About 72,330 results

ALLMedicine™ Anemia Center

Research & Reviews  21,555 results

Trends in prevalence and treatment rate of anemia in the U.S. population: cross-section...
Hematology (Amsterdam, Netherlands); Wang C, Wang Y

Aug 14th, 2022 - To determine the trends in anemia prevalence, treatment rates, and their associated demographic and socioeconomic status factors in the U.S. nationally representative population. We extracted data from individuals ≥20-year-old from the NHANES from...

Arsenic impairs the lineage commitment of hematopoietic progenitor cells through the at...
Toxicology and Applied Pharmacology; Medina S, Zhang H et. al.

Aug 13th, 2022 - Arsenic exposure produces significant hematotoxicity in vitro and in vivo. Our previous work shows that arsenic (in the form of arsenite, AsIII) interacts with the zinc finger domains of GATA-1, inhibiting the function of this critical transcripti...

Pan-cancer efficacy of pralsetinib in patients with RET fusion-positive solid tumors fr...
Nature Medicine; Subbiah V, Cassier PA et. al.

Aug 13th, 2022 - Oncogenic RET fusions occur in diverse cancers. Pralsetinib is a potent, selective inhibitor of RET receptor tyrosine kinase. ARROW ( NCT03037385 , ongoing) was designed to evaluate pralsetinib efficacy and safety in patients with advanced RET-alt...

Oncostatin M: Risks and benefits of a Novel Therapeutic Target for Atherosclerosis.
Current Drug Targets; Rankouhi TR, Keulen DV et. al.

Aug 13th, 2022 - Cardiovascular disease (CVD) is a leading cause of death worldwide. It is predicted that approximately 23.6 million people will die from CVDs annually by 2030. Therefore, there is a great need for an effective therapeutic approach to combat this d...

Efficacy and safety of vadadustat compared to darbepoetin alfa on anemia in patients wi...
International Urology and Nephrology; Huang Q, Liao Z et. al.

Aug 13th, 2022 - As a novel oral agent in treating anemia of chronic kidney disease (CKD), several clinical trials of vadadustat have been conducted to compare with darbepoetin alfa. This study systematically reviews and investigates the efficacy and safety of vad...

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Guidelines  26 results

Controversies in optimal anemia management: conclusions from a Kidney Disease: Improvin...
Kidney International; Babitt JL, Eisenga MF et. al.

Apr 12th, 2021 - In chronic kidney disease, anemia and disordered iron homeostasis are prevalent and associated with significant adverse consequences. In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) issued an anemia guideline for managing the diagnosis,...

Spotlight: Gastrointestinal Evaluation of Iron Deficiency Anemia.
Gastroenterology Ko CW, Siddique SM et. al.

Aug 31st, 2020 - Spotlight: Gastrointestinal Evaluation of Iron Deficiency Anemia.|2020|Ko CW,Siddique SM,Patel A,Harris A,Altayar O,|blood,diagnosis,etiology,standards,standards,standards,diagnostic imaging,metabolism,pathology,standards,blood,complications,diagn...

GI Evaluation of Iron Deficiency Anemia: Clinical Decision Support Tool.

Aug 31st, 2020 - GI Evaluation of Iron Deficiency Anemia: Clinical Decision Support Tool.|2020| ,|blood,diagnosis,etiology,standards,methods,standards,standards,diagnostic imaging,metabolism,pathology,standards,blood,complications,diagnosis,pathology,analysis,diag...

AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency ...
Gastroenterology Ko CW, Siddique SM et. al.

Aug 19th, 2020 - AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency Anemia.|2020|Ko CW,Siddique SM,Patel A,Harris A,Sultan S,|blood,diagnosis,epidemiology,etiology,standards,standards,diagnostic imaging,metabolism,pathology,stan...

Management of Cancer-Associated Anemia With Erythropoiesis-Stimulating Agents: ASCO/ASH...
Journal of Clinical Oncology : Official Journal of the Am... Bohlius J, Bohlke K et. al.

Apr 11th, 2019 - To update the American Society of Clinical Oncology (ASCO)/American Society of Hematology (ASH) recommendations for use of erythropoiesis-stimulating agents (ESAs) in patients with cancer. PubMed and the Cochrane Library were searched for randomiz...

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Drugs  938 results see all →

Clinicaltrials.gov  2,779 results

Secondary Prophylaxis in Non-Hodgkin Lymphoma (NHL) and Chemotherapy-induced Thrombocytopenia

Aug 12th, 2022 - High-dose chemotherapy followed by autologous stem cell transplant is considered standard of care for patients with relapsed and/or refractory aggressive lymphomas. High-dose chemotherapy, with or without ASCT, may also be used as upfront chemothe...

Study to Assess Feasibility and Safety of Iron Repletion With Feraheme in Iron Deficient Patients With Durable Ventricular Assist Device Support

Aug 12th, 2022 - Ferumoxytol injection (Feraheme®) is a parenteral form of iron supplementation that is FDA-approved for treatment of iron deficiency anemia. Ferumoxytol injection achieves iron repletion in fewer doses (2) when compared with other available inject...

Low-Dose Danazol for the Treatment of Telomere Related Diseases

Aug 12th, 2022 - Telomere disease is caused by accelerated telomere attrition and results in multi-organ dysfunction. Telomeres are nucleotide repeats of non-coding DNA at the end of the chromosomes which function as protective caps to prevent erosion of genomic D...

Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

Aug 12th, 2022 - Background: Disorders of T-cell proliferation and/or dysregulation (TCP/D) can lead to T-cell lymphoproliferative disorders, autoimmunity, infection, and aberrant immune activation with resulting organ dysfunction, morbidity, and mortality. Alloge...

Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali

Aug 12th, 2022 - Malaria caused by Plasmodium falciparum continues to be a global problem with devastating consequences. A greater understanding of the immunologic and parasitologic factors associated with infection and disease is badly needed; and will accelerate...

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News  3,535 results

Agent Orange Exposure, Transformation From MGUS to Multiple Myeloma, and Outcomes in Veterans
Jyothi Dodlapati, MD, James A. Hall, DO et. al.

Aug 9th, 2022 - Multiple myeloma (MM) accounts for 1% to 2% of all cancers and slightly more than 17% of hematologic malignancies in the United States. 1 MM is characterized by the neoplastic proliferation of immunoglobulin (Ig)-producing plasma cells with ≥ 10% c.

CV Admissions on the Rise in Americans With Cancer

Aug 5th, 2022 - Although cardiovascular disease (CVD) is known to often strike the mortal blow in patients with cancer, a national analysis puts in stark relief the burden of CV-related hospitalizations in this vulnerable population. Results show that between 200...

A Special Supplement on Hot Topics in Primary Care 2022
MDedge Family Medicine;

Jul 25th, 2022 - Hot Topics in Primary Care 2022 is a resource that explores the newest developments in primary care topics that impact your daily clinical practice. Click on the link below to access the entire supplement.

Can early introduction of gluten reduce risk of celiac disease?
MDedge Family Medicine; Ashley U. Hall, MD, FACOG, Erica S. Meisenheimer, MD, MBA, FAAFP et. al.

Jul 20th, 2022 - ILLUSTRATIVE CASE You are seeing a 2-month-old female infant for a routine well-child visit. The birth history was unremarkable.

Essential strategies and tactics for managing sickle cell disease
MDedge Family Medicine; Robert Allen Perkins, MD, MPH, Ann Payne- Johnson, MD et. al.

Jul 18th, 2022 - The group of disorders known as sickle cell disease (SCD) is one of the more common genetic hemoglobinopathies. Homozygous production of the S variant of hemoglobin (Hb) in red blood cells (RBCs) results in profound sickling under conditions of ph.

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Patient Education  99 results see all →