/cancers14010233 10.1016/j.ccell.2015.08.004 10.1056/NEJM199910283411807 10.12998/wjcc.v3.i3.231 10.1016/S1470-2045(19)30396-1 10.1002/ijc.32041 10.1200/JCO.2017.75.3780 10.1200/JCO.2021.39.3_suppl.320 10.4143/crt.2019.493 10.1080/19420862.2018.1556465 10.1371/journal.pone.0212513 10.1016/S0140-6736(18)30207-1 10.3390/cancers13215257 10.3390/jcm9092854 10.1007/s40265-020-01286-z 10.1136/gutjnl-2018-316039 10.1200/JCO.2010.28.4075 10.1016/j.mrrev.2018.08.003 10.1038/ng.3375 10.1002/ijc.33013 10.1007/s40265-015-0383-0 10.1002/hep.30889 10.1016/j.jmoldx.2020.04.213 10.1038/s41375-019-0545-2 10.1080/14737140.2018.1470506 10.1177/1073274818789361 10.1016/S2468-1253(19)30086-X 10.1186/s12885-020-07365-4 10.21037/jgo.2018.08.18 10.1158/1078-0432.CCR-19-3561 10.1002/cam4.2381 10.1007/s00262-018-2160-x 10.1016/S1470-2045(09)70333-X 10.1007/978-3-319-91442-8_13
Journal of Cancer Research and Clinical Oncology; Wang L, Tang K et. al.
Jun 28th, 2022 - Gallbladder cancer (GBC) is a rare malignant tumour of the bile duct. Due to the lack of typical clinical manifestations in the early stage, it is basically at an advanced stage when discovered. Radical resection remains the only curative therapy ...
https://doi.org/10.1245/s10434-022-12000-6 10.1056/NEJMra1713263 10.1038/s41575-019-0186-y 10.1097/SLA.0b013e31821ad884 10.1053/j.gastro.2009.06.003 10.1245/s10434-012-2513-1 10.1245/s10434-008-0232-4 10.1016/S0168-8278(02)00360-4 10.1001/jamasurg.2015.4257 10.1007/s00261-018-1768-9 10.1007/s00330-018-5935-8 10.1148/radiol.2017170515 10.1016/j.jhep.2019.02.023 10.1002/hep.30814 10.1007/s12072-021-10183-w 10.1148/radiol.2021203614 10.1001/jamanetworkopen.2021.25055 10.1002/hep.27877 10.1038/s41551-018-0301-3 10.1038/s41591-019-0447-x 10.1002/jmri.27538 10.3390/cancers13102368 10.3389/fonc.2021.588010 10.1007/s00432-021-03617-3 10.1001/jama.2013.281053 10.1016/j.cld.2015.01.001 10.1016/j.csbj.2021.01.014 10.1007/s00432-020-03366-9 10.1002/hep.27760
Annals of Surgical Oncology; Chu T, Zhao C et. al.
Jun 27th, 2022 - Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer death worldwide, and the prognosis remains dismal. In this study, two pivotal factors, microvascular invasion (MVI) and vessels encapsulating tumor clusters (VETC) were preop...
Journal of Lipid Research; Khan TG, Ginsburg D et. al.
Jun 27th, 2022 - The low-density lipoprotein receptor (LDLR) mediates the hepatic uptake of circulating low-density lipoproteins (LDL), a process that modulates the development of atherosclerotic cardiovascular disease. We recently identified RAB10, encoding a sma...
Guidelines 37 results
Journal of Hepatology; ,
Jun 7th, 2022 - Haemochromatosis is characterised by elevated transferrin saturation (TSAT) and progressive iron loading that mainly affects the liver. Early diagnosis and treatment by phlebotomy can prevent cirrhosis, hepatocellular carcinoma, diabetes, arthropa...
Gastroenterology Su GL, Altayar O et. al.
Feb 26th, 2022 - Hepatocellular carcinoma (HCC), the most common primary liver cancer, remains a deadly cancer, with an incidence that has tripled in the United States since 1980. In recent years, new systemic therapies for HCC have been approved and a critical as...
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; , et. al.
Dec 21st, 2021 - Nonalcoholic fatty liver disease (NAFLD) is a common and emerging liver disease in adults, paralleling the epidemic of obesity and diabetes, and leading to worrisome events (hepatocellular carcinoma and end-stage liver disease). In the last years,...
Eating and Weight Disorders : EWD;
Dec 17th, 2021 - Nonalcoholic fatty liver disease (NAFLD) is a common and emerging liver disease in adults, paralleling the epidemic of obesity and diabetes and leading to worrisome events (hepatocellular carcinoma and end-stage liver disease). In the past years, ...
Practical Radiation Oncology; Apisarnthanarax S, Barry A et. al.
Oct 25th, 2021 - This guideline provides evidence-based recommendations for the indications and technique-dose of external beam radiation therapy (EBRT) in hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (IHC). The American Society for Radiation...
Drugs 22 results see all →
Clinicaltrials.gov 2,195 results
Jun 24th, 2022 - The purpose of this study is to determine the safety and efficacy of belzutifan in combination with pembrolizumab and lenvatinib in multiple solid tumors including hepatocellular carcinoma (HCC), colorectal cancer (CRC), pancreatic ductal adenocar...
Jun 24th, 2022 - Chronic hepatitis B affects at least 1.5 million Americans and is a major cause of cirrhosis, end-stage liver disease and hepatocellular carcinoma. Five oral antiviral agents have been licensed for use in chronic hepatitis B in the United States. ...
Jun 24th, 2022 - Background: Primary liver cancer (PLC) is the 2nd most common cause of cancer-related death worldwide and the one cancer with the fastest rising incidence and mortality in the U.S. PLC consists of two main histological subtypes, i.e., hepatocellul...
Jun 24th, 2022 - Pilot study to evaluate the combination of optical molecular imaging (OMI) and EM tracking in localizing intrahepatic lesions and assess the concordance between fluorescence ICG and histopathology for the diagnosis of liver cancer. Hepatocellular ...
Jun 24th, 2022 - This is a general clinical research protocol to allow for evaluation, investigation and long-term follow up of patients who have an acute or chronic liver disease. The protocol is designed to study the natural history and pathogenesis of various l...
News 1,531 results
Jun 23rd, 2022 - Key clinical point: Microwave ablation may be a safe and effective first-line locoregional therapy (LRT) for bridging patients with hepatocellular carcinoma (HCC) to liver transplant (LT), with no cases of waitlist removal due to tumor seeding, pr.
Jun 23rd, 2022 - Key clinical point: The pediatric hepatocellular carcinoma (HCC) subtypes fibrolamellar carcinoma (FLC) and conventional HCC (cHCC) can be considered nonequivalent entities because they show different anatomic patterns and outcomes together with t.
Jun 23rd, 2022 - Key clinical point: Stereotactic body radiotherapy (SBRT) plus transcatheter arterial chemoembolization (TACE) may be safe and more effective than either of the procedures alone (monotherapy) for treating inoperable hepatocellular carcinoma (HCC).
Jun 23rd, 2022 - Key clinical point: Atezolizumab plus bevacizumab (Atez/Bev) shows potent therapeutic efficacy against unresectable hepatocellular carcinoma (uHCC) in patients with a good hepatic function, classified as Child-Pugh A (CP-A), but has decreased effi.
Jun 23rd, 2022 - Key clinical point: Therapy with atezolizumab plus bevacizumab (Atez/Bev) vs. lenvatinib in the first-line setting may confer a survival benefit in patients with unresectable hepatocellular carcinoma (uHCC).